Genome biology and evolution. Medical search. Frequent questions

Of 1,107/225/1,141 rumen microbial genera/metagenome assembled uncultured genomes (RUGs)/genes identified from whole metagenomics sequencing, 194/14/337 had significant host genomic effects (heritabilities ranging from 0.13 to 0.61), revealing that substantial variation of the microbiome is under host genomic control. (nature.com)
We find that the potato genome substantially expanded its repertoire of disease-resistance genes when compared with closely related seed-propagated solanaceous crops, indicative of the effect of tuber-based propagation strategies on the evolution of the potato genome. (nature.com)
In addition, both protein-coding and microRNA genes related to reproduction exhibited evidence of rapid sequence evolution. (uniba.it)
Many of the genes reconstructed in this process come from numerous individual fragments dispersed across the micronuclear genome-with some even being inverted in their orientation. (icr.org)
The application of fluorescence in situ hybridization for the mapping of genes and sequences, as well as comparative analyses of genome homology by comparative genomic hybridization will be useful tools for understanding the genomic changes in relation to evolutionary processes such as speciation and adaptation to different environments. (karger.com)
We already knew that snakes lost some vision genes and eye structures during their evolution from lizards, but most were nonetheless retained. (eurekalert.org)
This study also shows convergent evolution between subterranean snakes and burrowing mammals with the loss of similar genes, especially those associated with bright-light and colour vision. (eurekalert.org)
G3, Genes/Genomes/Genetics. (usda.gov)
A new study led by members of Ann Tate's (Assistant Professor of Biological Sciences) lab found evidence that pleiotropy may slow down evolution of genes involved in immunity. (vanderbilt.edu)
The paper, titled "The effect of developmental pleiotropy on the evolution of insect immune genes," was published in Genome Biology and Evolution . (vanderbilt.edu)
Genes involved in development often are under purifying selection - that is, evolution is acting to keep things the same, which is common for important genes. (vanderbilt.edu)
In contrast, when co-evolution is occurring between a pathogen and its host, genes regulating immunity must be able to evolve or the pathogen could overwhelm the organism. (vanderbilt.edu)
The effect of developmental pleiotropy on the evolution of insect immune genes. (vanderbilt.edu)
However, not only are mutations hardly ever beneficial, but because genes are so widely interconnected in the genome, a mutation in one gene will have a downstream effect on many others, especially if it's in a gene involved in regulating other genes. (icr.org)
1 In an effort to further analyze the restraints of pleiotropy on the evolutionary model, the researchers focused on genes that produce proteins called transcription factors (TFs) which act like switches in the genome turning other genes on and off. (icr.org)
Our new findings demonstrate that almost every large cetacean species seems to have other positively selected genes in their genome. (senckenberg.de)
Wang SS* , Chen YH, Cao QH, Lou HQ* (2015) Long-Lasting Gene Conversion Shapes the Convergent Evolution of the Critical Methanogenesis Genes. (edu.hk)
Furthermore, a genome-wide comparison of selection rates between large and small-bodied baleen whales revealed a small set of conserved candidate genes with potential connections to cancer resistance. (lu.se)
The lack of shared positive selected genes between different large-bodied whale species supports a previously proposed convergent evolution of gigantism and hence cancer resistance in baleen whales. (lu.se)
We observed that M. avium isolates from different sources-human pulmonary infections, human disseminated infections, animals, and natural environments-are readily distinguished by their core and accessory genomes, by their patterns of horizontal gene transfer, and by numerous specific genes, including virulence factors. (cdc.gov)

