Genes in filamentous fungus. Medical search. Frequent questions

An Osaka Metropolitan University research team analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in Aspergillus aculeatus, a filamentous fungus that produces enzymes with an excellent ability to degrade plant biomass. (asiaresearchnews.com)
Delving into this field, a research team led by Associate Professor Shuji Tani, from the Graduate School of Agriculture at Osaka Metropolitan University, analyzed the regulatory mechanisms of carbohydrate-hydrolyzing enzyme production in the filamentous fungus Aspergillus aculeatus , which produces enzymes that have an excellent ability to degrade plant biomass. (asiaresearchnews.com)
Professor Tani explained, "We constructed and screened a library containing approximately 9,000 gene-disrupted strains of Aspergillus aculeatus, and identified Uge5 as a novel regulatory factor that regulates the production of carbohydrate-hydrolyzing enzymes. (asiaresearchnews.com)
The genome of Aspergillus oryzae , a fungus important for the production of traditional fermented foods and beverages in Japan, has been sequenced. (nature.com)
Here we show that the 37-megabase (Mb) genome of A. oryzae contains 12,074 genes and is expanded by 7-9 Mb in comparison with the genomes of Aspergillus nidulans 5 and Aspergillus fumigatus 6 . (nature.com)
To develop filamentous fungi from the genera Aspergillus and Penicillium as safe and sustainable biofactories to produce compounds and proteins (including antifungal proteins) of agricultural and food interest (participation in the H2020 European project Pre-HLB). (csic.es)
The identification of Aspergillus flavus and A. parasiticus isolates was confirmed by Regional Center of the Fungi and their Applications, Al-Azhar University, Cairo, Egypt. (hindawi.com)
The nudF gene of the filamentous fungus Aspergillus nidulans acts in the cytoplasmic dynein /dynactin pathway and is required for distribution of nuclei. (xenbase.org)
CreA/CRE1 binds to the promoters of the respective target genes via the consensus motif 5'-SYGGRG-3', whose function in vivo has been shown both in Aspergillus nidulans and Trichoderma reesei [ 9 - 12 ]. (biomedcentral.com)
Aspergillus is a genus of filamentous fungi with huge geographic and ecological distributions. (computablegenomix.com)
cAMP signaling factors regulate carbon catabolite repression of hemicellulase genes in Aspergillus nidulans . (megazyme.com)
In this report, we examined how deletion of pkaA and ganB , which encode cAMP signaling factors, and creA , which encodes a well-characterized repressor of CCR, affects CCR of hemicellulase genes in the filamentous fungus Aspergillus nidulans . (megazyme.com)
Expression out-of a bacterial aspartase gene in the Aspergillus nidulans: a simple yet effective system for choosing multicopy transformants. (bulle-dair-coiffure.fr)
1985). Gene amplification in the Aspergillus nidulans by conversion with vectors which has had the amdS gene. (bulle-dair-coiffure.fr)

The transcriptional profile of 11 fungal genes related to pathogenicity and virulence were evaluated by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). (frontiersin.org)
When haploid fungal spores germinate, their nuclei divide mitotically to produce hyphae (the structural unit of a fungus in its vegetative phase or mycelium). (tripod.com)
We are studying the so-called antifungal proteins (AFPs) of fungal origin, of which the AfpA from the fungus Penicillium expansum is a promising candidate whose use in food conservation, plant protection and clinic has been patented and is being pursued. (csic.es)
In this we have gathered complementing methodological competences so we now have a platform for exploiting technologies with filamentous fungi such as: Fungal transformation & gene constructions, DNA reporter technology (GFP, DsRed etc.), advanced fluorescent microscopy, gene knock outs and complementation, arrays and quantitative PCR, fungal characterization and diagnostic molecular tools as well as methods in evolutionary genetics. (slu.se)
We are also building up expertise in genomics and transcriptomics for studying community structures and their function, and gene expression in fungal host interactions. (slu.se)
Specifically, we exploit CRISPR-Cas9-based genome editing to identify a new gene in T. atroroseus responsible for production of polyketide-nonribosomal peptide hybrid products, hence, linking fungal secondary metabolites to their genetic origin in a species where no genetic engineering has previously been performed. (unl.edu)
utilize the potential of filamentous fungi as biocontrol agents, antagonists of other fungal phytopathogens, bioherbicides and as bioinsecticides (Kapoor, 1995). (taylorfrancis.com)
The present study aimed to investigate the capability of the filamentous fungus Penicillium parvum 4-14 to enzymatically saccharify CBAX and reveal the fungal carbohydrate-active enzyme (CAZyme) repertoire by genome sequencing and secretome analysis. (biomedcentral.com)
and incubating the growth media in each container for a period of time sufficient for the fungus to digest the nutritive substrate and produce a mycelium biopolymer consisting entirely of fungal mycelium in each container. (justia.com)
Biofilms have primarily been studied in single-celled organisms, but there is a growing body of work on filamentous fungal biofilms. (msu.edu)
The fungal cell cyle is considered with respect to the mechanism of sequential gene expression in Candida albicans, since little is known about the cell cycle in pathogenic molds. (cdc.gov)
It derived from the characteristic filamentous, branching morphology of the organisms resembling fungal hyphae. (medscape.com)

