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  • quantitative trai
  • More specifically, the invention includes a method for breeding soybean plants containing quantitative trait loci that are associated with resistance to Asian Soybean Rust (ASR), a fungal disease associated with Phakopsora. (google.com.au)
  • The invention further includes germplasm and the use of germplasm containing quantitative trait loci (QTL) conferring disease resistance for introgression into elite germplasm in a breeding program for resistance to ASR. (google.com.au)
  • The observation that variants regulating gene expression (expression quantitative trait loci, eQTL) are at a high frequency among SNPs associated with complex traits has made the genome-wide characterization of gene expression an important tool in genetic mapping studies of such traits. (csuca.org)
  • We then combined the genomic confidence intervals of these loci with expression quantitative trait loci from bone and hypothalamus in the same intercross. (diva-portal.org)
  • identify
  • The study design enabled us to comprehensively reconstruct the genetic regulatory network in these families, provide estimates of heritability, identify eQTL, evaluate missing heritability for the eQTL, and quantify the number of different alleles contributing to any given locus. (csuca.org)
  • Overlaps between egg loci and expression loci, and trait-gene expression correlations identify 29 candidates from bone and five from hypothalamus. (diva-portal.org)
  • present
  • Interpretation Despite the small sample size for a genome-wide association study, and acknowledging the potential biases from ascertaining samples from multiple locations, we present the most comprehensive and well powered genetic study in dementia with Lewy bodies so far. (nottingham.ac.uk)
  • Rare
  • Tuberous sclerosis complex (TSC) is a rare multisystem genetic disease that causes benign tumors to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs, and skin. (wikipedia.org)
  • studies
  • These studies began in the 70's and studied the impact of perinatal problems, genetic variants, sexual abuse and other adverse exposures on psychological problems in childhood and later in adulthood. (wikipedia.org)
  • This study was significant as it was one of the first studies to use exome array genotyping, an alternative to genetic sequencing. (wikipedia.org)
  • population
  • Stem cell variability is often caused by epigenetic changes, but can also result from clonal evolution of the CSC population where advantageous genetic mutations can accumulate in CSCs and their progeny (see below). (wikipedia.org)
  • cells
  • This provides a pathway for genetic information to be exchanged between cells, and could provide a mechanism for the transfer of antibiotic resistance between organisms. (wikipedia.org)
  • Multiple types of heterogeneity have been observed between tumour cells, stemming from both genetic and non-genetic variability. (wikipedia.org)
  • variants
  • Altered DNA methylation at various CpG sites was associated with exposure to mercury, lead or BPA, providing candidates to be investigated using a larger study sample, as the results may reflect an independently associated predictor (e.g. socioeconomic status, diet, genetic variants, altered blood cell composition). (pubmedcentralcanada.ca)
  • drift
  • Its high frequency among Kosovo Albanians (46%) is most likely a consequence of genetic drift. (wikipedia.org)
  • Although its frequency is very high in Kosovo Albanians (46%) and Macedonian Romani (30%), this phenomenon is of a focal rather than a clinal nature, most likely being a consequence of genetic drift. (wikipedia.org)
  • protein
  • The key of our method is the systematic purification of several tagged components of the protein complex in multiple genetic deletion strains, which serve to compromise the integrity of the complex. (embopress.org)
  • An increase in copy number is useful for genetic engineering applications to increase the production yield of recombinant protein. (wikipedia.org)
  • Replication
  • Minimal plasmids such as PFF1 are useful for studying the basic mechanisms of plasmid replication and copy number regulation, as there are less superfluous genetic elements which might affect the processes being studied. (wikipedia.org)
  • Humans
  • The population divergence of modern humans from the Denisovan/Neanderthal lineage is more recent, between 170,000 and 700,000 years according to a more recent - and much deeper -sequencing of the above Denisovan fossil , so many loci will have persisted at fluctuating frequencies in all three lineages. (scienceblogs.com)
  • control
  • For this purpose, we examined affected patients' perception of tinnitus as an illness, comorbidity, scores on locus of control, length of time since onset of tinnitus, pitch and loudness of tinnitus sounds, and depression. (neurootology.org)
  • single
  • The RK2 Plasmid is a broad-host-range plasmid belonging to the incP incompatibility group It is notable for its ability to replicate in a wide variety of single-celled organisms, which makes it suitable as a genetic engineering tool. (wikipedia.org)
  • time
  • His collaborative poem with Robert Frazier, "Return to the Mutant Rain Forest," received first place in the 2006 Locus Online Poetry Poll for Best All-Time Science Fiction, Fantasy, or Horror Poem. (wikipedia.org)
  • similar
  • It remained to characterize the e J allele whose phenotypic effect is similar to the Orange and Sex-linked yellow loci of cat and Syrian hamster. (biomedcentral.com)
  • responsible
  • The genetic relationships described here will aid in positional cloning efforts to identify the genes responsible for the disparate phenotypes associated with the sy locus. (jax.org)
  • serve
  • Small non-coding RNAs may serve as a potential mechanism for stress-related genetic changes in offspring. (wikipedia.org)