• ARV1 is ubiquitously expressed in higher eukaryotes, and in Saccharomyces cerevisiae yeast, is required for viability. (wikipedia.org)
  • Researchers from Canada, Sweden, and the US present findings from a functional screen of nearly 200 genetic variants in 22 genes implicated in human disease in the budding yeast assay Saccharomyces cerevisiae . (genomeweb.com)
  • Saccharomyces cerevisiae cells lacking the MDM12 gene product display temperature-sensitive growth and possess abnormally large, round mitochondria that are defective for inheritance by daughter buds. (rupress.org)
  • The RAD6 gene of the yeast Saccharomyces cerevisiae is required for DNA repair, for DNA damage-induced mutagenesis, and for sporulation, and it encodes a ubiquitin-conjugating enzyme. (eur.nl)
  • Saccharomyces cerevisiae (commonly known as baker's yeast) is a single-celled eukaryote that is frequently used in scientific research. (jove.com)
  • Saccharomyces cerevisiae , otherwise known as baker's yeast, is one of the many model organisms studied in laboratories all over the world. (jove.com)
  • Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae. (rhea-db.org)
  • The catabolic L-serine (L-threonine) dehydratase of Saccharomyces cerevisiae allows the yeast to grow on media with L-serine or L-threonine as sole nitrogen source. (unipr.it)
  • In the budding yeast Saccharomyces cerevisiae , the minimal transport machinery includes the membrane proteins Pex13 and Pex14 and the cargo-protein-binding transport receptor, Pex5. (tcdb.org)
  • We will also discuss potential approaches to humanize yeast in order to create modification patterns resembling the situation in mammalian cells, which could enhance the value of Saccharomyces cerevisiae and Kluyveromyces lactis as disease models. (microbialcell.com)
  • The SEB1/SBH1 and the SSO genes encode components of the protein secretory machinery functioning at the opposite ends, ER translocation and exocytosis, respectively, of the secretory pathway in Saccharomyces cerevisiae. (vtt.fi)
  • A yeast complementation assay showed that heterologous expression of NcACBP rescued the phenotypic defects in Δacbp yeast, indicating of the binding activity of NcACBP in vivo . (biomedcentral.com)
  • Furthermore, OsDXR interacted with the RNA editing factor OsMORF1 in a yeast two-hybrid screen and bimolecular fluorescence complementation assay. (chinaagrisci.com)
  • The H2A.Z loss of function mutant, M6-G98N, was used in a complementation assay using a yeast genomic expression library to identify suppressors of the mutant. (usherbrooke.ca)
  • A large library of HMBS missense variants was assessed with respect to their effects on protein function using a high-throughput yeast complementation assay. (genomeinterpretation.org)
  • Complementation of the yeast ybr 159Δ mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene. (unl.edu)
  • We have cloned the RAD6 homolog from Drosophila melanogaster and find that its encoded protein displays a very high degree of identity in amino acid sequence with the homologous RAD6 proteins from the two divergent yeasts, S. cerevisiae and Schizosaccharomyces pombe, and from human. (eur.nl)
  • We prove that our approach can not only be used for integration of complementation cassettes, but also for overexpression of markers like fluorescent proteins and the antigen ovalbumin, or of potential pathogenicity-related factors like the biotin transporter gene VHT1. (leibniz-hki.de)
  • Because many yeast proteins are similar in sequence and function to those found in other organisms, studies performed in yeast can help us to determine how a particular gene or protein functions in higher eukaryotes (including humans). (jove.com)
  • Interestingly, many proteins found in yeast share similar sequences with proteins from their fellow Eukaryotes. (jove.com)
  • To find their function we need an expression profile of each gene and since the function of MADS-box proteins is often achieved by forming complexes, we will identify interaction partners of the E-class genes. (edu.au)
  • Previous studies have shown that ClpB-cyt/HSP100 gene belongs to the group class I Clp ATPase proteins and ClpB-cyt/HSP100 transcript is regulated by heat stress and developmental cues. (biomedcentral.com)
  • The exocyst complex, a set of eight proteins first identified from secretory mutants in yeast, is an attractive candidate for mediating directed traffic. (sdbonline.org)