In this work, we implemented FUN-LOV, an optogenetic switch based on the photon-regulated interaction of WC-1 and VVD, two LOV (light-oxygen-voltage) blue-light photoreceptors from the fungus Neurospora crassa When tested in yeast, FUN-LOV yields light-controlled gene expression with exquisite temporal resolution and a broad dynamic range of over 1,300-fold, as measured by a luciferase reporter. (nih.gov)
The genome sequence of the filamentous fungus Neurospora crassa. (genscript.com)
The product of the nudE gene isolated in the screen, NUDE, is a homologue of the nuclear distribution protein RO11 of Neurospora crassa. (xenbase.org)
The model filamentous fungus Neurospora crassa is capable of utilizing sulfur found in a variety of sources from amino acids to sulfate. (escholarship.org)
Sulfur is an important nutrient source found in proteins, lipids, and electron carriers that are required for the survival of filamentous fungi such as Neurospora crassa. (escholarship.org)

Filamentous fungi (molds) are microorganisms with a long history of use in the fermentation of sake, soy sauce, cheese, and many other products. (asiaresearchnews.com)
From there, many plant defensins have been reported and studies on this class of peptides encompass its activity toward microorganisms and molecular features of the mechanism of action against bacteria and fungi. (frontiersin.org)
Objective 1: Identify and characterize microorganisms and microbial genes that can reduce trichothecene contamination of grain-based food and feed. (usda.gov)
Among microorganisms, fungi and actinomycetes have been successfully developed for industrial applications. (taylorfrancis.com)
Many filamentous fungi have developed a predominantly saprobic lifestyle, in which successful competition with other microorganisms for the limited resources present in the environment is the key for survival. (biomedcentral.com)
Filamentous fungi are ubiquitous microorganisms in indoor and outdoor environments and acquire nutrients from a wide variety of substrates such as decaying plant matter or water-damaged building materials [1] . (cdc.gov)
Microorganisms capable of catabolizing lignin-derived ar- carbohydrate and protein components of the organic matter omatics are essentially fungi and bacteria (Bugg et al. (lu.se)

We will isolate and characterize major contributors (yeasts, filamentous fungi, and bacteria) to the microbial community associated with wheat cultivation. (usda.gov)
The members of the group are experts in food microbiology , microbial biotechnology of filamentous fungi and yeasts , and in the characterization of bioactive peptides and proteins . (csic.es)
Other primer sets have been used for other genes, but those described below are the most consistently available in databases for the identification of yeasts and molds that are most likely to be identified in a clinical microbiology laboratory. (cdc.gov)
Although the ITS primers are universal for fungi, the D1D2 region of the large ribosomal subunit has better discrimination for yeasts, with primers NL-1 and NL-4. (cdc.gov)

Previously, a loss-of-function mutation in the gene encoding the copper-sensing and copper-regulated transcription factor GRISEA of the filamentous fungus Podospora anserina was reported to lead to cellular copper depletion and a pleiotropic phenotype with hypopigmentation of the mycelium and the ascospores, affected fertility and increased lifespan by approximately 60% when compared to the wild type. (uni-frankfurt.de)
Nonintegrative conversion on filamentous fungus Podosporu anserina: stabilizing out of a linear vector by chromosomal finishes of Tetrahymena thermophila. (bulle-dair-coiffure.fr)

Bacteria, protoctista, fungi and plants have well studied compatibility systems. (tripod.com)
Fungus also are higher level bacteria to produce pharmaceuticals and other high-value affairs. (kedroom.ru)

