Different strains of mice may have different numbers of endogenous retroviruses, and new viruses may arise as the result of recombination of endogenous sequences. (wikipedia.org)
1939 International Committee on Standardized Nomenclature for Mice begins, bringing order to the naming of mice and their genes. (jax.org)
Western blot hybridization studies showed that T2CA downregulates the expression of total gal 3 proteins and extended the survival of AKR/J mice injected with Ehrlich ascites tumor cells in the Kepler-Meier survival curve analysis. (arjournals.org)
Retroviruses3
The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts. (wikipedia.org)
The murine leukemia viruses are group/type VI retroviruses belonging to the gammaretroviral genus of the Retroviridae family. (wikipedia.org)
As Type C retroviruses, replicating murine leukemia viruses produce a virion containing a spherical nucleocapsid (the viral genome in complex with viral proteins) surrounded by a lipid bilayer derived from the host cell membrane. (wikipedia.org)
Tumor2
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. (academicinfluence.com)
Deletion of galectin-3 in the host attenuates metastasis of murine melanoma by modulating tumor adhesion and NK cell activity. (arjournals.org)
BALB1
Several commonly used laboratory mouse strains such as BALB/c, SJL, AKR, CBA, C3H and A do not express the NK1.1 antigen. (thermofisher.com)
Proteins5
The encoded proteins are trafficked to the plasma membrane, where they assemble into progeny virus particles. (wikipedia.org)
Retroviral proteins, often glycosylated, coded by the envelope (env) gene. (lookformedical.com)
The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. (lookformedical.com)
Effect of host strain and H-2 type on spontaneous regression of murine leukemia. (jax.org)
Antigen2
Antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent, usually a virus. (lookformedical.com)
Here, we use a BCR light chain neoepitope defined by a characteristic point mutation (IGLV3-21R110) for selective targeting of a poor-risk subset of chronic lymphocytic leukemia (CLL) with chimeric antigen receptor (CAR) T cells. (bvsalud.org)
Receptor2
NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand. (thermofisher.com)
Recognition of a virus-encoded ligand by a natural killer cell activation receptor. (arjournals.org)
Type1
Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. (thermofisher.com)
Mouse1
Among the latter MLVs are amphotropic viruses (Gr. amphos, "both") that can infect both mouse cells and cells of other animal species. (wikipedia.org)
Protein4
The env genes contain a cis-acting RNA target sequence for the rev protein (= GENE PRODUCTS, REV ), termed the rev-responsive element (RRE). (lookformedical.com)
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. (lookformedical.com)
Layers of protein which surround the capsid in animal viruses with tubular nucleocapsids. (lookformedical.com)
Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. (lookformedical.com)
Cells1
We develop murine and humanized CAR constructs expressed in T cells from healthy donors and CLL patients that eradicate IGLV3-21R110 expressing cell lines and primary CLL cells, but neither cells expressing the non-pathogenic IGLV3-21G110 light chain nor polyclonal healthy B cells. (bvsalud.org)
Exogenous and endogenous murine1
The genomes of exogenous and endogenous murine leukemia viruses have been fully sequenced. (wikipedia.org)
Endogenous retroviruses2
Different strains of mice may have different numbers of endogenous retroviruses, and new viruses may arise as the result of recombination of endogenous sequences. (wikipedia.org)
Radiation-induced murine leukemias and endogenous retroviruses: the time course of viral expression. (microbiologyresearch.org)
Mammary1
different populations of wild mice (mus musculus domesticus) in los angeles and ventura counties were observed over their lifespan in captivity for expression of infectious murine leukemia virus (mulv) and murine mammary tumor virus (mmtv) and for the occurrence of cancer and other diseases. (liverpool.ac.uk)
Lymphocyte1
8. Flow cytometry in the differential diagnosis of lymphocyte-rich thymoma from precursor T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. (nih.gov)
Strains3
