• A]s bacterial infections of eukaryotic cells involve two interacting organisms with profoundly different transcriptomes, RNA-seq studies are commonly restricted to either the pathogen or host after their physical separation," the authors wrote. (genomeweb.com)
  • Now, Stanford scientists have found a new type of cellulose in bacteria with properties that could make it an improvement over traditional cellulose for fuels and other materials, or for better understanding and treating bacterial infections. (stanford.edu)
  • 3] Viral infections have also been implicated. (medscape.com)
  • Diagnosis involves blood tests to measure growth hormone levels. (wikipedia.org)
  • Some patients develop active primary TB, resulting in disseminated miliary infection or TB meningitis, but these disease manifestations cause death of the host without transmission of Mtb. (ersjournals.com)
  • A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications. (mdpi.com)
  • Using genetic approaches we identified several genes that may be involve in the ability of a vector to transmit disease. (usda.gov)
  • It had been missed by decades of previous research because traditional lab techniques involve harsh chemicals that stripped the modification. (stanford.edu)
  • Subsequent analyses of the small RNA suggest it regulates S. enterica genes involved in cell invasion and survival. (genomeweb.com)
  • The mechanisms whereby Mtb disseminates from the initial Ghon focus are not well understood, but studies in the zebrafish model of M. marinum infection suggest that Mtb is transported within infected monocytes [ 4 ]. (ersjournals.com)
  • As the disease progresses and converts into leukemia, further gene mutation occurs, and a proliferation of leukemic cells overwhelms the healthy marrow. (medscape.com)
  • Mtb can only transmit when there is reactivation of infection in the lung, which usually occurs at the apices or in the apical segments of the lower lobes. (ersjournals.com)
  • MDS may involve one, two, or all three myeloid hematopoiesis cell lineages-erythrocytic, granulocytic, megakaryocytic-depending on the subtype and stage of the disease. (medscape.com)
  • Our findings with PinT and other intracellularly induced [small RNAs] illustrate how small perturbations in the infection process, such as dysregulation of a few Salmonella mRNAs, can propagate through the entire host system, potentially leading to different disease outcomes in the context of a whole organism," the researchers concluded. (genomeweb.com)
  • thus, it may be possible for transmission to occur via asymptomatic persons or persons with subclinical disease, who may be unaware that they have been exposed to the infection. (medscape.com)
  • Our study provides a paradigm for a sensitive RNA-based analysis of intracellular bacterial pathogens and their hosts without physical separation, as well as a new discovery route for hidden functions of pathogen genes," senior author Jörg Vogel, a molecular infection biology and infectious diseases researcher at the University of Würzburg, and colleagues wrote. (genomeweb.com)
  • A more complete list of causes includes: mutations of specific genes (e.g. (wikipedia.org)
  • Tests of nasopharyngeal specimens for specific pathogens are helpful when targeted therapy depends on the results (eg, group A streptococcal infection, gonococcus, pertussis). (medscape.com)
  • In the process, they narrowed in on a small RNA called PinT that is activated by Salmonella upon host cell infection. (genomeweb.com)
  • In addition, two putative cell surface signal transduction receptors, CsLAR and CsFZ2, involved in cell differentiation, were also identified. (usda.gov)
  • All 3 cell lineages in myeloid hematopoiesis can be involved, including erythrocytic, granulocytic, and megakaryocytic cell lines. (medscape.com)
  • Urinary tract infections (UTIs) are one of the most important causes of morbidity and health care spending affecting persons of all ages. (mdpi.com)
  • Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
  • Through a series of follow-up experiments, the group demonstrated that the small RNA acts not only as a co-activator of Salmonella genes important to invasion, infection, and intracellular replication, but also as a regulator of coding and non-coding transcripts produced by infected host cells. (genomeweb.com)
  • Genes that may be involved include GH1, GHRHR, or BTK. (wikipedia.org)
  • Using subtractive libraries and reverse Northern blot analysis, we have identified 50+ cDNAs that appear to be more highly expressed in midge midguts or heads at various times during an orbivirus (EHDV) infection. (usda.gov)
  • treatment of infections. (lu.se)
  • Can Food Safety Practices and Knowledge of Raw Fish Promote Perception of Infection Risk and Safe Consumption Behavior Intentions Related to the Zoonotic Parasite Anisakis? (researchgate.net)
  • CDC received a case report of acquired immunodeficiency syndrome (AIDS) in a young woman for whom an epidemiologic investigation had not established a source for her human immunodeficiency virus (HIV) infection (i.e., documented behavioral or other risk factors, including intravenous (IV)-drug use, sex with an HIV-infected person, or receipt of a blood transfusion or blood components). (cdc.gov)
  • Multiple interviews of the patient and her family and friends by health department staff and review of her medical and previous dental records did not identify factors that may have potentially placed her at risk for HIV infection. (cdc.gov)
  • Details of the patient's history aid in differentiating a common cold from conditions that require targeted therapy, such as group A streptococcal pharyngitis , bacterial sinusitis, and lower respiratory tract infections. (medscape.com)
  • Although RNA sequencing is increasingly being used to explore host and pathogen features involved in infection, the team explained, most studies have focused on protein-coding transcripts, assessing bacterial RNA sequences and host RNAs separately. (genomeweb.com)
  • Fish are often speckled with 'black spots' caused by metacercarial trematode infection, inducing a host response. (researchgate.net)
  • The aim of this work was to investigate the addiction systems carried by the replicons involved in the emergence and spread of ESBLs in relation to ESBL and replicon types. (who.int)
  • Infection is spread by the aerosol route and Mycobacterium tuberculosis must drive lung destruction to be transmitted to new hosts. (ersjournals.com)
  • Based on dual RNA-seq experiments done at five time points during the first day of infection, they uncovered hundreds of new and known small RNAs from Salmonella . (genomeweb.com)
  • Produced by plants, algae and some bacteria, cellulose is an abundant molecule involved in the production of hundreds of products, from paper to fabrics to renewable building materials. (stanford.edu)
  • The heterogeneity of MDS reflects the fact that its course involves a series of cytogenetic events. (medscape.com)
  • One of these, PinT, showed the highest levels of activation after infection, the team reported. (genomeweb.com)
  • The patient reported no previous test for HIV infection. (cdc.gov)
  • After isolating cells four hours and 24 hours post-infection, the team used the Illumina HiSeq 2000 instrument to generate tens of millions of reads from total RNA present in the samples. (genomeweb.com)