Primers and copper responsive promoter design and data of real-time RT-PCR assay in filamentous fungus Trichoderma reesei. (redasoft.com)
This knowledge article accommodates knowledge associated to the analysis article entitled "Copper-mediated on-off management of gene expression in filamentous fungus Trichoderma reesei" (Wang et al. (redasoft.com)
Here, we deciphered the CRE1 regulatory range in the model cellulose and hemicellulose-degrading fungus Trichoderma reesei (anamorph of Hypocrea jecorina ) by profiling transcription in a wild-type and a delta- cre1 mutant strain on glucose at constant growth rates known to repress and de-repress CCR-affected genes. (biomedcentral.com)
Establishment of a CRISPR/Cas9-Mediated Efficient Knockout System of Trichoderma hamatum T21 and Pigment Synthesis PKS Gene Knockout. (qxmd.com)
Trichoderma hamatum is a filamentous fungus that serves as a biological control agent for multiple phytopathogens and as an important resource promising for fungicides. (qxmd.com)
The situations were caused by different DNA repair mechanisms, nonhomologous end joining (NHEJ), and homologous recombination (HR). Overall, we have successfully constructed an efficient and convenient CRISPR/Cas9 system in T. hamatum for the first time, which has important scientific significance and application value for studies on functional genomics of Trichoderma and other filamentous fungi. (qxmd.com)

This analysis verified but also corrected conclusions from earlier data obtained by single gene analysis, identified new candidates of factors as part of the cellular copper homeostasis system including target genes of transcription factor GRISEA, and provides a rich reference source of quantitative data for further in detail investigations. (uni-frankfurt.de)
This document describes some of the target genes and primers that can be used for DNA sequence-based identification of fungi and the PCR conditions with which to use those primers. (cdc.gov)

The studies on the compatibility systems in Basidiomycetes 19 include those on the smut fungus Ustilago maydis 23-26 , U.hordei 8 and the edible members (mushrooms) Schizophyllum commune 7 and Coprinus cinereus 27 . (tripod.com)
Regine Kahmann from the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, has long studied a corn pathogen, the fungus Ustilago maydis . (nature.com)

We developed a screen to pinpoint the antifungal mechanisms of KP4-like proteins by using a cataloged collection of over 4000 Saccharomyces cerevisiae mutants transformed with a KP4-like gene of interest. (boisestate.edu)
Osaka Metropolitan University researchers have revealed the regulatory mechanisms of enzyme production in a filamentous fungus that allows for efficient degradation of plant biomass, an alternative energy resource to petroleum. (asiaresearchnews.com)
Enterobacterales and fungi), their resistance mechanisms, and the improvement of diagnostic methods. (cdc.gov)
Sub-objective 1.2: Identify trichothecene resistance mechanisms in a diversity of trichothecene-producing fungi. (usda.gov)
As a parallel approach to trichothecene detoxification we will identify resistance mechanisms from diverse fungi that produce trichothecenes and have naturally developed strategies to cope with exposure to these toxins. (usda.gov)
Today, a plethora of genes have been shown to be under control of CreA or CRE1 (reviewed in [ 7 ]) but the mechanisms triggering regulation by CreA/CRE1 are less well understood. (biomedcentral.com)
Overall, the present study demonstrates the importance of systems biology approaches also in cases were mutations in single genes are analyzed to explain the underlying mechanisms controlling complex biological processes like aging and development. (uni-frankfurt.de)
While much is known about how F. graminearum initiates disease into its host plants, there are still knowledge gaps related to plant signals sensed by the fungus, and mechanisms that increase success in infection. (msu.edu)
Carbon catabolite repression (CCR) enables preferential utilization of easily metabolizable carbon sources, implying the presence of mechanisms to ensure discriminatory gene repression depending on the ambient carbon sources. (megazyme.com)

This project is ongoing with the investigation of the lethal characteristics of several KP4-like proteins from various filamentous fungi. (boisestate.edu)
The 37-Mb genome was predicted to contain a total of 12,074 genes encoding proteins with a length greater than 100 amino acid residues (see Methods). (nature.com)
3) The development of fungi as sustainable and efficient biofactories to produce compounds and proteins of agricultural and food interest. (csic.es)
Among CRE1 repressed transcripts, genes encoding unknown proteins and transport proteins were overrepresented. (biomedcentral.com)

