Genome 5. Medical search. Frequent questions

Comparative analyses of its 38.5-megabase genome, which encodes 13,210 predicted genes, reveal the species's unique wood-degrading machinery. (nature.com)
Nautilus shows a compact, minimalist genome with few encoding genes and slow evolutionary rates in both non-coding and coding regions among known cephalopods. (nature.com)
Researchers have generated a complete map of the areas of the genome that control which genes are "turned on" or "off. (sciencedaily.com)
Together with colleagues in Barcelona, researchers at the University of North Carolina at Chapel Hill have generated a complete map of the areas of the genome that control which genes are "turned on" or "off. (sciencedaily.com)
Many of the genes reconstructed in this process come from numerous individual fragments dispersed across the micronuclear genome-with some even being inverted in their orientation. (icr.org)
The genomes contained numerous genes that encode siderophore receptors, but no evidence of siderophore production was found, suggesting that they may obtain iron via interaction with other microorganisms. (nih.gov)
They discovered the octopus has an enormous genome-the complete set of genes-comparable in size to the human genome. (icr.org)
The project to fully decode the genome went on to test out its usefulness by searching for genes involved in seed size. (reading.ac.uk)
The ∼30 Mb genomes of the Plasmodium parasites that cause malaria each encode ∼5000 genes, but the functions of the majority remain unknown. (portlandpress.com)
This is critical because, while individual genes or genome fragments provide useful information on the metabolic potential of a community, in practice most biochemical transformations take place inside a cell, involving sets of genes structured in controlled pathways. (biomedcentral.com)
Current diagnostic PCR assays target a variety of SARS CoV-2 genes and the vast majority target sequences in regions of the SARS CoV-2 genome that are highly conserved. (who.int)
As the sequencing and gene annotation projects of entire genomes of many species are headed towards completion (see, e.g. [13] ), massive mapping efforts in biology are now focused on how the genes interact. (lu.se)
The Human Genome Project began in 1990 with the task of mapping the genes that would compose the human genetic code. (bvsalud.org)
Recently, the general coordinator of the Cancer Genome Project in Brazil, suggested the existence of a set of genes responsible for criminal behavior, discarding the relevant role of environmental variables (ontogenetic and cultural). (bvsalud.org)

