• Thus to use the phrase "of an existing or previously existing human being" to refer to the product of human cloning would not be a scientifically accurate description of the cloned or genetically engineered human embryo -- thus creating yet another loophole in the bill or treaty. (lifeissues.net)
  • After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
  • It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
  • Next, oocytes with the patient's genetic material were allowed to grow to the blastocyst stage, an early stage of embryo development. (scienceblog.com)
  • … "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
  • … "human clone" means an embryo that, as a result of the manipulation of human reproductive material or an in vitro embryo, contains a diploid set of chromosomes obtained from a single - living or deceased - human being, fetus, or embryo. (hinxtongroup.org)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
  • Thus, while Ramsey agreed that there is a human being present immediately at fertilization, he did not agree that it was also a human embryo or a human person - the classic "pre-embryo" argument. (lifeissues.net)
  • The human embryo did not begin until after 14-days, thus the above quote from Saunders would not apply. (lifeissues.net)
  • Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
  • 6. " ... any living human embryo has the inherent 'potential' to develop into a healthy baby . (lifeissues.net)
  • Originally the relevant philosophical term was "potency" (or inherent power or capacity conveyed by a specific nature) was used to apply to an already existing substance - such as a new living human embryo. (lifeissues.net)
  • In that sense, the human embryo would not be even a human being yet, much less a human person. (lifeissues.net)
  • Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
  • That is, it would be acknowledging that the human embryo and the human " baby " are the same human being and human person throughout all of his/her development. (lifeissues.net)
  • On the other hand, if by "potential" one means that the human embryo is not a human being or human person yet , but might be later once it has been born (i.e., a "baby"), then that statement is both scientifically and philosophically incorrect. (lifeissues.net)
  • Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
  • Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
  • The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)
  • The fusion ultimately gives rise to a microscopic embryo, from which embryonic stem cells can theoretically be derived. (the-scientist.com)
  • In the best case, an early embryo consisting of a few cells may form, but these are not capable of giving rise to human life, nor hESCs for therapeutic purposes. (the-scientist.com)
  • The resulting clone developed into a microscopic embryo, which survived long enough for pluripotent stem cell lines to be derived. (the-scientist.com)
  • During the process of harvesting embryotic stem cells, the embryo is destroyed. (healthline.com)
  • Opponents believe that an embryo is a living human being. (healthline.com)
  • To be sure, viewed through the lens of Jewish law, even the embryo outside the womb is human life. (jewishvaluesonline.org)
  • If implantation of the embryo is not contemplated, embryonic human life is static. (jewishvaluesonline.org)
  • In the first 4 - 5 days after fertilization, the early-stage embryo (or blastocyst) is comprised of about 150 cells, within which there is a region called the Inner Cell Mass containing the stem cells. (jewishvaluesonline.org)
  • The creation of an embryo by nuclear transfer is a human being whose right to continued life should be respected. (cmq.org.uk)
  • The intention of Parliament in drawing up the 1990 Act was to totally ban cloning which was then foreseen as transferring a nucleus into an enucleated embryo. (cmq.org.uk)
  • Secondly, widening the scope of research further establishes the human embryo as a mere commodity for use as a research animal and moves away from Dame Warnock's assertion that the embryo deserves special respect. (cmq.org.uk)
  • Britain is almost isolated in Europe in its failure to afford the human embryo any meaningful status, as attested by the huge number of embryos produced and destroyed. (cmq.org.uk)
  • On the topic of cloning we should set an example by outlawing it in all its forms, cloned babies and so called 'therapeutic cloning' (which is a misnomer as at this stage no therapeutic benefit will result from the cloned embryo). (cmq.org.uk)
  • The predominant bioethical concern arising from this technology is that the blastocyt-stage embryo must be destroyed in the process of isolating and separating the embryonic stem cells from the inner mass region of the pre-embryo. (jcpa.org)
