• The subcellular localization and stage-specific expression of several putative lncRNAs were validated using RNA fluorescence in situ hybridization (RNA-FISH). (biorxiv.org)
  • In situ hybridization of a radioactive RNA probe on resin-embedded legume root-nodule sections: a tool for observing gene expression in the rhizosphere? (agronomy-journal.org)
  • In this work we performed in situ hybridization of a carbonic anhydrase RNA 35 S-labeled probe on nodule sections previously embedded in a methacrylate resin. (agronomy-journal.org)
  • Use of histopathology, PCR and in situ hybridization methods to detect the parasite Mikrocytos sp. (agronomy-journal.org)
  • However, here using reverse transcription-PCR and in situ hybridization we show that mRNA encoding the ρ1 subunit is highly expressed in brainstem neurons. (jneurosci.org)
  • What is in situ hybridization and what are the recent advancements with this indispensable technique? (enzolifesciences.com)
  • Bioinformatics analyses, the dual-luciferase reporter system, fluorescence in situ hybridization (FISH) and miRNA/mRNA high-throughput sequencing were used to identify circ-EPB41 and its downstream target. (biomedcentral.com)
  • We studied by in situ hybridization and RNA blots the pattern of 9E3 mRNA distribution in the wings of normal, wounded, and RSV-infected newly hatched chicks. (silverchair.com)
  • We here present a micrometer-scale implementation of fluorescence in situ hybridization that we term μFISH. (springer.com)
  • It relies on the sequence-specific hybridization of probes to their complementary targets in individual cells, followed by direct or indirect detection of the labelled probe. (springer.com)
  • A key milestone in ISH-based techniques was fluorescence in situ hybridization (FISH) (Bauman et al. (springer.com)
  • See the in situ hybridization pattern in Kohara NextDB . (nih.gov)
  • We have used in situ hybridization and immunocytochemistry to compare the nuclear localization of a specific nascent pre-mRNA and the essential non-snRNP splicing factor SC-35. (northwestern.edu)
  • Nascent c-fos transcripts were detected in serum-induced mouse fibroblasts by in situ hybridization with genomic c-fos probes. (northwestern.edu)
  • Fluorescence in situ hybridization fish is a molecular biology technique that can be used to detect microorganisms known to biodegrade contaminants. (web.app)
  • Fluorescence in situ hybridization fish assays employ fluorescently labeled probes to interrogate the bcr and abl1 loci. (web.app)
  • Fluorescence in situ hybridization fish is an effective technique that enables direct visualization of genetic alterations in the cell. (web.app)
  • Fluorescence in situ hybridization fish is a cytogenic technique used for the detection and localization of rna sequences within tissues or cells 116. (web.app)
  • Fluorescent in situ hybridization fish is a molecular cytogenetic technique that uses fluorescent probes that bind to only those parts of the chromosome with a. (web.app)
  • Fluorescent in situ hybridization fish assay grenoble ecobiz. (web.app)
  • Fluorescence in situ hybridization fish is a technique that uses fluorescent probes which bind to special sites of the chromosome with a high degree of sequence complementarity to the probes. (web.app)
  • Fluorescence in situ hybridization fish preparation of fish probe recommended filter set fish is a technique used to identify and localize the presence or absence of specific dna sequences on cells and tissues. (web.app)
  • It has emerged as a powerful cytogenetic method for the analysis of cells and tissues on the transcriptome and genome level with more than 6 publications in the literature per day since the late 1990s fig. Fluorescence in situ hybridization fact sheet itrc. (web.app)
  • Why is fluorescence in situ hybridization relevant. (web.app)
  • Fluorescence in situ hybridization fish is a cytogenetic technique used to detect the presence or absence and location of specific gene sequences. (web.app)
  • Review applications of fluorescence in situ hybridization fish in. (web.app)
  • The application of fluorescence in situ hybridization fish to cll has substantially enhanced our ability to detect chromosomal aberrations. (web.app)
  • Fluorescence in situ hybridization fish preparation of fish probe recommended filter set. (web.app)
  • The development of molecular hybridization techniques such as fluorescence in situ hybridization fish has had a major impact on efforts to detect and characterize the genetic changes that give. (web.app)
  • Fluorescence in situ hybridization fish is a molecular cytogenetic technique that uses. (web.app)
  • Pdf the development of molecular hybridization techniques such as fluorescence in situ hybridization fish has had a major impact on. (web.app)
  • Procedures for fluorescent in situ hybridization materials supplied directly labeled probe in hybridization buffer green or orange depending on the kit type storage instruction store at 20c in the dark. (web.app)
