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  • synchrotron radiation
  • Firstly, unsaturated polyamides nanoparticles were hardened by continuous synchrotron radiation and then, the induced changes in its chemical structure were studied by Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) spectroscopy. (sciencepubco.com)
  • It was shown that applying synchrotron radiation for hardening not only leads to reduction of hardening time but also creates cross link in polymer by breaking Carbon-Carbon double bond, without any considerable change in its chemical structure. (sciencepubco.com)
  • In addition, an unsaturated polyamide nanoparticle as anti-cancer polymeric nanomedicines is hardened by synchrotron radiation. (sciencepubco.com)
  • A Scanning Electron Microscope (SEM) image of interaction between heavy metals toxicity and diseases in disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent nanomolecules adjustment in cancer metastases using metalloenzymes and under synchrotron radiation [33-. (ommegaonline.org)
  • pathways
  • Genetic interactions among various cancer-related pathways often provide redundant input from parallel and/or cooperative pathways that drives and maintains survival environments for cancer cells, leading to low efficacy of single-target agents. (mdpi.com)
  • Therefore, targeting DNA DSB repair pathways can be a potential therapeutic strategy to enhance the antitumor effect of radiation. (biomedcentral.com)
  • The researchers analysed over 8,000 molecular pathways involved in genetic changes and mined data from multiple human cell experiments in a space station, during space flight and facilities producing zero gravity-like conditions on earth. (medicaldialogues.in)
  • sensitivity
  • This invention provides a method of increasing sensitivity of cells to the cyctotoxic effects of ionizing radiation which includes incubating the cells with a spindle poison in a suitable carrier at a concentration effective to inhibit the cells from progressing through G2 or M phases of the cell cycle. (google.es)
  • A total of 35 SNVs showed possible association with sensitivity to at least one of the nine drugs. (aacrjournals.org)
  • ultraviolet
  • When the DNA in a cell becomes damaged by agents such as toxic chemicals, radiation, or ultraviolet (UV) rays from sunlight, this protein plays a critical role in determining whether the DNA will be repaired or the damaged cell will self-destruct (undergo apoptosis). (nih.gov)
  • development
  • In fact, a major cause of failure of anticancer drug development is lack of efficacy. (mdpi.com)
  • Targeting autophagy in cancer will provide new opportunities for drug development, because more potent and specific inhibitors of autophagy are needed. (aacrjournals.org)
  • Given that these are the doses of most concern to genetic toxicology, the development of new, more sensitive and efficient approaches for evaluating the germ line effects of chemical mutagens is warranted. (aacrjournals.org)
  • The cause of isolated missing teeth remains unclear, but the condition is believed to be associated with genetic or environmental factors during dental development . (wikipedia.org)
  • cellular
  • However, current research suggests that abnormalities of DNA (deoxyribonucleic acid), which is the carrier of the body's genetic code, are the underlying basis of cellular malignant transformation. (rarediseases.org)
  • liver
  • Through a new type of analysis (systems biology), we have found the genetic signature for leukemia and liver cancer," Sangram Bagh, Ramanujan Fellow, Associate Professor, Biophysics and Structural Genomics Division, SINP, told IANS. (medicaldialogues.in)
  • Our study is the first one to report genetic signatures for liver and leukemia in micro-gravity," said Bagh. (medicaldialogues.in)
  • approaches
  • Borghaei has served the role of principal and supporting investigator in numerous clinical trials, which are medical studies that aim to evaluate the safety and effectiveness of new drugs and approaches to treatment. (asbestos.com)
  • chemical
  • The suitability of a single-molecule PCR-based approach for monitoring mutation induction at the mouse expanded simple tandem repeat (ESTR) locus Ms6-hm by chemical mutagens and anticancer drugs has been validated. (aacrjournals.org)
  • program
  • Plus: help for low-fat/low-cholesterol living, engineering an anticancer tobacco, an exercise program for asthmatics, preventing exercise injuries, tips to prevent bullying, the connection between allergies and bed-wetting, and new information about gum disease. (motherearthnews.com)
  • certain
  • Various benign (non-cancerous) forms of AN have been identified in which the disorder may be inherited as a primary condition or associated with various underlying syndromes, an excess accumulation of body fat (obesity), or the use of certain medications (i.e., drug-induced AN). (rarediseases.org)