  • The destruction of the pre-embryo has been the critical issue in the U.S. behind imposing limits on federal government-sponsored research in embryonic stem cells. (jcpa.org)
  • Most human embryos reproduced by most human cloning techniques would actually be genetically unique -- i.e., having never existed before. (lifeissues.net)
  • Human cloning involves creating embryos with the intent of implanting them in women to produce children. (boloji.com)
  • The bill also applies Federal ethical regulations on human subject research and outlaws the transfer of cloned embryos to a woman's uterus or to any artificial womb. (boloji.com)
  • At the same time, the statement calls for a five-year moratorium on the use of cloning to create human embryos for research purposes. (boloji.com)
  • While supporting research that would help to determine whether stem cells have therapeutic effects, they point out that those adult stem cells, umbilical cord stem cells, and embryonic stem cells not derived from embryos created for research can be used. (boloji.com)
  • Particularly valuable animals could be cloned from adult cells without the uncertainties of crossing them with other animals or tinkering with embryos. (newscientist.com)
  • Today, this technique continues to form the foundation for research on mammalian embryos, including technologies such as transgenic engineering, embryonic stem cell therapy, human in vitro fertilization, mammalian cloning, and knockout engineering. (avma.org)
  • From there, Dr. Brinster became interested in modifying the development of animals and their germ lines, and he went on to become the first person to show that it was possible to colonize a mouse blastocyst with stem cells from older embryos. (avma.org)
  • 1] Therapeutic cloning, on the other hand, creates human embryos merely as a source of embryonic stem cells. (reasons.org)
  • Tragically, however, in order to harvest stem cells from human embryos, the embryos must be destroyed. (reasons.org)
  • Crudely put, therapeutic cloning looks to generate human embryos solely for the body parts they can provide. (reasons.org)
  • Recent and ongoing research suggests an alternative approach that can achieve the same goal (repair of damaged or diseased organs) without destroying human embryos. (reasons.org)
  • This means that hundreds of human embryos would die to achieve a single live human clone birth. (reasons.org)
  • A couple of studies show some success in generating early microscopic embryos, but this [study] is the first successful pluripotent stem cell line," said Daley. (the-scientist.com)
  • This could help researchers identify abnormalities in iPSC differentiation, correct them, and develop pluripotent stem cells that don't harbor tumorigenic qualities and do not require the use of human embryos. (the-scientist.com)
  • Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
  • TORONTO (CNS) - The international scientific body governing stem cell research is abandoning the absolute 14-day limit on culturing human embryos in the laboratory, putting pressure on Canada's law prohibiting the practice. (thetablet.org)
  • On May 26, the International Society for Stem Cell Research said it was relaxing the 14-day rule, which prohibited experiments on human embryos past 14 days of development in the lab. (thetablet.org)
  • Rather than replace or extend the limit, the ISSCR now believes studies proposing to grow human embryos beyond two weeks should be considered on a case-by-case basis, subject to several phases of review. (thetablet.org)
  • Recent experimentation that has cultured lab-grown monkey embryos for up to 20 days and the possibility of creating human-monkey chimeras - beings that contain genetic codes from two different species - has further pushed the envelope on embryonic stem cell research. (thetablet.org)
  • First, while stem-cell experimentation could involve the creation of embryos with the express purpose of destroying them, this is not the only means available for obtaining embryos. (jewishvaluesonline.org)
  • Thus, there is broad halakhic (Jewish legal) agreement that stem cell research is permitted on "excess" embryos. (jewishvaluesonline.org)
  • Most (but not all) authorities would forbid the creation of embryos with the express purpose of killing them in the pursuit of stem cell research. (jewishvaluesonline.org)
  • The controversy over stem cell research is focused specifically on the use of stem cells taken from embryos. (jewishvaluesonline.org)
  • Furthermore most scientists agree that research cloning for medical research is not needed as a source of embryonic stem cells these can be obtained from embryos generated by in vitro fertilization. (freebooksummary.com)
  • Most of the differences between Britain and other countries are due to the lowly status that is afforded the human embryos in this country. (cmq.org.uk)