  • Serial biopsy shaves used for gene expression were also processed for in-situ hybridization (ISH) for a subset of genes. (escholarship.org)
  • This gene has no protein-coding homolog in any other genome but its presence is supported by evidence from expression and hybridization data. (ubc.ca)
  • This GLABR gene was further characterized by a conditional knockout experiment as well as an in situ hybridization on sectioned epithelial cells in order to better determine its function. (ubc.ca)
  • This is the first study describing the production and distribution of ETS-1 and ETS-2 mRNAs and proteins using in situ hybridization and immunohistochemistry in murine ocular tissue sections of normal control eyes and tumoral eyes from mice of the same age. (molvis.org)
  • RNA pull down assay, luciferase reporter assay and fluorescence in situ hybridization were applied to verify the interaction between BCRC-3 and microRNAs. (biomedcentral.com)
  • NEW YORK ─ Bio-Techne and Leica Biosystems said Tuesday that they have received the CE mark for Bio-Techne's RNAscope In Situ Hybridization Detection Kit for automation on the Leica Biosystems Bond-III staining platform. (genomeweb.com)
  • The life sciences firm's RNAscope In Situ Hybridization Detection Kit and probes identify RNA expression patterns and localization at the single-cell level with spatial and morphologic context. (genomeweb.com)
  • Individual expression patterns are extraordinarily diverse, but by supplementing qualitative in situ hybridization data with quantitative microarray time-course data using a hybrid clustering strategy, we identify groups of genes with similar expression. (biomedcentral.com)
  • RNA in situ hybridization has the potential to reveal both spatial and temporal aspects of gene expression during development. (biomedcentral.com)
  • However, RNA in situ hybridization is not quantitative [ 7 ]. (biomedcentral.com)
  • Minogue AL, Arur S*. In Situ Hybridization for Detecting Mature MicroRNAs In Vivo at Single-Cell Resolution. (mdanderson.org)
  • Localization of HuC (ELAVL3) to chromosome 19p13.2 by fluorescence in situ hybridization utilizing a novel tyramide labeling technique. (nih.gov)
  • NEW YORK, NY, Sept. 26, 2022 (GLOBE NEWSWIRE) -- Enzo Biochem, Inc. (NYSE: ENZ) ("Enzo" or the "Company"), a leading biosciences and diagnostics company, today announced the launch of the AMPIVIEW™ line, a breakthrough RNA gene expression platform powered by Enzo's LoopRNA™ in situ hybridization technology. (enzo.com)
  • HPV testing is part of Enzo's focus on women's health and oncology and leverages the Company's long history in HPV detection while complementing the existing offering of Enzo's POLYVIEW® immunohistochemistry ("IHC") and PATHO-GENE® in situ hybridization ("ISH") detection platforms, an enhanced diagnostic detection system used by pathologists in reading tissue biopsies. (enzo.com)
  • The study utilized immunochemistry, in situ hybridization (ISH), and gene rearrangement to confirm the disease and and performed a clinical follow up for each case. (biomedcentral.com)
  • A sensitive and specific fluorescence in situ hybridisation protocol was combined with protein immunostaining to show that both sense and antisense foci were frequent, specific to C9FTLD, and present in neurons of the frontal cortex, hippocampus and cerebellum. (nih.gov)
  • The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. (wikipedia.org)
  • STAU1 localization with the rough endoplasmic reticulum (RER) emphasizes its role in transporting mRNA to the site of translation. (wikipedia.org)
  • Once STAU1 is bound to the target mRNA, an interaction occurs between STAU1 and RNA helicase UPF1, which enhances its helicase activity and promotes SMD. (wikipedia.org)
  • Click on any transcript to open the specific mRNA page, to see the exact cDNA clone support and eventual SNPs and to get details on tissues, sequences, mRNA and protein annotations. (nih.gov)
  • This study demonstrates a direct link between specific nascent RNA transcripts and nuclear speckles that are enriched in pre-mRNA splicing factors. (northwestern.edu)
  • Furthermore, we found homogenous and recurrent iCNV profiles in the high-grade tumors of relapse patients and identified expression of gene SPP1 in the tumor stroma as a potential prognostic mRNA marker in pediatric brain tumor relapse patients. (kth.se)
  • To address the mechanism of isoform-specific mRNA localization, molecular chimeras were constructed by insertion of actin sequences between the Lac Z coding region and SV-40 3'UTR in a reporter plasmid. (umassmed.edu)
  • Since the blue-insoluble reaction product co-localized with the specific mRNAs expressed from each construct, it was used as a bioassay for mRNA localization. (umassmed.edu)
  • We propose that the mechanism of mRNA localization facilitates actin isoform sorting in the cytoplasm. (umassmed.edu)
  • In situ localization of HLA class I mRNA in human testis. (ox.ac.uk)
  • We have used a 0.35-kilobase (kb) antisense RNA probe complementary to the monomorphic regions of both classical and nonclassical HLA class I sequences to detect histocompatibility-class-I-antigen-specific mRNA in human testicular tissue. (ox.ac.uk)
  • Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. (wikipedia.org)
  • These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. (wikipedia.org)
  • Non-coding repeat expansions may cause disease by reducing the expression level of the gene they reside in, by producing toxic aggregates of repeat RNA termed RNA foci, or by producing toxic proteins generated by repeat-associated non-ATG translation. (nih.gov)
  • Nanos are RNA-binding proteins playing crucial roles in germ cell development and maintenance. (nature.com)
  • The Nanos proteins family regroups highly conserved RNA-binding proteins in higher eukaryotes implicated in germ cell development and maintenance. (nature.com)
  • They can detect everything from DNA and RNA to proteins and lipids, allowing researchers to investigate a vast array of cellular functions. (dadangoray.com)
  • Proteins: Fluorochrome can detect specific proteins in cells or tissues, allowing researchers to study their distribution and expression levels. (dadangoray.com)
  • The process of making proteins from genes is similar to that of a factory, where employees must follow a set of instructions that are both effective and precise. (azolifesciences.com)
  • The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. (nih.gov)
  • Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. (shengsci.com)
  • Methods: We designed and optimized assays to quantify 19 target genes, including previously reported set of tissue common rejection module (tCRM) genes. (escholarship.org)
  • This innovative design enables sensitive and specific detection of target genes in tissue or cell samples while preserving the morphology. (enzo.com)
  • Localization of 9E3/CEF-4 in avian tissues: expression is absent in Rous sarcoma virus-induced tumors but is stimulated by injury. (silverchair.com)
  • The abundant expression of 9E3 in normal tissues indicates that the product of this gene plays a normal physiological role in tissues growing by cell division, perhaps as a growth regulator. (silverchair.com)
  • Fish is a technique used to identify and localize the presence or absence of specific dna sequences on cells and tissues. (web.app)
  • In summary, fluorochrome detection is a powerful technique used to identify and quantify specific biomolecules in cells and tissues. (dadangoray.com)
  • They can be used to label and identify specific molecules or structures within cells or tissues. (dadangoray.com)
  • We had analyzed circRNA high-throughout sequencing from human tissues and determined bladder cancer related circRNA-3 (BCRC-3, GenBank: KU921434.1) as a new candidate circRNA derived from PSMD1 gene. (biomedcentral.com)
  • RNAscope technology is highly sensitive and specific due to its double Z-probe design, resulting in a high signal-to-noise ratio of staining in various tissues types and allowing diagnostic pathologists to simultaneously visualize, localize, and quantify biomarker expression, they added. (genomeweb.com)
  • Nearly 60% of the genes with detectable expression exhibit broad patterns reflecting quantitative rather than qualitative differences between tissues. (biomedcentral.com)
  • STAU1 recognizes and associates with cis-acting motifs or localization signals in 3'UTR of target mRNAs. (wikipedia.org)
  • AceView: gene:dpy-21, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView. (nih.gov)
  • This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones. (nih.gov)
  • They can bind to the 3′ untranslated region (3′UTR) of target messenger RNAs (mRNAs) in order to regulate gene expression post-transcriptionally with no sequence specificity but by potential electrostatic interactions with the phosphate backbone of RNA 2 , 3 . (nature.com)
  • Some circRNAs contain miRNA response elements (MREs) and function as competing endogenous RNAs (ceRNAs) to interact with miRNAs and regulate the expression of target mRNAs. (biomedcentral.com)
  • High-resolution imaging also allowed accurate analyses of foci number and subcellular localisation. (nih.gov)
  • Dysregulation of circular RNAs (circRNAs) has recently been found to play an important role in the progression and development of cancers such as non-small cell lung cancer (NSCLC). (biomedcentral.com)
  • Circular RNAs (circRNAs) belong to a class of noncoding and protein-coding RNAs localized to the cytoplasm which originate from both single and multiple exons [ 7 , 8 ]. (biomedcentral.com)
  • Circular RNAs (circRNAs) are a new member of noncoding RNAs (ncRNAs) that have recently been described as key regulators of gene expression. (biomedcentral.com)
  • Circular RNAs (circRNAs), a new member of noncoding RNAs (ncRNAs), have attracted great attentions for their closed continuous loop structure and potential value in clinical work [ 9 , 10 ]. (biomedcentral.com)
  • Microglia cells have been implicated to play an important role in the tumor microenvironment, and we found spatial co-localization of microglia and epithelial-to-mesenchymal transition (EMT) signatures in our patient cohort. (kth.se)
