Genome of bacteria. Medical search. Frequent questions

This technique could also make it possible to selectively edit, activate, or silence genes in certain species of bacteria living in a natural community such as the human microbiome, the researchers say. (scienceblog.com)
They also knocked out genes involved in a system called mismatch repair, which normally prevents integration of single-stranded DNA into the genome. (scienceblog.com)
The genome was explored using a comparative genomics approach to describe the genes that are in the genome. (umd.edu)
Genes and mobile elements were compared to other Vibrio species to determine the presence of mobile elements related to important cell functions and adaptive functions that provided evidence related to the environments in which the bacterium is able to adapt and survive. (umd.edu)
Streamlining Regulon Identification in Bacteria Regulons are a group of genes that can be turned on or off by the same regulatory protein. (doe.gov)
We've known retrons can help edit genes - now we know what they do in bacteria. (freethink.com)
Technique for editing bacterial genomes can record interactions between cells, may offer a way to edit genes in the human microbiome. (mit.edu)
The D. ficus KS 0460 genome consists of a 4.019 Mbp sequence (69.7% GC content and 3894 predicted genes) divided into six genome partitions, five of which are confirmed to be circular. (escholarship.org)
The T. thermohydrosulfuricus BSB-33 genome comprises 2597606 bp encoding 2581 protein genes, 12 rRNA, 193 pseudogenes and has a G? (pacb.com)
Furthermore, genome analysis of this strain suggested the presence of gene clusters involved in iron acquisition ( fhuABD , afuABC , fbpABC , and fepCDG ) and phosphate solubilization ( pstABCHS , phoABHLU , and phnCDEP ) and other phytohormone biosynthesis genes, including indole-3-acetic acid ( trpABCDEFG ), in the genome. (springeropen.com)
The genome sequence sheds new light on the genes and biochemical pathways in the bacterium, and the research offers a starting point for defining the mechanisms by which the organism causes disease and helping devise new strategies to detect infected animals and ultimately help control the spread of the organism. (innovations-report.com)
The analysis of the M. paratuberculosis genome found that its sequence contains nearly 5 million base pairs that are represented on a large circular chromosome with more than 4,500 predicted genes. (innovations-report.com)
The researchers assembled 84 percent of the genome identifying 28,798 genes that code for proteins. (phys.org)
The researchers identified two types of disease resistance genes in the Criollo genome. (phys.org)
The team suggests that a functional genomics approach, one that looks at what the genes do, is needed to confirm potential disease resistant genes in the Criollo genome. (phys.org)
Hidden in the genome the researchers also found genes that code for the production of cocoa butter, a substance highly prized in chocolate making, confectionary, pharmaceuticals and cosmetics. (phys.org)
The genome contains a total of 3,843 genes and 3,608 protein-coding genes, including genes supporting iron and nitrogen biogeochemical cycling. (nebraska.edu)
The phage genomes displayed modular organisation and conserved viral genes were identified which enabled further classification and determination of closest phage relatives. (qld.gov.au)
Co-examination of bacterial host genomes led to the identification of several genes responsible for modulating phage:host interactions, including CRISPR/Cas elements and restriction-modification phage defence systems. (qld.gov.au)
XDR Shigella strains can spread antimicrobial resistance genes to other enteric bacteria. (cdc.gov)
data are preliminary and based on broth microdilution susceptibility testing and/or presence of resistance genes and mutations found in whole genome sequences of bacterial DNA. (cdc.gov)

