• 12 of these loci were new (not previously identified by other genetic studies). (preeclampsia.org)
  • Given that "31-35% of preeclampsia predisposition has been attributed to maternal genetics", genetic analyses to find specific loci associated with the disorder could help to predict at-risk patients. (preeclampsia.org)
  • The 18 independent loci identified by this genome wide analysis study presents new avenues of research for identifying women who may be at genetic risk of developing preeclampsia. (preeclampsia.org)
  • A high genetic diversity was observed in overall loci for all populations with heterozygosity (Ho) value of 0.77. (up.ac.za)
  • The highest heterozygosity (0.93) across all markers was observed in the Mecha chicken population, while the lowest heterozygosity across all loci (0.66) was observed in the White Leghorn breed. (up.ac.za)
  • Of the ten SSR loci used, seven are highly recommended for alfalfa genetic diversity analysis, as high genetic variation was detected at these loci. (slu.se)
  • We identified several genetic loci that, individually and in aggregate, substantially affect the risk of development of coronary artery disease. (scienceopen.com)
  • We were forced to examine a substantial number of loci to differentiate between some individuals because of low genetic variation. (psu.edu)
  • We have constructed a genetic linkage map of 17 markers on the long arm of human chromosome 21, including six genes and two anonymous loci with a variable number of tandem repeats. (johnshopkins.edu)
  • In contrast, inter-ocean divergence was highly significant for a majority of loci within each marker class. (wm.edu)
  • Although some microsatellite loci were much more sensitive than scnDNA markers, on average, these differences were not significant, due to the wide range of microsatellite patterns detected. (wm.edu)
  • The rel- that considerable genetic, phenotypic, and pathogenic ative change in Shiga toxin production after induction was diversity exists among these pathogens (6-8). (cdc.gov)
  • Analysis of differentiation (genetic diversity and related relationships) among 22 landrace ( Ficus carica L. sativa ) and 2 wild form ( F. carica L. caprificus ) accessions of fig growing under the same environmental conditions in the Palestinian Fig Collection, Til, Nablus, Palestine, using PCR-based Random Amplified Polymorphic DNA (RAPD) and pomological markers, revealed considerable genetic diversity. (scirp.org)
  • Aljane, F. and Ferchichi, A. (2009) Assessment of Genetic Diversity among Some Southern Tunisian Fig (Ficus carica L.) Cultivars Based on Morphological Descriptors. (scirp.org)
  • Almajali, D., Abdel-Ghani, A.H. and Migdadi, H. (2012) Evaluation of Genetic Diversity among Jordanian Fig Germplasm Accessions by Morphological Traits and ISSR Markers. (scirp.org)
  • The investigation was conducted to assess the association of genetic diversity of parental lines with mean performance of hybrids, mid parent heterosis, better parent heterosis and sca effects. (omicsonline.org)
  • Genetic diversity among the parental lines was determined by RAPD markers and morphological characters. (omicsonline.org)
  • Positive correlation was obtained between molecular marker diversity and F1 mean performance, heterosis over better parent but the value of correlation coefficient was found to be non-significant. (omicsonline.org)
  • High values of among-population genetic diversity were found, which accounted for 71 % of the total genetic variation. (wallonie.be)
  • Genetic diversity represents the heritable variation within and between populations of organisms. (nepjol.info)
  • A better understanding of genetic diversity and its distribution is essential for its conservation and use. (nepjol.info)
  • In this study the genetic diversity analysis was performed in 30 accessions of Centella asiatica (L.) Urb. (nepjol.info)
  • The co-efficient of gene differentiation (Gst) was 1.0000 reflecting the existence of high level of genetic diversity among the isolates. (banglajol.info)
  • The result indicating their genetic diversity has opened new possibility of using the most efficient and more isolates of Trichoderma in the preparation of effective biopesticide. (banglajol.info)
  • In this study, indigenous chicken populations representing seven different areas of northwest Ethiopia were studied using microsatellite markers to determine genetic diversity and variation. (up.ac.za)
  • Microsatellite marker-based genetic diversity analysis and developing synthetic varieties in Alfalfa (Medicago sativa L. (slu.se)
  • The analysis of alfalfa genetic diversity helps to assess the future risk of genetic erosion and helps in the development of sustainable conservation strategies and wise use of the genetic variation in breeding programs. (slu.se)
