MiceCropsScientistsOrganismsDiseasesResearchersRefinementGenesMammalSuccessful transplantPigsBehavioralLaboratory animalsPatient'sExperimentationCruelty is a majorRatsResearchTransgenic animalsOrgansUnnecessaryInvolvesImplicationsReductionModerateHumans and animalsHumanBiotechnologySeedsGeneticsContributesColleaguesCloningTraitsStrainCellsModelsDecadesAlzheimer'sVaccinationProteinStudiesCuriosity-drivenMonkeysWelfare of animalsEntailsFailuresFindingsPredictScientificFoodGenomeMoleculesStudySheepFoodsPeopleConcernsCompanyMouseDistressTime
Mice15
- Typical tests involve daily administration of a substance by gavage directly into the stomach of mice, rats, or other animals. (aerzte-gegen-tierversuche.de)
- Mice are genetically altered to replicate conditions like cancer, Alzheimer's, diabetes, and other human diseases. (aerzte-gegen-tierversuche.de)
- However in order to experiment they are using hundreds of genetically modified mice. (animalaid.org.uk)
- Looking at the statistics, there is one very clear reason why: breeding genetically modified mice. (understandinganimalresearch.org.uk)
- As I discussed in my last blog post, genetically modified mice can now replace the need for monkeys when testing the polio vaccine. (understandinganimalresearch.org.uk)
- Modified Handling for Mice: Handling mice by gripping the base of the tail has been shown to negatively impact animal welfare by increasing anxiety and aversion to handling. (awionline.org)
- Using genetically modified mice and cells grown in the laboratory, Wu et al. (elifesciences.org)
- Cholinergic basal forebrain lesion decreases neurotrophin signaling without affecting tau hyperphosphorylation in genetically susceptible mice. (atsbio.com)
- The majority of these animals, around 87 percent, were mice and rats. (mpg.de)
- The increase in the number of laboratory animals used since the year 2000 may be explained for the most part by the breeding of genetically modified animals, mainly mice. (mpg.de)
- However, mice and other mammals used in this kind of experiment do not usually contract SARS-CoV-2. (fapesp.br)
- In addition, there are countless examples of animal research resulting in new medical treatment methods, such as the discovery of the Rhesus factor in the blood of Rhesus monkeys, the development of operation techniques for organ transplants on dogs and pigs or the discovery of tumour-suppressing genes in the genetic make-up of mice. (mpg.de)
- Experiments have been done in mice who have been genetically engineered to be at risk of Alzheimer's disease. (mcmasteroptimalaging.org)
- The answers came from experiments where human brain cells were transplanted into the brains of genetically modified mice. (com.sa)
- [ 3 ] To prove that the level of Tbx5 is causal of ventricular septum formation rather than merely correlative, Bruneau's laboratory genetically engineered mice to express Tbx5 at a moderate level throughout the developing heart, as in turtles, instead of the normal steep left-right gradient. (medscape.com)
Crops7
- According to an Acres USA interview of plant pathologist Don Huber, Professor Emeritus at Purdue University, two modified traits account for practically all of the genetically modified crops grown in the world today. (theecologist.org)
- In fact, many countries have had to increase their legally allowable levels - by up to 50 times - in order to accommodate the introduction of GM crops. (theecologist.org)
- The poll also reveals broad support for genetically modified foods, with 69 per cent of people in favour of such crops saying they could help feed the world. (newscientist.com)
- The UK will reportedly continue its strict policies on GM crops after leaving the European Union , but there has been little public discussion. (newscientist.com)
- As though the havoc created by GM crops was not adequate, several experimental efforts relating to genetically modified or engineered animals are bringing a wide range of new risks and uncertainties. (countercurrents.org)
- These and related concerns should be raised more and more to prevent the genetic modification of animals from becoming as big an environmental and health risk as the technology of GM crops has become. (countercurrents.org)
- His books include India's Quest for Sustainable Farming and Healthy Food, 14 Questions About GM Crops and A Day in 2071. (countercurrents.org)
Scientists18
- Some believe that the Manda is a genetically engineered mammal created by Chinese scientists. (weeklyworldnews.com)
- The experiments carried out on animals are irrelevant (some scientists and doctors are now telling us this) and there are cruelty-free alternatives available. (animalaid.org.uk)
- Scientists have used this model in many ways, including watching how the connections among neurons grow and what happen to brain networks and behavior when a single gene is modified. (dana.org)