It covers research on the interface between evolutionary biology and genomics. (wikipedia.org)
These data confirm that the mitochondrial genome originated from a eubacterial (specifically α-proteobacterial) ancestor but raise questions about the evolutionary antecedents of the mitochondrial proteome. (biomedcentral.com)
Furthermore, the effects of the evolution of a clonal reproduction strategy on potato genomes and the evolutionary mechanisms of tuberization are largely unexplored. (nature.com)
Genomes of Africans contain mixtures of multiple ancestries, each of which has experienced different evolutionary histories. (news-medical.net)
In the article 'Evolutionary Genetics and Admixture in African Populations,' researchers from two institutes - Georgia Institute of Technology and Mediclinic Precise Southern Africa - reviewed how multiple demographic events have shaped African genomes over time (Pfennig, et al. (news-medical.net)
Co-funded by FAPESP SPRINT (call 3/2019), awards have been made across the Faculties of Science, Engineering & Design, and Humanities & Social Sciences, and cover a range of topics that reflect our strong research links with universities in Brazil, including water, sustainable technologies, evolutionary biology and genetics, and foreign policy. (bath.ac.uk)
This project addresses a fundamental conundrum in evolutionary biology: why do populations harbor abundant genetic variation, despite the expectation that natural selection should remove variation, especially for traits tied to survival and reproduction? (bath.ac.uk)
Evolutionary significance of genome duplication. (uoguelph.ca)
This cytogenetic diversity offers the opportunity to perform cytotaxonomic and phylogenetic studies, as well as structural, evolutionary, and functional analyses of the genome. (karger.com)
8. Peruvian Genome Project: A study in Pre and Post Peruvian Inca Demography and their Evolutionary Dynamics. (upenn.edu)
The tools include identifying significant local alignments (utilizing both two-way and three-way alignments), dividing the set of alignments into connected components (signifying repeat families), computing evolutionary distance between repeat fanfily members, constructing minimum spanning trees from the connected components, and visualizing the evolution of the repeat families. (aaai.org)
In this study the flow cytometry technique was used to uncover the genome size and GC contents of 46 Nicotiana species and we compared the genomic changes associated with the hybridization events along evolutionary time scale. (scielo.br)
Evolutionary consequences associated with hybridization events have been studied at various levels such as chromosomal rearrangements, repetitive DNA sequence evolution, genome size change, and diploidization ( Hegarty and Hiscock, 2008 HEGARTY, M.J. and HISCOCK, S.J., 2008. (scielo.br)
The researchers reconstructed evolutionary patterns of genome size across the whole fern phylogeny. (phys.org)
Using phylogenetic generalized least square methods, the researchers determined correlations between chromosome number and genome size, species diversity and evolutionary rates of their transformation. (phys.org)
Their genomes have been used to investigate their complex evolutionary history and to decipher the molecular mechanisms that allowed them to reach these dimensions. (lu.se)
Although there are some new evolutionary arguments discussed, the article offers the usual hype that "evolution has been proven" and the creationists should just give up and go home. (creation.com)
On the Master's programme in Evolutionary Biology you will learn how to unravel the history of life by examining diversification, adaptation, and how the evolutionary process itself evolves. (lu.se)
You will acquire conceptual and methodological skills in molecular and genome evolution, evolutionary developmental biology, and evolutionary ecology. (lu.se)
Our teaching promotes an active, inquiry-based learning that is integrated with our Department's world-leading research on the evolutionary biology of microbes, plants, and animals. (lu.se)
Pardis Sabeti, MD, DPhil, is a member of the Broad Institute of Harvard and Massachusetts Institute of Technology (MIT), and a professor at the Center for Systems Biology and the Department of Organismic and Evolutionary Biology at Harvard University. (medscape.com)
Were you already starting to get into the whole selection, mutation, and evolutionary biology by then? (medscape.com)
Software and Databases for Molecular Evolutionary Biology. (who.int)
The aim of this review is to provide scientific information for better understanding of the evolutionary biology, molecular epidemiology, pathogenesis, diagnosis, and prevention of Lassa fever in Nigeria and other endemic regions worldwide, which can lead to improved control efforts and reduce morbidity and mortality from recurrent epidemics. (bvsalud.org)

To address these longstanding problems we combine population genetics and population genomics, functional genetics, transcriptomics, physiology, and experimental evolution and apply them to natural and laboratory populations of D. melanogaster that are phenotypically differentiated for fitness-related traits. (unifr.ch)