This entry is the master record for a whole genome shotgun sequencing project and contains no sequence data. (nih.gov)
To achieve that, the researchers engineered the cells to produce a reverse transcriptase enzyme called retron, which produces a single-stranded DNA (ssDNA) when expressed in the cells, and a recombinase enzyme, which can insert ("write") a specific sequence of single-stranded DNA into a targeted site in the genome. (scienceblog.com)
Tiny Earth in collaboration with JGI plans to sequence hundreds of genomes from antimicrobial-producing soil microbes and subsequently identify novel biosynthetic gene clusters. (doe.gov)
Interpreting whole-genome sequence analyses of foodborne bacteria for regulatory applications and outbreak investigations. (pacb.com)
Whole-genome sequence (WGS) analysis has revolutionized the food safety industry by enabling high-resolution typing of foodborne bacteria. (pacb.com)
2015. Genome sequence of the soil bacterium Janthinobacterium sp. (msu.edu)
We report the whole genome sequence of the extremely IR-resistant rod-shaped bacterium Deinococcus ficus KS 0460 and its phenotypic characterization. (escholarship.org)
Complete genome sequence of the chromate-reducing bacterium Thermoanaerobacter thermohydrosulfuricus strain BSB-33. (pacb.com)
Complete genome sequence of the thermophilic, piezophilic, heterotrophic bacterium Marinitoga piezophila KA3. (univ-brest.fr)
The sequencing project represents part of an ambitious "microbial pathogenomics" research program at the University of Minnesota to sequence the genomes of a wide range of human and animal pathogens and use this information as a basis to understand the mechanisms by which they cause disease. (innovations-report.com)
But fast techniques to sequence genomes have flooded the public databases and in a biased fashion, containing lots of genomic data about some species and not enough about others, according to a Rice University computer scientist. (rice.edu)
Complete genome sequence of geobacter sp. (nebraska.edu)
Dive into the research topics of 'Complete genome sequence of geobacter sp. (nebraska.edu)
Starting with more than 1,000 N. gonorrhoeae isolates collected in 20 European countries in 2013 as part of a European Gonococcal Antimicrobial Surveillance Programme, researchers from the Wellcome Sanger Institute, the European Centre for Disease Control, Örebro University, and elsewhere characterized the gonorrhea-causing pathogens with a combination of whole-genome sequencing, multilocus sequence typing (MLST), antigen sequence typing, phylogenetic analyses, and automated antibiotic resistance predictions. (genomeweb.com)
The superior resolution of [whole-genome sequence] versus NG-MAST and MLST, and linking to epidemiological data, has the potential to allow early identification of novel outbreak or high-risk clones," the authors wrote. (genomeweb.com)
The phylogenetic analysis, along with other data for the newly sequenced N. gonorrhoeae isolates from Europe, is available in an online Whole Genome Sequence Analysis database . (genomeweb.com)
On January 29, 2020, the Institut Pasteur, which is responsible for monitoring respiratory viruses in France, sequenced the whole genome of the coronavirus known as "2019-nCoV", becoming the first institution in Europe to sequence the virus since the start of the outbreak. (pasteur.fr)
Over the weekend of January 11-12, the Chinese authorities shared the full sequence of the coronavirus genome, as detected in samples taken from the first patients. (pasteur.fr)
The sequencing run was completed by early evening on the Tuesday, and the scientists used data analysis to obtain the sequence of the whole genome in two of the first three confirmed cases in France. (pasteur.fr)
The authors of the Comparative Genomics article conducted a more extensive whole genome sequence analysis, in which they compared nine outbreak-related isolates with 12 contemporary Asian or African isolates matched on PFGE pattern and 2 non-matching isolates from the Western hemisphere. (cdc.gov)
Furthermore, a phylogenetic analysis incorporating previously reported whole genome sequence data found that the Haitian isolates were indistinguishable from one of four closely related genetic clusters among the isolates from Nepal. (cdc.gov)
Just as PFGE testing relies on comparison with archived data (as in PulseNet ), the public health value of high-resolution genome sequences depends on the availability of appropriate, high-quality sequence data for comparison. (cdc.gov)
Genome Sequence of Geobacillus sp. (lu.se)
Complete genome sequence of the endophytic bacterium Cellulosimicrobium sp. (bvsalud.org)
Complete Genome Sequence of Paenibacillus sp. (bvsalud.org)