- To better understand both the physiology of the central nervous system and the different processes that allow it produce thoughts, feelings, and movements, many scientists rely on animal models. (dana.org)
- Scientists rely on C. elegans worms, fruit flies, rodents, non-human primates, and other types of animals to understand different aspects of brain function and behavior. (dana.org)
- Animal models showed scientists that neural signaling is electrical in nature. (dana.org)
- And the GE salmon's problems could stretch far beyond the dinner table: Scientists fear the modified fish may wreak havoc on the environment. (good.is)
- When these sheep were born in October 2012, scientists at the Animal Reproductive Institute of Uruguay immediately injected them with a green protein found in the Aequorea Victoria jellyfish. (mentalfloss.com)
- In the case of these sheep, scientists hope that one day they'll be able to use this sort of procedure to create animals with super health-boosting milk. (mentalfloss.com)
- Scientists in Japan wanted to see if the jellyfish gene was inherited by the second generation of a genetically modified monkey. (mentalfloss.com)
- As a first step in creating such replacement skin, scientists in Cincinnati have engineered bacteria-resistant skin cells in the lab and are now testing them in animals. (technologyreview.com)
- With the expansion of genetic modification, scientists are able to modify animal organs to decrease the chance of rejection within the human host. (grunge.com)
- While it may seem obvious to people nowadays, it took a surprisingly long time for some scientists to realize that animal body parts can't just be easily cut-and-pasted into a human. (grunge.com)
- In a note on 'Risks Associated with GM Farm Animals' the Federation of American Farm Scientists has stated-The genetic engineering of farm animals entails certain risks. (countercurrents.org)
- Animal research therefore presents scientists with an ethical dilemma as they have to weigh up the suffering of animals and humans. (mpg.de)
- Scientists in Germany can only carry out experiments on animals if they are indispensable for resolving unanswered questions. (mpg.de)
- Scientists suspect that cannibalism among locusts contributes to their swarming behavior, and swarms therefore constantly move on because individual animals are always on the run from conspecifics pursuing them. (sciencedaily.com)
- For further confirmation of PAN's function, the scientists used genetically modified locusts that could no longer produce PAN. (sciencedaily.com)
Organisms2
- We recently reviewed a research package on Genetically Modified Organisms (GMO). (optimumchoices.com)
- Animals have to be studied in order to understand how organisms work. (mpg.de)
Diseases11
- Prior to the June 2011 launch of our Victims of Charity campaign, we invited people who are suffering from diseases such as cancer and heart disease to get in touch with us, and declare their opposition to the animal experiments that are conducted in their name. (animalaid.org.uk)
- The ability to genetically alter animals allows researchers to study diseases and conditions in a way that is much more relevant to patients. (understandinganimalresearch.org.uk)
- He strived to create modified sheep that would produce milk with proteins that could treat human diseases. (yahoo.com)
- As we strive to better understand how the brain works, as well as how different brain-related diseases may arise, it is important to conduct experiments. (dana.org)
- Most of the drugs currently on the market used to treat different neuropsychiatric diseases were born from studies first done in animal models. (dana.org)
- These changes led to symptoms in animal models of the diseases. (elifesciences.org)
- Prion diseases, or transmissible spongiform encephalopathies, comprise a group of fatal neurodegenerative disorders in humans and animals for which there are no effective treatments or cures. (elifesciences.org)
- The use of these animals enables both the initial investigation and more detailed study of many diseases. (mpg.de)
- These include health hazards relating to transfer of diseases from genetically engineered animals to normal animals as well as to human beings. (countercurrents.org)
- Research on animals can therefore provide valuable information about the origin of diseases and the effect of medications. (mpg.de)
- In animals, we can more easily perform experiments and there is some animal evidence that sleep could prevent diseases. (mcmasteroptimalaging.org)
Researchers10
- Researchers in China are exploring the use of gene-editing technologies to create customized animals. (scienceblogs.com)
- We declare our solidarity with all researchers who have to rely on animal experiments. (wikipedia.org)