  • The majority of ERG genes downstream of zymosterol (ERG6 ERG2 ERG3 ERG5 and ERG4) showed little or no sequence homology with human genes (KEGG pathways (17)) HMN-214 but instead proteins with unrelated sequence performed comparable enzymatic activities. (bioinf.org)
  • For this we used the yeast sterol pathway proteins as seeds to mine data from large-scale yeast genetic arrays (18) affinity purification and mass spectroscopy resolution of protein complexes (19-21) and protein complementation screens (22) to gain further insight into their function (Physique S4 Table S1 and supplemental Cytoscape file). (bioinf.org)
  • The network generated for ERG25 ERG26 ERG27 ERG28 proteins (Fig. 3A S4) revealed as expected many interactions reflecting their participation in the linear ergosterol biosynthesis pathway (green circles in Fig. 3A) as well as additional interactions with genes annotated for functions in lipid synthesis and metabolism. (bioinf.org)
  • Unexpectedly multiple genetic and protein-protein interactions were HMN-214 also detected between and proteins with Gene Ontology (GO) annotations indicating direct involvement HMN-214 in vesicular transport secretory pathway and cellular localization: of 178 ERG25-interacting proteins 53 had such GO annotations representing a highly significant enrichment (e.g. vesicle-mediated transport p=1.4*10?8) (Fig. 3B). (bioinf.org)
  • Over two dozen proteins involved in protein import and membrane insertion, peroxins, encoded by PEX genes, have been characterized. (tcdb.org)
  • In yeast a single complex of three proteins termed HAP2 HAP3 and HAP5 binds to this sequence and in mammals the three components of the equivalent complex (called variously NF-Y CBF or CP1) are also represented by single genes. (camregbase.org)
  • In the past decade, yeast have been frequently employed to study the molecular mechanisms of human neurodegenerative diseases, generally by means of heterologous expression of genes encoding the relevant hallmark proteins. (microbialcell.com)
  • In this respect, although obviously lacking a brain with a multicellular neuronal network, simple unicellular yeast are of great value to investigate the effects of overexpression and single point-mutations in genes encoding key proteins on cell physiology and on the function of conserved signaling cascades. (microbialcell.com)
  • Furthermore, their overexpression in wild‐type yeast enhances production of secreted proteins in S. cerevisiae, which suggests that they may be rate‐limiting factors in this process. (vtt.fi)
  • In accordance with the high homology level of the secretory pathway proteins in different yeast species, the polyclonal antibodies raised against S. cerevisiae Seb1p, Sso2p and Sec4p can detect homologous proteins in cell lysates of K. lactis and Pichia pastoris, the latter also in Candida utilis. (vtt.fi)
  • Many of the yeast subunits are homologs to proteins in higher organisms that are found associated with specific nuclear receptors such as THYROID HORMONE RECEPTORS and VITAMIN D RECEPTORS. (bvsalud.org)
  • Functional assessments of NADSYN1 missense variants, through a combination of yeast complementation and enzymatic assays, show impaired enzymatic activity and severely reduced NAD levels. (bepress.com)
  • Functional complementation demonstrated that HpDGAT2A, HpDGAT2B, HpDGAT2D, and HpDGAT2E had the capacity to restore TAG synthesis in a TAG-deficient yeast strain (H1246) showing a large difference in enzymatic activity. (researchsquare.com)
  • Our study represents systematic work on the characterization of HpDGAT2s by integrating expression patterns, AST/TAG accumulation, functional complementation, and heterologous expression in yeast, plants, and algae. (researchsquare.com)
  • After looking at how well human disease genes rescued the activity of temperature sensitive versions of orthologous yeast genes, the team came up with a set of 26 functional assays for evaluating human disease gene activity, including assays based on 19 complementation relationships not reported previously. (genomeweb.com)
  • When expressed in S. cerevisiae , the S. pombe Mdm12p homolog conferred a dominant-negative phenotype of giant mitochondria and aberrant mitochondrial distribution, suggesting partial functional conservation of Mdm12p activity between budding and fission yeast. (rupress.org)