  • Stem cells from cord blood or adult tissues do not give rise to the same moral considerations as those derived from embryos or cloned embryos or aborted foetuses. (cmq.org.uk)
  • To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
  • In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
  • Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
  • A blastocyst (cloned or not), because it lacks any trace of a nervous system, has no capacity for suffering or conscious experience in any form - the special properties that, in our view, spell the difference between biological tissue and a human life worthy of respect and rights. (wikiquote.org)
  • Stem cells were then derived from the inner cell mass of the blastocyst. (scienceblog.com)
  • The Korean researchers who performed this stem cell research improved upon their protocols that yielded the first embryonic stem cell line from a cloned human blastocyst. (scienceblog.com)
  • Moreover, Dr. Brinster first demonstrated that teratocarcinoma cells could combine with blastocyst cells to form adult chimeric mice, establishing the feasibility of this approach to change the genetic character of mice. (avma.org)
  • Up to 14 days a human blastocyst - the earliest stage of fetal development - consists almost entirely of pluripotent cells, which are those that could develop into the constitutive elements of any organ in the human body. (thetablet.org)
  • Most researchers obtain embryonic stem cells from the inner mass of a blastocyst, an embryonic stage when a fertilized egg has divided into 128 cells. (jcpa.org)
  • The stem cells derived from the inner mass of a blastocyst lack the ability to form a fetus when implanted into a woman, but are self-renewing and can be maintained for long periods of time in the laboratory as undifferentiated stem cells. (jcpa.org)
  • These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
  • XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • introduction of specific genetic material from a donor into a host organism. (freeonlineresearchpapers.com)
  • The related concept of Longevity Determination , however, is the result of a species-specific genomic expression during early development that positions the somatic tissues of an organism to survive long after its reproductive period has been completed. (agemed.org)
  • This argument I see it very insufficient because cloned organs can have some defects and cause some damage in a person's body and organism if the procedure is not well done. (freebooksummary.com)
  • Stem cell research is, in part, a quest to understand cellular differentiation, the process by which a human being develops from one fertilized cell into a multicellular organism composed of over 200 different cell types - for example muscle, nerve, blood cell, or kidney. (jcpa.org)
  • Progenitors are obtained by so-called direct reprogramming or directed differentiation and are also called induced somatic stem cells. (wikipedia.org)
  • In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. (scienceblog.com)
  • The term stem cell can be defined by two very important qualities: the cell has the ability to self-renew and, in a more general sense, the cell has not completed differentiation into its final state. (thefutureofthings.com)
  • The principles of stem cell development and differentiation should be researched in animals. (cmq.org.uk)
  • Cellular differentiation begins with the fertilized egg which serves as the identifying characteristic of an embryonic stem cell. (jcpa.org)
  • The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
  • Before patient-specific stem cells can potentially be used in the clinic, a variety of issues must be addressed, the researchers emphasized. (scienceblog.com)
  • From the 185 donated oocytes, endowed with the genetic material from a different person (or in one case, the same person), the researchers report development of 31 hollow balls of cells called "human nuclear-transfer blastocysts. (scienceblog.com)
  • The researchers generated these stem cell lines ten times more efficiently than in their 2004 Science study, using improved laboratory methods. (scienceblog.com)
  • For each clone, the Roslin researchers combine material from two sources. (newscientist.com)
  • Next, the researchers take cells containing donor genetic material. (newscientist.com)
  • The researchers then used these cells as the source of genetic material to clone pigs with organs that lacked the sugar groups responsible for HAR. (reasons.org)
  • But Takashi Shinohara, a reproductive biologist at Kyoto University in Japan, is among researchers who have doubts about the work: he notes that scientists have struggled to replicate several previous claims that sperm can be made in a dish. (scientificamerican.com)
  • Through moving findings between monkey cells and human cells, the researchers were able to develop a successful method. (ohsu.edu)
  • Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)
  • While the Catholic Church has maintained opposition to in vitro fertilization and experimentation on the developing human fetus, what limits should be placed on science and how to enforce them have been debated since culturing humans in labs became possible in the 1970s. (thetablet.org)
  • generated haploid male gametes from mouse embryonic stem cells that can produce viable and fertile offspring, demonstrating functional reproduction of meiosis in vitro. (scientificamerican.com)
  • is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)
  • There is no way that human cloning could be developed without unethical mass experimentation on women and children,' they said. (boloji.com)
  • It has not yet been " ensouled " - and so is not yet a " person " - i.e., a human subject to be protected from abuse in experimentation. (lifeissues.net)
  • The Vatican document "Dignitas Personae" ("The Dignity of a Person") warns that certain recent developments in stem-cell research, gene therapy and embryonic experimentation violate moral principles and reflect an attempt by man to "take the place of his Creator. (thetablet.org)
  • A few years ago, in an article in the The Times of London newspaper, the author, Michael Gove, made the following statement: "Embryonic stem-cell experimentation involves not just the destruction of human life but the creation of life with the specific intent to destroy it. (jewishvaluesonline.org)
  • Second, Michael Gove holds that embryonic experimentation represents the destruction of human life. (jewishvaluesonline.org)
  • Some in the biomedical community hope to develop techniques to generate replacement tissues from these embryonic stem cells. (reasons.org)
  • One such approach, called "xenotransplantation" (the transplantation of living cells, tissues, and organs from one species to another species), turns to pigs as a source of organs for human transplants. (reasons.org)
  • The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
  • These stem cells come from developed organs and tissues in the body. (healthline.com)
  • In the normal course of gestation, these cells will divide and split off from one another to become every cell in the human body, forming the various organs and tissues. (jewishvaluesonline.org)
  • Similarly, when the fertilized egg divides from two cells into four cells, each of these four cells has the potential to individually form a human fetus. (jcpa.org)
  • Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
  • The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
  • 2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
  • 3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
  • 7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
  • 3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
  • Scientists have the wrong and ambitious idea that they can create a new human being by themselves, but the truth is that the only one who can do that is God.If people do not stop thinking about cloning human beings at this time, in the future the consequences will be worse because it is not going to be use only for positive things but only negative things. (freebooksummary.com)
  • Should the Cloning of Human Beings be Prohibited? (freebooksummary.com)
  • human beings have developed innovative technologies to treat and cure disease, to enhance human living conditions, and to protect or improve the environment. (jcpa.org)
  • Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
  • Dolly the sheep was cloned in 1996. (thetablet.org)
  • The Government has now used a legal loophole to allow cloning, relying on the 'defective' legal definition in that the technique (as in 'Dolly') used an unfertilised ovum. (cmq.org.uk)
  • There were an alarming number of miscarriages and abnormalities with the technique," says Roger Gosden, a reproductive biologist at the Leeds General Infirmary. (newscientist.com)
  • In 1966, his final year at Nottingham, he received a scholarship to conduct research for a summer under English biologist Ernest John Christopher Polge in the Unit of Reproductive Physiology and Biochemistry, then a division of the Agricultural Research Council at the University of Cambridge. (mathisfunforum.com)
  • Now, Xiao-Yang Zhao, a development biologist at the Southern Medical University in Guangzhou, and Qi Zhou, a cloning specialist and stem-cell biologist at the Institute of Zoology in Beijing, along with colleagues from Nanjing Medical University, say that they have trumped Saitou's work by carrying out more of the process in a dish. (scientificamerican.com)
  • The fact that the resulting cell could be injected into an egg and produce a viable animal is a stringent test," says Allan Spradling, a reproductive biologist at the Carnegie Institution for Science in Baltimore, Maryland. (scientificamerican.com)
