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  • mtDNA
  • Study director Professor Lisa Matisoo-Smith explains that mitochondrial DNA (mtDNA) is only inherited through the mother's side and can be used to trace maternal lineages and provide insights into ancient origins and migration routes. (eurekalert.org)
  • In this study, we determined the whole mitochondrial DNA (mtDNA) sequences of seven sharks including representatives of the five Hexanchiformes, one squaliform, and one carcharhiniform and inferred the phylogenetic relationships among those species and 12 other Chondrichthyes (cartilaginous fishes) species for which the complete mitogenome is available. (hindawi.com)
  • Sequencing
  • In a landmark study, University of Otago researchers have achieved the feat of sequencing complete mitochondrial genomes for members of what was likely to be one of the first groups of Polynesians to settle New Zealand and have revealed a surprising degree of genetic variation among these pioneering voyagers. (eurekalert.org)
  • Until the advent of next generation sequencing techniques, the highly degraded state of DNA in human remains of this age has not allowed such genomes to be sequenced," she says. (eurekalert.org)
  • genetic
  • The researchers discovered that the four genomes shared two unique genetic markers found in modern Maori while also featuring several previously unidentified Polynesian genetic markers. (eurekalert.org)
  • evolution
  • The extraordinary level of conservation of the tulip tree ( Liriodendron tulipifera ) mitochondrial genome has redefined our interpretation of evolution of the angiosperms (flowering plants), finds research in biomed Central's open access journal BMC Biology . (redorbit.com)
  • Initial interest in mutations occurring in mitochondrial DNA of cancer cells diminished when most were found to be the same mutations which occurred during the evolution of human mitochondrial haplogroups. (hindawi.com)
  • 2010 . A role for nonadaptive processes in plant genome size evolution? (wiley.com)
  • A team of researchers has carried out a detailed study of the genomes of ruminants, giving new insight into their evolution and success. (wn.com)
  • Models of evolution of the genome structure and HCEs initially faced considerable algorithmic challenges, which gave rise to (often unnatural) constraints on these models, even for conceptually simple tasks such as the calculation of distance between two structures or the identification of UCEs. (mdpi.com)
  • These approaches have led us to an unexpected result: for some organelles and taxa, the genome structure and HCE set, despite themselves containing relatively little information, still adequately resolve the evolution of species. (mdpi.com)
  • We also used the HCE identification to search for promoters and regulatory elements that characterize the functional evolution of the genome. (mdpi.com)
  • Gershgorin RA, Gorbunov KY, Zverkov OA, Rubanov LI, Seliverstov AV, Lyubetsky VA. Highly Conserved Elements and Chromosome Structure Evolution in Mitochondrial Genomes in Ciliates. (mdpi.com)
  • analyses
  • Possibly, it may have been missed due to most previous work only focusing on a small portion of the mitochondrial genome rather than complete analyses like ours. (eurekalert.org)
  • (pnas.org)
  • Several different methods have been employed to unravel the cellular processes and components involved in the dynamic rearrangements of mitochondrial compartments, including electron and fluorescent microscopy coupled to biochemical and genetic analyses. (genetics.org)
  • variation
  • In a landmark study, University of Otago researchers have achieved the feat of sequencing complete mitochondrial genomes for members of what was likely to be one of the first groups of Polynesians to settle New Zealand and have revealed a surprising degree of genetic variation among these pioneering voyagers. (eurekalert.org)
  • The robust Affymetrix GeneChip Human Mitochondrial Resequencing Array 2.0 provides a complete picture of variation in the mitochondrial genome, while significantly reducing the time, labor and cost involved in sample preparation," said Greg Yap, vice president of DNA Products at Affymetrix. (technologynetworks.com)
  • It has been postulated that substoichiometric shifting may have evolved to permit the species to create and retain mitochondrial genetic variation in a silenced but retrievable form ( 22 ). (pnas.org)
  • PNAS
  • Results from the team's successful mapping of complete mitochondrial genomes of four of the Rangitane iwi (tribe) tupuna (ancestors) who were buried at a large village on Marlborough's Wairau Bar more than 700 years ago will be published online in the prestigious US journal Proceedings of the National Academy of Sciences ( PNAS ). (eurekalert.org)
  • human
  • The microarray interrogates all 16,500 bases of the human mitochondrial genome with only three polymerase chain reactions (PCR), providing scientists with the efficient method for detecting variants associated with genetic disease, forensics, population studies or stem cells. (technologynetworks.com)
  • variants
  • A genome-wide association study that linked common genetic variants to salivary gland carcinoma risk has been retracted, according to Retraction Watch. (genomeweb.com)
  • molecules
  • The published data indicate that flowering plants contain the largest mitochondrial genomes reported so far, consisting of heterogeneous populations of mainly linear and sometimes circular DNA molecules. (frontiersin.org)
  • Their presence in direct orientation permits the subdivision of the genome into a collection of molecules, each containing only a portion of the genetic information. (pnas.org)
  • researchers
  • The researchers discovered that the four genomes shared two unique genetic markers found in modern Maori while also featuring several previously unidentified Polynesian genetic markers. (eurekalert.org)
  • protein
  • Endo T, Nakayama Y, Nakai M (1995) Avidin fusion protein as a tool to generate a stable translocation intermediate spanning the mitochondrial membranes. (springer.com)
  • This double-mutant phenotype allowed cloning of YME6 , which is identical to MMM1 and encodes an outer mitochondrial membrane protein essential for maintaining normal mitochondrial morphology. (genetics.org)
  • Biology
  • In Genome Biology this week: peopling of the Sahara, epigenetic reprogramming analysis of liverwort, and more. (genomeweb.com)