  • For further functional analysis, TdATG8 protein was expressed in yeast and analyzed using Western immunoblotting. (sabanciuniv.edu)
  • In summary, this project will ideally suit an enthusiastic student who is interested in learning more about functional gene research combined with molecular biology, biochemistry, cell biology, and developmental biology. (edu.au)
  • Moreover, the functions of PaWB-related genes were predicted by functional enrichment analysis, and two genes related to maintenance of the basic mechanism of stem cells in shoot apical meristem were discovered. (bvsalud.org)
  • Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD). (yeastgenome.org)
  • Since htz1 _ cells were highly sensitive to hydroxyurea, we used this reagent for screening functional complementation. (usherbrooke.ca)
  • Three independent Arabidopsis HAP subunit 2 (AtHAP2) cDNAs were cloned by functional complementation of a yeast hap2 mutant and two independent forms each of AtHAP3 and AtHAP5 cDNAs were detected in the expressed sequence tag database. (camregbase.org)
  • Acyl-coA acyltransferase-related enzyme 2 required for viability is a protein that in humans is encoded by the ARV1 gene. (wikipedia.org)
  • Students will gain first-hand experience in modern cytological approaches such as epitope tagging and imaging yeast cells using fluorescence microscopy with GFP-protein fusions and fluorescent indicators for different subcellular structures and organelles. (cshl.edu)
  • Finally, the video describes some of the many ways in which yeast cells are put to work in modern scientific research, including protein purification and the study of DNA repair mechanisms and other cellular processes related to Alzheimer's and Parkinson's diseases. (jove.com)
  • By investigating the function of a given protein in yeast, researchers gain insight into the protein's function in higher eukaryotes, such as us, humans. (jove.com)
  • The recombinant NcACBP protein was expressed to verify the binding activities of NcACBP in vitro , and the heterologous expression of NcACBP in Δacbp yeast in vivo . (biomedcentral.com)
  • From the complementation assays, OsClpD1 appears to be more effective than OsClpB-cyt protein in rescuing the thermosensitive defect of the yeast ScΔhsp104 mutant cells. (biomedcentral.com)
  • One of the genes encodes the receptor protein kinase CLV2 (Paulownia_LG2G000076), and the other gene encodes the homeobox transcription factor STM (Paulownia_LG15G000976). (bvsalud.org)
  • Four mutant complementation groups were characterized that correspond to respective mutations in genes encoding Ran (gsp1), and essential Ran regulatory factors Ran GTPase-activating protein (rna1), Ran guanine nucleotide exchange factor (prp20), and the RanGDP import factor (ntf2). (tamu.edu)
  • Overexpression of these genes can rescue temperature‐sensitive (ts) growth defect of many sec mutants impaired in protein secretion. (vtt.fi)
  • Interestingly, KlSSO1 and KlSEB1 show similar enhancing effect on production of a secreted protein as the SSO and SEB1 genes of S. cerevisiae when overexpressed. (vtt.fi)
  • The introduction of a normal, or wild type, copy of the proposed gene - referred to as BRUSH - into the brush mutant did not correct the problems with its roots. (elifesciences.org)
  • kan MX yeast mutant strain grown under nitrogen deficiency. (sabanciuniv.edu)
  • However, the gene expression and activity of antioxidative enzymes had no differences between wild type and the zcf29zcf29 mutant. (ncl.edu.tw)
  • In addition, the expression of ERG2, ERG24 and ERG11 genes and the ergosterol content had no differences between wild type and the mutant. (ncl.edu.tw)
  • Complementation assays of Δhsp104 mutant yeast cells showed that OsClpB-cyt , OsClpB-m , OsClpC1 and OsClpD1 have significantly positive effects. (biomedcentral.com)
  • Remarkably, OsClpD1 gene imparted appreciably high level tolerance to the mutant yeast cells. (biomedcentral.com)
  • By the complementation of a yeast mutant defective in myo-inositol transport (Nikawa, J., Nagumo, T., and Yamashita, S. (1982) J. Bacteriol. (rhea-db.org)
  • Previously we have cloned the CHA1 gene by complementation of a mutant, cha1, lacking the dehydratase activity. (unipr.it)
  • Transcription analysis showed that the expression levels of the HpDGAT2A , HpDGAT2D , and HpDGAT2E genes markedly increased under high light and nitrogen deficient conditions with distinct patterns, which led to significant TAG and EAST accumulation. (researchsquare.com)