Analysts often count the numbers of nucleotide differences [single-nucleotide polymorphisms (SNPs)] between two or more genome sequences to measure genetic distances. (pacb.com)
These populations are subject to evolutionary forces that can change genome sequences. (pacb.com)
The aim of this study is to investigate the adaptation of bifidobacterial species to various hosts and to examine the genetic biodiversity of bifidobacterial species from various hosts like human, non-human primates, bat and other organisms by decoding genome sequences. (soken.ac.jp)
The researchers also found that the chromosome has a large number of sequences repeated throughout the genome. (innovations-report.com)
Todd Treangen and his colleagues tested taxonomic classification methods that match genomic sequences from bacteria of interest with those recorded in large databases to identify species. (rice.edu)
The study, based on sequenced genomes from samples, was later revised to reflect mismatches that falsely identified the sequences as Bacillus anthracis. (rice.edu)
In this process, the different sequences shed light on the types of bacteria contained in a sample. (sciencebulletin.org)
Interestingly, only 20 percent of the genome was made up of transposable elements, one of the natural pathways through which genetic sequences change," said Guiltinan "They do this by moving around the chromosomes, changing the order of the genetic material. (phys.org)
The researchers were able to reclassify some of N. gonorrhoeae isolates based on the presence or absence of known resistance mutations in the genome sequences and follow-up testing on isolates that appeared to be phenotyped incorrectly. (genomeweb.com)
Here we report the first complete genome sequences of lytic phage isolates specifically infecting three genera of rumen bacteria: Bacteroides, Ruminococcus and Streptococcus. (qld.gov.au)

Biological engineers at MIT have devised a new way to efficiently edit bacterial genomes and program memories into bacterial cells by rewriting their DNA. (scienceblog.com)
With this new DNA writing system, we can precisely and efficiently edit bacterial genomes without the need for any form of selection, within complex bacterial ecosystems," says Fahim Farzadfard, a former MIT postdoc and the lead author of the paper. (scienceblog.com)
With those modifications, the researchers were able to achieve near-universal incorporation of the genetic changes that they tried to introduce, creating an unparalleled and efficient way for editing bacterial genomes without the need for selection. (scienceblog.com)
The replication-related organization of bacterial genomes. (harvard.edu)
Our work reveals how the evolution of bacterial genomes is structured by fundamental constraints rooted in metabolism. (tau.ac.il)

Researchers from The University of Texas at Austin have been working to develop a genetically engineered bacteria that will modify the microbiome of honeybees. (genomebc.ca)
By evaluating how these bacteria have become resistant and how the microbiome changes, we can determine how various phages affect virulence. (apple.com)
Silver Age of GOLD Introduces New Features The Genomes OnLine Database makes curated microbiome metadata that follows community standards freely available and enables large-scale comparative genomics analysis initiatives. (doe.gov)
The microbiome is home to an estimated 100 trillion bacteria living in a dense colony of many different strains and species. (mpg.de)
These findings provide new genetic information and insights into how lytic phages may interact with bacteria of the rumen microbiome. (qld.gov.au)

Nahant, Massachusetts, January 24, 2023 - The Ocean Genome Legacy Center (OGL) is a new Environmental Partner of 1% for the Planet, an alliance of more than 5,400 business and individual members that give back to support environmental nonprofits. (northeastern.edu)

There is also extensive size variation within a species, with strains of some species differing by more than 50 % in genome size (primary sources). (harvard.edu)
Unlike other T. thermohydrosulfuricus strains, BSB-33 is able to anaerobically reduce Fe(III) and Cr(VI) optimally at 60 °C. BSB-33 is the first Cr(VI) reducing T. thermohydrosulfuricus genome sequenced and of particular interest for bioremediation of environmental chromium contaminations. (pacb.com)
Here we describe the major differences at the genomic level between seven grapevine endophytic test bacteria, and 12 reference strains. (fmach.it)
We show that whole-genome sequencing gives a true picture of where sensitive and resistant strains are circulating, which will allow doctors to quickly spot the emergence of new, antibiotic resistant gonorrhea strains," first author Simon Harris, a pathogen genomics researcher at the Wellcome Sanger Institute, said in a statement. (genomeweb.com)
The virus was sequenced at the Institut Pasteur's Mutualized Platform for Microbiology (P2M), which performs genome sequencing on bacterial, viral, fungal and parasite strains received by National Reference Centers and World Health Organization Collaborating Centers for the purpose of infectious disease surveillance. (pasteur.fr)
At least 26 strains of S. thermophilus have been identified and had their genomes sequenced. (wikipedia.org)
Research teams have sequenced the genome of two strains of S. thermophilus , CNRZ1066 and LMG13811, and stated that the bacteria are not dangerous. (wikipedia.org)
In the experiment, two different strains of bacteria are used to make reduced-fat cheddar cheese: a strain of Lactococcus lactis and a strain of S. thermophilus . (wikipedia.org)
CDC defines XDR Shigella bacteria as strains that are resistant to all commonly recommended empiric and alternative antibiotics - azithromycin, ciprofloxacin, ceftriaxone, trimethoprim-sulfamethoxazole (TMP-SMX), and ampicillin. (cdc.gov)