  • The aim of this Master thesis was to study the genetic diversity of alfalfa grown in Kyrgyzstan and in other countries and determine the genetic relationship using simple sequence repeat (SSR, microsatellite) molecular markers as well as to contribute to the development of synthetic alfalfa varieties for use as forage in Kyrgyzstan. (slu.se)
  • Chrysanthemums have beautiful flowers with high ornamental value and rich genetic diversity. (ashs.org)
  • Molecular technology has been widely used in analyzing genetic relationships and diversity. (ashs.org)
  • Genetic Diversity of Cultivated Millet Varieties ( Pennisetum glaucum (l. (scholarsresearchlibrary.com)
  • Understanding the structure of its genetic diversity and identification on a molecular basis is an important goal for the support, preservation, and success of breeding programs. (scholarsresearchlibrary.com)
  • Genetic diversity of Albanian local goat breeds was estimated previously using microsatellite markers (Hoda et al 2011). (cipav.org.co)
  • In 1999 we obtained genetic material with barbed-wire hair traps to estimate bear population size and genetic diversity at the 329-km 2 Tensas River Tract, Louisiana. (psu.edu)
  • These newly developed SSR markers will be helpful to scientists who are interested in spinach genome diversity and breeding. (iyte.edu.tr)
  • Blue marlin diversity was assessed at mtDNA, scnDNA, microsatellite DNA, and allozyme molecular markers. (wm.edu)
  • ScnDNA and allozyme markers exhibited lower levels of diversity and inter-ocean divergence than mtDNA (average &F\sb{lcub}st{rcub}& = 0.08). (wm.edu)
  • Correlations between diversity and divergence within and among marker classes were non-significant, indicating that difference in mutation rate can not explain the lower nuclear divergence. (wm.edu)
  • The patterns of diversity obtained within and among marker classes is consistent with expected values under migration-drift equilibrium. (wm.edu)
  • these markers are used in plant genotyping, diversity studies, genetic linkage studies, quantitative trait mapping and marker-assisted selection during plant breeding. (iitr.ac.in)
  • Hence, an overview of the genetic diversity and the development of molecular markers are very important for breeding and crop improvement in guar. (iitr.ac.in)
  • In the present study genetic diversity in 19 commercial varieties and 29 landraces of cluster bean belonging to Gujarat, Rajasthan, Haryana and Delhi regions of India were analyzed using 13 RAPD (Randomly Amplified Polymorphic DNA) and 7 1SSR (Inter Simple Sequence Repeat) markers. (iitr.ac.in)
  • The observed number of alleles, effective number of alleles, Nei's genetic diversity, Shannon's information index for landraces and commercial varieties using 13 RAPD markers were found to be 1.872±0.335, 1.589±0.351, 0.333±0.170, and 0.490±0.230, respectively. (iitr.ac.in)
  • Mean coefficient of gene differentiation (Gst) value was 0.148 which indicated that 86.2% of genetic diversity was present within the population. (iitr.ac.in)
  • The observed number of alleles, effective number of alleles, Nei's genetic diversity, Shannon's information index for landraces and commercial varieties using 7 ISSR markers were found to be 1.7812±0.4167, 1.4627±0.3844, 0.267±0.1939, and 0.3988±0.2681, respectively. (iitr.ac.in)
  • Clustering patterns obtained from the combined (pomological and RAPD) markers had higher discriminatory power to discriminate fig landraces than using either pomological or RAPD markers alone. (scirp.org)
  • These results proved the importance of both pomological and RAPD markers to elucidate in part denomination problems and relationships among cultivars. (scirp.org)
  • Khadari, B., Lashermes, P.H. and Kjellberg, F. (1995) RAPD Fingerprints for Identification and Genetic Characterization of Fig (Ficus carica L.) Genotypes. (scirp.org)
  • All the parental lines were screened to detect polymorphism in the form of RAPD markers. (omicsonline.org)
  • PCR-based Random Amplified Polymorphic DNA (RAPD) Marker employing 3 decamer primers produced 29 scorable bands of which all (100%) were polymorphic. (banglajol.info)
  • Authentication of Bulbus Fritillariae Cirrhosae by RAPD-derived DNA markers. (rush.edu)
  • To identify DNA-based genetic polymorphism for constructing a genetic linkage map of catfish, we tested 100 random amplification of polymorphic DNA (RAPD) primers for their utility in identifying genetic polymorphism in catfish. (syr.edu)
  • The RAPD markers were highly reproducible in a size range from 200 to 1500 base pairs (bp). (syr.edu)
  • the average percentage polymorphism for RAPD markers was 87.63. (iitr.ac.in)
  • Genetic variability amongst the isolates was also estimated by RAPD as well as sequencing of ITS region. (bvsalud.org)
  • This prompted the development of gene markers which could identify genetic characteristics that are not readily observable in organisms (such as protein variation). (wikipedia.org)
