Reactive Oxygen SpeciesOxygenOxidative StressHydrogen PeroxideAntioxidantsNADPH OxidaseFree Radical ScavengersMitochondriaSuperoxide DismutaseOxygen ConsumptionOxidation-ReductionCatalaseSuperoxidesAcetylcysteineOxidantsApoptosisCells, CulturedMembrane Potential, MitochondrialGlutathioneSignal TransductionLipid PeroxidationOnium CompoundsReactive Nitrogen SpeciesXanthine OxidaseSinglet OxygenCell SurvivalCyclic N-OxidesCell DeathFree RadicalsNitric OxideHydroxyl RadicalEnzyme ActivationCell Line, TumorCell LineEnzyme InhibitorsDose-Response Relationship, DrugMice, Inbred C57BLRats, Sprague-DawleyDNA DamageGlutathione PeroxidaseTime FactorsRotenoneBlotting, WesternLuminescent MeasurementsAscorbic AcidModels, BiologicalRespiratory Burst1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium SaltAcetophenonesMice, KnockoutCytochromes cMitochondrial ProteinsXanthineVitamin K 3Mitochondria, HeartNeutrophilsCaspase 3AnoxiaOxygen Inhalation TherapyElectron Transport Complex IEndothelium, VascularMetalloporphyrinsCaspasesRNA, MessengerCell HypoxiaRats, WistarPeroxiredoxinsPhosphorylationElectron TransportDeoxyguanosineDisease Models, AnimalProtein CarbonylationSpin LabelsCell RespirationUp-RegulationCalciumNF-kappa BNADH, NADPH OxidoreductasesMalondialdehydeParaquatNF-E2-Related Factor 2Gene Expression RegulationDNA FragmentationMutationp38 Mitogen-Activated Protein KinasesCytoprotectionrac1 GTP-Binding ProteinTioproninRNA, Small InterferingThioredoxinstert-ButylhydroperoxideEndothelial CellsCell ProliferationUncoupling AgentsThenoyltrifluoroacetoneReverse Transcriptase Polymerase Chain ReactionHeme Oxygenase-1DeferoxaminePlant ExtractsGlutathione Disulfide