  • A group from the US and Russia reports on gene expression regulatory differences detected in ecotypes of the perennial C4 grass Panicum hallii that have become more or less drought adapted. (genomeweb.com)
  • The researchers considered leaf gene expression patterns in a lowland variety of the grass called P. hallii var. (genomeweb.com)
  • In many cases, the disease gene encodes a component of phototransduction or allied processes with expression confined to the retina, for example the rod visual pigment (reviewed in [ 1 ]), or peripherin-RDS [ 2 ], but not all RP genes show such a restricted pattern of expression. (molvis.org)
  • Expression analyses showed that both AtKCR1 and AtKCR2 genes were transcribed in siliques, flowers, inflorescence stems, leaves, as well as developing embryos, but only AtKCR1 transcript was detected in roots. (unl.edu)
  • A TRP1-marker-based system for gene complementation, overexpression, reporter gene expression, and gene modification in Candida glabrata. (leibniz-hki.de)
  • Sprenger M, Brunke S, Hube B, Kasper L (2021) A TRP1-marker-based system for gene complementation, overexpression, reporter gene expression, and gene modification in Candida glabrata . (leibniz-hki.de)
  • With urea amidolyase Dur1,2 as an example, we demonstrate the application of the gene complementation approach for the expression of sequence-modified genes. (leibniz-hki.de)
  • In this project we will study the expression and function of these E-class MADS -box genes in barley. (edu.au)
  • This honours project will involve in both the MADS box genes' expression and regulatory network in morphogenesis and development of inflorescence and spikelet of barley at SJTU (Shanghai Jiao Tong University) & UoA Joint Laboratory for Plant Sciences and breeding. (edu.au)
  • Furthermore, transcriptome analysis was performed to compare the gene expression in different strains. (biomedcentral.com)
  • The loss of NcACBP resulted in global changes in the expression of multiple genes. (biomedcentral.com)
  • Therefore, the dramatic changes of sugar type and concentration during the germination process undoubtedly regulates the enzyme activity and the pattern of gene expression of several enzymes [ 5 , 6 ]. (biomedcentral.com)
  • Participation of nuclear genes in chloroplast gene expression. (chinaagrisci.com)
  • Expression and molecular analysis of the Arabidopsis DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the first committed enzyme of the 2-C-methyl-D-erythritol 4-phosphate pathway. (chinaagrisci.com)
  • A set of reliable reference genes is essential for accurate quantification and interpretation of gene expression data using reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). (mpob.gov.my)
  • The expression levels of these genes were compared and evaluated using geNorm. (mpob.gov.my)
  • Three genes (EgREF_5, EgREF_7 and EgREF_11) were found to be appropriate reference genes for normalising gene expression data from both mature plant and tissue culture samples. (mpob.gov.my)
  • This poses the important question, which of these posttranslational modifications are naturally occurring in the yeast model or can be reconstituted by heterologous gene expression. (microbialcell.com)
  • Students will learn genome-based methods of analysis facilitated by the yeast genome sequence, the gene deletion collection, and other genomic resources available to the community. (cshl.edu)
  • In this study, we established a gene complementation strategy using genomic integration at the TRP1 locus. (leibniz-hki.de)
  • Characterization of the Wilson disease gene encoding a P type copper transporting ATP ase: genomic organization, alternative splicing and structure/function predicting. (9lib.net)
  • Fatty acid (FA) profile assays revealed that HpDGAT2A, HpDGAT2D, and HpDGAT2E, but not HpDGAT2B, preferred monounsaturated fatty acyl-CoAs (MUFAs) for TAG synthesis in yeast cells, and showed a preference for polyunsaturated fatty acyl-CoAs (PUFAs) based on their feeding strategy. (researchsquare.com)
  • The investigators then used these assays to begin evaluating the potential pathogenicity of 179 disease-associated and non-disease-associated SNPs in 22 human disease genes. (genomeweb.com)
  • Genetic complementation studies indicate that the Drosophila RAD6 homolog can functionally substitute for the S. cerevisiae RAD6 gene in its DNA-repair and UV-mutagenesis functions but cannot substitute in sporulation. (eur.nl)