  • For his pioneering work in the field of genetics, Dr. Ralph L. Brinster, the Richard King Mellon Professor of Reproductive Physiology at the University of Pennsylvania School of Veterinary Medicine, has been awarded the 2010 National Medal of Science. (avma.org)
  • Pig organ size and physiology are comparable to that of humans. (reasons.org)
  • AN - check the tag INFANT HN - 2008 FX - Child Nutrition FX - Infant Nutrition Physiology FX - Milk FX - Milk, Human DH - Adolescent Nutrition DI - 052508 MN - SP6.021.067 MS - Nutrition of persons 10 through 19 years of age. (bvsalud.org)
  • Many of these accurate definitions can also be used in bills and treaties concerning related issues, e.g., human embryonic stem cell research, human genetic engineering, abortion, the use of abortifacients, conscience clauses, IVF and other artificial reproductive technology research and regulation, etc. (lifeissues.net)
  • What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
  • This form of cloning is unrelated to stem cell research. (eurostemcell.org)
  • American feminists and women's health activists are debating on the difficult issue of human cloning and stem cell research. (boloji.com)
  • In a Science "Policy Forum" related to the team's latest findings, David Magnus and Mildred Cho from Stanford University in Palo Alto, CA discuss international oversight and ethical issues in oocyte donation, including the need to promote realistic expectations of the outcomes of stem cell research. (scienceblog.com)
  • While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
  • Recent advances in the field of stem-cell research are giving hope to millions. (thefutureofthings.com)
  • A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
  • Human embryonic stem cell research began in the 1990s. (thetablet.org)
  • What is the Jewish perspective on stem cell research? (jewishvaluesonline.org)
  • If embryonic stem-cell research offers real possibilities for future cures then, from a Jewish point of view, it may be pursued with caution, humility, and strict supervision. (jewishvaluesonline.org)
  • Some forms of stem cell research such as the use of cells from adults or cord blood, are not controversial. (cmq.org.uk)
  • What are the potential medical benefits of stem cell research 9 what is the most likely time scale for realising them? (cmq.org.uk)
  • The possible benefits of stem cell research are unknown or at best speculative, though the prospects appear superficially attractive. (cmq.org.uk)
  • In order to better appreciate the role of stem cell research in reproductive medicine, there is a need to understand the critical biological principles of stem cell research and its potential applications to medicine. (jcpa.org)
  • While there is a great deal published on the potential medical applications of stem cell research to treat or cure diseases such as diabetes, Alzheimer's disease, Parkinson's disease, cancer, and heart disease, much less has been published on the future impact of stem cell research in reproductive medicine. (jcpa.org)
  • In 2009, in a major reversal of U.S. policy, President Obama signed an executive order pledging to "vigorously support" embryonic stem cell research. (jcpa.org)
  • As the cell begins to divide, scientists believe stem cells can be extracted and grown into tissue or organs. (boloji.com)
  • The chief one is hyper-acute rejection (HAR)-the rejection of pig organs by the human recipient. (reasons.org)
  • In fact, the research team oversaw the birth of four normal, healthy piglets with organs suitable for human transplants. (reasons.org)
  • The ICM continues to differentiate into three germ layers-ectoderm, mesoderm and endoderm, each of which follows a specific developmental destiny that takes them along an ever-specifying path at which end the daughter cells will make up the different organs of the human body. (thefutureofthings.com)
  • Another reason is the possibility of cloning organs to save lives. (freebooksummary.com)
  • In addition, as we realize cloning not only goes against religion and ethics, but it also can cause health problems.For instance, it can cause some damage to the size of the upper and lower extremities and also can affect organs such as ears or nose. (freebooksummary.com)
  • Contrary to popular belief, stem cells are present in the human body throughout life and are found in many adult organs. (jcpa.org)
  • WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
  • What deserves greater attention, however, is therapeutic cloning, a (potential) cloning application considered far more important to the biomedical and scientific communities and one far more ethically challenging. (reasons.org)
  • Those two factors make attempts to clone humans for reproductive purposes ethically troubling. (reasons.org)
