BRCA1 ProteinGenes, BRCA1BRCA2 ProteinGenes, BRCA2Breast NeoplasmsGerm-Line MutationOvarian NeoplasmsHeterozygoteRad51 RecombinaseMutationGenetic TestingNeoplasm ProteinsGenetic Predisposition to DiseaseDNA RepairDNA DamageTranscription FactorsJewsFounder EffectBreast Neoplasms, MaleTumor Cells, CulturedNeoplastic Syndromes, HereditaryDNA Mutational AnalysisGenetic CounselingSalpingectomyTumor Suppressor ProteinsHomologous RecombinationPedigree