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  • metabolic
  • Therefore, metabolic pathways must be synchronized with energy needs of a reproducing female mosquito. (prolekare.cz)
  • Identification and characterisation of metabolic pathways (in particular of carbon and iron uptake) that are required for intracellular proliferation of R. equi. (ucd.ie)
  • However, the original metabolic pathway devised to convert acetate to ethanol uses NADH-specific acetylating acetaldehyde dehydrogenase and alcohol dehydrogenase and quickly becomes constrained by limited NADH availability, even when glycerol formation is abolished. (asm.org)
  • The l -valine production strain of Escherichia coli was constructed by rational metabolic engineering and stepwise improvement based on transcriptome analysis and gene knockout simulation of the in silico genome-scale metabolic network. (pnas.org)
  • Synthetic microbial coculture to express heterologous biosynthetic pathway for de novo production of medicinal ingredients is an emerging strategy for metabolic engineering and synthetic biology. (bioportfolio.com)
  • Metabolic Pathway Engineering for High-level Production of 5-Hydroxytryptophan in Escherichia coli. (bioportfolio.com)
  • To produce bio-chemicals with engineered microorganisms, metabolic pathways have been edited using several common strategies, including gene disruption, gene overexpression, and gene attenuation. (bioportfolio.com)
  • Although M. aeruginosavorus depends on prey for replication, the genome encodes for most of the major metabolic pathways. (kenyon.edu)
  • The TOR1 and SNF1 networks are likely to regulate for example amino acid, energy and lipid metabolic pathways in concert [ 7 ], integrating signals of nutritional and metabolic state. (biomedcentral.com)
  • To understand Synechococcus 2973's fast-growth phenotype and its metabolic features advantageous to photo-biorefineries, 13 C isotopically nonstationary metabolic flux analysis (INST-MFA), biomass compositional analysis, gene knockouts, and metabolite profiling were performed on both strains under various growth conditions. (biomedcentral.com)
  • Metabolic flux analysis (MFA) can provide a quantitative description of the metabolic network, link genome profiling to phenome analysis, and reveal pathway regulations through comparative studies. (biomedcentral.com)
  • proteins
  • Trypomastigotes, living extracellularly in the bloodstream of mammals, express a plethora of surface proteins and signaling genes involved in invasion and evasion of immune response. (peerj.com)
  • Although it has been shown that genes located in this island are essential for virulence, the function of the proteins they encode remains largely unknown. (ucd.ie)
  • An unexpectedly large number of genes are predicted to encode proteins involved in the production, degradation, and efflux of toxins and metabolites. (asm.org)
  • 4 Numerous genes are encoded which have an important role in predator-prey interaction, for example, hemolysin-related proteins. (kenyon.edu)
  • Nine genomic islands encode multiple genes important for predator-prey interaction (hemolysin-related proteins) (4). (kenyon.edu)
  • The gene categories with the most genes conserved in all strains were those involved in biosynthesis or degradation of structural compounds like proteins, lipids, and DNA. (asm.org)
  • In fact, as a result of an interspecies study it was conjectured that more than 70% of the genes that are obtained by horizontal transfer encode proteins of unknown function ( 13 ). (asm.org)
  • We also find that expression of many genes of secreted proteins and secondary metabolism, as well as various lineage specific, mostly unknown genes are positively correlated with SPPR. (biomedcentral.com)
  • The transcription factor BTB and CNC homology 1 (Bach1) is widely expressed in most mammalian tissues and functions primarily as a transcriptional suppressor by heterodimerizing with small Maf proteins and binding to Maf recognition elements in the promoters of targeted genes. (hindawi.com)
  • carbohydrate
  • During the pre-blood meal phase, the JH receptor Methoprene-tolerant (Met) controls carbohydrate metabolism (CM) pathways and its RNA interference (RNAi) silencing caused up-regulation of CM enzymes at the transcript and protein levels activating glycolytic flux and depletion of storage and circulating sugars. (prolekare.cz)
  • genomic
  • To assess if this versatility is linked to a variable gene pool, microarrays containing a subset of small genomic fragments of L. plantarum strain WCFS1 were used to perform stringent genotyping of 20 strains of L. plantarum from various sources. (asm.org)
  • Genomes
  • Genes shared among the three roseobacters and also common in nine draft Roseobacter genomes include those for carbon monoxide oxidation, dimethylsulfoniopropionate demethylation, and aromatic compound degradation. (asm.org)
  • Fungal genomes are a mosaic of chromosomal regions (or whole supernumary chromosomes [ 10 , 11 ]), where gene content and order is mostly conserved between closely related species (syntenic blocks) and regions where it is not conserved (non-syntenic blocks). (biomedcentral.com)
  • Nrf2
  • In this review, we focus our attention on the deleterious properties of Nrf2, and of its target gene HO-1, in relation to cancer cell growth and chemoresistance. (hindawi.com)
  • Genes regulated by Nrf2 in mice and humans. (hindawi.com)
  • The human Nrf2 was first described, cloned, and characterised by Moi and coworkers in 1994 [ 13 ] and its cloned gene is encoded within a 2.2 kB transcript, predicting a protein of 589 amino acids with a molecular mass of 66.1 kDa [ 13 ]. (hindawi.com)
  • tolerance
  • These results demonstrate a strong relationship between PPP genes and furfural tolerance and provide additional putative target genes involved in furfural tolerance. (springer.com)
  • amino
  • Eight novel XI genes were obtained from a cDNA library, prepared from the protists of the R. speratus hindgut, by PCR amplification using degenerated primers based on highly conserved regions of amino acid sequences of different XIs. (biomedcentral.com)
  • organisms
  • For a number of genes located in plasticity zones of other organisms, a function in niche adaptation has been shown or proposed, but in many cases, their function is unknown. (asm.org)
  • respectively
  • Among the down-regulated genes, the lrp and ygaZH genes, which encode a global regulator Lrp and l -valine exporter, respectively, were overexpressed. (pnas.org)
  • Amplification of the lrp , ygaZH , and lrp-ygaZH genes led to the enhanced production of l -valine by 21.6%, 47.1%, and 113%, respectively. (pnas.org)
  • chromosomal
  • In these studies, information about relative gene position and chromosomal organization is lost but may be obtained by PCR techniques ( 37 ). (asm.org)
  • important
  • It has become clear that horizontal gene transfer is an important mechanism for generating genotypic and phenotypic diversity in bacteria. (asm.org)
  • hence
  • In particular, it induces glucose repressed genes by phosphorylating and hence inactivating a repressing transcription factor, MIG1 , and activating other inducing transcription factors such as ADR1 and CAT8 . (biomedcentral.com)
  • Identification
  • Isolation of this XI gene and identification of the point mutation described in this study might contribute to improving the productivity of industrial bioethanol. (biomedcentral.com)