4 . From the laboratory provider perspective, which of the following areas is additional guidance and practical recommendations for clinical whole-genome sequencing needed? (surveymonkey.com)
The article focused on the sequencing technology that will soon enable a full scan of a human genome for $1000, and to make the story come alive, I decided to go through the process myself. (discovermagazine.com)
The Baylor team has been intimately involved in many of the most important advances of genome sequencing over the last decade. (discovermagazine.com)
Once the Human Genome Project was completed, researchers were eager to start sequencing individual human beings, and to examine the genetic variations that define each individual's traits and quirks. (discovermagazine.com)
If the cost of sequencing a genome had continued at $3 billion a pop, there would be no way to conduct such experiments. (discovermagazine.com)
Another genetics pioneer, Craig Venter , was also sequencing his personal genome at the same time, but the Baylor team says Watson's was completed first. (discovermagazine.com)
In 2011, whole-genome sequencing revealed not only the genetic variants responsible, it also revealed which neurotransmitters were affected, and suggested a new drug regimen that worked remarkably well to control the twins' symptoms. (discovermagazine.com)
Dr. Stephen F. Kingsmore is president/CEO of Rady Children's Institute for Genomic Medicine (RCIGM), where he leads a multidisciplinary team that is pioneering the use of rapid genome sequencing to diagnose critically ill children, implement precision medicine, and screen for approximately 500 genetic disorders. (cdc.gov)
Among his achievements, Dr. Kingsmore holds two Guinness World Records for achieving the fastest molecular diagnosis using whole genome sequencing. (cdc.gov)
Rapid whole genome sequencing for diagnosis of single locus genetic diseases in critically ill children. (cdc.gov)
Automated prioritization of sick newborns for whole genome sequencing using clinical natural language processing and machine learning. (cdc.gov)
Reclassification of the etiology of infant mortality with whole-genome sequencing. (cdc.gov)
Dispatches from Biotech beginning BeginNGS: rapid newborn genome sequencing to end the diagnostic and therapeutic odyssey. (cdc.gov)
A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseases. (cdc.gov)
The role of genome sequencing in neonatal intensive care units. (cdc.gov)
Cost efficacy of rapid whole genome sequencing in the pediatric intensive care unit. (cdc.gov)
Rapid whole-genome sequencing in critically ill children: shifting from unease to evidence, education, and equitable implementation. (cdc.gov)
Rapid whole genome sequencing impacts care and resource utilization in infants with congenital heart disease. (cdc.gov)
A prospective study of parental perceptions of rapid whole-genome and -exome sequencing among seriously ill infants. (cdc.gov)
The increasing accessibility of whole-genome sequencing across research and clinical settings has improved our ability to predict antibacterial susceptibility, to track epidemics at the level of individual outbreaks and wider historical trends, to query the efficacy of the bacille Calmette-Guérin (BCG) vaccine, and to uncover targets for novel antitubercular therapeutics. (jci.org)
Whole-genome sequencing (WGS) of M. tuberculosis and related mycobacteria is now routine, allowing comparisons across time and space. (jci.org)
Whole genome sequencing (WGS) is increasingly used for pathogen identification and surveillance. (eurosurveillance.org)
With its ever-dropping price tag, whole-genome sequencing is taking off in Alzheimer's research. (alzforum.org)
Scientists from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have also started sequencing all of its participants' genomes. (alzforum.org)
These sequencing efforts are important because they represent some of the first to apply whole-genome sequencing approaches in AD. (alzforum.org)
The ultimate goal of any genetics experiment is to find the functional change in the DNA that matters biologically, and that requires whole-genome sequencing,' he told Alzforum. (alzforum.org)
These large-scale projects add to at least one other large whole-genome sequencing effort afoot. (alzforum.org)
The effort is part of the DOD SARS-CoV-2 Whole Genome Sequencing Action Plan, which brings together laboratories to conduct whole genome sequencing across the Military Health System in response to the COVID-19 pandemic. (health.mil)
The staff at Naval Health Research Center (NHRC) added whole genome sequencing capability to their surveillance program. (health.mil)
Phased diploid genome assembly with single-molecule real-time sequencing. (crossref.org)
Highly accurate long-read HiFi sequencing data for five complex genomes. (crossref.org)
Nanopore sequencing and the Shasta toolkit enable efficient de novo assembly of eleven human genomes. (crossref.org)
Initial sequencing and analysis of the human genome. (genome.jp)
International Human Genome Sequencing Consortium. (genome.jp)
However, single-cell sequencing requires a highly specialized laboratory facility, and single amplified genomes (SAGs) typically have fairly low genome coverage, due to the small amount of DNA in each cell and associated whole-genome amplification biases [ 9 ]. (biomedcentral.com)
The last decade's revolution in DNA sequencing throughput and cost has provided researchers with the unprecedented possibility of obtaining sequences from thousands of genomes at a time in natural samples. (biomedcentral.com)
In this paper we report on genome sequencing of 154 SARS-CoV-2 samples between June and July 2021 (Summer outbreak) in the Bailiwick of Jersey, a UK channel island. (medrxiv.org)
Since the publication of the first sequence at the beginning of 2020, viral genome sequencing has become a powerful tool to study the SARS-CoV-2 genome 1 , 4 . (medrxiv.org)
Are We Ready for Systematic Newborn Genome Sequencing? (medscape.com)
In the future, DNA samples could be taken from babies for whole genome sequencing to look for diseases that are likely to crop up later in life. (medscape.com)
There are several hundred rare diseases, and genome sequencing tools allow us to broaden our screening capabilities. (medscape.com)
Genome sequencing has already been studied for several years in multiple countries. (medscape.com)
New York's Guardian study requires all newborns taking part to undergo genome sequencing. (medscape.com)
One of its aims is to assess the medical, psychological, and financial impact of screening via genome sequencing at birth, compared with conventional screening. (medscape.com)
In the United Kingdom, Genomics England seeks to assess the feasibility, benefits, and risks of whole genome sequencing as part of the Newborn Genomes Programme , an analysis of 100,000 newborn genomes. (medscape.com)
Although France's initiative for genomic medicine, France Génomique 2025, does not envisage a neonatal genome sequencing screening program, a team in Dijon is studying several dozen genomes to determine the medical and financial benefits of such a program, explained Geneviève. (medscape.com)
Thanks to the advancement of sequencing technology, the plastid genome and the whole genome were sequenced in some durian cultivars. (who.int)
The Human Genome Project (HGP) started in the United States of America aiming at sequencing and mapping the human genetic code. (bvsalud.org)
In 2003, the sequencing of almost all human genome (HG) was announced. (bvsalud.org)
This study examined the added value of whole genome sequencing (WGS) for investigating a non-point source outbreak of Salmonella ser. (who.int)
2 Whole genome sequencing (WGS) is a high-resolution typing method that can help foodborne disease investigators distinguish outbreak cases from non-outbreak cases. (who.int)
The sequencing of the human genome revealed that at least 1% of the human genome consists of endogenous retroviral sequences, representing past encounters with retroviruses during the course of human evolution. (msdmanuals.com)
This manageable size together with the current advances in nucleotide sequencing technology means that partial and whole virus genome sequencing will become an essential component in epidemiologic investigations of disease outbreaks. (msdmanuals.com)