Novel microbial species in the rumen have recently been identified using metagenome-assembled genomes generated from whole metagenomic sequence data of microbial DNA from rumen samples 8 , 34 , but how their abundances are shaped by host genomics is still unknown. (nature.com)
Reinventing potato from a clonally propagated tetraploid to a true seed-propagated diploid has the potential to considerably accelerate genetic improvement, and would enable the genome design of a crop that has been highly recalcitrant to the use of molecular breeding and genomics approaches 3 , 6 , 7 . (nature.com)
To unravel this mystery, researchers from the Senckenberg Biodiversity and Climate Research Centre (SBiK-F), the Hessian LOEWE Centre for Translational Biodiversity Genomics (TBG) and the Universities of Frankfurt am Main and Lund, Sweden, analysed the genome of the pygmy right whale. (senckenberg.de)
The leading genome research centers and scientists have publicly recognized that these are the core enabling goals for the next decade genomics research. (springer.com)
The National Human Genome Research Institute (NHGRI) has echoed this need through its vision for genomics research (Collins et al. (springer.com)
The Rhodoexplorer Platform for Red Algal Genomics and Whole Genome Assemblies for Several Gracilaria Species. (sb-roscoff.fr)
Here, we used comparative genomics to illuminate key aspects of MAC biology. (cdc.gov)
The CLC Genomics Workbench (CLC bio, Aarhus, Denmark) and Lasergene NextGen (DNASTAR, Madison, WI, USA) were used to analyze and assemble raw sequence reads. (cdc.gov)

2017) Examples of How FDA Has Used Whole Genome Sequencing of Foodborne Pathogens For Regulatory Purposes. (who.int)

Sequencing has also shown that mitochondrial genomes have, to variable extents, undergone a streamlining process ("reductive evolution" [ 20 ]), leading to a marked loss of coding capacity compared to that of their closest eubacterial relatives. (biomedcentral.com)
The team looked at structural changes in the genomes of cancer samples using advanced DNA sequencing technologies. (biologynews.net)
Genome sequencing of normal cells reveals developmental lineages and mutational processes. (genomeweb.com)
Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. (genomeweb.com)
Exploring genetic variation in the tomato ( Solanum section Lycopersicon) clade by whole-genome sequencing. (genomeweb.com)
Variant detection sensitivity and biases in whole genome and exome sequencing. (genomeweb.com)
The Marmoset Genome Sequencing and Analysis Consortium. (genomeweb.com)
International Wheat Genome Sequencing Consortium (IWGSC). (genomeweb.com)
With the ongoing developments of high throughput sequencing machines and advancement of modern bioinformatics tools at unprecedented pace, the target goal of sequencing individual genomes of living organism at a cost of $1,000 each is seemed to be realistically feasible in the near future. (springer.com)
The completion of the first human genome drafts (Yamey 2000 ) was just a start of the modern DNA sequencing era which resulted in further invention, improved development toward new advanced strategies of high-throughput DNA sequencing, so called the " high-throughput next generation sequencing " (HT-NGS). (springer.com)
During this period, tremendous success has been achieved in the fields of decoding of human genome, technological advancement of new era of human genome applications, toward personalized genomes and discovery of rare variants, leveraging genome sequencing to impact on cancer researches and mammalian evolution and population structure. (springer.com)
Front and center in the article is the report on the recent sequencing of the chimpanzee genome and the 96% similarity to human DNA. (creation.com)
In this paper we report on genome sequencing of 154 SARS-CoV-2 samples between June and July 2021 (Summer outbreak) in the Bailiwick of Jersey, a UK channel island. (medrxiv.org)
Since the publication of the first sequence at the beginning of 2020, viral genome sequencing has become a powerful tool to study the SARS-CoV-2 genome 1 , 4 . (medrxiv.org)
This material demonstrates how whole genome sequencing can be used to detect SARS-CoV-2 variants and inform public health response. (cdc.gov)
This study examined the added value of whole genome sequencing (WGS) for investigating a non-point source outbreak of Salmonella ser. (who.int)
2016) Whole genome sequencing of Salmonella Typhimurium illuminates distinct outbreaks caused by an endemic multi-locus variable number tandem repeat analysis type in Australia, 2014. (who.int)
2016) Expert opinion on whole genome sequencing for public health surveillance. (who.int)
2016) Identification of Salmonella for public health surveillance using whole genome sequencing. (who.int)
7) Octavia S, Wang Q, Tanaka MM, Kaur S, Sintchenko V, Lan R. (2015) Delineating community outbreaks of Salmonella enterica serovar Typhimurium by use of whole-genome sequencing: insights into genomic variability within an outbreak. (who.int)
10) Carleton HA, Gerner-Smidt P. (2016) Whole-genome sequencing is taking over foodborne disease surveillance. (who.int)
Implementation of Nationwide Real-Time Whole-Genome Sequencing to Enhance Listeriosis Outbreak Detection and Investigation. (cdc.gov)
DNA libraries for next-generation sequencing were prepared directly from RNA extracted from serum, and the amplified libraries were sequenced by using the Ion Torrent Personal Genome Machine (Life Technologies, Grand Island, NY, USA). (cdc.gov)

