Loading...
  • evidence
  • Not quite, according to scientists from the Woods Hole Marine Biological Laboratory (MBL), who have uncovered evidence of "massive" horizontal gene transfer in the animal known as the bdelloid rotifer. (scienceagogo.com)
  • A. C. Martiny, M. L. Coleman, and S. W. Chisholm, "Phosphate acquisition genes in Prochlorococcus ecotypes: evidence for genome-wide adaptation," Proceedings of the National Academy of Sciences of the United States of America , vol. 103, no. 33, pp. 12552-12557, 2006. (hindawi.com)
  • In fact, due to increasing evidence suggesting the importance of the phenomenon in organisms that cause disease, molecular biologists such as Peter Gogarten at the University of Connecticut have described horizontal gene transfer as "a new paradigm for biology. (mpkb.org)
  • Genes carrying PKS and NRPS domains were identified in clusters on the CDC and evidence supporting the origin of the CDC through horizontal transfer from an unrelated fungus was found. (7thspace.com)
  • Conclusions: We provide evidence supporting the hypothesis that the CDC in A. arborescens was acquired through horizontal transfer, likely from an unrelated fungus. (7thspace.com)
  • chromosome
  • Or it may simply not be selected against as efficiently as the more deleterious DNA insertions into the central, gene-rich regions of the chromosome," she concluded. (scienceagogo.com)
  • arborescens is a major pathogen of tomato, with its virulence determined by the presence of a conditionally dispensable chromosome (CDC) carrying host-specific toxin genes. (7thspace.com)
  • Differences in nucleotide usage were found between CDC genes and those on the essential chromosome (EC), including GC3-content, codon usage bias, and repeat region load. (7thspace.com)
  • functionally
  • The team has revealed the likely mechanism by which this gene ended up being expressed in a functionally important and tissue-specific way. (eurekalert.org)
  • Predicted genes were functionally annotated through BLAST. (7thspace.com)
  • bacterium
  • 1 The Wolbachia bacterium is able to do this extraordinary feat by targeting the cells of reproductive organs so that the transferred DNA is literally inherited in the host. (icr.org)
  • In a new discovery that increases our understanding of gene transfer, a research team centered at University of Tsukuba has studied a gene in marine invertebrates called ascidians originally came from a common bacterium. (eurekalert.org)
  • Just to be precise, the putative gene cluster which could be responsible for the synthesis of the antifungal molecule, consisting of 13 different genes, is in the genome of the symbiont bacterium, and the possible HGT is therefore HGT between bacterial strains. (uncommondescent.com)
  • genome-wide
  • Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli , according to a study. (the-scientist.com)
  • vertically
  • A detailed functional classification confirms that genes related to protein translation are vertically inherited, whereas interestingly, transport and binding proteins are strongly enriched among HGT genes. (springer.com)
  • protein
  • In mammals, genes are quite complex, and on average only about 10% of the entire gene sequence actually codes for protein, the rest contains a large diversity of regulatory sequences that determine how the gene is to function and its various types of products. (icr.org)
  • This gene encodes a protein that helps form an external protective coating, the loss of which leads to a lack of cellulose production and has adverse effects on these organisms. (eurekalert.org)
  • Studies performed with Escherichia coli W3110 genome clearly show that HGT proteins have fewer interactions when compared to those predicted as vertical inherited, an indication that the number of protein partners imposes limitations to horizontal transfer. (springer.com)
  • divergent
  • Divergent tetranucleotide frequency and codon usage showed that the gene cluster of T. carboxydivorans that encodes a [Ni,Fe]-CODH and an energy-converting hydrogenase is dissimilar to its whole genome but is similar to the genome of the phylogenetically distant Firmicute, Carboxydothermus hydrogenoformans . (frontiersin.org)
  • donors
  • Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. (the-scientist.com)
  • Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body. (the-scientist.com)
  • Conjugation
  • Conjugation occurred in all concentrations, but efficiencies of transfer were consistently low in 0 MIC and 1 MIC, with increased activity both above and below 1 MIC. (k-state.edu)
  • found
  • However, we also observed that very few of these transferred genes were found to be expressed (turned on). (icr.org)
  • Third, no mechanism of HGT for any of the hundreds of alleged 'foreign genes' they found was either discovered or even suggested. (icr.org)
  • newly
  • These findings provide interesting insight into one way in which the conditions in the new host can facilitate expression of a newly transferred gene and its integration into the host's functions, reducing the improbability that a randomly inserted foreign gene could actually be beneficial. (eurekalert.org)
  • foreign
  • This is actually one of the few clearly documented cases of horizontal gene transfer showing that a specific type of parasite-host relationship is the mechanism for the foreign DNA importation to occur and be heritable. (icr.org)
  • Clearly, the genes are not foreign at all, but designed to function as key parts of essential biologically complex systems. (icr.org)
  • In fact, they admitted their claim that the gene was foreign-or where it originated from-was purely hypothetical, when they stated that 'absolute certainty in the assignment of most HGT is unachievable. (icr.org)
  • It is quite amazing that bdelloids are able to recruit foreign genes, which were acquired from remarkably diverse sources, to function in the new host," says MBL's Irina Arkhipova. (scienceagogo.com)
  • nature
  • This is due to the fact that the only cases where such gene transfer occurs in nature typically involves a clear host-parasite relationship. (icr.org)