See how the University of Washington used HiFi sequencing to uncover a key finding about ALS and the human genome. (pacb.com)
Model of the human genome. (lifeboat.com)
The National Human Genome Research Institute provides a definition of gene regulation in their Talking Glossary of Genetic Terms. (medlineplus.gov)
The mapping of the human genome was completed in 2000 and opened up possibilities to develop personalised medicines. (lu.se)

The new DNA writing technique, which the researchers call HiSCRIBE, is much more efficient than previously developed systems for editing DNA in bacteria, which had a success rate of only about 1 in 10,000 cells per generation. (scienceblog.com)
As one example, the researchers showed that they could track a process called bacterial conjugation, during which bacteria exchange pieces of DNA. (scienceblog.com)
By integrating a DNA "barcode" into each cell's genome, which can then be exchanged with other cells, the researchers can determine which cells have interacted with each other by sequencing their DNA to see which barcodes they carry. (scienceblog.com)
This kind of mapping could help researchers study how bacteria communicate with each other within aggregates such as biofilms. (scienceblog.com)
However, CRISPR techniques have allowed researchers to pinpoint how a bacterium is resistant and alter it at a genomic level. (apple.com)
Genome Insider: Methane Makers in Yosemite's Lakes Meet researchers who sampled the microbial communities living in the mountaintop lakes of the Sierra Nevada mountains to see how climate change affects freshwater ecosystems, and how those ecosystems work. (doe.gov)
Supercharging SIP in the Fungal Hyphosphere Applying high-throughput stable isotope probing to the study of a particular fungi, researchers identified novel interactions between bacteria and the fungi. (doe.gov)
But with two projects, communities are forming to generate high quality genomes to benefit researchers. (doe.gov)
One alternative to using oilseed crops that many bioenergy researchers are exploring is to synthesize the fatty acids that are converted into biodiesel in bacteria. (doe.gov)
According to Science, researchers recognized retron's genome-editing potential even before knowing its Dr. Strangelove -esque raison d'être. (freethink.com)
University of Minnesota researchers, with collaborators at the U. S. Department of Agriculture s National Animal Disease Center in Ames, Iowa, have completed sequencing the genome of the bacteria that causes Johne s disease, a major chronic wasting disease found in dairy cattle. (innovations-report.com)
This week, a team of researchers-including student scientists-from Northeastern University's Ocean Genome Legacy Center (OGL) published a discovery that may be a game changer for DNA preservation. (northeastern.edu)
In another study published in the same issue of PNAS, a team led by researchers from the Max Planck Institute of Neurobiology with contributions from Cekanaviciute and UCSF colleague Sergio Baranzini compared the gut microbiota of 34 monozygotic twin pairs discordant for MS. While they found no major differences in the overall human microbial composition, the researchers saw a significant increase in bacteria such as A. muciniphila. (genomeweb.com)
For example, the researchers found that at least one MS-associated bacteria could confuse the immune system into attacking myelin as well as the bacteria. (genomeweb.com)