Genome Biology and Evolution is a monthly peer-reviewed open access scientific journal published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. (wikipedia.org)
Society for Molecular Biology and Evolution. (upenn.edu)
Before the advent of modern molecular biology, scientists defined a gene as a single unit of inheritance. (icr.org)
Molecular biology and structure of a novel penaeid shrimp densovirus elucidate convergent parvoviral host capsid evolution. (cdc.gov)
Dr. Matzinger received a BA in Biophysics, Biochemistry, and Molecular Biology from Whitman College and her doctorate in Microbiology from the University of California, Davis. (cdc.gov)
a deep knowledge and understanding of how plants function at different levels of organization, from molecular biology to ecophysiological level, including: the structure and properties of cells, the life processes and their regulation, genome structure, function and evolution, and plant development and reproduction systems. (lu.se)
Chemistry, or MOBA03 Molecular Biology 15 credits, are required. (lu.se)

Causes and consequences of linkage disequilibrium among transposable elements within eukaryotic genomes. (sb-roscoff.fr)
is the invader`s genome being invaded by transposable elements? (univ-lyon1.fr)

b Comparison of 2275 gene pairs from the terminal 150 Mb of short chromosome arms from A and B genomes. (biomedcentral.com)
As it turns out, the germline genome of the micronucleus is fragmented into over 225,000 precursor DNA segments that are massively and precisely rearranged (unscrambled) during the construction of the new macronucleus and its nanochromosomes (most of which contain only one gene each). (icr.org)
In the study, researchers from Brown University, the Universidad Nacional Autónoma de México, and the University of California-Merced analyzed how the resulting gene flow between modern humans redistributed archaic ancestry in admixed genomes. (news-medical.net)
Examining this question, the project aims to assess patterns of gene and genome evolution within and among natural populations by studying the enormous genetic diversity of a social microbe living as single celled predators of bacteria before producing a multicellular fruiting body. (bath.ac.uk)
Working with researchers at Universidade Federal de São Carlo, the project will assemble genome sequences from DNA sequence data and then use these assemblies to examine patterns of gene gain and loss, how signatures of selection vary based on gene properties and patterns of gene sequence variability in relation to geography (including climatic variables). (bath.ac.uk)
The importance of genetic diversity (mutation, gene flow, drift, heritability) to adaptive evolution is widely recognized, but it is less clear whether and how it affects ecological function and viability of populations. (uoguelph.ca)
The nearly complete platypus genome assembly has anchored almost the entire genome onto chromosomes, markedly improving the genome continuity and gene annotation. (edu.au)
For this research, published in Genome Biology and Evolution , scientists generated new gene-sequence data for the dark-spined blind snake ( Anilios bicolor ) and the prong-snouted blind snake ( Anilios bituberculatus ), both of which are common across southern Australia. (eurekalert.org)
Sometimes called the 'guardian of the genome,' p53 is a tumor suppressor gene that, when neutralized, plays a critical role in the development of many types of tumors. (mdanderson.org)
In this new research report, the authors state, 'Many studies have provided evidence for the ability of pleiotropy to constrain gene evolution. (icr.org)
The availability of this extended region of contiguous sequence has allowed us to analyze the nature and prevalence of repetitive sequences in the genome of a eukaryotic organism with a high gene density. (aaai.org)
Fontsere C, de Manuel M, Marques-Bonet T, Kuhlwilm M. Admixture in mammals and how to understand its functional implications: on the abundance of gene flow in mammalian species, its impact on the genome, and roads into a functional understanding. (upf.edu)
More than half (23 of 39) of the articles represent epidemiologic studies including candidate gene and genome-wide association studies (GWAS) examining genetic effect modification on disease risk. (cdc.gov)
Here, we leveraged a unique collection of genomes to characterize MAC population structure, gene content, and within-host strain dynamics in unprecedented detail. (cdc.gov)