  • 2000 ). Traditionally, upon the advent of Polymerase Chain Reaction (PCR) technology, genetic variation within wild populations used to be determined either employing a handful of neutral microsatellite markers or assessing mitochondrial DNA sequences (Chapman et al. (nature.com)
  • The somaclonal variation was identified with 2 SSR markers. (wallonie.be)
  • Eighty % of the genetic variation was identified in plants obtained from callus undergoing high osmotic pressure. (wallonie.be)
  • In the present study, we tested the hypothesis that genetic variation in ABCG5 / ABCG8 influences the levels of serum plant sterol (sitosterol) and cholesterol precursor (lathosterol) in Japanese primary hypercholesterolaemic patients ( n =100). (portlandpress.com)
  • A total of 720 individuals of 12 indigenous chicken populations, geographically localized in Southern China were genotyped for 30 microsatellite markers in polymerase chain reaction (PCR) to evaluate the genetic variation and genetic distance between populations. (scialert.net)
  • Heterozygosity was calculated to determine the genetic variation. (scialert.net)
  • The Jaccard similarity coefficient and cluster analysis revealed a significant genetic variation between Kyrgyz alfalfa genotypes, which is significant enough for alfalfa improvement, including the development of synthetic varieties. (slu.se)
  • The introduction of new alfalfa genetic material from countries such as Argentina, Oman, Australia, Iran, Iraq and Norway into Kyrgyzstan is a great opportunity to increase genetic variation in the alfalfa gene pool in the country. (slu.se)
  • Jaccard's coefficient of similarity varied from 0.64 to 0.89, indicating much genetic variation in chrysanthemums. (ashs.org)
  • Hierarchical analysis of molecular variance (AMOVA) revealed that most genetic variation was maintained within populations, with a non-significant fraction attributable to variation among temporal replicates and between locations within oceans. (wm.edu)
  • n = 104) genetic variation within the blue marlin revealed two distinct clades of haplotypes, one of which was present only in the Atlantic (the 'Atlantic clade'), at a frequency of 40% &(F\sb{lcub}st{rcub}& = 0.39). (wm.edu)
  • Genetic alterations in tumors may appear as changes in total DNA content, individual chromosomes, single genes, or gene expression. (nih.gov)
  • Attempts to define molecular markers have used probes of different chromosomal sites, some chosen because of logical associations with hormonal activity, known oncogenes, or tumor-suppressor genes, and some by chance. (nih.gov)
  • To analyse the structuration of mandarin germplasm and the potential interspecific introgressions, 208 accessions were genotyped by the KASPar method, with sixty-seven single nucleotide polymorphism (SNP) markers mined in 27 nuclear genes and in clementine BAC-ends. (ishs.org)
  • Genetic marker, any alteration in a sequence of nucleic acids or other genetic trait that can be readily detected and used to identify individuals, populations, or species or to identify genes involved in inherited disease. (drorawan.com)
  • Genetic testing can reveal changes or alterations in your genes that may cause illness or disease. (drorawan.com)
  • A genetic linkage map is needed to improve efficiency of breeding by marker-assisted selection (MAS), and for identification, isolation and eventual cloning of commercially important genes. (syr.edu)
  • Despite the probable introduction of genes from Minnesota bears in the 1960s, the isolated population at Tensas exhibited characteristics consistent with inbreeding and genetic drift. (psu.edu)
  • We also provide evidence of three of our discovered genetic markers, two of which deliver the first report linking the genes SCAF4 and STMN2 to ALS - an important finding for us. (perroninstitute.org)
  • Antimicrobial resistance occurs through different mechanisms, which include spontaneous (natural) genetic mutations and horizontal transfer of resistant genes through deoxyribonucleic acid (DNA). (who.int)
  • Identifying markers that have the potential to predict tumor behavior is important in breast cancer because of the variability in clinical disease progression. (nih.gov)
  • Genetic variability and divergence rates were tested between stem (paired) and loop (unpaired) regions of secondary structure. (unboundmedicine.com)
  • Further studies, including the effect of environmental factors, genetic composition or possibility of inbreeding, are required to analyze the probable reason for the low variability exists in the species. (nepjol.info)
  • The aim of the present study was to estimate the genetic variability of Muzhake goat breed using microsatellite markers. (cipav.org.co)
  • Assessment of genetic variability and genetic characterization of a breed is very important step for undertaking conservation measurements. (cipav.org.co)
  • It builds on our 2020 publication suggesting genetic regions may hold the key to understanding the variability in ALS patient disease risk and progression. (perroninstitute.org)