This list of sequenced plant genomes contains plant species known to have publicly available complete genome sequences that have been assembled, annotated and published. (wikipedia.org)
Unassembled genomes are not included, nor are organelle only sequences. (wikipedia.org)
For modeling and analysis - such as in cancer research, for example, which is what we do here - by far the most important parts of the human genome assembly are the parts that code for protein ( transcribed regions and their ORFs ), along with their adjacent regulatory sequences . (bcgsc.ca)
strain CF27, new sequences were generated, and an update assembly and functional annotation were undertaken, followed by a comparative analysis with other Acidithiobacillus species whose genomes are publically available. (frontiersin.org)
Comparing whole-genome sequences from those with and without AD or cognitive deficits will allow scientists to find more than just the genetic risk markers that genomewide association studies provide, said Tanzi. (alzforum.org)

2020 Nov 5;107(5):953-962. (cdc.gov)
Genome research 30, 9 ( 2020 ), 1291–1305. (crossref.org)

As a living information and communications system, the genome encodes patterns in single nucleotide polymorphisms (SNPs) reflecting human adaptation that optimizes population survival in differing environments. (scirp.org)
As a complex, dynamic information system, the human genome encodes and perpetuates the principles of life. (scirp.org)
The 5' terminus genome encodes nonstructural proteins (nsps) that are involved in the process of the virus infection cycle. (medrxiv.org)

The sequence of the human genome. (genome.jp)

Note 1 to entry: Gene editing is a subclass of genome editing ( 1.2 ). (nist.gov)
As it turns out, the germline genome of the micronucleus is fragmented into over 225,000 precursor DNA segments that are massively and precisely rearranged (unscrambled) during the construction of the new macronucleus and its nanochromosomes (most of which contain only one gene each). (icr.org)
Genome editing (also called gene editing) is a group of technologies that give scientists the ability to change an organism's DNA. (medlineplus.gov)
Here, we review the arrival of genetic screens in malaria parasites to analyse parasite gene function at a genome-scale and their impact on understanding parasite biology. (portlandpress.com)
The genomes' seasonal dynamics follow phylogenetic patterns, but with fine-grained lineage-specific variations, reflected in gene-content. (biomedcentral.com)
We describe the gene content, temporal dynamics and biogeography of a large set of new bacterioplankton genomes assembled from metagenomes. (biomedcentral.com)
Although gradual changes in trait complexity appear to have been facilitated by allelic turnover, key innovations are associated with gene and genome duplications. (lu.se)
These findings provide an important connection between the origins of biodiversity, coevolution, and the role of gene and genome duplications as a substrate for novel traits. (lu.se)
This review aims to update recent studies on the durian genome attributes and potential applications in the conservation of germplasm, authentication, and exploration of the gene structure and function of this specialty plant. (who.int)

