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  • docetaxel
  • Addition of epirubicin or docetaxel to the platinum-fluoropyrimidine combination is common in Europe and the USA because of the survival benefit demonstrated by randomized clinical trials [ 9 , 10 , 11 ], but it is still under debate whether the survival benefit justifies the additional toxicity of these three-drug combinations. (springer.com)
  • gene
  • For example, patients with lung cancer are now often assessed for mutations in the epidermal growth factor receptor ( EGFR ) gene because such genetic alterations confer susceptibility to inhibitors of the EGFR kinase ( 3, 4 ). (aacrjournals.org)
  • Our previous and others studies showed that a loss of heterozygosity on the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer, which implies the presence of a tumor suppressor gene (12, 13) . (aacrjournals.org)
  • doctor
  • Epirubicin is always given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation. (medbroadcast.com)