Genome expression profiling. Medical search. Frequent questions

Frequent whole-genome duplication (WGD) and dispersed duplication (DSD) were the major driving forces underlying the bZIP gene family in Chinese white pear. (udl.cat)
PbbZIP gene occurred through Whole-genome duplication and dispersed duplication events. (udl.cat)
Whole-genome sequencing showed that historic and recent isolates of B. pertussis have substantial variation in genome organization and form separate phylogenetic clusters. (cdc.gov)

DMRs show continuous gain or loss of methylation during differentiation, and the overall change in DNA methylation correlates inversely with gene expression at key loci. (lu.se)
Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation. (lu.se)

The long non-coding RNA expression was consistent with the results of the microarray test and could have a potential role in the development of stable angina pectoris. (ijpsonline.com)
In this study, we tried to identify differentially expressed genes between largest (F1) and second-largest follicles (F2), and classify them by global gene expression profiling using a combination of microarray and quantitative real-time PCR (QPCR) analysis. (biomedcentral.com)
Techniques include DNA microarray technology or sequenced-based techniques such as serial analysis of gene expression (SAGE). (wikipedia.org)
Background Microarray gene manifestation profiling provides an unbiased, comprehensive look at of an entire molecular system, and is well suited to identify the relevant factors define the cancers phenotype. (cell-metabolism.com)
Total RNA was isolated from samples and subjected to cDNA microarray analysis with the use of the human genome U133A GeneChip oligonucleotide microarray (Affymetrix, Santa Clara, CA), which allows to analyze a total number of 14,500 genes in the same time. (unicatt.it)
Microarray analysis is a molecular technique that enables the parallel analysis of expression by a very large number of genes encompassing a significant fraction of the human genome. (molcells.org)
In the present study, we use mRNA microarray to acquire differential expression profiles in human TAD tissues and non-TAD tissues. (hindawi.com)
Different expression of miRNAs in exosomes across all the three groups were screened using miRNA microarray method. (biomedcentral.com)
Further validation indicated that the 4 significant differentially expressed candidate miRNAs (miR-671-5p, miR-16-5p, miR-150-3p, and miR-4281) in exosome showed the same changes as in the microarray analysis, and the expression level of three miRNAs (miR-671-5p, miR-16-5p, and miR-150-3p) were significantly different between MHFMD or ESHFMD and the healthy controls. (biomedcentral.com)
The design and construction of a DNA microarray for any given microbial genome are straightforward. (medscape.com)

We also found that SRC-3 depletion in cultured HESCs results in a significant attenuation in the induction of a wide-range of established biomarkers of decidualization, despite exposure of these cells to a deciduogenic stimulus and normal progesterone receptor expression. (frontiersin.org)
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis. (cienciavida.org)
In seeking more specific biomarkers of the cystic fibrosis (CF) lung inflammatory disease that would be sensitive to antibiotic therapy, we sought to evaluate the gene expression profiles of neutrophils in CF patients before treatment in comparison with non-CF healthy individuals and after antibiotic treatment. (unifg.it)
Exosomal miRNA expression profiles may provide supplemental biomarkers for diagnosing and subtyping HFMD infections. (biomedcentral.com)
However, there are many new biomarkers that have been incorporated into the AJCC 8th Edition as a component of prognostic stage and will be collected starting in January 2018, if they are not already part of routine surveillance (such as breast cancer gene expression profiling and human papilloma virus). (cdc.gov)
For example, the 2015 annual report showed breast cancer incidence by molecular subtypes using tumor biomarkers for hormone receptor (HR) and human growth factor-neu receptor (HER2) expression. (cdc.gov)

