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  • infection
  • The aim of the present study was to determine genotypes of SNPs in the IL4 , IL13 and IFNG genes and of 21 additional SNPs significantly associated with immune traits in white and brown commercial layer lines and to analyze their association with worm numbers resulting from a natural helminth infection in order to identify gene regions as promising candidates for further studies on parasite resistance in chickens. (biomedcentral.com)
  • miRNAs
  • We find that miRNA members belonging to families are more likely to be expressed in overlapping tissues than miRNAs that do not belong to the same family, and provide evidence that intronic miRNAs may be controlled by their own, rather than a host gene promoter. (umassmed.edu)
  • Interference
  • By using an in vivo time-lapse differential interference contrast microscopy assay, we identified 133 genes (approximately 6%) necessary for distinct cellular processes in early embryos. (mdc-berlin.de)
  • immune
  • Single nucleotide polymorphisms (SNPs) in the genes for interleukin-4, -13 and interferon-gamma, and 21 additional SNPs which previously had been significantly associated with immune traits in the chicken, were genotyped in white and brown layer hens and analyzed for their association with helminth burden following natural infections. (biomedcentral.com)
  • 7. IgA Nephropathy GWAS implicates genes involved in helminth immune response (7%)- This was the surprise of the year in my opinion. (blogspot.com)
  • novel
  • A further characterization of novel M. incognita genes could begin by examining those with longer ORFs as these are most likely to be real coding regions. (nih.gov)
  • analysis
  • Genes and gene products do not function in isolation but within highly interconnected 'interactome' networks, modeled as graphs of nodes and edges representing macromolecules and interactions between them, respectively.Using ced-9 edgetic alleles, we uncovered a new potential functional link between apoptosis and a centrosomal protein.This approach is amenable to higher throughput and is particularly applicable to interactome network analysis in organisms for which transgenesis is straightforward. (nih.gov)
  • function
  • Genes and gene products do not function in isolation but within highly interconnected 'interactome' networks, modeled as graphs of nodes and edges representing macromolecules and interactions between them, respectively. (nih.gov)
  • From these, 1,625 EST clusters were formed and classified by function using the Gene Ontology (GO) hierarchy and the Kyoto KEGG database. (nih.gov)
  • different
  • The estimated heritabilities for worm burdens of the different helminths and of the total worm burden ranged from 0.11 to 0.69 in LB and from 0.01 to 0.30 in LSL. (biomedcentral.com)
  • OmicsNet build interaction networks starting from list(s) of input molecules: gene/protein, TF, miRNA and metabolite and supports the integration of up to three different interaction types. (omicsnet.ca)
  • results
  • Ratio-intensity (R-I) scatter plot depicting the results of oligonucleotide microarray comparing gene expression between mature sexual planarians (Sx) and asexual (Asex) planarians. (nih.gov)
  • development
  • Collectively, these cell-type specific markers will enable future efforts to characterize genes that are important for reproductive development in the planarian. (nih.gov)
  • however
  • however, variants of interleukin-4 ( IL4 ), interleukin-13 ( IL13 ) and interferon-gamma ( IFNG ) genes were not included. (biomedcentral.com)
  • Program
  • This allows for the induction of a transcriptional program that encodes hallmark genes such as Il1b, Il6 , and TNFa . (frontiersin.org)
  • suggest
  • Moreover, heritabilities estimated for parameters of susceptibility to helminthic infections, as mean worm or larvae counts [ 6 - 10 ], suggest that it is possible to select for helminth resistance in poultry. (biomedcentral.com)
  • cell
  • Genetically engineered T cells are created by harvesting T cells and then infecting the T cells with a retrovirus that contains a copy of a T cell receptor (TCR) gene that is specialised to recognise tumour antigens. (wikipedia.org)
  • Single
  • These questions are frequently not addressable by examining a single gene or a single pathway, but can best be addressed at the systems level. (denigma.de)
  • Strain
  • Alcohol preference may be associated with strain differences in mesolimbic enkephalin gene expression (Ng et al, 1996). (spotidoc.com)
  • A quasi-congenic QTL introgression strain carrying a low alcohol consumption gene from BALB/c has lower voluntary alcohol consumption than C57BL/6, with 96% of loci in common (Vadasz et al, 1996). (spotidoc.com)
  • expression
  • The Administration of Intranasal Live Attenuated Influenza Vaccine Induces Changes in the Nasal Microbiota and Nasal Epithelium Gene Expression Profiles. (nyu.edu)
  • Binding of beta-catenin to T cell factors (Tcfs) in the nucleus forms a transcriptional activation complex that induces the expression of cell type-specific target genes, ultimately regulating the size of the scar remaining after wound repair. (immunopaedia.org.za)
  • Type
  • Although the causes of peripheral blood eosinophilia are numerous, the vast majority of cases are due to production of interleukin-5 (IL-5) by T helper type 2 (TH2) lymphocytes secondary to allergic conditions (e.g., asthma, rhinitis), parasitic infections (especially helminths), and drug reactions (e.g., cephalosporins, allopurinol, synthetic penicillins). (oncologynurseadvisor.com)