2023 Feb 14;8(1):5. (cdc.gov)
The faba bean genome, which at 13 billion bases is more than four times the size of the human genome, has been sequenced for the first time and is published today (08 March 2023), in Nature . (reading.ac.uk)
Anim Genet;54(5): 649-651, 2023 10. (bvsalud.org)

In this study, we undertook extensive genome-wide comparative analyses of twelve species that conform the Pectobacterium genus. (mdpi.com)
These genomes represent novel species within typical freshwater and marine clades, including clades not previously sequenced. (biomedcentral.com)

UCSC Genome Browser on ViralProj281399 Apr. (ucsc.edu)

Cytogenet Genome Res (2003) 103 (1-2): 58-62. (karger.com)
Cytogenet Genome Res (2014) 142 (2): 107-111. (karger.com)

Genome research 27, 5 ( 2017 ), 722–736. (crossref.org)

Every infection involves at least two genomes, one belonging to the pathogen and the other to its host. (cdc.gov)

Here, we present a complete Nautilus pompilius genome as a fundamental genomic reference on cephalopod innovations, such as the pinhole eye and biomineralization. (nature.com)
The nautilus genome constitutes a valuable resource for reconstructing the evolutionary scenarios and genomic innovations that shape the extant cephalopods. (nature.com)
Therefore, genome studies of N. pompilius would not only shed light on the origin and evolution of cephalopod genomic novelties but also incentivize research on their biology and inform sustainable conservation. (nature.com)
The scientific entry was an information graphic showing a hive panel of genomic annotations in human, mouse and dog genomes. (bcgsc.ca)
2014. The Architecture of a Scrambled Genome Reveals Massive Levels of Genomic Rearrangement during Development. (icr.org)
However, insights into the population dynamics in the contact zones are hampered by a lack of ancient genomic data sampled at high spatiotemporal resolution 5-7 . (lu.se)
Negative-sense RNA viruses possess a single-stranded negative-sense genome that first must synthesize a complementary positive-sense antigenome, which is then used to make genomic negative-sense RNA. (msdmanuals.com)

If you were to pluck two cells from a chimeric mouse's body, you could get two different genomes - complete sets of chromosomes and genetic information. (livescience.com)
2 The ciliate Oxytricha trifallax has two different genomes contained in separate nuclei. (icr.org)

Targeted genome editing using CRISPR-Cas9 has been widely adopted as a genetic engineering tool in various biological systems. (mdpi.com)
The genome constructed by the Human Genome Project was a "consensus genome" made by combining the genetic material of a handful of people. (discovermagazine.com)
The overall aim is to understand post-9/11 long-term psychiatric outcomes and emotional health through an examination of their associated RDoC dimensions and underlying interactions among genome-wide genetic variation and direct/indirect WTC exposure(s). (cdc.gov)
To use and improve new biotechnologies involving human genome analysis and genetic mapping in the interests of risk-forecasting and the early diagnosis, prevention, prognosis and treatment of human diseases, particularly hereditary diseases and cancers, and with a view to a better understanding of the mechanisms of heredity. (europa.eu)
The completion of the human genome project has spurred a flurry of research into the exact genetic changes underlying disease. (sciencedaily.com)
These technologies allow genetic material to be added, removed, or altered at particular locations in the genome. (medlineplus.gov)
An extensive literature documenting physiological and ecological diversity make Daphnia an ideal model to study the genetic architecture of phenotypic variation in natural populations and the evolution of genome structure/function relationships in aquatic environments. (biomedcentral.com)
The goal is to compare these genomes to those from a group of healthy elderly controls to investigate genetic risk for AD and find the underlying molecular pathways of neuronal degeneration. (alzforum.org)
We therefore introduce the reader to CRISPR-based screens in the related apicomplexan Toxoplasma gondii and discuss how these approaches could be adapted to develop CRISPR/Cas9 based genome-scale genetic screens in malaria parasites. (portlandpress.com)
What do we do with the genetic data obtained at birth that won't become apparent until adulthood, if we find a BRCA1 or BRCA2 variant in a newborn's genome? (medscape.com)
Advancements in Genetic Diversity and Genome Characteristics of Durians (Durio spp. (who.int)
Huy T. G., Hoan N. K., Thi N. P. A., Khang D. T.. Advancements in Genetic Diversity and Genome Characteristics of Durians (Durio spp. (who.int)