  • Guar is a cultivated crop not found in wild conditions and hence its available landraces are the main source of genetic variability. (iitr.ac.in)
  • Fifteen isolates of the pathogen, collected across KP, were studied for variability based on phenotypic and molecular markers. (bvsalud.org)
  • A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites. (wikipedia.org)
  • The molecular screening through microsatellite markers showed low polymorphism (0.019) between the samples analyzed. (nepjol.info)
  • Amplified fragment length polymorphism (AFLP) markers were used to detect the relationships among 12 wild accessions and 62 groundcover chrysanthemum cultivars. (ashs.org)
  • All of these DNA samples were run on a 770,000 single nucleotide polymorphism (770K SNP) genotyping chip and the profiles of the sick cattle were then compared to those that were healthy to see if there were any genetic markers associated with reduced susceptibility to BRDC. (extension.org)
  • A total of 339 microsatellite markers were tested for polymorphism by bulked segregation analysis (BSA) in an F2 population. (smu.ca)
  • Uniparental markers (on mitochondrial or Y chromosomal DNA) are studied for assessing maternal or paternal lineages. (wikipedia.org)
  • Genetic markers have to be easily identifiable, associated with a specific locus, and highly polymorphic, because homozygotes do not provide any information. (wikipedia.org)
  • MCW 154 was the most polymorphic marker across all populations with an average of seven different alleles. (up.ac.za)
  • Polymorphic information content (PIC) was estimated for all markers using the Cervus software (Marshall 1998). (cipav.org.co)
  • The markers produced 58 bands with 57 identified as polymorphic. (iyte.edu.tr)
  • Seven ISSR markers used in the study produced 64 bands out of which 50 were polymorphic. (iitr.ac.in)
  • Genetic markers are employed in genealogical DNA testing for genetic genealogy to determine genetic distance between individuals or populations. (wikipedia.org)
  • Identification of genetic structure within wildlife populations have implications in their conservation and management. (nature.com)
  • Estimated genetic distances varied from 0.83 to 1.67 between populations. (wallonie.be)
  • The topology of phylogenetic trees constructed showed general patterns of relationship and genetic differentiation among the indigenous populations studied, however, both trees from Neighbor-Joining method and Unweighted Pair Group method showed a similar topology. (scialert.net)
  • The results provided evidence of the applicability of microsatellite to determining the genetic relatedness among different Chinese indigenous chicken populations and evaluating of genetic variations. (scialert.net)
  • The RIR commercial chicken breed showed higher genetic distance (lower genetic similarity) with the Ethiopian chicken populations than the South African fowls. (up.ac.za)
  • Based on the phylogenetic tree result, it is concluded that the clustering of the chicken populations in the present study are in accordance with the origin and marketing systems of these native chickens, which indicates that the microsatellite markers used in this study were suitable for the measurement of the genetic biodiversity and relationship of Ethiopian chicken populations. (up.ac.za)
  • Enhanced genetic drift among populations, due to the four-fold lower effective population size of mtDNA, was emphasized as causing the greater mtDNA inter-ocean divergence. (wm.edu)
  • The markers are variations in the inherited DNA code at particular locations along chromosomes. (sciencedaily.com)
  • The presence of selective agent in the medium could explain the observed genetic variations. (wallonie.be)
  • Some Trichoderma isolates were collected from different locations of Bangladesh for evaluating their bioefficiency by determining their genetic variations. (banglajol.info)
  • Genetic markers consist primarily of polymorphisms, which are discontinuous genetic variations that divide individuals of a population into distinct forms (e.g. (drorawan.com)
  • Since the early 1900s, scientists have understood that specific genetic variations (genotypes) translate into specific physical characteristics (phenotypes). (drorawan.com)
  • This paper highlights different examples of novel short structural genetic variations our team has discovered that are associated with ALS disease risk or clinical phenotype. (perroninstitute.org)
  • Of those, we randomly selected 116 subsamples for genetic analysis and used up to 12 microsatellite DNA markers to obtain multilocus genotypes for 58 individuals. (psu.edu)
  • The team combined data from more than 12,000 people with MS for a genome-wide association study, which uses statistics to carefully link genetic variants to individual traits, and recorded the years it took for each study participant to advance from diagnosis to disability, as measured by EDSS. (everydayhealth.com)