We describe the virulence factors detected in the genomes of the test group, as compared to endophytic and non-endophytic references, to better understand the distribution of these traits in endophytic genomes. (fmach.it)
JZ18, a Root Endophytic Bacterium Isolated from the Perennial Desert Tussock-Grass Panicum turgidum. (bvsalud.org)
JZ16, a Plant Growth Promoting Root Endophytic Bacterium of the Desert Halophyte Zygophyllum Simplex. (bvsalud.org)

These bacteria may contribute to plant growth and health by assisting in nutrient uptake or by suppressing plant pathogens (Vejan et al. (springeropen.com)
Another role that these bacteria have is producing compounds that likely protect their host shipworms from pathogens. (northeastern.edu)
Sequencing the genome of pathogens is crucial for the development of specific diagnostic tests and the identification of potential treatment options," explains Sylvie van der Werf, Director of the National Reference Center (CNR) for Respiratory Viruses at the Institut Pasteur. (pasteur.fr)
Many of the bacteria that have acquired a chitin synthase are plant pathogens (e.g. (biomedcentral.com)

In this study a genome wide comparative analysis of bifidobacterial species from different hosts was done. (soken.ac.jp)
The genetic platforms of Deinococcus species remain the only systems in which massive ionizing radiation (IR)-induced genome damage can be investigated in vivo at exposures commensurate with cellular survival. (escholarship.org)
M. paratuberculosis is a slow-growing bacterium that causes a chronic gastrointestinal infection in dairy cattle and other small ruminant species (such as sheep, goat, and deer) and has both serious health and economic consequences to dairy farming worldwide. (innovations-report.com)
There are many ways to slice and dice genomic data to identify a species of bacteria, or at least find its close relatives. (rice.edu)
Smaller amounts of transposons than found in other plant species could lead to slower evolution of the chocolate plant, which was shown to have a relatively simple evolutionary history in terms of genome structure. (phys.org)
They identified distinct species of bacteria that were in higher concentrations in people with MS than in the general population. (genomeweb.com)
[10] Although its genus, Streptococcus , includes some pathogenic species, food industries consider S. thermophilus a safer bacterium than many other Streptococcus species. (wikipedia.org)

Overall, physiological testing and genome analysis data provide comprehensive insights into plant growth-promoting mechanisms, suggesting the relevance of strain ATSA2 T in agricultural biotechnology. (springeropen.com)
A study co-author, Dr. Donald Low, chief microbiologist at Mount Sinai Hospital in Toronto, said in the news release that 'until now it has been a mystery why sometimes we see two opposing types of infection in patients who appear to have the same strain of flesh-eating bacteria. (healthday.com)
The complete genome information coupled with biochemical assays confirms that strain RA is able to degrade cellulose and xylan. (um.edu.my)
Genetic analyses of the outbreak strain-first by pulsed field gel electrophoresis (PFGE) and later by whole genome sequencing -were undertaken to characterize its virulence, origins, and spread. (cdc.gov)
Furthermore, the initial whole genome sequencing study had limited capacity to explore the origins of the outbreak strain because it lacked recent, globally distributed isolates for comparison. (cdc.gov)
Strain ZGt-1, an Antibacterial Peptide-Producing Bacterium from Hot Springs in Jordan. (lu.se)

Therefore, interpreting WGS analyses of foodborne bacteria requires a more sophisticated approach. (pacb.com)
Putative chromate reductases were identified by comparative analyses with other Thermoanaerobacter and chromate-reducing bacteria. (pacb.com)
The current study was reliant upon genome analyses performed previously from other international studies. (cdc.gov)