- The extra precision and relevance of studying genetically modified animals allows researchers to use fewer and less sentient animals. (understandinganimalresearch.org.uk)
- The members of ELLA are researchers, veterinarians, experts in animal care and experts in practical animal protection work or ethical questions. (oulu.fi)
- To study brain activity over longer periods of time and in greater depth requires methods that are far too risky for human test subjects, and so some researchers use animal models. (dana.org)
- While other researchers had bred partially fluorescent pigs, these genetically modified pigs had not only glowing skin and eyes, but also organs, including the heart. (mentalfloss.com)
- The researchers are now planning experiments in animal models. (technologyreview.com)
- Cell cultures also help researchers to avoid conducting research involving animals. (mpg.de)
- Researchers still need to assess the long-term viability of pig organs in humans and the possibility of a deadly virus transferring from animal to person. (wng.org)
- While some researchers apply epidemiological models to animal data, others only look into molecular and cellular biology. (cdc.gov)
Refinement3
- The Animal Welfare Act has stipulated the principles of the "3Rs" of replacement, reduction, and refinement. (jnss.org)
- Replacement refers to proactively adopting methods which avoid or replace the use of animals, reduction relates to effective methods that reduce the number of animals being used, and refinement refers to efforts to improve animal care and experimental procedures to minimize study-related pain and distress out of respect for the life of experimental animals. (jnss.org)
- Animal test alternatives: Refinement, reduction, replacement. (cdc.gov)
Genes8
- A very similar set of genes is induced in unlesioned animals by administration of the psychostimulant cocaine or the antipsychotic eticlopride, although in distinct striatal cell populations. (jneurosci.org)
- The yeast ML01 was modified using a shuttle vector containing a chromosome integration cassette with genes for malolactic enzyme, malate transporter (permease), regulatory genes and a sequence directing homologous recombination at a chromosomal locus (not specified in the FDA report), and the antibiotic phleomycin gene was used as a selectable marker via another plasmid. (i-sis.org.uk)
- This level of precision can be applied to single-celled embryos in the very early stage of development and avoids many of multiple steps for creating genetically modified animals: several genes can be edited at once, both copies of the gene can be changed and there is no need for a supply of embryonic stem cells. (understandinganimalresearch.org.uk)
- But over the past century, experimental work using animal models has given us many insights into the molecules, genes, cells, and fibrous networks that make up the central nervous system. (dana.org)
- If fish get out, because it's a GE animal, those new combinations of genes will persist in the wild in a way that is not analogous to the farmed Atlantic salmon that are currently getting out and breeding with wild Atlantic salmon," Leonard says. (good.is)
- Alba was actually just one component of the project, which was also supposed to include a public debate about the practice of manipulating genes in animals for research. (mentalfloss.com)
- All of the modified marmosets carried the genes in their body. (mentalfloss.com)
- This was the first time a genetically modified animal passed such genes down a generation. (mentalfloss.com)
Mammal1
- Polly, born in 1997, was the first genetically modified cloned mammal. (yahoo.com)
Successful transplant2
- But scientific papers declaring new breakthroughs, which claimed to make the successful transplant of GM animal organs into humans possible, have been shown to be dangerously misleading. (gmwatch.org)
- In September, a surgical team at NYU Langone Health performed the first successful transplant of a genetically modified animal kidney to a human. (wng.org)
Pigs1
- You may have noticed that private companies are already selling genetically-modified micro pigs for pets. (scienceblogs.com)
Behavioral3
- 2022. The promise of behavioral tracking systems for advancing primate animal welfare. (awionline.org)
- Behavioral experiments with the migratory locust Locusta migratoria showed that cannibalism rates increased with the number of gregarious animals that were kept together in a cage. (sciencedaily.com)
- Behavioral experiments with genetically modified locusts whose OR70a receptor was no longer functioning again showed a strongly increased cannibalism rate, which is due to the fact that the cannibalism stop signal can no longer be perceived by the locusts without the corresponding receptor. (sciencedaily.com)