  • Over 200K accurate genetic markers reveal your dog's genetic traits, disease detection, genetic ancestry, and behavioral analysis. (chezpuppy.com)
  • The more that addiction is seen as having biological roots and origins in genetic traits that are inherited through families or amplified by drug taking, the better treatment options and public policy around drugs and drug users can be, she hopes. (technologynetworks.com)
  • Raised for dozens of generations in the lab of senior author Huda Akil, Ph.D., at the U-M Molecular and Behavioral Neuroscience Institute under carefully controlled conditions, the two breeds act as a way to study the effects of genetic and inherited traits on addiction-related behaviors. (technologynetworks.com)
  • The SNP assays are finding genomic regions associated with BRDC susceptibility, suggesting that genetic progress in these traits could be made by including the specific SNP markers that are indicators of BRDC disease risk in national cattle genetic evaluations. (extension.org)
  • Among all accessions, genetic relationship was the most relevant factor in AFLP-marker clustering, whereas petal type was also informative. (ashs.org)
  • In this study we screened 176 spinach world collection germplasm accessions with 15 known SSR markers. (iyte.edu.tr)
  • The maximum genetic dissimilarity of spinach accessions was 0.551 and minimum was 0.019. (iyte.edu.tr)
  • They also created a tool that will allow public health laboratories to analyze their own Ng samples for genomic markers of antimicrobial resistance. (cdc.gov)
  • Identification of fluorescence in situ hybridization assay markers for prediction of disease progression in prostate cancer patients on active surveillance. (rush.edu)
  • SYDNEY, Oct. 24 (Xinhua) -- A global medical collaboration involving Australian researchers has discovered 72 genetic variants that put women at higher risk of breast cancer. (xinhuanet.com)
  • We know that breast cancer is caused by complex interactions between these genetic variants and our environment, but these newly discovered markers bring the number of known variants associated with breast cancer to around 180. (xinhuanet.com)
  • Our hope is that in future we will be able to test for these genetic variants in order to inform preventative approaches and treatment for women who may be at a higher risk of breast cancer. (xinhuanet.com)
  • To identify genetic variants influencing plasma lipid concentrations, we first used genotype imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals and comprising 6,068 individuals specific to our study (1,874 individuals from the FUSION study of type 2 diabetes and 4,184 individuals from the SardiNIA study of aging-associated variables) and 2,758 individuals from the Diabetes Genetics Initiative, reported in a companion study in this issue. (scienceopen.com)
  • First author for the expert opinion article ' Short structural variants as informative genetic markers for ALS disease risk and progression ' was PhD candidate Frances Theunissen from the Motor Neurone Disease Genetics and Therapeutics Research group at the Perron Institute and the Centre for Molecular Medicine and Innovative Therapeutics at Murdoch University. (perroninstitute.org)
  • The aim is to produce an attenuated virus that incorporates the key immunizing antigens and antigenic determinants of circulating wild influenzaviruses but retains the stable genetic and phenotypic characteristics of the attenuated donor strain when given to susceptible individuals on a wide scale. (who.int)
  • In some cases, a lineage or group of lineages with similar genetic changes, may be designated by the World Health Organization (WHO) or the U.S. SARS-CoV-2 Interagency Group (SIG) as a Variant of Interest (VOI), Variant of Concern (VOC), Variant of High Consequence (VOHC) or Variant Being Monitored (VBM) due to shared attributes and characteristics that may require public health action. (cdc.gov)
  • These SNP markers were employed for the study of 208 genotypes comprised of 169 mandarin-like genotypes and 39 genotypes belonging to ancestral taxa. (ishs.org)
  • The Ethiopian chicken population Gassay/Farta had the highest number of alleles per locus (10) for microsatellite marker MCW 158. (up.ac.za)
  • Nov. 1, 2023 As people age, the DNA in their cells begins to accumulate genetic mutations. (sciencedaily.com)
  • Foulkes previously discovered that loss-of-function mutations in the chromatin remodeling gene SMARCA4 is ubiquitous in SCCOHT in the course of investigating the genetic roots of rare familial ovarian tumors. (cancernetwork.com)
  • These flaws are referred to as genetic mutations. (drorawan.com)
  • Viruses like SARS-CoV-2 continuously evolve as changes in the genetic code (caused by genetic mutations or viral recombination) occur during replication of the genome. (cdc.gov)
  • A variant is a viral genome (genetic code) that may contain one or more mutations. (cdc.gov)
