Loading...
  • genome
  • Lemaux, Peggy 2006-09-27 00:00:00 Transposable elements have certain advantages over other approaches for identifying and determining gene function in large genome cereals. (deepdyve.com)
  • BLAST searches using a gene prediction program revealed that 86% of TNP flanking sequences matched either known or putative genes, indicating preferential Ds insertion into genic regions, critical in large genome species. (deepdyve.com)
  • Observed remobilization frequencies of primary, secondary, tertiary, and quaternary TNPs, coupled with the tendency for localized Ds transposition, validates a saturation mutagenesis approach using Ds to tag and characterize genes linked to Ds in large genome cereals like barley and wheat. (deepdyve.com)
  • This is strikingly consistent with the known composition of the genome of M. genitalium , which contains approximately 470 genes, not all of which are essential. (nap.edu)
  • traits
  • With an increase in the number of candidate genes for important traits in livestock, effective strategies for incorporating such genes into selection programmes are increasingly important. (unl.edu)
  • sequences
  • Sometimes, however, 16S rRNA or other marker genes in environmental samples exhibit "microdiversity" at this or more stringent levels, with an overabundance of closely related sequences that could be interpreted as resulting from speciation-like ecological and genetic processes ( 2 ⇓ - 4 ). (pnas.org)
  • increase
  • Conclusive evidence that this effect is caused by proximity to the centromere was demonstrated by Sturtevant and Beadle (1936) , who found that crossover frequencies in the proximal euchromatin increase when this region is moved away from the centromere by inversion. (g3journal.org)
  • individual
  • Any genes that could wind up in the same individual through sexual reproduction are in the same gene pool. (berkeley.edu)
  • Unknown forces do, however, appear to play a role in Helicobacter pylori , and some individual genes in all groups fail to conform to the null model. (pnas.org)
  • Using time-lapse microscopy, we found that Crz1 exhibited short bursts of nuclear localization (~2 minutes) that occurred stochastically in individual cells and propagated to the expression of downstream genes. (pubmedcentralcanada.ca)
  • The selective advantage, s , of a beneficial mutation is typically defined for haploids as follows: if each wild-type individual has on average W offspring per generation, each mutant individual has on average W (1+ s ) offspring. (royalsocietypublishing.org)
  • duration
  • Breakpoint -- a minimum inhibitory concentration (as determined by the Veterinary Antimicrobial Susceptibility Testing subcommittee of the Clinical and Laboratory Standards Institute) selected to predict clinical outcome for a specific veterinary pathogen, in a specific disease, in a specific species, given a specific regimen (dose, route, duration, and frequency) and used to define bacteria isolated from animals as susceptible, intermediate, or resistant. (avma.org)
  • causes
  • Searching South Australia's Barossa Valley for carriers of the gene that causes genetic high cholesterol is the focus of new Griffith University research. (edu.au)
  • A significant number from the Silesian area had a special gene mutation of FH called FH Morocco which causes very high cholesterol levels and can lead to premature heart attack. (edu.au)
  • next generation
  • To investigate the intrinsic mutation frequency and substitution bias of SHMs at the amino acid level, we analyzed functional human antibody repertoires and developed mGSSP (method for gene-specific substitution profile), a method to construct amino acid substitution profiles from next-generation sequencing-determined B cell transcripts. (frontiersin.org)
  • genotypes
  • However, through segregation analysis, probable genotypes can be assigned to individuals that themselves were not tested, using known genotypes on relatives and a starting (presumed) gene frequency. (unl.edu)
  • The value of these probable genotypes in estimation of gene frequency was considered. (unl.edu)
  • Different
  • To examine this phenomenon molecularly, we developed an assay that measures meiotic crossovers and noncrossover gene conversions between allelic transgenes inserted into different genomic positions. (g3journal.org)
  • species
  • Extralabel use in food animals necessitates an extralabel withdrawal interval to be assigned by the attending veterinarian, on the basis of information on the species, dose, route, and frequency of treatment, in conjunction with available scientific pharmacokinetic data. (avma.org)
  • known
  • But it is not known in general how the expression levels of target genes are coordinated, allowing them to be regulated together, despite diverse promoter architectures 3 . (pubmedcentralcanada.ca)
  • Common
  • We think it may be even more common than type 1 diabetes and it's all due to a single gene mutation affecting cholesterol. (edu.au)
  • found
  • Using an analytic model, we found that this frequency modulation (FM) of bursts ensures proportional expression of multiple target genes across a wide dynamic range of expression levels, independent of promoter characteristics. (pubmedcentralcanada.ca)
  • general
  • These results suggest that FM regulation of localization bursts may be a general control strategy utilized by the cell to coordinate multi-gene responses to external signals. (pubmedcentralcanada.ca)
  • There was general agreement among panelists and discussants that approximately 250 to 450 genes compose the set of minimal essential genes. (nap.edu)
  • Generally
  • Via a combination of simulations and analyses of core and phylogenetic marker genes, we show that patterns of diversity for the genera Escherichia , Neisseria , and Borrelia are generally indistinguishable from patterns arising under a null model. (pnas.org)
  • carriers
  • Led by Professor Ian Hamilton-Craig from the Griffith University School of Medicine, and working with local doctors in the region, the Barossa Family Heart Study aims to identify carriers of the familial hypercholesterolemia (FH) gene in a bid to provide them with treatment and reduce their risk of premature heart disease. (edu.au)