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  • genetic
  • The physical appearance of a child is ultimately the result of his or her genetic makeup, which itself is the product of the combined genes received from the parents. (apologeticspress.org)
  • For example, there are two genetic variations that can lead to male sterility in S. latifolia: if it possesses two Y chromosomes (YY) or if the Y chromosome possesses the female suppression and male promoting genes. (wikipedia.org)
  • The other genetic mechanism is derived from the silver dapple gene, which lightens a black coat to dark brown, and affects the mane and tail even more strongly, diluting to cream or near-white. (wikipedia.org)
  • expression
  • for example, some posit it is programmed by gene expression changes, others that it is the cumulative damage caused by biological processes. (wikipedia.org)
  • Although senescent cells can no longer replicate, they remain metabolically active and commonly adopt an immunogenic phenotype consisting of a pro-inflammatory secretome, the up-regulation of immune ligands, a pro-survival response, promiscuous gene expression (pGE) and stain positive for senescence-associated β-galactosidase activity. (wikipedia.org)
  • horses
  • Feral horse herds, like those of wild horses, are usually made up of small bands led by a dominant mare, containing additional mares, their foals, and immature horses of both sexes. (wikipedia.org)
  • Coat
  • The presence of the sooty gene may result in a palomino having darker hairs in the mane, tail and coat. (wikipedia.org)
  • Cremellos carry two copies of the cream gene and have a light mane and tail but also a cream-colored hair coat, rosy pink skin and blue eyes. (wikipedia.org)
  • Buckskin is also created by the action of a single cream gene, but on a bay coat. (wikipedia.org)
  • human
  • The EUBREC_0645 gene translates into the YP_002936568 protein from Eubacterium rectale , the most abundant member of Firmicutes phyla in the human gut, and it is the first solved representative of the bacterial TIR-like domain family (DUF1863/PF08937, e-value=0.00017). (burnham.org)
  • known
  • Recent studies have shown that a critical gene for gender determination in Drosophila known as the sex-lethal gene is highly misregulated in D. melanogaster and D. simulans hybrids, compared with the degree of misregulation of non-sex biased genes studied. (wikipedia.org)
  • The gene causing this condition is not yet known. (wikipedia.org)
  • Although it was known most of the 20th century that most cases of haemochromatosis were inherited, they were incorrectly assumed to depend on a single gene. (wikipedia.org)
  • type
  • E D (dominant black), E S (steel, weaker version of E D ), E (wild type, normal extension of black), e J (Japanese brindling, mosaic distribution of black and yellow) and e (non-extension of black, yellow/red with white belly). (biomedcentral.com)
  • presence
  • Another possible combination includes the presence of all three sex-linked genes (male suppressing, female suppressing, and male promoting) which produce virile male offspring. (wikipedia.org)
  • often
  • A horse with rosy-pink skin and blue eyes in adulthood is most often a cremello or a perlino, a horse carrying two cream dilution genes. (wikipedia.org)
  • When crossed with a single cream gene, the resulting horse, often called a "pseudo-double-dilute", appears visually to be a cremello. (wikipedia.org)
  • cell
  • The genes that currently have evidence to be associated with CMM disorder include DCC (deleted in colorectal carcinoma), DNAL4 (dynein axonemal light chain 4), and RAD51 (recombination protein A). DCC encodes a receptor for NTN1 (netrin-1), a protein thought to be responsible for axon guidance and neuronal cell migration during development. (wikipedia.org)
  • male
  • Two of these sex-linked genes "promote maleness" (male fertility and male promotion) and one of them codes for female suppression. (wikipedia.org)
  • state
  • Tracing their roots to the village of Kilaneh, the Sanandaji family, which since the Islamic Revolution in 1979 have moved to Europe and the United States, were the dominant land and farm owners in the state of Kurdistan throughout its modern history. (wikipedia.org)
  • disease
  • Despite being autosomal dominant, it is important to note that the disease has variable expressivity. (wikipedia.org)
  • In a patient with negative HFE gene testing, elevated iron status for no other obvious reason, and family history of liver disease, additional evaluation of liver iron concentration is indicated. (wikipedia.org)
  • total
  • Results: The VDR gene polymorphisms were genotyped in a total of 50 individuals with ALL, comparing 50 normal children with a mean age of 5.2±3.4 years. (ijbc.ir)
  • children
  • We aimed to investigate rs731236 polymorphism of VDR gene in children with ALL. (ijbc.ir)
  • Conclusion: We have determined the frequency of Taq1 (rs731236) polymorphism in the VDR gene in children with ALL in Zanjan population. (ijbc.ir)
  • Ale Ahmad A, Saburi E, Rajaei T, Mortazavi Y. Taq1 Polymorphism (rs731236) of Vitamin D Receptor Gene in Children with Acute Lymphoblastic Leukemia. (ijbc.ir)
  • five
  • His rationale was [that] B is the 'five chord,' or dominant chord, to the key of E. This resulted in absolutely-to-Pete steel licks. (wikipedia.org)
  • Source
  • Plants are a dominant component of terrestrial ecosystems and are the source of energy for the majority of other terrestrial organisms. (psu.edu)
  • families
  • Silene recently evolved sex chromosomes 5-10 million years ago and are widely used by geneticists and biologists to study the mechanisms of sex determination since they are one of only 39 species across 14 families of angiosperm that possess sex-determining genes. (wikipedia.org)
  • test
  • The definitive test is sequencing the whole Notch 3 gene, which can be done from a sample of blood. (wikipedia.org)