This document specifies the minimum requirements for generating and analysing whole genome sequencing (WGS) data of bacteria obtained from the food chain. (iso.org)
Our revolutionary sequencing technologies combine the completeness of long reads with the accuracy of short reads to provide the most comprehensive view of genomes, transcriptomes, and epigenomes. (pacb.com)
MONDAY, Jan. 25, 2010 (HealthDay News) -- The sequencing of nearly 100 full genomes from three successive epidemics of flesh-eating bacteria have given scientists the first clear picture of the biological events that contribute to deadly epidemics of severe infection. (healthday.com)
The production of high quality chocolate, and the farmers who grow it, will benefit from the recent sequencing and assembly of the chocolate tree genome, according to an international team led by Claire Lanaud of CIRAD, France, with Mark Guiltinan of Penn State, and including scientists from 18 other institutions. (phys.org)
That same Friday evening, scientists launched the process of sequencing the viral genome based on the samples. (pasteur.fr)
While bacterial genome sequencing projects are revealing the presence of phages which can integrate their DNA into the genome of their host to form stable, lysogenic associations, little is known of the genetics of phages which utilise lytic replication. (qld.gov.au)
Whole genome sequencing offers increased capacity for comparing and distinguishing among genotypes of pathogen isolates. (cdc.gov)
Vanillin production in Pseudomonas: whole-genome sequencing of Pseudomonas sp. (lu.se)

This could one day allow for the engineering of bacteria with improved pathogen suppression capabilities useful for antibacterial and antifungal applications", John Whitney says. (mpg.de)
The slow-growing nature of this bacterium has been an impediment to the diagnosis of infected animals and has also served as a major obstacle for laboratory based research on the pathogen," said Kapur. (innovations-report.com)

Antimicrobial resistance in enteric bacteria: current state and next-generation solutions. (cdc.gov)

2016 ). Indirect mechanisms promote plant growth through the inhibition of phytopathogens, for example, via inhibition of soil-borne fungi, bacteria, and nematodes through the production of antimicrobial metabolites or siderophores (Fu et al. (springeropen.com)
The beneficial bacterium Pseudomonas protegens protects plants from fungi and bacteria. (mpg.de)

This modified bacteria is designed specifically to live in honeybees to limit any potential spread to other organisms. (genomebc.ca)
The study provides insight into the unique electrogenic metabolism of the cable bacteria as well as the evolutionary origin of these intriguing micro-organisms. (microbial-electricity.eu)
Like all organisms, bacteria are in a constant competition for space and resources. (mpg.de)
Bacteria are unicellular organisms present on Earth can thrive in various environments, including the human body. (wikipedia.org)
Only a few years ago, it was still believed that single-celled organisms with several genome copies were the exception. (sciencebulletin.org)
Shigella bacteria are easily transmitted because of the low infectious dose (as few as 10-100 organisms), and outbreaks tend to occur among people in close-contact settings [2-6]. (cdc.gov)

Heterotrophic bacteria-bacteria that utilize organic carbon sources-are taxonomically and functionally diverse across environments. (tau.ac.il)
We show that, despite high variability at all levels of taxonomy, the catabolic niches of heterotrophic bacteria can be understood in terms of their preference for either glycolytic (sugars) or gluconeogenic (amino and organic acids) carbon sources. (tau.ac.il)
Cordero, Otto X. / Genome content predicts the carbon catabolic preferences of heterotrophic bacteria . (tau.ac.il)

Here we characterise phylogenetically diverse genome-encoded ABCFs from Actinomycetia (Ard1 from Streptomyces capreolus, producer of the nucleoside antibiotic A201A), Bacilli (VmlR2 from soil bacterium Neobacillus vireti) and Clostridia (CplR from Clostridium perfringens, Clostridium sporogenes and Clostridioides difficile). (lu.se)
Plant-associated bacteria ubiquitously inhabit the rhizosphere (soil-root interface), phyllosphere (aerial surfaces), and endosphere (inside of the plant tissues). (springeropen.com)
S1 and Achromobacter spanius s4, two syringol metabolizing bacteria isolated from compost soil. (lu.se)

The genome also provided insight into nutrients that the bacterium may be able to metabolize. (umd.edu)
The genome provides insight into the ecological strategies of this bacterium in free-living and host-associated environments. (msu.edu)

O'Connor, who began this research while working at OGL before moving to Washington State University, showed that the compound tartrolon (trtE), produced by the symbiotic bacterium, is incredibly effective at targeting parasites and acts very quickly: it killed the parasites after only two hours of treatment. (northeastern.edu)

Genome-encoded antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F subfamily (ARE-ABCFs) mediate intrinsic resistance in diverse Gram-positive bacteria. (lu.se)