The second proposition is that attrition of telomeres - the specialized genome sequences at the tips of chromosomes - causes genome instability at cell division. (biologynews.net)
The authors of the report state that a 'notable feature arising from this radical genome architecture is that a single MDS [macronucleus destined sequence] in the MIC may contribute to multiple, distinct MAC [macronucleus] chromosomes. (icr.org)
2014. The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome with 16,000 Tiny Chromosomes. (icr.org)
They used the parameters linked to the amount of DNA and its packaging in chromosomes, such as genome size, chromosome number , and average DNA amount per chromosome into a time-scaled phylogenetic framework, to elucidate the dynamics of genome space evolution in ferns. (phys.org)

Wang SS *, Chen YH (2018) Phylogenomic analysis demonstrates a pattern of rare and long-lasting concerted evolution in prokaryotes. (edu.hk)

Here we report genome sequences and analyses of 44 diploid potatoes, as well as 2 species in the Etuberosum section. (nature.com)
Is there any empirical support for that different part of a genome of some species have different mutation rates, that would give us empirical support for the possibility that some species under evolution have the ability to adjust (by NS itself or even epigenetics) the mutation rate of specific parts of the genome? (stackexchange.com)
Here, we report 25 newly sequenced genomes from museum specimens of the model organism Drosophila melanogaster , including the oldest extant specimens of this species. (biorxiv.org)
By comparing historical samples ranging from the early 1800s to 1933 against modern day genomes, we document evolution across thousands of generations, including time periods that encompass the species' initial occupation of northern Europe and an era of rapidly increasing human activity. (biorxiv.org)
We have explored these issues through studies on endangered species, effective population size, metapopulation dynamics, the effects of drift on mating system evolution, inbreeding depression, and the mechanisms by which hybridization causes extirpation of rare species. (uoguelph.ca)
Together with our echidna sequence, the genomes of the two species allow us to detect the ancestral and lineage-specific genomic changes that shape both monotreme and mammalian evolution. (edu.au)
Alissa Williams, postdoctoral researcher, and Thi Ngo, lab alumna, equally contributed to the new paper studying the evolution of immunity in Drosophila species. (vanderbilt.edu)
Not all species have the same amount of pleiotropy within their genome. (vanderbilt.edu)
The tetraploid species in genus Nicotiana including section Polydiclae , Repandae , Nicotiana , Rustica and Sauveolentes revealed both up and downsizing in their genome sizes when compared to the sum of genomes of their ancestral species. (scielo.br)
The genome sizes of three homoploid hybrids were found near their ancestral species. (scielo.br)
Hybridization and genome size evolution: timing and magnitude of nuclear DNA content increases in Helianthus homoploid hybrid species. (scielo.br)
The ups and downs of genome size evolution in polyploid species of Nicotiana (Solanaceae). (scielo.br)
Ferns are the second most species-rich lineages of land plants and highly suitable to test the association between genome diversity and lineage diversification. (phys.org)
For the first time, our results recovered evidence for a close link between the dynamics of genome evolution and species diversity in ferns," said Tao Fujiwara, first author of the study. (phys.org)
Tao Fujiwara et al, Evolution of genome space occupation in ferns: linking genome diversity and species richness, Annals of Botany (2021). (phys.org)
Results: Here, we present a first de novo genome of the species and test its potential in phylogenomics and cancer research. (lu.se)
To do so, we constructed a multi-species coalescent tree from fragments of a whole-genome alignment and quantified the amount of introgression in the early evolution of rorquals. (lu.se)
The student will have access to hundreds of genomes from both endangered and non-endangered bird species. (lu.se)

SARS-CoV-2 has spread with the evolution of its viral genome since its emergence in late 2019. (medrxiv.org)