Talbot studies the fungus Magnaporthe oryzae , which leads to the rice blast that brings on periodic epidemics and devastating crop loss in China, Korea, Japan and the United States. (nature.com)

24. VanEtten, H.. D.Funell-Baerg, C. Wasmann, K. McCluskey (1994).Venue away from pathogenicity genes on dispensable chromosomes in Nectna haematococca MMVI. (kedroom.ru)

However, the emergence of several CRISPR-Cas9-based genome editing systems adapted for several genera of filamentous fungi have now opened the doors for future efforts in discovery of novel natural products and elucidation and engineering of their biosynthetic pathways in fungi where no genetic tools are in place. (unl.edu)

These synthetic switches have become a powerful tool for gene regulation, allowing modulation of customized phenotypes, overcoming the obstacles of chemical inducers, and replacing their use by an inexpensive resource: light. (nih.gov)
Here, we report a novel optogenetic switch (FUN-LOV) based on the LOV domain interaction of two blue-light photoreceptors (WC-1 and VVD) from the fungus N. crassa In yeast cells, FUN-LOV allowed tight regulation of gene expression, with low background in darkness and a highly dynamic and potent control by light. (nih.gov)
The sessions on growth and reproduction was on the different aspects of development, morphogenesis and regulation in several fungi, with emphasis on genetic regulators and biochemical signals. (bspp.org.uk)
Our study provides the first global insight into the molecular physiological response of a multicellular fungus to carbon catabolite regulation and identifies several not yet known targets in a growth-controlled environment. (biomedcentral.com)
Additionally, CYS-3 directly activated the expression of a number of uncharacterized transporter genes, suggesting that regulation of sulfur import is an important aspect of regulation by CYS-3. (escholarship.org)
Furthermore, we analyzed a subset of genes regulated by SIN3 187 that suggest a mechanism in which SIN3 187 might exhibit hard regulation as well as soft regulation. (bvsalud.org)

The session on genome evolution discussed the increase in available genome databases and how this information has identified genes involved in morphological and physiological processes. (bspp.org.uk)

The team found that UDP-glucose 4-epimerase (Uge5), an enzyme known for its involvement in galactose metabolism, also regulates the expression of degrading enzyme genes in A. aculeatus. (asiaresearchnews.com)
However, the team discovered that Uge5 also regulates the expression of degrading enzyme genes in A. aculeatus . (asiaresearchnews.com)
The heterokaryon compatibility system (het loci) regulates the heterokaryon formation in filamentous fungi. (tripod.com)
All these findings suggest that the IR of cellulase genes regulates their own gene expression by coupling with the NMD pathway, which might involve the TOR pathway. (researchsquare.com)
The SIN3 histone modifying complex regulates the chromatin environment leading to changes in gene expression. (bvsalud.org)

Subsequently, many of these genomes have been carefully studied to identify new genes and biosynthetic pathways. (wikipedia.org)
During sulfur starvation, genes involved in nitrogen metabolism, such as amino acid and nucleic acid metabolic pathways, along with genes encoding proteases and nucleases that are necessary for scavenging nitrogen, were activated. (escholarship.org)
Yeast-form-specific genes identified in Histoplasma capsulatum function in calcium/calmodulin signaling pathways and sulphur metabolism. (cdc.gov)

These haploid hyphae in filamentous fungi may be in a dikaryotic stage (n+n) which is different from haploid (n) or diploid (2n) state. (tripod.com)
C albicans is dimorphic, having both yeast and filamentous forms (eg, hyphae, pseudohyphae, germ tubes), and is assumed to have increased virulence in immunocompromised patients because of the filamentous forms. (medscape.com)

The production of natural products is regulated by the biosynthetic gene clusters (BGCs) encoded in the microorganism. (wikipedia.org)
BIG-FAM is a biosynthetic gene cluster family database. (wikipedia.org)
DoBISCUIT is a database of secondary metabolite biosynthetic gene clusters. (wikipedia.org)
MIBiG (Minimum Information about a Biosynthetic Gene cluster specification) provides a standard for annotations and metadata on biosynthetic gene clusters and their molecular products. (wikipedia.org)
PCR was used with four sets of primer pairs for nor-1, omt-1, ver-1 , and aflR genes, enclosed in the aflatoxin biosynthetic pathway. (hindawi.com)

This study obtained a genome assembly of T. hamatum T21, with a 41.4 Mb genome sequence comprising 8170 genes. (qxmd.com)