Laboratory animals6
- 1] (The revised EU Directive provides for the use of fewer laboratory animals for scientific purposes in the future and better reconciles the needs of research with the protection of animals without making research more difficult. (wikipedia.org)
- In Japan, animal studies are regulated by The Act on Welfare and Management of Animals (hereafter referred to as the " Animal Welfare Act ") and The Standards Relating to the Care and Management of Laboratory Animals and Relief of Pain (hereinafter referred to as the " Standards ") [1, 2, 12, 13]. (jnss.org)
- Under the principles of 3Rs, the Standards have stated that, since animal experiments are "indispensable for advancing life sciences and developing medical technologies," laboratory animals "shall be appropriately cared for, managed, and used for scientific purposes with due appreciation of and responsibility for their role. (jnss.org)
- You may be eating genetically modified food every day which scientific experiments have repeatedly demonstrated can cause sickness and even death in laboratory animals. (weboflove.org)
- Cats and dogs represent 0.2 percent of all laboratory animals, and monkeys - usually rhesus monkeys - account for 0.1 percent. (mpg.de)
- The number of laboratory animals used in Germany in the 1990s was successfully reduced from over 2.5 million in 1989 to below 1.5 million in 1999. (mpg.de)
Patient's1
- A patient's skin cells, genetically modified and grown in a test tube, could provide the next generation of artificial skin. (technologyreview.com)
Experimentation3
- So it's undoubtedly time for a review of exactly what benefits animal experimentation has brought us, and whether we can continue to accept such large-scale suffering and waste of life. (gmwatch.org)
- Besides, it has been extensively proven that results from animal experimentation are not transferable to humans. (animalaid.org.uk)
- Animal experimentation always requires a licence. (oulu.fi)
Cruelty is a major2
- While there's no shortage of reasons to oppose GM, animal cruelty is a major one. (gmwatch.org)
- I believe that animals should have rights the same as humans, and freedom from pain and cruelty is a major right. (animalaid.org.uk)
Rats1
- In addition there is a lack of information regarding the presence of mast cells in dental pulp of rats, which are animals used to study important aspects of the pathophysiology of dental pulp in vivo 6 . (bvsalud.org)
Research40
- Take for example research at the Shaanxi Provincial Engineering and Technology Research Center for Shaanbei Cashmere Goats where animals have been genetically-modified to have longer hair (i.e. more wool) and more muscles (i.e. meat). (scienceblogs.com)
- The Basel Declaration is a call for greater transparency and communication on the use of animals in research. (wikipedia.org)
- At the same time, they demand that essential animal experiments for obtaining research results remain permitted both now and in the future. (wikipedia.org)
- Animal experiments will remain necessary in biomedical research for the foreseeable future, but we are constantly working to refine the methods with animal welfare in mind. (wikipedia.org)
- 2] The signatories to the Declaration commit, amongst other things, to the use of animal experiments only when the research concerns fundamentally important knowledge and no alternative methods are available. (wikipedia.org)
- The authors of the Basel Declaration acknowledge the need for greater discussion of animal experiment issues in public and also of the risks of research approaches and possible misuse of new technological developments. (wikipedia.org)
- 4] With regard to the improvement of information for the public on research involving experiments the signatories to the Basel Declaration commit to the following: We communicate openly and with transparency - also with regard to animal experiments. (wikipedia.org)
- We proactively address the problems and openly declare that part of our research involves animal experiments. (wikipedia.org)
- The initial signatories to the Basel Declaration see the tendency to restrict animal experiments, especially in the field of basic research, as a major risk. (wikipedia.org)
- Though cloning is rarely used for this purpose today, the idea that we can tweak animals' DNA to make them healthier and more productive remains an important research topic. (ed.ac.uk)
- Basic research has accounted for more than half of all animal experiments in Germany for years. (aerzte-gegen-tierversuche.de)
- Some argue that animal suffering in the name of research is justified by benefits to humans, but there are clearly none in these appalling experiments. (gmwatch.org)
- Moreover, we have a choice of systems of healthcare and research, many of which have never involved animals. (gmwatch.org)
