The current "trinity" of gasotransmitters, nitric oxide, carbon monoxide, and hydrogen sulfide, have ironically been discarded as useless toxic gases throughout history. (wikipedia.org)
Nitric oxide and hydrogen sulfide are highly reactive with numerous molecular targets, whereas carbon monoxide is relatively stable and metabolically inert predominately limited to interacting with ferrous ion complexes within mammalian organisms. (wikipedia.org)
Relative to carbon monoxide and hydrogen sulfide, NO is exceptional due to the fact it is a radical gas. (wikipedia.org)
I proposed the establishment of the 'gasotransmitter' concept and framework firstly in 2002 to characterize and clarify a class of endogenous gas molecules, including nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H 2 S), that function as signaling molecules to direct various molecular and cellular events. (rsc.org)
Nitric oxide2
NO is biosynthesized endogenously from L-arginine by various nitric oxide synthase (NOS) enzymes. (wikipedia.org)
For the human body to generate NO through the nitrate-nitrite-nitric oxide pathway, the reduction of nitrate to nitrite occurs in the mouth by the oral microbiome. (wikipedia.org)
Induce1
The goal of this proposal is to investigate a novel preservation method utilizing hydrogen sulfide (H2S) to induce a protective state of hibernation against I/R injury. (gotomydoctor.com)
Production1
Canadian production of hydrogen sulphide by manufacturers of pigments and dye colours amounted to 10.7 tonnes in 1974. (canada.ca)
Function1
Oxidation of hydrogen sulphide is also a function of temperature, pH and ionic strength. (canada.ca)
State1
the - 2 reduction state is known as sulphide. (canada.ca)
Plants2
Hydrogen sulfide (H 2 S) effectively alleviates heavy metal toxicity in plants and reduces oxidative stress in mammals. (biomedcentral.com)
Recent studies revealed that exogenous gaseous signal molecule hydrogen sulfide (H 2 S) improve Cd tolerance in plants by reducing oxidative damage. (biomedcentral.com)
Studies1
This ongoing area of research has led to further investigations into the 1,5-hydrogen atom transfer process and in particular, studies into the effectiveness of deuterium as a protecting group for C-H bonds in radical and carbene chemistry. (exeter.ac.uk)
Phenols1
We analyzed the vector directionalities of the lone pairs of the nitrogen common to these molecules, and the acidic hydrogen of phenols (in aminoindanes, aminotetralins, apomorphines, p-phenol-piperazines, octahydrobenzo(g)quinolines, octahydrobenzo(f)quinolines, and benzazepines) or of nitrogen (in ergoline-type compounds and related structures). (nih.gov)
Nitric oxide and hydrogen sulfide are highly reactive with numerous molecular targets, whereas carbon monoxide is relatively stable and metabolically inert predominately limited to interacting with ferrous ion complexes within mammalian organisms. (wikipedia.org)
Minerals can 49 serve as redox partners for OM through direct electron transfer or by generating reactive oxygen 50 species, which then oxidize OM. (docslib.org)
Enzymes3
NO is biosynthesized endogenously from L-arginine by various nitric oxide synthase (NOS) enzymes. (wikipedia.org)
These data confirm a key role for the H 2 S-generating enzymes Cbs and Cth in pulmonary vascular development and homeostasis and in lung alveolarization. (elsevierpure.com)
[ 1 ] However, the expression of H 2 S-generating enzymes and the endogenous production of H 2 S have recently been identified in male and female reproductive systems in various mammalian species. (medscape.com)
Role1
The proerectile role of endogenously produced H 2 S was later confirmed by a study by same group in rabbit cavernosum, [ 45 ] where they found that NaHS relaxes the strips from rabbit corpus cavernosum, while both CBS and CSE inhibitors markedly increase the contraction induced by electrical-field stimulation. (medscape.com)