He focussed on families of genes encoding carbohydrate active enzymes (CAZys) and oxido-reductases (OR) lying in the genomes of 30 species, with emphasis on findings in white and brown rot fungi across the taxa. (bspp.org.uk)
Thus far, mining of 9 genomes reveals that white rot fungi are CAZyand OR-enriched relative to brown rot species. (bspp.org.uk)
Several species of filamentous fungi are known to produce pharmaceuticals, antibiotics, metabolites, phytohormones, and other industrially important products. (taylorfrancis.com)
Species inside this genus are clinically, agriculturally and biotechnologically related, resulting in growing curiosity in elucidating gene expression dynamics of key metabolic and physiological processes. (computablegenomix.com)
However, the lack of adequate knockout technologies has hindered gene function and biocontrol mechanism research of this species. (qxmd.com)
Filamentous forms may contribute to colonization and infection, although species that do not form filaments, such as Candida glabrata, colonize and cause invasive disease in VLBW infants. (medscape.com)

The design and generation of new transformation strategies to manipulate specific gene expression and function in diverse filamentous fungi, including those having a biotechnical significance has been achieved by better understanding of fundamental genetic processes. (taylorfrancis.com)
With developments in genetic engineering and molecular biology, filamentous fungi have also achieved increased attention as hosts for recombinant DNA. (taylorfrancis.com)
Autosomal Recessive Genetic disorders determined by a single gene (Mendelian disorders) are easiest to analyze and the most well understood. (msdmanuals.com)

Importantly, FUN-LOV's ability to accurately manipulate gene expression, with a high temporal dynamic range, can be exploited in the analysis of diverse biological processes in various organisms. (nih.gov)
Plant defensins also have been tested as biotechnological tools to improve crop production through fungi resistance generation in organisms genetically modified (OGM). (frontiersin.org)
tools (the FungalBraid platform) that are exchangeable among fungi and even with other organisms (i.e., plants) to improve the biotechnological use of filamentous fungi (Projects FunFact and SUSPHIRE). (csic.es)

The blocks of A. oryzae -specific sequence are enriched for genes involved in metabolism, particularly those for the synthesis of secondary metabolites. (nature.com)

We found 39 candidate genes potentially related to the cause of the lethal phenotype of the KP4-like protein from Basidiobolus meristosporus produced by our screening process. (boisestate.edu)
Southern nalyses at medium and high stringency indicated that G. cingulata possesses ne gene for the secreted aspartic proteinase, and Northern blots indicated that gene expression was induced by exogenous protein and repressed by ammonium salts. (microbiologyresearch.org)
NUDF protein, the product of the nudF gene, displays 42% sequence identity with the human protein LIS1 required for neuronal migration. (xenbase.org)
In lower multicellular fungi, the C2H2 zinc finger CreA/CRE1 protein has been shown to act as the transcriptional repressor in this process. (biomedcentral.com)
The protein blends E_CBAX1, E_CBAX2, and E_CBR were produced by the fungus grown on CBAX1, CBAX2, or CBR, respectively. (biomedcentral.com)
In Drosophila melanogaster, the Sin3A gene is alternatively spliced to produce different protein isoforms, two of which include SIN3 220 and SIN3 187. (bvsalud.org)
A further chapter discusses how surface membrane G-protein receptors in C. albicans and other fungi transmit external stimuli through 2 major protein kinase cascades. (cdc.gov)

The indicated mutants (all are conditional, temperature sensitive) were transformed with either the empty vector pAid or pAid clones bearing nudE and nudF6 genes (plasmids recovered in the multicopy suppressor screen) and grown at 32°C. Transformants were gridded on YAG plates with or without KCl and incubated at 43°C or 32°C for 2 d. (xenbase.org)
Replicative conversion of the filamentous fungus Ashbyu gossypii with plasmids containing Saccharomyces cerevisiae ARS issues. (bulle-dair-coiffure.fr)

We will identify and characterize trichothecene detoxification genes from microbes capable of surviving mycotoxin exposure. (usda.gov)
Some plant labs work on new ways to characterize how plants, fungi and other microbes interact. (nature.com)

IMPORTANCE Optogenetic switches are molecular devices which allow the control of different cellular processes by light, such as gene expression, providing a versatile alternative to chemical inducers. (nih.gov)
Used Molecular Genes from Filamentous Fungus. (kedroom.ru)

investigated the fungus at the level of gene expression, and performed proteome-level studies ( Yajima and Kav, 2006 ). (frontiersin.org)