We find that the potato genome substantially expanded its repertoire of disease-resistance genes when compared with closely related seed-propagated solanaceous crops, indicative of the effect of tuber-based propagation strategies on the evolution of the potato genome. (nature.com)
Based on the available public RNA-Seq data, the expression patterns of PgGRF and PgGIF genes were analysed from 14 different tissues. (biomedcentral.com)
The WRC domain can be combined with the cis-acting regions of downstream genes to regulate their expression. (biomedcentral.com)
Global gene expression profiles of F1 (10.7 +/- 0.7 mm) and F2 (7.8 +/- 0.2 mm) were analyzed by hierarchical cluster analysis and expression profiles of 16 representative genes were confirmed by QPCR analysis. (biomedcentral.com)
Cluster A was composed of only F2 and was characterized by high expression of 31 genes including IGFBP5, whereas cluster B contained only F1 and predominantly expressed 45 genes including CYP19 and FSHR. (biomedcentral.com)
Expression of stage-specific genes in follicles may be closely associated with their growth or atresia. (biomedcentral.com)
Gene expression profiling is a technique used in molecular biology to query the expression of thousands of genes simultaneously. (wikipedia.org)
While almost all cells in an organism contain the entire genome of the organism, only a small subset of those genes is expressed as messenger RNA (mRNA) at any given time, and their relative expression can be evaluated. (wikipedia.org)
Dr. Gazdar and Dr. Girard developed a 62-gene mRNA expression signature as an adjunct test for routine histopathological classification of NSCLCs, which includes many genes used in immunostains for NSCLC typing. (genomeweb.com)
Dr. Lo and colleagues have shown in a pilot study that they can use the HTG EdgeSeq Oncology Biomarker Panel to profile approximately 2,500 genes from a cohort of microdissected low- and high-grade PanIN lesions from human pancreatic cancer resections that have been archived as FFPE tissue blocks. (genomeweb.com)
For genes of interest, real-time RT-PCR was performed to confirm their expression level. (unicatt.it)
Regarding ruptured aneurysms, genes were identified showing differential expressions (overexpressed or downregulated) pertaining to specific pathways, particularly those for the structural proteins of the extracellular matrix, members of matrix metalloproteinase (MMP) family (which resulted as being overexpressed) and genes involved in apoptotic phenomena. (unicatt.it)
Parthenogenetic blastocysts exhibited changes in the expression of 749 genes, of which 214 had lower expression and 535 showed higher expressions than fertilized embryos using a minimal 1.8-fold change as a cutoff. (prinsesmaximacentrum.nl)
Genes important for placenta development were decreased in their expression in parthenote blastocysts. (prinsesmaximacentrum.nl)
The expression of several imprinted genes was altered in parthenote blastocysts. (prinsesmaximacentrum.nl)
Our findings suggest that failed X inactivation, aberrant imprinting, decreased ERK/MAPK signaling and possibly elevated Wnt signaling, and reduced expression of genes for placental development collectively may contribute to abnormal placenta formation and failed fetal development in parthenogenetic embryos. (prinsesmaximacentrum.nl)
They bind to the CCAAT box in the promoter regions of the target genes and regulate gene expressions. (icrisat.org)
In silico analysis of Sorghum bicolor genome resulted in the identification of a total of 42 NF-Y genes, among which 8 code for the SbNF-YA, 19 for SbNF-YB and 15 for the SbNF-YC subunits. (icrisat.org)
Expression pattern of PbbZIP genes differential expressed under hormonal treatment abscisic acid, salicylic acid, and methyl jasmonate in pear fruits by real-time qRT-PCR. (udl.cat)
Differential expression of 11 TabZIP genes in anther of TY806, BS366 and their hybrid F1. (biomedcentral.com)
These 11 TabZIP genes were sorted into three distinct gene expression modes based on their deviation from the mid-parent prediction: over-dominance, under-dominance and low-parent dominance. (biomedcentral.com)
In the present study, a total of 13, 12, 8 and 8 candidate fatty acid desaturases genes were identified in the Aspergillus oryzae , Aspergillus flavus , Aspergillus fumigatus and Aspergillus nidulans genomes through database searches, which were classified into five different subfamilies based on phylogenetic analysis. (springeropen.com)
In addition, the expression pattern of 13 fatty acid desaturases genes of A. oryzae was tested in different growth stages and under salt stress treatment. (springeropen.com)
characterized 19 genes encoding fatty acid desaturases and analyzed their expression profiles in Gossypium raimondii under low temperature (Liu et al. (springeropen.com)
We found that of S. lappa extract reduced the expression of genes related to allergy metabolism in Nc/Nga mice. (molcells.org)
This study aims at integrating two gene expression profile datasets and verifying hub genes and pathways involved in TAD as well as exploring potential molecular mechanisms. (hindawi.com)
The two expression profile datasets were integrated and we found out coexpression of differentially expressed genes (DEGs) using bioinformatics methods. (hindawi.com)
The gene ontology and pathway enrichment of DEGs were performed by DAVID and Kyoto Encyclopedia of Genes and Genomes online analyses, respectively. (hindawi.com)
With the development of the gene expression profile, comparisons of differentially expressed genes that participate in the regulation of pathophysiological conditions in pathological tissue and normal tissue were available and convenient, and mRNAs gene expression profiles have been carried out in many diseases including TAD [ 6 ]. (hindawi.com)
Although high-throughput sequencing technologies have provided many diverse expressed genes, different expression profiles in TAD provided various results and no reliable results have been identified up to now [ 6 - 8 ]. (hindawi.com)
When compared with historic strains, recent isolates showed increased expression of flagellar genes and genes involved in lipopolysaccharide biosynthesis and decreased expression of polysaccharide capsule genes. (cdc.gov)
Recently, we have shown that, besides their effect on genome structure and stability, ISs can affect expression profiles of neighboring genes by IS element-specific promoters ( 21 ). (cdc.gov)
Based on differentially expressed genes, possible mechanisms of SWCNT-associated apoptosis resistance and oncogenesis were identified, which included activation of pAkt/p53/Bcl-2 signaling axis, increased gene expression of Ras family for cell cycle control, Dsh-mediated Notch 1, and downregulation of apoptotic genes BAX and Noxa. (cdc.gov)
As the sequencing and gene annotation projects of entire genomes of many species are headed towards completion (see, e.g. [13] ), massive mapping efforts in biology are now focused on how the genes interact. (lu.se)
Microarrays are one such tool that allows for the study of expression of thousands of genes simultaneously. (lu.se)
By monitoring microbial gene expression, one can predict the functions of uncharacterized genes, probe the physiologic adaptations made under various environmental conditions, identify virulence-associated genes, and test the effects of drugs. (medscape.com)
Genomics refers to the study of the genome as a whole, including single genes and the interaction of multiple loci and the environment. (cdc.gov)
Transposable elements have the unique ability to move within our DNA, causing or reversing mutations, altering genes, and even affecting the size of our genome. (lu.se)
These elements appear to influence the expression of both protein-coding genes and non-coding transcripts in the human brain through various mechanisms," says Raquel Garza. (lu.se)

Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. (nih.gov)
We aimed to study whole genomic lncRNA expression patterns in colorectal adenoma-carcinoma transition and to analyze the underlying functional interactions of aberrantly expressed lncRNAs. (biomedcentral.com)
In 2012, the CCLE collaborators took a deep dive into the genomic features and drug sensitivities of these cells, cataloging gene expression, chromosomal copy number, and targeted gene sequencing data from all 947 lines and a number of drug-response profiles. (broadinstitute.org)
These analyses include gene prediction, automated genomic annotation and genome comparison/alignment. (uni-hamburg.de)
On the basis of these observations, we hypothesized that strains with different genomic organization should display altered global transcriptomic and, consequently, proteomic profiles, and thereby genome rearrangements might contribute to strain variation and adaptation. (cdc.gov)
To do this, we will perform genome-wide siRNA screens on MITF-high and -low melanoma cells in combination with genomic analysis and suitable functional assays. (lu.se)

Polysome profiling reveals translational control of gene expression in the human malaria parasite Plasmodium falciparum. (stowers.org)

With the ongoing developments of high throughput sequencing machines and advancement of modern bioinformatics tools at unprecedented pace, the target goal of sequencing individual genomes of living organism at a cost of $1,000 each is seemed to be realistically feasible in the near future. (springer.com)

Background Genome range expression profiling of human being tumor samples is likely to yield improved malignancy treatment decisions. (cell-metabolism.com)
Caboux E, Paciencia M, Durand G, Robinot N, Wozniak MB, Galateau-Salle F, Byrnes G, Hainaut P, Le Calvez-Kelm F. Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples. (who.int)

Several independent high-throughput methods for differential gene expression (including SAGE and differential display) may enable function annotation of sequenced genomes [ 2 ] . (medscape.com)