- Medical research charities claim that they conduct animal research for the benefit of patients, but animal 'models' of human disease not only cause immense suffering, they are also unreliable and the results gained can be dangerously misleading. (animalaid.org.uk)
- Non-animal research methods allow us to obtain data that is more accurate and relevant to human health, and therefore more likely to lead to effective treatments. (animalaid.org.uk)
- Get the latest articles and news from Understanding Animal Research in your email inbox every month. (understandinganimalresearch.org.uk)
- This database, created in 2000, is updated every three months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research. (awionline.org)
- The application for change can be used to apply for changes related to the research procedure in question, such as increasing the number of animals, adding a new animal species, continuing the experiment for longer or further procedures. (oulu.fi)
- These ethical considerations underscore the importance of animal studies in neuroscientific research as mentioned above. (jnss.org)
- Basic Guidelines on Animal Experiments etc. in Research Institutions, etc. (jnss.org)
- That's because the research facility was owned by AquaBounty Technologies , a biotech company that creates salmon eggs to hatch genetically engineered fish. (good.is)
- According to the Center for Food Safety , some studies have linked genetically modified foods to allergic reactions, while other research suggests that transgenic fish may be more susceptible to disease . (good.is)
- A research institute in France actually created the rabbit for Kac - the florescent jellyfish protein was injected into a fertilized rabbit egg - and later hesitated over releasing the animal due to protests from animal rights groups over Alba's very creation. (mentalfloss.com)
- The experiment was meant to prove the principle of transgenic animals, particularly dogs, who, due to their lifespan and reproductive cycle, are good stand-ins for human disease research. (mentalfloss.com)
- A research paper prepared by the Humane Society of the USA (HSUSA) and titled 'Welfare Issues with Genetic Engineering and Cloning of Farm Animals' has stated-"Developments in biotechnology have raised new concerns about animal welfare as farm animals (may) now have their genomes modified ( genetically engineered ) or copied ( cloned) to propagate certain traits useful to agribusiness such as meat yield or feed conversion. (countercurrents.org)
- Is the use of animals in research experiments ethical? (mpg.de)
- Animal research also aims to contribute towards preventing or at least alleviating human suffering. (mpg.de)
- They therefore believe conducting animal research for human good is justified. (mpg.de)
- Only 0.3 percent of all animals used for human needs are used in research (as of 2015). (mpg.de)
- Is conducting animal research for basic research justified? (mpg.de)
- It is only thanks to this research that we know today how animals cope in their environment and what they need to survive. (mpg.de)
- Animal research enables desired and undesired effects to be predicted. (mpg.de)
- How high is the success rate of animal research? (mpg.de)
- One thing is nevertheless clear - without animal research many people would die owing to a lack of medical treatment and of toxins. (mpg.de)
- Why don't you replace animal research with computer modelling? (mpg.de)
- However, cell cultures do not make all animal research superfluous. (mpg.de)
- Animal organs could shorten transplant waiting lists, but the research prompts ethics debates about the distinction between animals and humans. (wng.org)
- But he worried that xenotransplantation research has already creeped into dangerous territory with the development of human-animal chimeras . (wng.org)
- And, more significantly, the progress achieved recently in human genomics research,1 the creation of genetically-modified foods2 and the gene therapy3 have added to the major bioethical issues the Region is likely to face in the near future. (who.int)
- A logical approach to remedy the situation for low dose research was to conduct well controlled animal studies with hundreds of animals, nevertheless, even after many such studies were completed our understanding of biological basis for risk from low dose radiation exposure is still not conclusive. (cdc.gov)
Transgenic animals1
- Americans have never eaten transgenic animals before, so policies on how to safely approve them as dinners just don't exist. (good.is)
Organs1
- The family of the brain-dead woman, who was an organ donor, consented to the experiment after her organs were deemed unfit for donation. (wng.org)
Unnecessary2
- Also, this kind of animal experiments is unnecessary. (aerzte-gegen-tierversuche.de)