Such fermentation is a good example of the industrial use of filamentous fungi's ability to secrete various enzymes in large quantities. (asiaresearchnews.com)
Consequently, studies have been conducted to utilize filamentous fungi as a prominent source of enzymes for plant biomass degradation. (asiaresearchnews.com)
These findings address the current technology challenge in establishing a much-wanted comprehensive high production method for various enzymes in filamentous fungi. (asiaresearchnews.com)
Mining for enzymes, researchers can figure out the classes that BGCs encode and compare target gene clusters to known gene clusters. (wikipedia.org)
Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation. (nature.com)
This is usually achieved through inhibition of gene expression of enzymes involved in the catabolism of other carbon sources than the preferred ones. (biomedcentral.com)

A) Suppression of nud mutants by extra copies of the nudE and nudF6 genes. (xenbase.org)
Expression of the β-xylanase genes in the presence of D-glucose was de-repressed in all the deletion mutants, with significantly higher tolerance against D-glucose repression in Δ pkaA and Δ ganB than in Δ creA . (megazyme.com)

A growing resistance in pathogenic fungi to standard antifungal products results in major crop losses each year. (boisestate.edu)
Pathogenic Fungi-Structural Biology and Taxonomy is an important interpretation of recent literature, a valuable addition to collections, and recommended reading for investigators seeking a broad appreciation for the current state of the art. (cdc.gov)

Thus, the discovery of antifungal "killer toxins" naturally produced by fungi has spurred interest in their use against diseases such as Fusarium wilt. (boisestate.edu)
Fusarium graminearum is a filamentous fungus that is the primary causal agent of the disease Fusarium head blight (FHB) on cereal crops. (msu.edu)

The series' scope is to review progress in basic research on zoopathogenic fungi, a timely effort as medical mycology moves into the genomics era. (cdc.gov)

Unique features of these groups are that Basidiomycetes have more complex mating type systems consisting of much more polymorphic mating types and a pheromone/pheromone receptor system, and (filamentous) Ascomycetes have a somatic (heterokaryon) incompatibility system in addition to the sexual mating types. (tripod.com)
Development of primer sets designed for use with the PCR to amplify conserved genes from filamentous ascomycetes. (cdc.gov)

The following NCU01377 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). (genscript.com)
In this study, a suppression subtractive hybridization cDNA library approach was used for the identification of pathogen and plant genes that were differentially expressed during infection of the susceptible cultivar BRS Pérola of Phaseolus vulgaris L. A total of 979 unigenes (430 contigs and 549 singletons) were obtained and classified according to their functional categories. (frontiersin.org)

A number of plant labs develop and use new approaches to assess how plants, fungi and microbes interact. (nature.com)
Instead, Kiers and her colleagues look at the diversity of strategies, such as those that shape the interaction of plants and microbes, especially fungi. (nature.com)

Our results provide better understanding on intron retention, the NMD pathway, and cellulase production mechanism in filamentous fungi. (researchsquare.com)

Currently, 16S rRNA gene sequence analysis and MALDI-TOF mass spectrometry are both precise diagnostic methods adopted by multiple laboratories. (medscape.com)

Proteomic analysis indicated that the expression of CAZymes in P. parvum varied between CBAX1 and CBR, and the fungus produced complete cellulases, numerous hemicellulases, as well as high levels of glycosidases under the culture conditions. (biomedcentral.com)

The filamentous strain had no dissemination, and cecal colonization was significantly less than that of the other 2 strains. (medscape.com)

The CYS-3 transcription factor bound the promoters and regulated genes involved in sulfur metabolism. (escholarship.org)
Sulfur starvation also caused changes in the expression of genes involved in carbohydrate metabolism, such as those encoding glycosyl hydrolases. (escholarship.org)
Along with genes involved in sulfur metabolism, this transcription factor regulated a number of uncharacterized transporter genes and genes involved in mitochondrial electron transfer. (escholarship.org)