  • With a WGS file upload and a few clicks of a mouse, public health scientists are minutes away from an easy-to-read report that summarizes information about the isolates in question, including sequence type and genetic mutations associated with reduced antibiotic susceptibility - the information they need to monitor locally circulating strains and to detect emerging resistant gonorrhea and potential transmission clusters. (cdc.gov)
  • Waltham, MA-Interleukin Genetics Inc. has received a U.S. patent for a method that uses specific genetic markers to identify people with diabetes who are at an increased risk of retinopathy. (ophthalmologytimes.com)
  • The vulnerability of individuals to becoming "hooked" on drugs may involve specific genetic factors - both inherited and influenced by drug use. (technologynetworks.com)
  • The road to answering these questions may have a lot to do with specific genetic factors that vary from individual to individual, a new study in rats suggests. (technologynetworks.com)
  • Average genetic distance ranged from 0.6% to 100%, indicating a diverse genetic gap among the isolates. (bvsalud.org)
  • Understanding how genetic differences in individuals contribute to their susceptibility to CVDs can help guide practitioners to give the best advice to achieve a favorable outcome for the patient. (scienceopen.com)
  • Genetic-based, differential susceptibility to exposure to combined organophosphate and increased glucocorticoid in a mouse model of Gulf War Illness. (cdc.gov)
  • The presence of different alleles due to a distorted segregation at the genetic markers is indicative of the difference between selected and non-selected livestock. (wikipedia.org)
  • Genetic markers play a key role in genetic mapping, specifically in identifying the positions of different alleles that are located close to one another on the same chromosome and tend to be inherited together. (drorawan.com)
  • Furthermore, molecular genetic markers were used to resolve the issue of natural transmission, the breed of origin (phylogenetics), and the age of the canine tumor. (wikipedia.org)
  • Accurately inferring population genetic structure requires whole-genome data across the geographical range of the species, which can be resource-intensive. (nature.com)
  • A cheaper strategy is to employ a subset of markers that can efficiently recapitulate the population genetic structure inferred by the whole genome data. (nature.com)
  • These 49 SNPs were sufficient to recapitulate the population genetic structure obtained from the whole genome data. (nature.com)
  • 2020 ). Unravelling population structure involves the use of multiple markers from across the genome (Pritchard et al. (nature.com)
  • 2009 ). With the advancement in next-generation sequencing (NGS) techniques several thousand to millions of markers across the genome have become available for population genetic analysis, even for non-model organisms (Khan and Tyagi 2021 ). (nature.com)
  • Sequencing of Restriction site-associated DNA (RAD) markers (RADseq) has made it increasingly possible to perform NGS without having a reference genome in hand (Catchen et al. (nature.com)
  • 2019 ). Consequently, resolving the population structure of most wild and endangered fauna with genome-wide SNP markers has been challenging. (nature.com)
  • The genetic analysis is by far the largest genome wide association study to date on this condition. (incitasecurity.com)
  • Microsatellites are markers of choice since they are simple to analyze, highly abundant and highly distributed in the genome. (cipav.org.co)
  • Universal nuclear genome via IIIumina MiSeq technology and genome assembly was performed to develop new spinach-specific SSR markers. (iyte.edu.tr)
  • A mutation refers to a single change in a virus's genome (genetic code). (cdc.gov)
  • We then performed genome-wide mapping of the IL1beta results and found a significant marker (quantitative trait locus) on distal chromosome 7. (cdc.gov)
  • The future of Crohn's and Colitis treatment is personalized medicine, so the identification of a genetic marker that explains why anti-TNF drugs don't work for some people with Crohn's is highly significant. (news-medical.net)
  • Restriction endonuclease markers were developed to distinguish among the species at all life history stages, allowing rapid identification in areas of sympatric distribution. (unboundmedicine.com)
  • Ewens-Watterson test was performed to test the neutrality for microsatellite markers, using the algorithm by Manly (2007) using 1000 simulated samples and implemented in Popgene software package (Yeh et al 1999). (cipav.org.co)
  • Chromosomal studies could provide a more precise tool for localizing genetic damage, but there is little cytogenetic information about primary breast cancers, no convincing evidence has emerged to target locations in the karyotype that appear specifically altered, and many primary and cultured breast cancers contain cells that appear chromosomally normal. (nih.gov)