- I believe experimenting on animals is unnecessary and cruel, and believe that in this day and age there are many other, more reliable, alternatives. (animalaid.org.uk)
Involves1
- Xenotransplants involve putting the well-being of a human above the well-being of an animal, which involves not only the death of the animal but the lifestyle it must be raised in to minimize "the risk of acquired infections. (grunge.com)
Implications1
- If performed incorrectly due to technical difficulties, inexperience, or animal resistance, oral gavage may have animal welfare implications such as esophageal and gastric rupture. (awionline.org)
Reduction1
- They are therefore contributing to the reduction of experiments. (mpg.de)
Moderate1
- Data from long concluded experiments with moderate and high doses of radiation delivered by internal emitters were significantly re-interpreted because the length of the cell cycle was used as one of the variables in the analysis. (cdc.gov)
Humans and animals1
- Given that all humans and animals sleep, it is logical that sleep should be important to health. (mcmasteroptimalaging.org)
Human13
- Stem cells, human and animal enhancement and genetic modification are just some of the areas she explores. (ed.ac.uk)
- Over the last 5 years it has been discovered - through human patients - that this drug has many more undesirable side effects than were discovered by animal testing, and many people (including myself) have been taken off them. (animalaid.org.uk)
- I am a vegan and have been an animal and human rights campaigner for 30 years. (animalaid.org.uk)
- Why can't we just study the human brain instead of using animal models? (dana.org)
- Animal studies are a mainstay for scientific and medical advances related to the human brain, and their use will allow for assessment of the safety and benefits of new diagnostic and therapeutic modalities. (jnss.org)
- AquaBounty never released information about the outbreak to the public, despite the fact that its GE salmon is poised to become the first transgenic animal to be approved for human consumption. (good.is)
- Here, cells that were genetically modified to produce higher levels of a protein known as human beta defensin 4 are shown in green. (technologyreview.com)
- Humans have been attempting xenotransplants, also known as animal-to-human transplants, for hundreds of years with historically little success. (grunge.com)
- And although the idea of informed consent gets murky when the options are between an extremely experimental procedure and death (in most instances), a surprisingly large number of people participated in these types of experiments, leading us to the pig-to-human heart transplants of the 21st century. (grunge.com)
- There's also the risk of animal-to-human disease transmission, known as zoonosis, which may lead to those with a xenotransplant being subjected to restrictions or temporary detentions. (grunge.com)
- And considering that these were some of the options available, anyone who was getting transfusions of animal blood was comparatively getting the better end of the deal, short of actually having a human blood transfusion of the corresponding blood type. (grunge.com)
- A mouse strain has been genetically modified to express human ACE-2, the protein used by the virus to invade cells. (fapesp.br)
- Animal-to-human transplants, or xenotransplants, have the potential to shorten organ transplant waiting lists. (wng.org)
Biotechnology2
- In this widely quoted paper titled 'The Biotechnology Bubble' Dr. Mae-Wan Ho (of Bio-Electrodynamics Lab of the Open University in the UK), Joe Cummins (Professor Emeritus of Genetics in Canada) and Hartmut Meyer summarized the results of several experiments, trials and commercial releases of GMOs, with special emphasis on animals. (countercurrents.org)
- The animal biotechnology company Revivicor provided a genetically engineered pig for the experiment. (wng.org)
Seeds1
- And now global food control has nearly been achieved, by reducing seed diversity with GMO (genetically modified) seeds that are distributed by only a few transnational corporations. (theecologist.org)
Genetics1
- Wilmut's work at The Roslin Institute in Edinburgh continued to push the boundaries of animal genetics. (yahoo.com)
Contributes1
- From this perspective, every experiment carried out correctly in terms of quality contributes to increasing our knowledge about nature. (mpg.de)
Colleagues2
- So Supp and colleagues genetically modified skin cells to produce higher levels of an antibacterial protein. (technologyreview.com)
- In a remarkable set of experiments, the developmental biologist Benoit Bruneau and his colleagues uncovered the molecular basis for ventricular septum formation. (medscape.com)
Cloning1
- Polly was Wilmut's last cloning experiment. (yahoo.com)