In the context of cancer, gene expression profiling has been used to more accurately classify tumors. (wikipedia.org)
Presented below are ways that gene expression profiling has been used to more precisely classify tumors into subgroups, often with clinical effect. (wikipedia.org)
In breast cancer, manifestation profiles can easily discriminate between ER-negative and ER-positive tumors, which have very different medical behavior. (cell-metabolism.com)
The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. (nih.gov)
In line with aberrant expression of certain lncRNAs in tumors, the expression of miRNA and mRNA targets showed systematic alterations. (biomedcentral.com)
With rapidly evolving clinical applications in sequencing of the human genome as well as the genomes of tumors, the traditional anatomic descriptions of cancer types will be supplemented by molecular classification based on tumor genetic aberrations. (cdc.gov)

In this study, we compared microRNA profile in exosomes in 5 MHFMD and 5 ESHFMD as well as in 5 healthy children. (biomedcentral.com)

Here we report genome sequences and analyses of 44 diploid potatoes, as well as 2 species in the Etuberosum section. (nature.com)
In a compared analyses of ruptured vs unruptured aneurysms, a different expression was also detected regarding gene coding the tissue inhibitor of matrix metalloproteinases 3 (TIMP-3), which appeared markedly downregulated in unruptured aneurysms, where its expression in unruptured aneurysms was similar to that observed in controls. (unicatt.it)
Expression of a subset of candidates was verified by qRT-PCR and in situ hybridization (ISH) analyses. (biomedcentral.com)
Subsequent RNA sequence analysis and liquid chromatography with mass tandem spectrometry analyses showed that these variations translated into discretely separated transcriptomic and proteomic profiles. (cdc.gov)

The level of fluorescence at a particular spot provides quantitative information about the expression of the particular gene corresponding to the spotted cDNA sequence. (wikipedia.org)
This thematic series of companion papers constitutes the initial exploration of the genome biology of the waterflea (Daphnia) building on the first complete crustacean genome sequence. (biomedcentral.com)
Sequence analysis of the Daphnia pulex genome holds some surprises that could not have been anticipated from what was learned so far from other arthropod genomes. (biomedcentral.com)
Simple sequence repeats (SSRs) are highly variable features of all genomes. (biomedcentral.com)
For the future direction, we need the in-depth genome sequence information and analysis for most of the mammals, including human to fully understand genome variation of economic traits, genetic susceptibility to diseases, and pharmacogenomics of drug response. (springer.com)
A multi-center research team has now greatly augmented this cancer research resource by incorporating new cell lines and adding new data spanning the molecular spectrum from sequence to expression to protein. (broadinstitute.org)
The widely used CRISPR-Cas9 gene-editing technology has enabled researchers to alter genome sequence or gene expression with great precision, says JAX Assistant Professor Albert Cheng, Ph.D., first and co-corresponding author of a paper published in Cell Research . (jax.org)
For example, it can be fused to domains that activate or repress gene expression, allowing researchers to increase or decrease gene expression at will without changing the actual sequence. (jax.org)
Many diseases involve variations in gene expression rather than genetic sequence. (jax.org)
genome informatics focuses on the development and application of algorithms and software for analysis of large sets of data, e.g. sequence sets and transcriptome data. (uni-hamburg.de)
200 copies of insertion sequence 481 (IS481) in its genome ( 14 ). (cdc.gov)
As of August 10, 2000, draft sequence was available for 87% of the human genome (https://www.ncbi.nlm.nih.gov/genome/seq/), and at least 39 prokaryotic genomes, including those of more than a dozen human pathogens, had been completely sequenced https://www.tigr.org/tdb/mdb/mdbcomplete.html). (medscape.com)
Hall J. The Ataxia-telangiectasia mutated gene and breast cancer: gene expression profiles and sequence variants. (medlineplus.gov)