  • A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. (wikipedia.org)
  • For many years, gene mapping was limited to identifying organisms by traditional phenotypes markers. (wikipedia.org)
  • Genetic markers can be used to study the relationship between an inherited disease and its genetic cause (for example, a particular mutation of a gene that results in a defective protein). (wikipedia.org)
  • This property enables the use of a marker, which can then be used to determine the precise inheritance pattern of the gene that has not yet been exactly localized. (wikipedia.org)
  • Marker gene Molecular marker DNA marking Eukaryotic chromosome fine structure Repeated sequence (DNA) Benjamin A. Pierce (2013-12-27). (wikipedia.org)
  • Homozygous loss of band 9p21, the site for the tumor suppressor gene P16 , is a known early genetic event in the development of papillary carcinoma and urothelial carcinoma in situ (CIS). (medscape.com)
  • In the present work we studied the inheritance of the three grains trait and identified simple sequence repeats (SSR) markers linked to the Mg gene. (smu.ca)
  • Six microsatellite markers, Xcfd233, Xgdm6, Xgdm87, Xgwm311, Xgwm349 and Xgwm539, on chromosome 2DL, were linked to Mg. Using the CS 2D deletion lines, Mg gene was localized to the distal region of chromosome 2DL. (smu.ca)
  • The microsatellite markers identified in this study have the potential for further mapping and map-based cloning of the gene. (smu.ca)
  • An odds ratio will be equal to 1 if there is no connection between the SNP to the trait or genetic condition. (thetech.org)
  • A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event. (usda.gov)
  • Different genetic patterns controlling this trait have been reported. (smu.ca)
  • Generally co-dominant markers are more informative than the dominant markers. (wikipedia.org)
  • Such ancestry informative markers (AIMs), have rarely been developed for endangered species such as tigers utilizing single nucleotide polymorphisms (SNPs). (nature.com)
  • The set of used markers was highly informative. (cipav.org.co)
  • Genotyping, a process used to determine genetic differences within an individual's DNA, can provide doctors with relevant information to identify individuals who are at high risk of developing CVDs. (scienceopen.com)
  • Scientists have discovered a genetic variant that appears to predict faster symptom progression in people with multiple sclerosis. (everydayhealth.com)
  • For the first time ever, researchers have identified a genetic variant that may help predict faster symptom progression - and thus, more rapid declines in mobility and independence - in people with multiple sclerosis (MS) . (everydayhealth.com)
  • The genetic variant may also help explain why people with the condition experience progression differently, with some needing a wheelchair within 10 years of diagnosis, while others continue to remain able to walk without assistive devices, according to Baranzini. (everydayhealth.com)
  • The markers we've identified could also help with patient prognosis and provide information on disease progression and response to drugs. (perroninstitute.org)
  • Marker in Isolates (PFGE). (cdc.gov)
  • The Unweighted Pair Group Method of Arithmetic Means (UPGMA) dendrogram constructed from Nei's (1972) genetic distance produced 2 main clusters (16 isolates in cluster 1 and 19 isolates in cluster 2). (banglajol.info)
  • Maximum genetic distance was found between isolates Bm9 and Bm10 as well as Bm2 and Bm8. (bvsalud.org)
  • Conversely, isolates Bm13 and Bm15 were at minimum genetic distance. (bvsalud.org)
  • The discovery of these markers -- along with four that were previously identified is important for several reasons, said Brian Wolpin, MD, MPH, first author of the report published online by Nature Genetics . (sciencedaily.com)
  • This work helps us to understand why some women are more at risk of developing breast cancer than others and what genetic markers we should be looking for in order to assess that risk," the institute quoted Professor Georgia Chenevix-Trench, the coordinator of its genetics and computational biology department, as saying. (xinhuanet.com)
  • The D-loop minisatellite results showed overlapping ranges of fragment sizes and suggested heteroplasmy, a result that nullify the use of this region for the development of breed diagnostic markers. (fao.org)
  • Recombination in females was approximately twice that in males between proximal markers. (johnshopkins.edu)
  • With the aid of genetic markers, researchers were able to provide conclusive evidence that the cancerous tumor cell evolved into a transmissible parasite. (wikipedia.org)
  • The researchers looked in rats' brains for the genetic instructions needed to make a key "pleasure receptor", called D2, that allows brain cells to receive signals sent by the brain chemical dopamine - or cocaine. (technologynetworks.com)