Here we have developed a map that can guide scientists to regions of the genome that do appear to be functionally relevant, instead of a dead end. (sciencedaily.com)
Mutations in other regions of the genome may also be informative for known VOI/VOC detection. (who.int)

In March 2022, a flurry of publications announced the first ever complete assembly of a human genome. (bcgsc.ca)
Epub 2022 Nov 5. (nih.gov)

This genome constitution supports that the original hybrid from which the spore was obtained likely originated by a rare-mating event between a mating-competent S. cerevisiae diploid cell and either a diploid or a haploid S. uvarum cell of the opposite mating type. (frontiersin.org)
The present study reports the identification and structural and expression analysis of the AQPs found in the diploid progenitor genomes of A. hypogea i.e. (biomedcentral.com)
The giant diploid faba genome unlocks variation in a global protein crop. (reading.ac.uk)

In April of 2003, the federally funded Human Genome Project finished the first complete human genome. (discovermagazine.com)
Four genomes - The illustration, originally part of a poster , shows syntenic relationships between human, chimpanzee, mouse and zebrafish genomes. (bcgsc.ca)
Most of the human genome is uncharted territory -- entire stretches of sequence with no clear function or purpose," said Jason Lieb, Ph.D., associate professor of biology at UNC, a member of the UNC Lineberger Comprehensive Cancer Center and one of the senior authors of the study. (sciencedaily.com)
The information graphic showing the history of the human genome assembly is part of my series of designs created for the Scientific American Graphic Science page. (bcgsc.ca)
Because the human genome - a human genome - is complete. (bcgsc.ca)
You've probably already heard - and have been hearing for the last 15 years - that the human genome has been sequenced. (bcgsc.ca)
92% of the human genome is euchromatic. (bcgsc.ca)
The information is incorporated within a mostly fixed template, as well as within the structure of human genome sequence variation. (scirp.org)
Once the statistical distribution of variation reaches homeostasis in a given environment, a human population can be described in terms of the maintained order and patterns of polymorphisms in the whole genome. (scirp.org)
As dynamic sites in the human genome, SNPs are often highly correlated into combinations referred to as haploblocks whose haplotypes are maintained throughout generations with fixed frequencies within a given population. (scirp.org)
Genome editing is of great interest in the prevention and treatment of human diseases. (medlineplus.gov)
Ethical concerns arise when genome editing, using technologies such as CRISPR-Cas9, is used to alter human genomes. (medlineplus.gov)
Germline cell and embryo genome editing bring up a number of ethical challenges, including whether it would be permissible to use this technology to enhance normal human traits (such as height or intelligence). (medlineplus.gov)
Human Germline Genome Editing. (medlineplus.gov)
Thus, the resulting genome is a composite of two or three individuals, much like the original human genome, which was generated from the DNA of several individuals. (creation.com)
The purpose of this funding opportunity is to provide support for investigative groups to conduct genome-wide association (GWA) genotyping and/or replication studies using data and samples from human subjects on whom information is available for conditions/traits of public health importance and relevant environmental exposures. (nih.gov)
The DNA sequence and comparative analysis of human chromosome 5. (genome.jp)
Introduction: The Human Genome Project (HGP) has allowed for advances in diagnosis and prevention of diseases. (bvsalud.org)