Reinventing potato from a clonally propagated tetraploid to a true seed-propagated diploid has the potential to considerably accelerate genetic improvement, and would enable the genome design of a crop that has been highly recalcitrant to the use of molecular breeding and genomics approaches 3 , 6 , 7 . (nature.com)
The unique pattern of gene expression for a given cell or tissue is referred to as its molecular signature. (wikipedia.org)
Current work includes in vitro profiling of human pulmonary artery endothelial cells with heterogeneous PAH-associated molecular defects in order to investigate molecular mechanisms that can exploited therapeutically. (nih.gov)
Dr. Lo and colleagues believe that most of these PanIN lesions would not have been amenable to other gene expression methodologies and that the PanIN data collected using the HTG EdgeSeq technology will contribute to a better understanding of the molecular pathways that underlie pancreatic cancer. (genomeweb.com)
To understand the molecular mechanisms underlying the failure of parthenogenesis at early stages of development, we performed global gene expression profiling and functional analysis of parthenogenetic blastocysts in comparison with those of blastocysts from normally fertilized embryos. (prinsesmaximacentrum.nl)
Profiling circRNAs by integrating their expression amongst totally different samples thus offers molecular foundation for additional practical examine of circRNAs and their potential software in clinic. (matticklab.com)
This study provides a comprehensive genome-wide resource for the functional exploration of molecular, cellular, and epigenetic regulation at the top of the hematopoietic hierarchy. (lu.se)
Here, we further examined the gene expression profile by using genome microarrays to profile molecular mechanisms of SWCNT oncogenesis. (cdc.gov)
Association between clinical expression and molecular heterogeneity in ß-thalassemia Tunisian patients. (cdc.gov)
Similarly, by using host gene microarrays, one can explore host response at the level of gene expression and provide a molecular description of the events that follow infection. (medscape.com)
His interests include Bordetella molecular pathogenesis and gene expression bioinformatics. (medscape.com)

Abstract Targeted metagenomics using strand-specific libraries with target enrichment is a sensitive, generalized approach to pathogen sequencing and transcriptome profiling. (ox.ac.uk)
Recent technological advances have enabled massively parallel chromatin profiling with scATAC-seq (single-cell assay for transposase accessible chromatin by sequencing). (nature.com)
Here we present ATAC with select antigen profiling by sequencing (ASAP-seq), a tool to simultaneously profile accessible chromatin and protein levels. (nature.com)
Due to lowering costs, RNA-Sequencing is becoming more common as a method for cancer gene expression profiling. (wikipedia.org)
The completion of the first human genome drafts (Yamey 2000 ) was just a start of the modern DNA sequencing era which resulted in further invention, improved development toward new advanced strategies of high-throughput DNA sequencing, so called the " high-throughput next generation sequencing " (HT-NGS). (springer.com)
During this period, tremendous success has been achieved in the fields of decoding of human genome, technological advancement of new era of human genome applications, toward personalized genomes and discovery of rare variants, leveraging genome sequencing to impact on cancer researches and mammalian evolution and population structure. (springer.com)
Using advanced sequencing technologies and a set of specialized bioinformatics tools, created by PhD student Raquel Garza, the researchers successfully detected the activity of LINE-1 elements and were able to dig into their functions and epigenetic profiles. (lu.se)

The long non-coding RNA expression profiles of stable angina pectoris were established from the results of the long non-coding RNA gene chip. (ijpsonline.com)
The long non-coding RNA expression profile of stable angina pectoris was established by analysing the long non-coding RNAs gene-chip. (ijpsonline.com)

LncRNA expression levels of colonic biopsy samples (20 CRCs, 20 adenomas (Ad), 20 healthy controls (N)) were analyzed with Human Transcriptome Array (HTA) 2.0. (biomedcentral.com)

In in vitro experiment using HaCaT cells, we found that the S. lappa components, including alantolactone, caryophyllene, costic acid, costunolide and dehydrocostus lactone significantly decreased the expression of PI3Kca but not IL20Rβ in vitro . (molcells.org)

Genome Biol , 11(12), R119. (mbl.edu)

However, genome-wide expression profiling of Formalin fixed, paraffin embedded samples have been challenging due to RNA degradation. (elsevierpure.com)
This online seminar focused on recent advances in gene expression profiling of challenging formalin-fixed, paraffin-embedded tissue samples for cancer research and clinical practice. (genomeweb.com)

Of note, similar gene expression patterns associated with metastatic behaviour of breast cancer tumor cells have also been found in breast cancer of dog, the most common tumor of the female dog. (wikipedia.org)
Results Derivation of DNBC-specific consistent expression indices (CEIs) We created a reference data set of DNBC from five previously published breast cancer cohorts that were all profiled on the same. (cell-metabolism.com)
Gleason score and prostate specific antigen) others such as gene expression profiling for breast cancer are used to predict response to therapy and guide treatment decisions. (cdc.gov)
A recent study of the disparity in breast cancer mortality between AA and EA women concluded that differences in mortality are driven by higher hazard rates of breast cancer death in AA women, irrespective of ER expression [9]. (cdc.gov)