We were doing work on enteric viruses in water and sewage and, at that time, I was also collecting fecal specimens from Albert Sabin's polio vaccine experiments to determine what quantities of Poliovirus were in feces, and we were using his vaccine strains in his volunteers as some indication of what you could find in raw feces. (nih.gov)
tcrg gene polymorphism was investigated by southern blot analysis on a panel of laboratory and wild mouse strains using a set of probes which identify all known tcrg-v and -c genes. (liverpool.ac.uk)
Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. (nih.gov)
Viral2
As Type C retroviruses, replicating murine leukemia viruses produce a virion containing a spherical nucleocapsid (the viral genome in complex with viral proteins) surrounded by a lipid bilayer derived from the host cell membrane. (wikipedia.org)
Different serotypes of B-tropic murine leukemia viruses and association with endogenous ecotropic viral loci. (microbiologyresearch.org)
Recombination1
Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences. (nih.gov)
Acute4
4. The IL-6 gene expression by leukemic cells from acute lymphoblastic leukemia common and T type and modulation of IL-6 production by TNF. (nih.gov)
5. Characterization of a novel malignant B cell line with t(14;18) and t(4;11) established from a patient with acute monoblastic leukemia. (nih.gov)
9. High-resolution genomic profiling of pediatric lymphoblastic lymphomas reveals subtle differences with pediatric acute lymphoblastic leukemias in the B-lineage. (nih.gov)
The envelope gene plays an essential role in initiating erythroleukemia ( LEUKEMIA, ERYTHROBLASTIC, ACUTE ), manifested by splenic foci, SPLENOMEGALY , and POLYCYTHEMIA . (nih.gov)
Progeny virus3
The encoded proteins are trafficked to the plasma membrane, where they assemble into progeny virus particles. (wikipedia.org)
In this case, the progeny virus was produced in the activated form and multiple-cycle replication occurred successively. (nih.gov)
The progeny virus, however, remained inactive, and the replication was limited to a single cycle, which resulted in the limited lung lesion. (nih.gov)
Erythroleukemia1
Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene. (microbiologyresearch.org)
Replication1
When trypsin treatment was made which cleaved F into F(1) and F(2) subunits, the virus became activated so that it could initiate replication in the bronchial epithelium of the lung. (nih.gov)
Expression5
It is also nuclear, but is neither as polymorphic nor as ubiquitous as the pp53 - found only in SV-transformed cells, It appears to be a cellular protein whose expression is related to expression of A gene, The proteins secreted by normal and transformed proteins reported previously by Hynes lab were reviewed. (nih.gov)
1. Alpha 4 beta 7 integrin expression is associated with the leukemic evolution of human and murine T-cell lymphoblastic lymphomas. (nih.gov)
17. Development-dependent expression of cyclin D3 in precursor T-cell lymphoblastic leukemia/lymphoma. (nih.gov)
GBMs with loss of MSH2 and MSH6 expression displayed giant and multinucleated bizarre cells, along with mutations in ARID1A, TP53, ATM, and NF1 genes. (bvsalud.org)
The integrated analyses of The Cancer Genome Atlas (TCGA) datasets and bioinformatics methods were adopted to discover gene expression, gene coexpression, and overall survival in patients with breast cancer. (bvsalud.org)
Radiation3
She went back home and they said, after that, that that radiation virus turned out to be a virus. (nih.gov)
Serological characterization of C-type retroviruses endogenous to the C57BL/6 mouse and isolated in tumours induced by radiation leukaemia virus (RadLV-Rs). (microbiologyresearch.org)
Progression1
6. In vivo phenotypic characteristics of AKR T-cell lymphomas with different leukemic potential: possible role of alpha 4 beta 7 integrin in the progression towards the leukemic phenotype. (nih.gov)
Laboratory1
He was at the National Institute of Allergy and Infectious Diseases and had a Branch, or a Laboratory, consisting of a number of well known investigators, amongst which was Wally Rowe and, in his lab, Janet Hartley, who were pretty well known for work in some of the murine viruses. (nih.gov)
Cancer1
The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts. (wikipedia.org)