  • Scientists have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury. (scienceblog.com)
  • The work also moves scientists one step closer to the goal of transplanting healthy cells into humans to replace cells damaged by diseases such as Parkinson's and diabetes. (scienceblog.com)
  • From the 31 nuclear-transfer blastocysts, the scientists derived 11 stem cell lines. (scienceblog.com)
  • A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
  • Since stem cells have the ability to turn into various other types of cells, scientists believe that they can be useful for treating and understanding diseases. (healthline.com)
  • To create iPSCs, scientists genetically reprogram the adult stem cells so they behave like embryonic stem cells. (healthline.com)
  • Because the early stem cells have the ability to become any one of the hundreds of different kinds of human cells, scientists are working on research using these cells with the aim of creating therapies to treat a variety of diseases. (jewishvaluesonline.org)
  • But some scientists are not convinced by the report, which is published today in Cell Stem Cell . (scientificamerican.com)
  • Scientists at Oregon Health & Science University and the Oregon National Primate Research Center (ONPRC) have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body. (ohsu.edu)
  • This policy is similar to that of other countries, including Israel, where scientists are funded by Government to study embryonic stem cells despite the aforementioned bioethical issue. (jcpa.org)
  • The "pros" and "cons" of human cloning research have already been dealt with at length in the literature, so they will not be reviewed here. (lifeissues.net)
  • Rather, after having published analyses of dozens of state, national, federal and international legislative attempts to ban human cloning research, I simply wish to offer seriously considered suggestions for the use of scientifically accurate language and definitions to be used in such endeavors in order to prevent loopholes which would result in much human cloning not being really banned. (lifeissues.net)
  • However, the Senate bill does allow for therapeutic cloning, known as 'nuclear transplantation', for research on therapies that could cure several serious and life-threatening diseases. (boloji.com)
  • The Society for Women's Health Research, a non-profit group, agrees that therapeutic cloning should be allowed. (boloji.com)
  • 5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
  • I knew and had great respect for the famous Protestant theologian and bioethicist Paul Ramsey, and used much of his work concerning the use of human subjects in research in my own. (lifeissues.net)
  • Stem cells are at the forefront of medical research and incite some of the most controversial ethical and religious debates worldwide. (thefutureofthings.com)
  • However, more research is needed to help understand the potential uses of amniotic fluid stem cells. (healthline.com)
  • There is a range of different views world-wide on the acceptability of research on embryonic stem cells. (cmq.org.uk)
  • The research breakthrough, led by Shoukhrat Mitalipov, Ph.D. , a senior scientist at ONPRC, follows previous success in transforming monkey skin cells into embryonic stem cells in 2007. (ohsu.edu)
  • The research team found that chemically maintaining metaphase throughout the transfer process prevented the process from stalling and allowed the cells to develop and produce stem cells. (ohsu.edu)
  • This is a remarkable accomplishment by the Mitalipov lab that will fuel the development of stem cell therapies to combat several diseases and conditions for which there are currently no treatments or cures," said Dr. Dan Dorsa, Ph.D. , OHSU Vice President for Research. (ohsu.edu)
  • Last year they used the same reproductive technology to create the world's first cloned lambs (Nature, vol 380, p 64). (newscientist.com)
  • Left outside the womb, there is not the slightest hope that it will become anything more than the embryonic life it currently represents. (jewishvaluesonline.org)
  • hESCs can be generated by SCNT using dermal fibroblasts nuclei from both a middle-aged 35-year-old male and an elderly, 75-year-old male, suggesting that age-associated changes are not necessarily an impediment to SCNT-based nuclear reprogramming of human cells. (wikipedia.org)
  • The technique used by Drs. Mitalipov, Paula Amato, M.D. , and their colleagues in OHSU's Division of Reproductive Endocrinology and Infertility, Department of Obstetrics & Gynecology, is a variation of a commonly used method called somatic cell nuclear transfer, or SCNT. (ohsu.edu)
  • More than 90% of cloning attempts fail to produce viable offspring. (wikiquote.org)
  • When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)