This placement makes the pygmy right whale genome an interesting target to update the complex phylogenetic past. (lu.se)
This placement makes the pygmy right whale genome an interesting target to update the complex phylogenetic past of baleen whales, because it splits up an otherwise long branch that leads to the radiation of rorquals. (lu.se)

Advances in Computational Biology / Bioinfo4Women. (mpg.de)

Cancer is typically viewed as a gradual evolution, taking years to accumulate the multiple mutations required to drive the cancer's aggressive growth. (biologynews.net)
This produces a fractured genome riddled with mutations which may well have taken a considerable leap along the road to cancer. (biologynews.net)
I'm only interested in the mutations happening in the scope of the lifetime of a individual organism, I'm not interested in whether the mutations persisted under NS are equally distributed over the genome. (stackexchange.com)
A new study reconfirms mutations are a major roadblock for evolution. (icr.org)
Pervasive pleiotropy is a major problem for the concept of evolution in which mutations are thought to provide the genetic fodder for new beneficial traits to evolve. (icr.org)
SARS-CoV-2 genome variation study enables a comprehensive understanding of virus transmission, rate of mutations, track evolution, development of vaccines, and treatment 5 . (medrxiv.org)
This project aims to employ different cutting-edge bioinformatics techniques to predict deleterious scores of mutations across a comprehensive dataset of avian genomes, representing a broad swath of the avian phylogenetic tree, and compare their accuracy. (lu.se)

2 The ciliate Oxytricha trifallax has two different genomes contained in separate nuclei. (icr.org)

Infectious hypodermal and hematopoietic necrosis virus (IHHNV)-related sequences in the genome of the black tiger prawn Penaeus monodon from Africa and Australia. (cdc.gov)

Is the amitochondrial condition in these organisms a secondary adaptation or is it evolutionarily primitive - or, in other words, did any organisms diverge from the main line of eukaryotic evolution before the advent of mitochondria? (biomedcentral.com)
Wang SS, Luo H (2021) Dating Alphaproteobacteria evolution with eukaryotic fossils. (edu.hk)

Computational studies and Bioinformatics is an interdisciplinary field that progresses and applies computational methods to explore biological data collections such as protein samples, cell populations and genetic sequences for newer predictions or find out new Biology. (wikicfp.com)

A number of specific and general insights into mitochondrial genome evolution follow from these data. (biomedcentral.com)

A first analysis has permitted comparison with the genomes of apes and Old World monkeys and the identification of specific features that might contribute to the unique biology of this diminutive primate, including genetic changes that may influence body size, frequent twinning and chimerism. (uniba.it)
One avenue for better understanding the genetic architecture of African genomes is the study of ancient DNA: 'Going forward, analysis of ancient DNA is expected to become much more common. (news-medical.net)
Coming from computer science with an interest in genetic programming (a process emulating evolution) I'm curious about whether the rate of mutation is homogeneous across the whole genome, or if some parts of the genome differ in the rate of mutation. (stackexchange.com)
The researchers say it would be extremely unlikely for such genetic deficiencies to have been reversed through evolution. (eurekalert.org)
Once again, as with other modern genetic studies in pleiotropy, evolution came up wanting. (icr.org)
For the future direction, we need the in-depth genome sequence information and analysis for most of the mammals, including human to fully understand genome variation of economic traits, genetic susceptibility to diseases, and pharmacogenomics of drug response. (springer.com)
The student will contribute to not only refining the technical application of these methods but also addressing fundamental biological questions regarding the evolution of genetic load. (lu.se)
This project offers a unique opportunity to delve into the dynamics of genetic variation and its implications for conservation biology, providing valuable contributions to the field and paving the way for future research in biodiversity conservation. (lu.se)
Genetic changes in the viral genome may have enabled the virus to adapt to humans. (bvsalud.org)
Ongoing research into the genetic and ecological factors that drive the evolution of Lassa virus is necessary to reduce the impacts of Lassa fever. (bvsalud.org)

Year 2011 is celebrated as the 10th anniversary since the human genome was first sequenced ( www.nature.com/natureconferences/hg10years/index.html ). (springer.com)
In addition to the human genome, we are seeing the emergence of other "omic" data (e.g., transcriptomics, epigenomics, and proteomics) in epidemiologic research. (cdc.gov)