For the first time, biologists recently sequenced the octopus genome 3 , meaning they determined the precise order of nucleotides that comprise the DNA molecule. (icr.org)
SARS-CoV-2 has a genome of 29,903 nucleotides, with 5'-cap structure and 3' poly(A) tail 9 , 10 . (medrxiv.org)

Nature biotechnology 37, 5 ( 2019 ), 540–546. (crossref.org)
SARS-CoV-2 has spread with the evolution of its viral genome since its emergence in late 2019. (medrxiv.org)

Its genome contains one genome copy from the S. uvarum parental genome and two heterozygous copies of the S. cerevisiae parental genome, with the exception of a monosomic S. cerevisiae chromosome III, where the sex-determining MAT locus is located. (frontiersin.org)

Signs of streamlining are evident in most genomes, and estimated genome sizes correlate with abundance variation across filter size fractions. (biomedcentral.com)
SARS-CoV-2 genome variation study enables a comprehensive understanding of virus transmission, rate of mutations, track evolution, development of vaccines, and treatment 5 . (medrxiv.org)

While the genome sequence was already transformative at the time, the past 25 years of progress have substantially increased its impact on TB taxonomy, drug discovery, resistance mechanisms, epidemiology, vaccine development, and pathogenesis. (jci.org)
Classification of viruses is principally according to their genome sequence taking into consideration nature and structure of their genome and their method of replication, but not according to the diseases they cause (see International Committee on Taxonomy of Viruses (ICTV), 2021 release ). (msdmanuals.com)

The importance of S. commune as a model system is also exemplified by the fact that its recombinant DNA constructs will express in other mushroom-forming fungi 5 . (nature.com)
Genome studies have helped uncover an entirely new branch of fungi that includes 600 seemingly unconnected fungi. (bgr.com)

doi:10.1038/s41467-017-02546-5. (wikipedia.org)

All appear male, though testing on their cells reveals that they also contain individual female genomes. (livescience.com)
Now a newly sequenced ciliate genome reveals unimaginable levels of programmed rearrangement combined with an ingenious system of encryption. (icr.org)
To conclude-the octopus genome reveals unexpected complexity and innate brain function for an invertebrate. (icr.org)
Comparing the genomes with globally distributed metagenomes reveals significant fragment recruitment at high sequence identity from brackish waters in North America, but little from lakes or oceans. (biomedcentral.com)

We assert that the stability of whole genome adaptation is reflected in the frequencies of maintained diversity in these common variants (SNPs) for a population in its environment. (scirp.org)

Although the genome is a foundation for understanding the metabolism, ecology and evolution of an organism, few bacterioplankton genomes have been sequenced, partly due to difficulties in cultivating them. (biomedcentral.com)

At the time, front page exposure of this sort has made Circos a very popular tool for visualization in genomics, and in particular, in cancer research where there is a need to illustrate differences between genomes. (bcgsc.ca)

The genomes encode low-specificity major facilitator superfamily transporters and high-affinity ABC transporters for sugars, suggesting that they are best suited to low-nutrient conditions. (nih.gov)

Thus, investigating the nautilus genome could furnish valuable insights into the evolutionary drivers of cephalopod innovations. (nature.com)
In several recent articles on the Neandertal mitochondrial genome, 3 , 4 , 5 I was hesitant to make many predictions about the full Neandertal nuclear genome because I had questions about the quality of ancient DNA (aDNA) and because I was not sure if I could trust the data, since it would have been thoroughly filtered by the evolutionary gatekeepers. (creation.com)

Epub 2009 Feb 5. (nih.gov)

This thematic series of companion papers constitutes the initial exploration of the genome biology of the waterflea (Daphnia) building on the first complete crustacean genome sequence. (biomedcentral.com)