  • One important distinction is that while the method might be considered a technique for cloning stem cells, commonly called therapeutic cloning, the same method would not likely be successful in producing human clones otherwise known as reproductive cloning. (ohsu.edu)
  • Currently, the procedure for isolating non-reproductive cells for the nuclear transfer method involves animal enzymes and serum. (scienceblog.com)
  • It involves introduction of modified DNA into embryonic stem-cells, which will take up the DNA and hopefully express the desired genes. (freeonlineresearchpapers.com)
  • DNA microinjections is a common technique used for gene targeting as it involves manipulation and reintroduction of the genetic material into the same species. (freeonlineresearchpapers.com)
  • It involves transplanting the nucleus of one cell, containing an individual's DNA, into an egg cell that has had its genetic material removed. (ohsu.edu)
  • She is the first mammal ever created from the non-reproductive tissue of an adult animal. (newscientist.com)
  • If the same could be achieved in humans, it would mean that each of us could have clones of ourselves made from our own tissue. (newscientist.com)
  • But if, as seems likely, the Roslin team has succeeded in making an entire animal from adult tissue, it might be possible to do the same for humans. (newscientist.com)
  • Induced stem cells (iSC) are stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming. (wikipedia.org)
  • A thorough examination of the stem cells derived through this technique demonstrated their ability to convert just like normal embryonic stem cells, into several different cell types, including nerve cells, liver cells and heart cells. (ohsu.edu)
  • Doctors have been performing stem cell transplants, also known as bone marrow transplants, for decades using hematopoietic stem cells in order to treat certain types of cancer. (healthline.com)
  • While iPSCs avoid the ethical issues surrounding embryonic stem cells, the methods used to derive them sometimes induce mutations in cancer causing genes, making them unsuitable for therapeutic purposes. (the-scientist.com)
  • Their 'Human Cloning Prohibition Act of 2002' would prohibit human reproductive cloning by imposing significant criminal and civil penalties in the form of fines (at least $1 million) and up to ten years in prison. (boloji.com)
  • General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
  • For example, Zhou and Zhao report that, on the basis of a genetic analysis, their artificial PGCs were similar to mouse cells at 12.5 days of development. (scientificamerican.com)
  • A variety of nontumorigenic stem cells display the ability to generate multiple cell types. (wikipedia.org)
  • Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
  • Given this fanfare, the debate has tended to focus on reproductive cloning-the use of cloning to generate a human being-and its bizarre societal and familial side effects. (reasons.org)
  • Considered contrary to the moral law, since (it is in) opposition to the dignity both of human procreation and of the conjugal union. (wikiquote.org)
  • The Donaldson Report is, however, wrong in bracketing all stem cells together as if there were no moral issues concerning their origins. (cmq.org.uk)
  • Each of the 11 new human embryonic stem cell lines was created by transferring the nuclear genetic material from a non-reproductive cell of a patient into a donated egg, or "oocyte," whose nucleus had been removed. (scienceblog.com)
  • Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. (scienceblog.com)
  • The single cell line generated in the 2004 Science paper resulted from nuclear transfer in which the oocyte and non-reproductive ("somatic") cell came from the same healthy female. (scienceblog.com)
  • 7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)
  • For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
  • Furthermore, because these reprogrammed cells can be generated with nuclear genetic material from a patient, there is no concern of transplant rejection," explained Dr. Mitalipov. (ohsu.edu)
  • This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
  • There will always be some people who will be trying to push the boundaries for their own interests, aware or unaware that they are pushing beyond what is for the common good or in keeping with human dignity," she said. (thetablet.org)
  • The focus on human dignity, human flourishing, and justice provides a normative basis. (anselmacademic.org)
  • Note that each and every individual "loophole" discussed below that permits human cloning by default (and most bills have literally dozens of such loopholes) thus permits it for both "therapeutic" and for "reproductive" human cloning. (lifeissues.net)
  • a) Note, again, the reference to only sexual human reproduction - "the moment of conception" - i.e., fertilization. (lifeissues.net)