Although genomic changes associated with these events has been studied at various levels but the genome size and GC content variation is less understood because of absence of sufficient genomic data. (scielo.br)

They used data from the 1000 Genomes Project that were acquired from several admixed populations, including Colombians from Medellin, individuals with Mexican Ancestry from Los Angeles, Peruvians from Lima, and Puerto Ricans from Puerto Rico. (news-medical.net)
degree in which I investigated the biology of submerged aquatic plants and focused my interests on the ecology of small, isolated plant populations. (uoguelph.ca)

Evolution of genome size in Drosophila. (univ-lyon1.fr)

The imminent availability of the complete genome of Rhodnius prolixus also opens new perspectives for understanding the evolution and genome expression of triatomines. (karger.com)
Complete genome sequence of the Arcobacter canalis type strain LMG 29148. (usda.gov)
Complete genome sequence of the hippuricase-positive Campylobacter avium type strain LMG 24591. (usda.gov)
Complete genome sequences of Campylobacter hyointestinalis subsp. (usda.gov)
ClustalW ( www.ebi.ac.uk/Tools/msa/clustalw2/ ) was used to align the complete genome sequences with a variety of CHIKV sequences, representing the 3 genotypes, from GenBank. (cdc.gov)
Phylogenetic tree derived by neighbor-joining methods (1,000 bootstrap replications) using complete genome sequences of chikungunya viruses obtained from GenBank. (cdc.gov)

2016. Complex Patterns of Association between Pleiotropy with Transcription Factor Evolution. (icr.org)

Two recent studies published in Genome Biology and Evolution examine patterns of admixture in two different regions of the world-;Africa and the Americas-;revealing how this process has shaped the genomes of modern humans. (news-medical.net)

Here we assemble 44 high-quality diploid potato genomes from 24 wild and 20 cultivated accessions that are representative of Solanum section Petota , the tuber-bearing clade, as well as 2 genomes from the neighbouring section, Etuberosum . (nature.com)

This paper summarizes the chromosomal variability of the subfamily and how it may reveal aspects of genome evolution in this group. (karger.com)
van der Valk T, Díez-Del-Molino D, Marques-Bonet T, Guschanski K, Dalén L. Historical genomes reveal the genomic consequences of recent population decline. (upf.edu)

Publisher Correction: The reference genome of Miscanthus floridulus illuminates the evolution of Saccharinae. (bvsalud.org)

The 5' terminus genome encodes nonstructural proteins (nsps) that are involved in the process of the virus infection cycle. (medrxiv.org)

Primate epigenetic evolution: An analysis of CpG island evolution in the human, chimpanzee, gibbon, and rhesus monkey genomes. (upenn.edu)

PLOS Biology provides an Open Access platform to showcase your best research and commentary across all areas of biological science. (plos.org)

[17] A secondary endosymbiosis event involving an ancestral red alga and a heterotrophic eukaryote resulted in the evolution and diversification of several other photosynthetic lineages such as Cryptophyta , Haptophyta , Stramenopiles (or Heterokontophyta) , and Alveolata . (wikipedia.org)
Here we generate and analyse reference genomes of the platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus), which represent the only two extant monotreme lineages. (edu.au)
They identified a point in the evolution of the rorquals where their common ancestor split into three lineages at the same time. (senckenberg.de)
In a study published in Annals of Botany , researchers from the Xishuangbanna Tropical Botanical Garden (XTBG) of the Chinese Academy of Sciences provided strong support to the hypothesis that the diversification of plant lineages has been shaped by the dynamics of their genome evolution. (phys.org)

One-cell creatures called ciliates are expanding our knowledge of genome dynamics and complexity. (icr.org)

This genome sequence for a New World monkey enables increased power for comparative analyses among available primate genomes and facilitates biomedical research application. (uniba.it)
In both cases we are using comparative analyses, manipulative experiments and multi-generational selection studies to understand the evolution of these traits. (uoguelph.ca)
A recent article from the Washington Post had the headline: "New Analyses Bolster Central Tenets of Evolution Theory. (creation.com)