  • example
  • For example, the Haflinger breed has many light chestnuts with flaxen that may superficially resemble dark palomino, but there is no cream gene in the breed. (wikipedia.org)
  • retinal
  • The treatment works by silencing, or "knocking down," the defective copies of the rhodposin gene and, at the same time, delivering normally functioning copies of the gene to retinal cells. (blindness.org)
  • We conclude that rare missense variations in most of these genes identified in individuals with retinal dystrophy cannot be confidently classified as disease-causing in the absence of additional information such as linkage or functional validation. (molvis.org)
  • genome
  • This uncertainty is evident at the single gene level, but has become a major hurdle for multigene sequencing panels [ 5 ] and can compromise whole genome or whole exome testing if not properly addressed. (molvis.org)
  • locus
  • Often mistaken for a "double merle", a harlequin merle (or just harlequin), is a dog that carries both the merle pattern gene and the co-dominate modifying gene (carried on a different locus) for harlequin. (wikipedia.org)
  • Identification
  • Identification of a Dominant Gene in Medicago truncatula That Restrict" by Jinge Liu, Shengming Yang et al. (uky.edu)
  • Although identification of a novel or extremely rare variant in a patient with an IRD in one of these genes should be evaluated as a putative disease-causing variant, the clinical validity of such a causative relationship can be difficult to assess. (molvis.org)
  • variation
  • As newly available gene panel sequencing and whole exome sequencing will open these genes up to greater scrutiny, we assess the rate of rare coding variation in these genes among unaffected individuals to provide context for variants that will be discovered when clinical subjects are sequenced. (molvis.org)
  • occur
  • As it so happens, when you change one gene just a little, there is often a cascade of other changes that occur as a result. (stormfront.org)
  • proteins
  • The gene codes for two proteins, including the INK4 family member p16 (or p16INK4a) and p14arf. (wikipedia.org)
  • This gene encodes two proteins, p16 and p14ARF, which are transcribed from the same second and third exons but alternative first exons: p16 from exon 1α and ARF from exon 1β. (wikipedia.org)
  • chromosomal
  • After some years of research from the University of Kentucky, in 2008 the chromosomal inversion that affects regulatory regions of the KIT gene was discovered. (wikipedia.org)
  • regulatory
  • The migration of nerve- and melanocyte-precursors from the top of the embryo to their eventual destinations is carefully controlled by regulatory genes. (wikipedia.org)
  • Such regulatory genes include endothelin receptor type B (EDNRB). (wikipedia.org)
  • Disease
  • As a cause of dominant disease, the gene can get passed down from generation to generation. (blindness.org)
  • The spontaneous mouse mutant Dominant megacolon (Dom) is a valuable model for the study of human congenital megacolon (Hirschsprung disease). (mysciencework.com)
  • These results identify the transcriptional regulator Sox10 as an essential factor in mouse neural crest development and as a further candidate gene for human Hirschsprung disease, especially in cases where it is associated with features of Waardenburg syndrome. (mysciencework.com)
  • The CDKN2A gene also contains one of 27 SNPs associated with increased risk of coronary artery disease. (wikipedia.org)
  • phenotypic
  • We aimed to investigate the impact of this phenotypic heterogeneity on successfully finding new genes that are involved in ADH. (bmj.com)
  • coat
  • Expression of the panda gene is exhibited openly on any coat that is not already white. (wikipedia.org)
  • A dilute black (BB or Bb) dog is generally known as blue, but a dog with a merle coat does not test BB or Bb but still is a blue dilute from the "merle" gene The merle gene creates mottled patches of color in a solid or piebald coat, blue or odd-colored eyes, and can affect skin pigment as well. (wikipedia.org)
  • carries
  • The coloration is present from birth and does not change throughout the horse's lifetime, unless the horse also carries the gray gene. (wikipedia.org)
  • naturally
  • RESULTS: We screened a core collection of Medicago truncatula genotypes with several strains of Sinorhizobium meliloti and identified a naturally occurring dominant gene that restricts nodulation by S. meliloti Rm41. (uky.edu)
  • Because it was discovered in naturally occurring populations of cats, the Manx gene could confer some kind of selective advantage to the cats, or it may simply be an example of the founder effect. (wikipedia.org)
  • order
  • This means they only need one copy of a gene to be present in order to be expressed. (stormfront.org)
  • These findings provide a basis for the revision of our assessment on who is affected and who is not and emphasise the essence of pedigree information and mapping data before exome sequencing is applied in order to increase success rates of finding new genes related to ADH. (bmj.com)
  • Horses
  • One theory holds that such horses carry the frame gene, but so minimal in expression that they appear solid. (wikipedia.org)
  • marker
  • The gene, designated as CMD2 , is flanked by the SSR and RFLP marker GY1 at 9 and 8 cM, respectively. (springer.com)
  • color
  • John's Wort with Ginkgo Biloba is an effective natural treatment for mild depression LifeTek St John's St. Color Blindness Dominant Gene Liver Damage Vitamin you may have pain and increased sensitivity to light. (kojoti.eu)
  • structure
  • To enhance execution and boost performance, most managers have traditionally focused most of their attention on the structure gene. (pwc.com)
  • cases
  • In many cases people are not aware that they carry a relevant gene until they have children who begin to show signs of having the disorder. (wikipedia.org)