Phenotypic and genotypic characterization of antibiotic resistance in military hospital-associated bacteria from war injuries in the Eastern Ukraine conflict between 2014 and 2020. (cdc.gov)

This enables us to perform genome editing and DNA writing outside of laboratory settings, whether to engineer bacteria, optimize traits of interest in situ, or study evolutionary dynamics and interactions in the bacterial populations. (scienceblog.com)

The Genome of Vibrio orientalis : A Luminous Bacterium. (umd.edu)
Vibrio orientalis was first isolated from the Yellow Sea in China and described as a luminous bacterium. (umd.edu)
But there would have been no epidemic without the bacterium, Vibrio cholerae . (cdc.gov)

Interestingly, the secondary metabolites cerecidin, carotenoid, siderophore (staphylobactin), and bacillaene underlying plant growth promotion were found in the whole genome via antiSMASH analysis. (springeropen.com)
Single-cell genomes and metagenomic analysis showed that the many chromosomes are not identical copies of one another. (sciencebulletin.org)
Our analysis of the Criollo genome has uncovered the genetic basis of pathways leading to the most important quality traits of chocolate -- oil, flavonoid and terpene biosynthesis," said Siela Maximova, associate professor of horticulture, Penn State, and a member of the research team. (phys.org)
A genome-wide analysis resulted in the detection of more than eight hundred putative chitin synthases in proteomes associated with about 130 genomes. (biomedcentral.com)
Identification of putative novel class-I lanthipeptides in firmicutes: A combinatorial in silico analysis approach performed on genome sequenced bacteria and a close inspection of Z-geobacillin lanthipeptide biosynthesis gene cluster of the Thermophilic geobacillus sp. (lu.se)

To do this, we adopted a comparative whole-genome approach, encompassing BLAST-based searches through the GUI-based tools Mauve and BRIG as well as calculating the core and accessory genomes of three genera of enterobacteria. (fmach.it)

The rumen is known to harbour dense populations of bacteriophages (phages) predicted to be capable of infecting a diverse range of rumen bacteria. (qld.gov.au)
While lytic phages for rumen bacteria have been previously isolated, their genomes have remained largely uncharacterised. (qld.gov.au)

the draft genome consists of five contigs. (umd.edu)

Tracing the Evolution of Shiitake Mushrooms Understanding Lentinula genomes and their evolution could provide strategies for converting plant waste into sugars for biofuel production. (doe.gov)
Genome Evolution of Photosynthetic Bacteria. (koeltz.com)

We present a draft genome of Janthinobacterium sp. (msu.edu)
Draft genome assembly of Stutzerimonas sp. (lu.se)

in fact, its immune system is so good it has been borrowed by humans to do genome editing with the famous CRISPR system. (freethink.com)
CRISPR is really good at acting like an x-acto knife, cutting up the parts of the genome we want it to - but it isn't as adept at inserting new genetic code into the DNA. (freethink.com)
Retrons' reverse transcriptase can whip up lots of the DNA we want, which can then be inserted into the genome where CRISPR cuts it. (freethink.com)
But there is, of course, a catch: retron genome editing hasn't been shown to work in mammalian cells, yet - the same situation was CRISPR in, eight years ago. (freethink.com)

PFGE is currently the method of choice for subtyping of pathogenic bacteria in outbreak investigations. (cdc.gov)

Streptococcus" derives from a Greek term meaning "twisted kernel" and refers to the way the bacterium is grouped in chains that resemble a string of beads. (wikipedia.org)

iPHoP: A Matchmaker for Phages and their Hosts Building on existing virus-host prediction approaches, a new tool combines and evaluates multiple predictions to reliably match viruses with their archaea and bacteria hosts. (doe.gov)
Their research, published in Cell, demonstrates that retrons are a failsafe, a kind of cellular cyanide pill that ensures if its other defenses fail, the infected bacteria dies before the phages can use it to crank out enough copies to infect other bacteria around them. (freethink.com)
Phages and bacteria have been in an arms race longer than you can imagine, so phages had to figure out a way around RecBCD to survive. (freethink.com)
Owing in part to the inability of phages to attach to spores, seed banks stabilized population dynamics and resulted in minimum host densities that were 30-fold higher compared to bacteria that were unable to engage in dormancy. (nature.com)