The biological functions of intron retention (IR) and nonsense-mediated mRNA decay (NMD) in filamentous fungi is lack of study, let alone their roles in cellulase biosynthesis. (researchsquare.com)
In the presence of the NMD pathway inhibitor that successfully repressed the NMD pathway, the mRNA levels of cellulase genes were sharply down-regulated, but the rates of IR in these genes were significantly up-regulated. (researchsquare.com)
In addition, the NMD pathway inhibitor caused the downregulated mRNA levels of two important genes of the target of rapamycin (TOR) pathway, trfkbp12 and trTOR1 . (researchsquare.com)

Mutations also are crucial devices inside unit hereditary training and you may gene manipulation. (kedroom.ru)

The enhancement of food safety and biosecurity by developing new methods for the analysis of filamentous fungi colonizing foods and new strategies to reduce or eliminate toxin contamination-either plant or animal origin commodities-is of great importance. (mdpi.com)

The nuclei of most fungi are haploid except when a zygote is formed in sexual reproduction. (tripod.com)

In addition, introduction of C albicans strains with 2 functional copies of the INT1 gene increased the number of fungi colonizing the cecum and disseminating to extraintestinal sites. (medscape.com)
To further examine the role of yeast and filamentous forms, researchers intravenously or orally infected antibiotic-treated and dexamethasone-treated mice using 3 strains of C albicans: (1) a wild-type strain that had both yeast cell and filamentous forms, (2) a strain with only yeast cells, and (3) a strain that was constitutively filamentous. (medscape.com)

The N-terminal sequence, 23 residues long, was used to design a gene-specific primer. (microbiologyresearch.org)

1993). Controls out-of sulfur and you may nitrogen metabolic process within the filamentous fungus. (kedroom.ru)

Dexamethasone plus antibiotics led to an increase in the percentage of filamentous forms in the GI tract compared with antibiotics alone. (medscape.com)

as well as to estimate the presence and absence of the PCR products corresponding to amplification of aflD , aflM , aflP , aflR , and aflS genes in aflatoxigenic and nonaflatoxigenic A. flavus isolates isolated from stored cashew. (hindawi.com)

The morphology and development of the filamentous fungi are influenced by various factors because the tradition situations and the kind of fermentative course of. (todaytopics.com)

In sexually reproducing fungi, there is no distinction between male and female structures but there is a genetically determined difference among individual fungi. (tripod.com)
Of many fungi off commercial desire was indeed read genetically consequently they are offered to reproduction. (kedroom.ru)

Its low effective concentration towards fungi, ranging from 0.1 to 10 μM and its safety to mammals and birds makes them a better choice, in place of chemicals, to control fungi infection on crop fields. (frontiersin.org)

Fine tuning of morphogenesis is illustrated by the "enhanced filamentous growth" gene which, when knocked out, blocks the transition to the mycelial form. (cdc.gov)
Departing from the morphogenesis theme, chapters on phylogenetic analysis help clarify the taxonomy of noncultivatable medical fungi (excluding Pneumocystis ). (cdc.gov)

CYS-3 also directly regulated the expression of genes involved in mitochondrial electron transfer. (escholarship.org)

The main software often, but not, be in biotechnology, in which an excellent concerted use of mutation, gene control, and you may traditional recombination contains the finest perspectives. (kedroom.ru)

The absence of a functional INT1 gene diminishes adherence in yeast cells but not filamentous forms. (medscape.com)

Anatomy12

Organisms82

Diseases9

Chemicals and Drugs71

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Phenomena and Processes51

Disciplines and Occupations5

Technology, Industry, Agriculture9

Information Science4

Health Care7

Aspergillus14

Fungal12

Neurospora5

Microorganisms7

Yeasts4

Anserina2

Bacteria2

Trichoderma6

Target genes2

Ustilago2

Mechanisms9

Proteins4

Magnaporthe1

Pathogenicity1

Genera1

Regulation6

Identified genes involved1

Regulates5

Pathways3

Hyphae2

Biosynthetic5

Genome sequence1

Species6

Genetic3

Organisms3

Secondary metabolites1

Protein7

Plasmids2

Characterize2

Molecular2

Level of gene expression1

Enzymes6

Mutants2

Pathogenic2

Fusarium2

Mycology1

Ascomycetes2

CDNA2

Microbes2

Mechanism1

RRNA1

Cellulases1

Colonization1

Metabolism3

MRNA3

Mutations1

Analysis of filamentous1

Nuclei1

Albicans2

Sequence1

Metabolic1

Antibiotics1

Amplification1

Morphology1

Genetically2

Infection1

Morphogenesis2

Mitochondrial1

Biotechnology1

Yeast cells1