Traits1
- Then of course there are grave doubts regarding the scientific basis of the technology and to what extent it can actually succeed in achieving its aim regarding transfer of certain genetic traits, quite from the hazards involved in this, as well as the ethics of playing around with an uncertain technology regardless of serious harm that may be caused to the health and welfare of animals in the process. (countercurrents.org)
Strain1
- In 2003, the United States Food and Drug Administration (FDA) designated the GM yeast strain Saccharomyces cerevisae ML01 'generally recognized as safe' (GRAS). (i-sis.org.uk)
Cells9
- We have demonstrated for the first time that T cells can be modified with DAbR1, enabling their in vivo tracking via PET and SPECT. (snmjournals.org)
- This results in a chimeric mouse that has only some cells that are genetically altered. (understandinganimalresearch.org.uk)
- While Dolly proved that cells could be used to create a copy of the animal they came from, Wilmut's next experiment proved that they could also be altered. (yahoo.com)
- The venom increased monocytes, neutrophils and NK cells, and this effect was the opposite of that observed in the animals treated with MTX. (nature.com)
- Experiments showed that adding a large amount of normal PrP to the cells could prevent these effects. (elifesciences.org)
- Skin cells genetically engineered to be resistant to bacteria could reduce infections and improve chances of survival among burn victims. (technologyreview.com)
- Genetically modified skin cells may help protect cultured skin substitutes from infection. (technologyreview.com)
- Experiments with cultured cells and animal models may also be conducted to understand how the virus acts on the olfactory epithelium. (fapesp.br)
- The cells firstly have to be taken from the animals. (mpg.de)
Models5
- This encompasses animal testing for drug development, where animals serve as "disease models. (aerzte-gegen-tierversuche.de)
- What are animal models? (dana.org)
- Animal models are built upon the idea that many species of animals have a behavior or disease similar to one seen in humans. (dana.org)
- What have we learned from animal models? (dana.org)
- It is a fact that insights gained from animal models can be applied to humans. (mpg.de)
Decades2
- The Chinese have been experimenting with genetically-modified animals for decades. (weeklyworldnews.com)
- For the past few decades, our techniques for creating genetically modified animals have been technically challenging. (understandinganimalresearch.org.uk)
Alzheimer's1
- Although these studies are conducted in animals it may suggest important relationships between sleep and Alzheimer's disease. (mcmasteroptimalaging.org)
Vaccination1
- It found strong support for legalised assisted dying, a complete ban on animal experiments, and compulsory childhood vaccination. (newscientist.com)
Protein1
- The experiments showed that one end of the protein, called the N-terminus, is involved in the movement of electrical charges across the cell membrane and is able to cause cell degeneration. (elifesciences.org)
Studies7
- This is due to the fact that, as proven by many scientific studies, the transferability of findings from animal experiments to humans is by no means assured. (aerzte-gegen-tierversuche.de)
- Animals are used in medicine, veterinary science, and biology studies to teach students basic biological knowledge although a broad spectrum of pedagogically superior, animal-free teaching methods exist. (aerzte-gegen-tierversuche.de)
- Some studies using animals are not animal experiments. (oulu.fi)
- These guidelines are intended to assist JNS members to understand the significance of, and legitimately implement, legally compliant animal studies. (jnss.org)
- Here, a look back at the radiant animals at the center of these genetic studies throughout the last decade. (mentalfloss.com)
- In 2009, almost 2.8 million animals were used for animal studies and other scientific purposes in Germany. (mpg.de)
- In this paper we argue that the problem lies in the fact that our approach to animal studies is not comprehensive but conceptually binary. (cdc.gov)
Curiosity-driven1
- As a scientist I have been passionately curiosity driven, always looking forward to the next experiment and exploring new ideas. (lu.se)
Welfare of animals1
- This paper has lamented the lack of regulations in this work to protect the welfare of animals. (countercurrents.org)
Entails1
- This procedure entails significant suffering for the animals, yet it does not yield therapies that accurately address the underlying processes in humans. (aerzte-gegen-tierversuche.de)
Failures2
- Of course gene editing does not always work so there may be many failures before creating a successfully transformed animal. (scienceblogs.com)