A variety of mutations can cause this disorder, and Lupski wondered if a whole-genome scan could identify the particular mutation that caused his family's problems. (discovermagazine.com)
His genome scan, completed in 2010, did indeed reveal the mutation that is the source of Lupski's disorder. (discovermagazine.com)
The patterns of mutation in cancer genomes reflect the DNA damage and repair processes to which cancer cells and their precursors have been exposed. (lu.se)

Several approaches to genome editing have been developed. (medlineplus.gov)
Overall, these assays and approaches detect specific mutations or features such as insertions, deletions and point mutations in the SARS CoV-2 genome that are characteristic of a particular VOC/VOI using PCR. (who.int)

At the 25-year anniversary of this accomplishment, we describe how insights gleaned from the M. tuberculosis genome have led to vital tools for TB research, epidemiology, and clinical practice. (jci.org)
Greenfieldboyce, N. Octopus Genome Offers Insights Into One Of Ocean's Cleverest Oddballs . (icr.org)

This RFA will be administered by NHGRI ( http://www.genome.gov ) on behalf of the NIH ( http://www.nih.gov ). (nih.gov)

What are genome editing and CRISPR-Cas9? (medlineplus.gov)
The CRISPR-Cas9 system has generated a lot of excitement in the scientific community because it is faster, cheaper, more accurate, and more efficient than other genome editing methods. (medlineplus.gov)
CRISPR-Cas9 was adapted from a naturally occurring genome editing system that bacteria use as an immune defense. (medlineplus.gov)
Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. (medlineplus.gov)

Most of the changes introduced with genome editing are limited to somatic cells, which are cells other than egg and sperm cells (germline cells). (medlineplus.gov)
Based on concerns about ethics and safety, germline cell and embryo genome editing are currently illegal in the United States and many other countries. (medlineplus.gov)

Cornell will work with national research institutions in Uganda and Nigeria, the International Institute of Tropical Agriculture, Boyce Thompson Institute for Plant Research, and the U.S. Department of Energy Joint Genome Institute at the Lawrence Berkeley National Laboratory in California. (isaaa.org)

To understand these processes through comprehensive analyses of microbial ecology, evolution and metabolism, sequenced reference genomes of representative native prokaryotes are crucial. (biomedcentral.com)

In this study, we sequenced the complete genome of Nautilus pompilius in the hope of providing a critical reference for the evolution of cephalopods. (nature.com)
the complete genome sequence of Mycobacterium tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB), the leading cause of global infectious disease mortality. (jci.org)
The complete genomes of three strains from the phylum Acidobacteria were compared. (nih.gov)

They look like ordinary baby rhesus macaques, but Hex, Roku and Chimero are the world's first chimeric monkeys, each with cells from the genomes of as many as six rhesus monkeys. (livescience.com)
Analysis of the taxonomic composition of genomes of the Acidithiobacillia infers that they are chimeric in nature, supporting the premise that they belong to a particular taxonomic class, distinct to other proteobacterial subgroups. (frontiersin.org)

Project Baby Bear: Rapid precision care incorporating rWGS in 5 California children's hospitals demonstrates improved clinical outcomes and reduced costs of care. (cdc.gov)
Researchers have sequenced more than 100 ADNI genomes thus far, and the rest may be completed within the next six months, said Arthur Toga, University of California School of Medicine in Los Angeles. (alzforum.org)

Together with Senior Graphics Editor Jen Christiansen, we've looked at everything from the evolution of the genomes of SARS-Cov-2 strains to how pets contribute to the bacterial flora in your home . (bcgsc.ca)
Of the 120 strains of Variola virus in the Russian collection, 55 isolates had been selected for further investigation, involving viability studies, biological characterization and genome analysis. (who.int)

The parts that ultimately translated into protein exons account for just 2.58% of the genome. (bcgsc.ca)

The authors of the report state that a 'notable feature arising from this radical genome architecture is that a single MDS [macronucleus destined sequence] in the MIC may contribute to multiple, distinct MAC [macronucleus] chromosomes. (icr.org)
2014. The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome with 16,000 Tiny Chromosomes. (icr.org)