  • These cell lines will enable the study of human disease in cells in the laboratory. (scienceblog.com)
  • To achieve this success, Scott Noggle at the New York Stem Cell Foundation Laboratory took a unique approach to the process. (the-scientist.com)
  • In addition, specific proteins or biological substances can be added to these stem cell cultures to transform them in the laboratory into a large variety of specialized cell types, such as nerve, liver, muscle, bone, and blood cells. (jcpa.org)
  • Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
  • Aging is a physical process that doesn't normally reveal itself until after the completion of a species-specific interval of reproductive competence during which adults rear their progeny from childhood to independence (See Life History ). (agemed.org)
  • CR has been effective in all species in which it has been tried (although the jury is still out on humans). (agemed.org)
  • Previous unsuccessful attempts by several labs showed that human egg cells appear to be more fragile than eggs from other species. (ohsu.edu)
  • A breakthrough in somatic cell nuclear transfer opens the possibility of producing human embryonic stem cells with a patient's own genes. (the-scientist.com)
  • Cloning has recently become a possibility that seems much more realistic nowadays in society than a long time ago. (freebooksummary.com)
  • a) It would seem that Saunders uses the "potential" argument here quite appropriately, but it is critical that the term be understood properly in order to deflect any misunderstandings or misinterpretations - especially if the term were to be used in any U. N. treaty on human cloning. (lifeissues.net)
  • Clonaid's claim to have produced the first human clones propelled the ethical debate about human cloning to the headlines last December. (reasons.org)
  • Science, supported by the human genome project has already shown that many of the basic 'cell control' processes are common across a wide range within both animal and plant kingdoms. (cmq.org.uk)
  • Understanding human [eggs'] ability to reprogram could shed light on improved methods for reprograming," said Noggle. (the-scientist.com)
  • If the term "potential" were to be incorporated into a U. N. treaty on human cloning, it would be necessary to clarify its use as referring to an already existing human being/person. (lifeissues.net)
  • The advance here is the proof that somatic cell nuclear transfer can work [in human cells] and can fully reset the donor cell genome to a pluripotent state," said Harvard Medical School's George Daley , who was not affiliated with the study. (the-scientist.com)
  • The findings validate this controversial method, and may one day allow therapeutic stem cells to be created from a patient's own genetic material. (the-scientist.com)
  • Most common and most controversial is embryonic stem-cell mediated gene transfer. (freeonlineresearchpapers.com)
  • As happens so often in human affairs, opening the door on a controversial but somewhat defensible position (not from the Catholic Church's point of view though) bumps up against a boundary which is first deemed arbitrary and then seen as limiting true science. (thetablet.org)
  • At present, this is only possible with mice, using so-called embryonic stem cells. (newscientist.com)
  • CYP450 family members, especially Cyp2b10, whose homolog in humans is CYP2B6, led to a noticeable increase in m6A levels in HFD-induced mice livers. (bvsalud.org)
  • Diseases or conditions that might be treated through stem cell therapy include Parkinson's disease, multiple sclerosis, cardiac disease and spinal cord injuries. (ohsu.edu)
  • In therapeutic cloning on the other hand, genetic material from a body cell is inserted into an egg cell, replacing the nucleus. (boloji.com)
  • 1. Cloning is an umbrella term traditionally used to describe different processes for duplicating biological material. (who.int)
  • The technique provides the first opportunity to make hESCs that carry the same genetic material as the patients. (the-scientist.com)
  • Wang, 2003) Several methods have been devised for introduction or modification of genetic material. (freeonlineresearchpapers.com)
  • Metaphase is a stage in the cell's natural division process (meiosis) when genetic material aligns in the middle of the cell before the cell divides. (ohsu.edu)
  • Leidy Escobar 11152012 Three Reasons Why Cloning Should Not Be Allowed Cloning is the process of creating a genetic duplicate of a human being. (freebooksummary.com)
  • The potential of therapeutic cloning for treating, and perhaps curing, a variety of debilitating diseases demands that the scientific community be allowed to continue this promising work. (boloji.com)
  • Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)