- The publication of leaked documents shows that a quarter of the dozens of baboons involved in the experiments died from "technical failures", often in extreme agony. (gmwatch.org)
Findings1
- Such findings continually also result in new methods, especially in medicine, as what makes animals ill is often also harmful to humans. (mpg.de)
Predict2
- Given the significant differences in organ function and metabolism between animals and humans, the results of such experiments do not accurately predict the toxicity for humans. (aerzte-gegen-tierversuche.de)
- They can sometimes help to predict the possible results of experiments which can then be verified using very specific experimental methods. (mpg.de)
Scientific5
- The signatories to the Basel Declaration are actively seeking to show that science and animal welfare are not diametrically opposed and to make a constructive contribution to the dialogue taking place in society - for example in the incorporation of the new EU Directive of 22 September 2010 on the protection of animals used for scientific purposes into the national laws. (wikipedia.org)
- The experiments do not serve the well-being of the animal, but aim to answer a wide variety of the researcher's scientific questions. (aerzte-gegen-tierversuche.de)
- Animals are used to address even the most devious scientific inquiries, driven more by a sense of tradition than by any meaningfulness. (aerzte-gegen-tierversuche.de)
- Using animals for scientific or educational purposes always requires a licence. (oulu.fi)
- It is important to understand that an animal model is not just the animal studied-it also includes the type of scientific methodology used. (dana.org)
Food4
- The aim is to make life healthier for farm animals and food production safer for humans. (ed.ac.uk)
- The SMC introduced these experts to the media solely by listing the universities and public institutions that employ them, failing to give the full flavour of their interests: seven out of eight are either evangelical advocates of GM food, or have received funding from, or worked with, prominent biotech corporations. (gmwatch.org)
- Rather than actually create said policies, the Food and Drug Administration-the agency with the power to send the fish to supermarket coolers-found a loophole: Treat a GE animal like a new animal drug. (good.is)
- In addition there are the additional risks from consuming the food based on or obtained from genetically engineered animals. (countercurrents.org)
Genome1
Molecules1
- Molecules from animal venoms are promising candidates for the development of new drugs. (nature.com)
Study3
- A second study described a baboon which survived for 39 days with a GM pig heart as healthy throughout. (gmwatch.org)
- Before one can begin an experiment, the study must be given a valid licence issued by the National Animal Experiment Board in Finland, ELLA. (oulu.fi)
- A recent animal study also showed that clearance of pathologic (i.e. 'bad') proteins doubles during sleep (7). (mcmasteroptimalaging.org)
Sheep1
- Dolly the sheep was part of a series of experiments aimed at developing a method of producing genetically modified animals. (ed.ac.uk)
Foods1
- Sixty to seventy percent of the foods in US supermarkets are now genetically modified. (theecologist.org)
People3
- What does experimenting with other animals tell us about people? (dana.org)
- But when did people start trying to patch up their bodies with the body parts of animals? (grunge.com)
- The importance of humans is greater than that of animals for most people. (mpg.de)
Concerns1
- This fish flu flub is just the latest bullet point on a laundry list of concerns surrounding the genetically modified fish. (good.is)
Company2
- The GM-organ experiments were undertaken by a company owned by gene giant Novartis. (gmwatch.org)
- The company distributing the GM yeast, Springer Oenologie, Lesaffre Group of North America, stated that the malate transporter gene and malolactic gene were both controlled by the phosphoglycerate kinase gene (PGK1) promoter and transcription terminator. (i-sis.org.uk)
Mouse1
- For example, many neuroscientists use an animal model called a transgenic mouse , or a mouse that has been genetically modified in specific ways. (dana.org)
Distress2
- Depending on the substance the animals may experience respiratory distress, nausea, diarrhea, or might die. (aerzte-gegen-tierversuche.de)
- Project licence is always needed when the pain or distress to the animal is equivalent or higher than the pain caused by an ordinary injection. (oulu.fi)
Time2
- Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic. (awionline.org)
- Memories of failed experiments, rejected papers, and frustrat- ing struggles for grant money all seem to kindly fade away with time. (lu.se)