  • Our findings expand the genotypic spectrum of congenital NAD deficiency disorders and further implicate mutation of additional genes involved in de novo NAD synthesis as potential causes of complex birth defects. (bepress.com)
  • Diagnosis can now also be verified by the finding of a mutation in the SEDL gene. (nature.com)
  • A single nucleotide mutation of the IspE gene participating in the MEP pathway for isoprenoid biosynthesis causes a green-revertible yellow leaf phenotype in rice. (chinaagrisci.com)
  • Synthetic biology is explored through CRISPR/Cas9-directed engineering of heterologous biosynthetic pathways in yeast. (cshl.edu)
  • The completed rice genome sequence has been used for the characterization of a large number of gene families involved in diverse processes and pathways. (biomedcentral.com)
  • cdc25+ functions as an inducer in the mitotic control of fission yeast. (wikidata.org)
  • RePub, Erasmus University Repository: DHR6, a Drosophila homolog of the yeast DNA repair gene RAD6. (eur.nl)
  • DHR6, a Drosophila homolog of the yeast DNA repair gene RAD6. (eur.nl)
  • Research in Drosophila and in yeast shows that the unique feature of H2A.Z does not reside in its histone fold but in its carboxy-terminal domain, termed M6, which is essential for the survival of that organism. (usherbrooke.ca)
  • Amino acids 98-108 in yeast H2A.Z M6 region correspond to the conserved amino acids in Drosophila H2A.Z residues that are essential for its viability. (usherbrooke.ca)
  • Combinations of classical and modern genetic approaches are emphasized, including the isolation and characterization of mutants, tetrad analysis, and complementation. (cshl.edu)
  • Gene disruption and tetrad analysis showed that yeast cells contain two separate myoinositol transporters. (rhea-db.org)
  • As a source of insight we systematically analyzed the yeast orthologs in this highly conserved metabolic pathway. (bioinf.org)
  • Moreover, Reverse Transcription-Polymerase Chain Reaction (RT-PCR) verified that the alternative splicing of these two genes was associated with m6A modification. (bvsalud.org)
  • It was found that the variant histone H2A.Z regulates gene transcription. (usherbrooke.ca)
  • I next attempted to identify targets of the H2A.Z C-terminal region that are important for its function in gene transcription. (usherbrooke.ca)
  • This result suggests that SRF6 was possibly a target of the H2A.Z C-terminal region in DNA repair and gene transcription. (usherbrooke.ca)
  • This finding supports the special function of H2A.Z in gene transcription. (usherbrooke.ca)
  • The unexpected presence of multiple forms of each HAP homolog in Arabidopsis compared with the single genes in yeast and vertebrates suggests that the HAP235 complex may play diverse roles in gene transcription in higher plants. (camregbase.org)
  • Identical copies of a and alpha information are present at distal loci (HMR and HML), but transcription of these copies is repressed by the action, in trans, of four unlinked genes called SIR (silent information regulator). (ox.ac.uk)
  • SIR control can act on other promoters when they are brought near the E sequence, and thus the SIR gene products act in some general manner to repress transcription. (ox.ac.uk)
  • Bi-allelic loss-of-function mutations in genes required for the de novo synthesis of NAD were previously identified in individuals with multiple congenital abnormalities affecting the heart, kidney, vertebrae, and limbs. (bepress.com)
  • Transcriptional analysis of ACBP-deficient parasites revealed differentially expressed genes involved in a wide range of biological processes such as lipid metabolism, posttranslational modification, and membrane biogenesis. (biomedcentral.com)
  • The correlation analysis between the RNA-seq and m6A-seq data detected that a total of 315 differentially methylated genes were predicted to be significantly differentially expressed at the transcriptome level. (bvsalud.org)
  • Many genes involved in chlorophyll biosynthesis and chloroplast development were differentially expressed in the OsDXR knock-out lines compared to the wild type. (chinaagrisci.com)
  • Here, we will focus on recent advances in the understanding of tauopathies and how baker's yeast has helped to elucidate disease-relevant mechanisms. (microbialcell.com)