  • Autosomal markers are used for all ancestry. (wikipedia.org)
  • 3. DNA My dog: This test supplies a thorough analysis of over 150 breeds, as well as details on genetic health risks, provider standing for sure conditions, and also ancestry info. (chezpuppy.com)
  • Non-medical uses of genetic testing include paternity test (used to identify inheritance patterns between individuals), genealogy testing (to determine ancestry or heritage), or forensic testing (to identify an individual for legal purposes). (drorawan.com)
  • Typology of varieties by the UPGMA method using the SAHN procedure and the Principal Coordinate Analysis (PCoA) based on genetic distances showed the existence of three major genetic groups. (scholarsresearchlibrary.com)
  • 16% of RR tumors showing genetic amplification (P = 0.02). (nih.gov)
  • Genetic distance calibration with the fossil record estimated the pairwise sequence divergence as 0. (unboundmedicine.com)
  • AFLP technology could be very efficient for discriminating species of chrysanthemum and its related genera and reconstruct their genetic relatedness. (ashs.org)
  • Disease Resistance in Crop Plants : Molecular, Genetic and Genomic Perspectives. (wikipedia.org)
  • Future scientific research should focus on further validating these genetic resistance markers. (lu.se)
  • These data help CDC track genetic markers of antibiotic resistance, and this information is then used to develop evidence-based treatment guidelines. (cdc.gov)
  • Assessing the population genetic structure of wild species is important for their management (Wultsch et al. (nature.com)
  • A large DNA analysis of people with and without pancreatic cancer has identified several new genetic markers that signal increased risk of developing the highly lethal disease, report scientists from Dana-Farber Cancer Institute. (sciencedaily.com)
  • Scientists have discovered new genetic areas linked to an increased risk of glaucoma - the leading cause of irreversible blindness worldwide. (incitasecurity.com)
  • In this study, 42 varieties of millet collected in four agro-ecological zones of Benin already grouped into 3 morphological classes were evaluated using 12 microsatellite markers (SSRs). (scholarsresearchlibrary.com)
  • The risks linked to each SNP or marker were largely independent and additive, so that they may have utility in future attempts to identify individuals in the general population at higher risk for pancreatic cancer. (sciencedaily.com)
  • Data collection from the feedlot beef cattle population is complete, and a similar analysis is being performed to identify genetic markers in this population. (extension.org)
  • We discuss how the application of genetic markers to clinical trials could help to better identify ALS patient sub-groups that may progress in a similar way," she said. (perroninstitute.org)
  • Overall, genetic urinary biomarkers are a very heterogeneous group of tests that currently cannot replace cystoscopy and cytology, which remain the gold standard for surveillance of non-muscle-invasive bladder cancer (NMIBC). (medscape.com)
  • Results: Thirteen unique biomarkers, three genetic signatures, one specific pathway, and two combinations of two or four biomarkers were identified. (lu.se)
  • In this study, to accumulate further evidence for the importance of genetic factors in pathogenesis of inflammatory bowel disease, sera of patients with inflammatory bowel disease and primary sclerosing cholangitis and their unaffected family members were tested for pANCA. (nih.gov)
  • The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment. (news-medical.net)
  • Previous studies have identified genetic factors that determine the risk for developing MS , most of which were related to immune function, [but] this study shows that different genetic factors determine disease outcome, namely factors that affect the nervous system's ability to compensate for damage," notes Jeffrey Cohen, MD , a neurologist and director of the Cleveland Clinic's Mellen Center for MS Treatment . (everydayhealth.com)
  • These genetic factors could be used to predict outcome - or prognosis - to help determine how aggressive disease therapy needs to be," adds Dr. Cohen, who wasn't part of the Nature study. (everydayhealth.com)
  • The study of genetic aberrations commonly associated with urothelial carcinoma provides a more objective assessment for diagnosing and detecting recurrent disease. (medscape.com)
  • A study by Sokolova et al of 9 genetic markers for detecting urothelial carcinoma showed that polysomy of chromosomes 3, 7, and 17 and deletion of 9p21 were the most sensitive and specific markers, detecting 95% of recurrent urothelial carcinomas. (medscape.com)
  • Genetic characterization of native breeds is very important in conservation strategy designing. (cipav.org.co)
  • Out of them, 32 polymorphisms were potential Iberian markers, 10 potential Duroc markers and 16 potential wild boar markers. (fao.org)