Characterization of mRNA Expression and Endogenous RNA Profiles in Bladder Cancer Based on The Cancer Genome Atlas (TCGA) Database. (matticklab.com)
MATERIAL AND METHODS RNA profiles have been downloaded from The Cancer Genome Atlas (TCGA) database. (matticklab.com)

The National Human Genome Research Institute (NHGRI) has echoed this need through its vision for genomics research (Collins et al. (springer.com)
Year 2011 is celebrated as the 10th anniversary since the human genome was first sequenced ( www.nature.com/natureconferences/hg10years/index.html ). (springer.com)
Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotube s. (cdc.gov)
The challenge has been to determine what these elements do and how they affect human tissues, given their abundant and repetitive presence in the human genome. (lu.se)

The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. (nih.gov)

An extensive literature documenting physiological and ecological diversity make Daphnia an ideal model to study the genetic architecture of phenotypic variation in natural populations and the evolution of genome structure/function relationships in aquatic environments. (biomedcentral.com)
Genetic manipulations allowed analysis of changes in gene expression underlying pheromone signaling, cell cycle control, and polarized morphogenesis. (nih.gov)
Genetic alterations and altered expressions of mRNAs, lengthy non-coding RNAs (lncRNAs), and miRNAs have been proven to play necessary roles in the tumorigenesis of bladder most cancers . (matticklab.com)
These data, along with statistical models, allow us to see otherwise-hidden connections between genetic and epigenetic errors in cancer cells and changes in those cells' metabolic profiles," Li said. (broadinstitute.org)

Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension. (nih.gov)
Gene expression analysis of pancreatic intraepithelial neoplasia's (PanINs), the classical pancreatic cancer precursor, has been challenging because extracting and purifying RNA from pancreatic tissue is difficult. (genomeweb.com)
Comprehensive lncRNA-mRNA-miRNA co-expression pattern analysis was also performed. (biomedcentral.com)
Analysis of the profiles specified by two different MAPKs-Fus3p and Kss1p-revealed functional overlap of the filamentous growth and mating responses. (nih.gov)
In what follows we limit ourselves to the analysis of gene expression measurements obtained using microarrays with small spots of DNA fixed to glass slides. (lu.se)

The main emphasis is on supervised machine learning methods for classification and prediction of tumor gene expression profiles. (lu.se)

The information derived from gene expression profiling often helps in predicting the patient's clinical outcome. (wikipedia.org)
Host profiling might also identify gene expression signatures unique for each pathogen, thus providing a novel tool for diagnosis, prognosis, and clinical management of infectious disease. (medscape.com)

We demonstrated that global gene expression profiling of F1 and F2 clearly reflected a difference in their follicular status. (biomedcentral.com)

dCas9 can be fused to protein tags or the effector domains of transcription factors (proteins that bind DNA in promoter regions and simultaneously bind other regulatory proteins via effector domains, which can activate or repress transcription and thereby affect gene expression) to develop customized DNA binding proteins. (jax.org)

refine.bio: a resource of uniformly processed publicly available gene expression datasets. (refine.bio)
Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. (cancerindex.org)

Genome-wide expression profiling experiments were carried out using ABI high-density oligonucleotide microarrays in leukocytes from 25 POAG patients and 12 age-, ethnicity-, and sex-matched normal controls. (johnshopkins.edu)

Our findings provide insights into the alteration of potato genomes during the evolution of tuberization, and will enable genome design for new diploid hybrids. (nature.com)

Using such probes, one can obtain a fingerprint of the gene expression activity in a macroscopic sample. (lu.se)

The leading genome research centers and scientists have publicly recognized that these are the core enabling goals for the next decade genomics research. (springer.com)

Sixty-two bZIP-TFs in Chinese pear were identified, and their expression profiles were comprehensively analyzed under ABA, SA, and MeJa hormones, which respond to multiple abiotic stresses and fruit growth and development. (udl.cat)