So far, relatively few studies have examined the genome evolution and diversity of wild and cultivated landrace potatoes, which limits the application of their diversity in potato breeding. (nature.com)
Add in some messiness in cutting out the specific sequences, and you have a fair bit of diversity in receptor sequences possible from a single genome. (stackexchange.com)
Many studies have recovered substantial differences in genome diversity. (phys.org)
Her primary research interests include host-pathogen interactions and molecular characterization of diversity and evolution of small RNA viruses. (cdc.gov)
Evolution affects biology at all levels, from molecules to ecosystems, and our courses and research projects provide unique opportunities to study this diversity. (lu.se)

Our findings provide insights into the alteration of potato genomes during the evolution of tuberization, and will enable genome design for new diploid hybrids. (nature.com)
These insights deepen our understanding of recent evolution in a model system, and highlight the potential of future museomic studies. (biorxiv.org)

polishCLR: a Nextflow workflow for polishing PacBio CLR genome assemblies. (usda.gov)

Genome duplication above the diploid state (a.k.a. polyploidy) is widespread among plants and animals and is particularly common in flowering plants and ferns. (uoguelph.ca)

It shows that in some cancers, the genome can be shattered into hundreds of fragments in a single cellular catastrophe, wreaking mutation on a massive scale. (biologynews.net)
The phenomenon is particularly common in bone cancers, where the distinctively ravaged genome is seen in up to one in four cases. (biologynews.net)

The pleiotropy evolution problem is widely known among secular geneticists, but rarely discussed in the popular media. (icr.org)
The researchers stated, 'Our study provided supportive evidence that pleiotropy constraints [sic] the evolution of TFs. (icr.org)

Whole-genome sequence analysis reveals differences in population management and selection of European low-input pig breeds. (genomeweb.com)
In addition, there are numerous significant differences between the chimp and human genomes. (creation.com)

I am currently a member of the Canadian Society of Ecology and Evolution, Society for the Study of Evolution, American Association for Higher Education and Botanical Society of America. (uoguelph.ca)
Ecology and Evolution, 12(11), e9474. (sb-roscoff.fr)

3 While scientists previously understood that the genome of this creature underwent a dramatic reorganization, they did not understand the full significance of the phenomena, because only the macronucleus has been completely sequenced. (icr.org)

Hybridization and Polyploidization are most common of the phenomenon observed in plants, especially in the genus Nicotiana leading to the duplication of genome. (scielo.br)

These synthetic biology platforms will lead to transformative advances in natural product discovery, drug development, and production. (aiche.org)

Now, the analysis of its genome shows interesting results for tumor research. (senckenberg.de)
Their study on the evolution and tumor resistance of baleen whales was recently published in the journal BMC Biology. (senckenberg.de)
The more cells you have, the greater is the chance that one of your cells will contract a mutation at a critical point in the genome, leading to tumor development. (senckenberg.de)

The first is that ATP production, coupled to electron transport, and translation of mitochondrial proteins represent the essence of mitochondrial function: these functions are common to all mitochondrial genomes and can be traced unambiguously and directly to an α-proteobacterial ancestor. (biomedcentral.com)

Anatomy11

Organisms35

Diseases4

Chemicals and Drugs26

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Phenomena and Processes130

Disciplines and Occupations12

Anthropology, Education, Sociology and Social Phenomena2

Technology, Industry, Agriculture3

Humanities2

Information Science16

Health Care7

Genes20

Evolutionary24

Genetics1

Genomics8

20171

Sequencing23

Molecular Biology7

Transposable elements2

Gene14

Chromosomes4

20181

Species18

20191

Pygmy right2

Computational Biology1

Mutations7

Different genomes1

Sequences in the genome1

Eukaryotic2

Bioinformatics1

Mitochondrial genome1

Genetic10

Human genome2

Variation1

Populations2

Drosophila1

Complete genome6

20161

Patterns1

Clade1

Reveal2

Illuminates1

Encodes1

Chimpanzee1

PLOS Biology1

Lineages4

Dynamics1

Analyses3

Diversity5

Insights2

Assemblies1

Diploid1

Cancers2

Pleiotropy2

Differences2

Ecology and Evolution2

Scientists1

Duplication1

Synthetic biology1

Tumor3

Proteins1