This paper demonstrates the power of biophysical modeling of population diversity for better understanding genome-environment interactions in biological phenomenon. (scirp.org)

Even though it took them longer than expected and there was general concern that they would not be able to pull off the task, 2 they managed to retrieve DNA and then used it to reconstruct the Neandertal genome. (creation.com)
We use automatic binning to reconstruct a large number of bacterioplankton genomes from a metagenomic time-series from the Baltic Sea, one of world's largest brackish water bodies. (biomedcentral.com)

The genome atlases allowed for distinguishing distinct DNA structures and highlighted suspicious high transcription zones. (mdpi.com)
Since there were two different and distinct mitochondrial genomes present, and since the bones came from different layers, at least two individuals, and probably three, were represented. (creation.com)

It's highly likely that within 10 to 15 years, all newborns will have their genome determined at birth for screening purposes. (medscape.com)

Genome-wide analysis revealed the presence of 32 and 36 AQPs in A. duranensis and A. ipaensis , respectively. (biomedcentral.com)
Analysis of RNA-seq data from A. hypogea revealed a similar expression pattern for the different AQP paralogs of AA and BB genomes. (biomedcentral.com)
The SIPs were the first to be unraveled via genome sequence analysis and are generally localized in the endoplasmic reticulum (ER). (biomedcentral.com)
These handouts, videocasts and supplementary materials are from the 2008 Current Topics in Genome Analysis lecture series. (genome.gov)
Sequence analysis of the Daphnia pulex genome holds some surprises that could not have been anticipated from what was learned so far from other arthropod genomes. (biomedcentral.com)

This life-threatening outcome of STEC infection is uncommon, developing in 5-10% of cases. (cdc.gov)
We suggest that close follow-up together with periodic endoscopic examination for all patients with persistent H. pylori infection and serum soluble E-cadherin level above 5 µg/mL is essential. (who.int)
Nous suggérons qu'un suivi attentif et un examen endoscopique régulier sont essentiels pour tous les patients atteints d'une infection à H. pylori persistante et présentant une concentration sérique de la E-cadhérine soluble supérieure à 5 µg/ml. (who.int)

The aim of the EU-funded RareBoost project is to recruit an internationally recognised expert as a leader for the new Unit for Rare Diseases at the Izmir Biomedicine and Genome Center (IBG), to direct its development into a leading basic and translational research centre for RDs. (europa.eu)
The aim of this RareBoost project is to attract an internationally recognized rare disease expert (ERA Chair holder) to the Izmir Biomedicine and Genome Center (IBG), where s/he will lead and direct the new Unit for Rare Diseases and guide its development towards an internationally recognized research facility for rare diseases. (europa.eu)
Currently, genome editing is used in cells and animal models in research labs to understand diseases. (medlineplus.gov)
The New York Genome Center and The Feinstein Institute for Medical Research announced in February that they, too, would partner with Illumina to sequence up to 1,000 AD patient genomes over four years. (alzforum.org)

Anatomy15

Organisms33

Diseases3

Chemicals and Drugs38

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Phenomena and Processes142

Disciplines and Occupations5

Technology, Industry, Agriculture3

Information Science15

Health Care5

Genes14

Sequencing53

Sequences5

20202

ENCODES3

Sequence of the human genome1

Gene9

20233

Species2

UCSC Genome Browser1

Cytogenet Genome Res2

20171

Pathogen1

Genomic7

Different genomes2

Genetic12

Regions of the genome2

20222

Diploid3

Human18

Nucleotides2

20192

Chromosome1

Variation2

Taxonomy2

Fungi2

10.10381

Reveals4

Variants1

Organism1

Genomics1

Encode1

Evolutionary2

Epub1

Biology1

Mutation3

Approaches2

Insights2

NHGRI1

CRISPR4

Germline2

Joint Genome In1

Analyses1

Complete3

Chimeric2

California2

Strains2

Protein1

Chromosomes2

Biological1

Reconstruct2

Distinct2

Newborns1

Analysis5

Infection3

Research4