This approach helped us to address these highly repetitive sequences, usually masked in standard bioinformatics pipelines, allowing us to accurately measure LINE-1 expression in each cell type found in our samples," explains Raquel Garza, co-first author of the study. (lu.se)

Mammalian parthenogenesis could not survive but aborted during mid-gestation, presumably because of lack of paternal gene expression. (prinsesmaximacentrum.nl)

Scope includes mutations and abnormal protein expression. (cancerindex.org)

Some studies compared the gene expression profiles between DF and SF around the time of follicular selection. (biomedcentral.com)

A new gene regulation and labeling platform dubbed "Casilio" can simultaneously execute distinct functions at multiple areas of the genome at the same time, expanding researchers' ability to study gene function and chromosome structure, Jackson Laboratory (JAX) researchers report. (jax.org)
Casilio 'orchestrates' variations throughout the genome, simultaneously and in high fidelity. (jax.org)

Furthermore, the effects of the evolution of a clonal reproduction strategy on potato genomes and the evolutionary mechanisms of tuberization are largely unexplored. (nature.com)

A subset of CRC-associated lncRNAs showed significantly differential expression in precancerous samples, raising the possibility of developing adenoma-specific markers for early detection of colonic lesions. (biomedcentral.com)
This atlas permits customers to look, browse, and obtain circRNAs with expression options in numerous cell sorts/tissues, together with illness samples. (matticklab.com)

Our data reveal the differential expression landscape of 493 transcription factors and 682 lncRNAs and highlight specific expression clusters operating in HSCs. (lu.se)

MiRNA targets of lncRNAs were predicted with miRCODE and lncBase v2 algorithms and miRNA expression was analyzed on miRNA3.0 Array data. (biomedcentral.com)

MicroRNAs (miRNAs) are an integral part of the post-transcriptional machinery of gene expression and have been implicated in the carcinogenic cascade. (cdc.gov)

Our study is the first, to our knowledge, that compares gene expression profiles (genoma-wide) in intracranial aneurysms. (unicatt.it)
Genome wide association study of thyroid hormone levels following challenge with porcine reproductive and respiratory syndrome virus. (usda.gov)
This study indicated that the exosomal miRNA from patients with different condition of HFMD express unique miRNA profiles. (biomedcentral.com)
Furthermore, a previous study indicated that gene order rearrangements associated with IS elements can alter gene expression profiles in B. pertussis ( 20 ). (cdc.gov)
thus, genomewide transcription profiling seems particularly appropriate for the study of this process. (medscape.com)

Gene expression also linked reduced expression of Xist to activation of X chromosome. (prinsesmaximacentrum.nl)
Its genome contains one genome copy from the S. uvarum parental genome and two heterozygous copies of the S. cerevisiae parental genome, with the exception of a monosomic S. cerevisiae chromosome III, where the sex-determining MAT locus is located. (frontiersin.org)

Long non-coding RNAs (lncRNAs) play a fundamental role in colorectal cancer (CRC) development, however, lncRNA expression profiles in CRC and its precancerous stages remain to be explored. (biomedcentral.com)
Based on our HTA results, a subset of literature-based CRC-associated lncRNAs showed remarkable expression changes already in precancerous colonic lesions. (biomedcentral.com)

Anatomy5

Organisms3

Diseases1

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes54

Disciplines and Occupations5

Technology, Industry, Agriculture1

Information Science9

Health Care4

Whole genome3

Methylation2

Microarray10

Biomarkers6

Genes39

Genomic6

Reveals1

Organism1

Tumor samples2

Annotation1

Tumors6

MicroRNA1

Analyses4

Sequence13

Molecular11

Sequencing7

Long non-coding RNA exp2

Transcriptome1

Vitro1

Biol1

Paraffin embedded2

Breast cancer4

Cancer Genom2

Human4

TCGA1

Genetic4

Analysis5

Methods1

Clinical2

Global gene expression1

Proteins1

Datasets2

Microarrays1

Hybrids1

Fingerprint1

Genomics1

Abiotic1

Sequences1

Mammalian1

Protein expression1

Compared the gene expression1

Simultaneously2

Evolutionary1

Samples2

Differential expression1

MiRNA expression1

MiRNAs1

Study5

Chromosome2

LncRNAs2