• The present invention provides a method of inducing an immune response in a non-invasive mode, comprising the step of: contacting skin of an individual in need of such treatment topically by applying to said skin an immunologically effective concentration of a genetic vector encoding a gene of interest. (google.com)
  • Also provided is a method of inducing an anti-tumor immune response in an animal in need of such treatment, comprising the step of: contacting skin of said animal topically by applying to said skin an immunologically effective concentration of a vector encoding a gene which encodes an antigen which induces an anti-tumor effect in said animal following administration. (google.com)
  • Some of the different types of viruses used as gene therapy vectors: Retroviruses - A class of viruses that can create double-stranded DNA copies of their RNA genomes (reverse transcription). (scribd.com)
  • The vector is part of a clinical trial investigating the use of gene therapy to cure choroideremia , a disease that affects an estimated 100,000 people worldwide. (healthcanal.com)
  • Researcher Dr. K. Reed Clark, director of the Clinical Manufacturing Facility at the Center for Gene Therapy , Nationwide Children's Hospital, and his team produced the clinical-grade vector that is administered to patients in the trial. (healthcanal.com)
  • 1. A method of non-invasively inducing a systemic immune response, comprising topically administering, a plasmid DNA and liposome complex vector that encodes a gene of interest and expresses a protein encoded by the gene of interest, to the skin of a mammal, in an effective amount to induce said systemic immune response to said protein, wherein a systemic immune resonse to said protein is induced in said mammal. (google.com)
  • This thesis investigates GAs as a method for the Vector Quantization (VQ) problem of image compression. (auraria.edu)
  • Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition. (mcw.edu)
  • The new vector, pLAFR1, is 21.6 kb long, confers tetracycline resistance, contains a unique EcoRI site, and can be mobilized into and stably replicates within many Gram-negative hosts. (nih.gov)
  • Researchers are experimenting introducing a 47th (artificial human) alongside the standard 46 .Carrying substantial amounts of genetic code. (scribd.com)
  • The most common vector is a virus genetically altered to carry normal human DNA. (scribd.com)
  • Combined with wavelet packet decomposition and isometric mapping (Isomap), the sensitive feature vectors are obtained and stored in database. (hindawi.com)
  • Meanwhile, the sensitive feature vectors are randomly chosen from the database and constitute training samples and testing samples. (hindawi.com)
  • The clinical vector manufacturing facility at Nationwide Children's Hospital is outstanding, and Dr. Clark and his team deserve congratulations for providing a clinical vector that for the first time offers these patients the possibility of an effective therapy. (healthcanal.com)
  • Whether you're a global ad agency or a freelance graphic designer, we have the vector graphics to make your project come to life. (vectorstock.com)
  • We believe it holds great promise for the treatment of other genetic causes of blindness such as retinitis pigmentosa. (healthcanal.com)
  • I cannot describe the excitement in thinking that we have designed a genetic treatment that could potentially stop it in its tracks with one single injection. (healthcanal.com)
  • Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants. (nih.gov)
  • The aim of this study was to develop, refine and evaluate an alternative methodology, which enables better preservation of large numbers of individual schistosome larval stages and eggs collected in low resource endemic areas, to provide PCR-quality DNA for multi-locus genetic analysis. (biomedcentral.com)
  • The pluripotent state overrode the limiting genetic lesions, suggesting potential future therapy to replicate the enzymatic activity. (childrenshospital.org)