How bacteria become resistant How the virome reacts to gaining resistance How bacteria avoid the immune system Gaetan Burgio, a group leader of the Burgio Group as a part of Australia National University, shares his experience working with AMR bacteria. (apple.com)
Lacking this bacteria might encourage the immune system to overreact to harmless microbes in people with MS, causing harmful inflammation. (genomeweb.com)

Protein post-translational modifications (PTMs) represent important regulatory states that when combined have been hypothesized to act as molecular codes and to generate a functional diversity beyond genome and transcriptome. (nih.gov)
If, however, the sample also contains Achromatium or similar polyploid bacteria, the method used to date may lead to an overestimation of the true diversity. (sciencebulletin.org)

Parabacteroides distasonis , a bacteria found at lower than usual levels in MS patients, triggered an immune-regulatory response as well. (genomeweb.com)
Whipple pointed out the existence of great numbers of peculiar rod-shaped bacteria found in extracts of lymph node tissue and lamina propria of the intestine. (medscape.com)

Another mysterious component in bacteria, called a retron, has puzzled scientists for years, but now, Science reports, we finally know exactly what it's for - and how we could use it to level up genome editing. (freethink.com)

NEW YORK (GenomeWeb) - An international team has established a cross-Europe genomic database of Neisseria gonorrhoeae , the bacterium behind the sexually transmitted infection gonorrhea, using the data to trace antibiotic resistance patterns on the continent. (genomeweb.com)
Research led by former Ocean Genome Legacy (OGL) scientist, Dr. Roberta O'Connor , now an associate professor at Washington State University, investigates whether a new antibiotic made by shipworm bacteria to protect their host can also be used by humans to treat parasitic infections. (northeastern.edu)

The honeybees in this study were sprayed with these beneficial bacteria which they then ingested. (genomebc.ca)

Often, they are instead the product of the metabolism of yeast and bacteria and are modified and released in wine during the fermentation processes. (frontiersin.org)

A new study is published in the scientific journal Proceedings of the National Academy , which reveals the genome of the cable bacteria. (microbial-electricity.eu)

We systematically investigate the interplay of protein phosphorylation with other post-transcriptional regulatory mechanisms in the genome-reduced bacterium Mycoplasma pneumoniae. (nih.gov)
This is in part because the E. coli have cellular mechanisms that prevent single-stranded DNA from being accumulated and integrated into their genomes. (scienceblog.com)

In this report, we report on the resequencing of its complete genome using a PacBio RSII platform. (um.edu.my)

The genome project-supported by the USDA through the Cooperative State, Research, Education & Extension Service s (CSREES) National Research Initiative Competitive Grants Program and the Agricultural Research Service (ARS)-is expected to provide a boost to wide-ranging research efforts for the development of the next generation of antimicrobial agents and vaccines to protect cattle against infection with the bacterium. (innovations-report.com)

Anatomy13

Organisms53

Diseases4

Chemicals and Drugs33

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes117

Disciplines and Occupations9

Technology, Industry, Agriculture3

Information Science11

Health Care13

Genes21

Sequence25

Sequences10

Bacterial genomes5

Microbiome5

20231

Strains9

Human genome4

Researchers14

Endophytic3

Pathogens4

Species7

Strain6

Analyses3

Sequencing8

Pathogen2

Enteric bacteria1

Fungi2

Organisms6

Heterotrophic3

Soil3

Insight2

Symbiotic1

Proteins1

20201

Evolutionary1

Vibrio3

Analysis5

Genera1

Rumen2

Consists1

Evolution2

Draft2

CRISPR4

Pathogenic1

Streptococcus1

Phages4

Immune system2

Diversity2

Found2

Scientists1

Antibiotic2

Beneficial1

Metabolism1

Reveals1

Mechanisms2

Complete1

USDA1