  • Characterization of two genes required for the position-effect control of yeast mating-type genes. (ox.ac.uk)
  • Molecular genetic techniques, including yeast transformation, gene replacement by PCR, construction and analysis of gene fusions, and generation of mutations, are also emphasized. (cshl.edu)
  • To understand the molecular control of barley spike and spikelet formation, we are conducting research using known genes from model plants such as Arabidopsis and rice as guidance. (edu.au)
  • The ITR1 and ITR2 genes contained long open reading frames capable of encoding 584 and 612 amino acids with calculated relative molecular masses of 63,605 and 67,041, respectively. (rhea-db.org)
  • The challenge is to use a transcriptome-driven approach to identify the gene(s) and molecular mechanisms underlying the phenotypic descriptions in each case. (genomeinterpretation.org)
  • Here, we present an overview on common modifications as they occur in tau during AD, summarize their potential relevance with respect to disease mechanisms and refer to the native yeast enzyme orthologs capable to perform these modifications. (microbialcell.com)
  • Thus, NADSYN1 represents an additional gene required for NAD synthesis during embryogenesis, and NADSYN1 has bi-allelic missense variants that cause NAD deficiency-dependent malformations. (bepress.com)
  • The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. (thermofisher.com)
  • The xeroderma pigmentosum variant complementation group (XP-V) has normal unscheduled DNA synthesis after UV exposure. (medscape.com)
  • Analysis of can be extremely conserved throughout advancement as are many genes working upstream and downstream in the sterol synthesis pathway (11). (bioinf.org)
  • In maize, the HXK family is composed of nine genes, but only six of them (ZmHXK4-9) putatively encode catalytically active enzymes. (biomedcentral.com)
  • In future studies, we plan to verify genes directly related to PaWB and methylation-related enzymes in Paulownia to elucidate the pathogenic mechanism of PaWB caused by phytoplasma invasion. (bvsalud.org)
  • Three human being catalytic enzymes SC4MOL NSDHL and HSD17B7 and a gene with unknown function are orthologous to a organic of candida C4-sterol demethylation genes define the "ergosome" (fibroblasts (Fig. S3C). (bioinf.org)
  • Analyze full-length infectious clones to determine the genes or gene products involved in replication, systemic movements, and pathogenicity to understand the role of viral pathogen genes in disease development and to identify new targets in the pathogen genome and tools for disease management. (usda.gov)
  • Students will be immersed in yeast genomics and perform and interpret experiments using DNA arrays, colony arrays, whole genome sequencing, and multiplexed DNA barcode sequencing. (cshl.edu)
  • Because it's genome has been sequenced, its genetics are easily manipulated, and it is easy to maintain in the lab, this species of yeast has been an invaluable resource in the understanding of fundamental cellular processes such as cell division and cell death. (jove.com)
  • The Rare Genomes Project (RGP) is a direct-to-participant research study on the utility of genome sequencing for rare disease diagnosis and gene discovery. (genomeinterpretation.org)
  • In contrast, a disruption of the AtKCR2 gene had no obvious phenotypic effect. (unl.edu)
  • Finally, disruption of the plastidial 2-C-methyl-derythritol-4-phosphate pathway resulted in defects in chloroplast development and the RNA editing of chloroplast genes. (chinaagrisci.com)
  • This strongly suggests that CHA1 is the structural gene for the yeast catabolic serine (threonine) dehydratase. (unipr.it)
  • We have determined the DNA sequence of two fragments which complement mutations in the SIR2 and SIR3 genes and show that these contain the structural genes by mapping the cloned sequences onto the yeast chromosome. (ox.ac.uk)
  • The objective in this challenge is to predict a patient's clinical phenotype and the causal variant(s) based on their gene panel sequences. (genomeinterpretation.org)
  • Repression by SIR also requires, in cis, DNA sequences called E which are found to the left of HML and HMR (but not MAT) and are greater than 1 kb from the mating-type gene promoters. (ox.ac.uk)
  • The SIR2 and SIR3 coding sequences were identified by constructing gene disruptions and using these mutations to replace the normal chromosomal copies. (ox.ac.uk)
  • Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. (wikipedia.org)
  • Both gene products show significant sequence homology with a superfamily of sugar transporters, including human HepG2 hepatoma/erythrocyte glucose transporter and Escherichia coli xylose transporter. (rhea-db.org)
  • The mating type of haploid yeast (a or alpha) is determined by information present at the MAT locus. (ox.ac.uk)
  • The importance of peroxisomes for human life is highlighted by severe inherited diseases which are caused by defects of peroxins, encoded by PEX genes. (tcdb.org)
  • Therefore, Zcf29p regulates stress response probably through its control of other genes not tested in our study. (ncl.edu.tw)
  • In this study, we identified OsDXR , a gene encoding a reductoisomerase that positively regulates chlorophyll biosynthesis and chloroplast development in rice. (chinaagrisci.com)
  • Eleven candidate reference genes were identified from the transcriptome data. (mpob.gov.my)
  • An autophagy-related gene Atg8 was cloned for the first time from wild emmer wheat, named as TdAtg8, and its role on autophagy under abiotic stress conditions was investigated. (sabanciuniv.edu)
  • Furthermore, some PfCaMs/CMLs might be involved in plants' reaction to phytoplasma infection and exogenous calcium therapy, indicating these genes may play a role in abiotic as well as biotic stress responses. (bvsalud.org)
  • 2005 ). The two AAA (ATPase associated with various cellular activities) peroxins, Pex1p and Pex6p, are the causal genes for CG (complementation group) 1 and CG4 PBDs respectively. (tcdb.org)
  • In yeast knockouts, supplanting human ARV1 through plasmid transfection rescues cells from death. (wikipedia.org)
  • Cell complementation analysis of cultured cells from patients with xeroderma pigmentosum demonstrated that xeroderma pigmentosum was genetically heterogeneous for the ability to repair UV-induced thymine dimers. (medscape.com)
  • Yeast cells use an anisotropic secretory apparatus for polarized growth at a selected bud site. (sdbonline.org)
  • Thus, the exocyst complex in yeast may provide a model for the directed membrane traffic of developing cells in higher organisms (Murthy, 2004 and references therein). (sdbonline.org)
  • The SBDS gene may not be required for neutrophil maturation but may act to maintain survival of granulocyte precursor cells. (medscape.com)
  • Previous studies have identified four putative DGAT2-encoding genes in H. lacustris , and only HpDGAT2D allowed the recovery of TAG biosynthesis, but the engineering potential of HpDGAT2s in TAG biosynthesis remains ambiguous. (researchsquare.com)
  • Five putative DGAT2 genes ( HpDGAT2A , HpDGAT2B , HpDGAT2C , HpDGAT2D , and HpDGAT2E ) were identified in H. lacustris . (researchsquare.com)
  • Lectures on fundamental aspects of yeast genetics will be presented along with seminars given by prominent experts in the field on topics of current interest. (cshl.edu)
  • Although less prevalent than its relative Candida albicans, the yeast Candida glabrata is a successful pathogen of humans which causes life-threatening candidiasis. (leibniz-hki.de)
  • Furthermore, we have mapped the chromosomal position of the CHA1 gene to less than 0.5 kb centromere proximal to HML on the left arm of chromosome III. (unipr.it)
  • In 90% of the cases, Shwachman-Diamond syndrome is associated with mutations in the Shwachman-Bodian-Diamond syndrome ( SBDS ) gene located on chromosome 7. (medscape.com)
  • Also, Shwachman-Diamond syndrome has been associated with mutations in the SBDS gene, located on chromosome 7. (medscape.com)
  • The function of the human gene has not yet been determined. (thermofisher.com)
  • 19- Zhou B, Gitschier J. hCTRl: a human gene for copper uptake identified by complementation in yeast. (9lib.net)
  • Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. (yeastgenome.org)
  • The Ran GTPase cycle is required for yeast nuclear pore complex assembly. (tamu.edu)
  • Treating cultured wild-type cotton ovules with exogenous phytohormones showed that individual genes can be induced by different agents. (singerinstruments.com)
  • The MADS -box gene family is important in inflorescence development in many plants, most notably in the ABC model of floral organ development in Arabidopsis. (edu.au)
  • homologous genes have been discovered in several species ranging from yeast to mammals. (medscape.com)