  • In HPV testing, detecting the spatial localization of active HPV in tumor cells is critical in assessing its clinical significance, and the AMPIVIEW™ HPV RNA probes make this possible. (enzo.com)
  • In primary tumors, mutations in driver genes frequently provide a survival advantage and give rise to a dominant clonal population. (spandidos-publications.com)
  • We interrogated their performance for their clinical utility for detection of graft rejection and inflammation by analyzing gene expression microarrays analysis of 163 renal allograft biopsies, and subsequently validated in 40 independent FFPE archived kidney transplant biopsies at a single center. (escholarship.org)
  • Fluorochrome detection refers to a technique used to identify and quantify specific biomolecules using fluorescent dyes. (dadangoray.com)
  • Fluorochrome detection involves using a specific dye that is excited by light of a particular wavelength to emit light at a different wavelength. (dadangoray.com)
  • DNA: Fluorochrome can detect DNA sequences, making it an essential tool in genetic studies such as gene expression analysis. (dadangoray.com)
  • Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. (azolifesciences.com)
  • In contrast, sequences from the 5'UTR through the coding region of either actin gene did not localize the blue product. (umassmed.edu)
  • DVTP nick-end labeling (TUNEL) assay with the In Situ Cell determined according to the manufacturer's protocol. (cdc.gov)
  • In Paper II , we present an assay for spatial RNA quality evaluation, used to estimate the success for tissue specimens before proceeding with more expensive spatial sequencing methods. (kth.se)
  • Swr1 is required for the deposition of histone H2AZ at specific chromosome locations in vivo, and Swr1 and H2AZ commonly regulate a subset of yeast genes. (sdbonline.org)
  • Recent studies have revealed that variants of histone H2A and histone H3 play important roles not only in gene expression but also in the repair of DNA breaks and the assembly of chromosome centromeres. (sdbonline.org)
  • Further studies indicate that the CCND2 gene is present at chromosome band 12p13 and CCND2 is overexpressed in most GCTs, including CIS. (medscape.com)
  • De plus, la qualité de ces résultats avec une sonde radioactive suggère qu'il serait possible d'utiliser l'hybridation in situ pour des applications telles que la localisation et la quantification d'une invasion microbienne de l'endorhizosphère ou du rhizoplan en utilisant des sondes ARN spécifiques de champignons ou de bactéries, et en comptant le nombre de signaux radioactifs par cellule. (agronomy-journal.org)
  • Moreover, the quality of these results with a radioactive probe makes it possible to consider using ISH for such rhizospheric applications as localizing and quantifying a microbial invasion of the endorhizosphere or the rhizoplan by using bacterial- or fungal-specific RNA probes, and counting the number of radioactive dots per cell. (agronomy-journal.org)
  • However, major artifacts observed with a digoxegin RNA cold probe makes it necessary to recommend the use of a radioactive RNA probe for these prospects. (agronomy-journal.org)
  • have developed a new method to detect RNA viruses based on the triplex-forming probe technology. (azolifesciences.com)
  • We present the first definitive report of C9orf72 repeat sense and antisense RNA foci using a series of C9FTLD cases, and neurodegenerative disease and normal controls. (nih.gov)
  • These data establish that sense and antisense C9orf72 repeat RNA foci are a consistent and specific feature of C9FTLD, providing new insight into the pathogenesis of C9FTLD. (nih.gov)
  • STAU1 plays a significant role in RNA metabolism and affects crucial cellular functions. (wikipedia.org)
  • Using nascent RNA expression profiles, we identified a total of 1,768 lncRNAs, of which 58% were identified as novel lncRNAs in P. falciparum . (biorxiv.org)
  • Currently, a range of probes can be synthesized to locate and quantify specific short RNAs, genes, entire chromosomes, and even cells (Evanko 2007 ). (springer.com)
  • Conclusions: Target gene expression amplification across a custom set of genes can identify AR independent of histology, and quantify inflammation from archival kidney transplant biopsy tissue, providing a new tool for clinical correlation and outcome analysis of kidney allografts, without the need for prospective kidney biopsy biobanking efforts. (escholarship.org)
  • Double-stranded RNA-binding protein Staufen homolog 1 is a protein that in humans is encoded by the STAU1 gene. (wikipedia.org)
  • We present evidence for the de novo origin of the Wookiee wookiee protein-coding gene GLABR since their divergence from humans. (ubc.ca)
  • Prior to serum induction no c-fos RNA is detected, but these transcripts localize to two dots in the interphase nucleus after induction. (northwestern.edu)
  • Nanos family is characterized by two specific Cys-Cys-His-Cys zinc finger motifs at the carboxy-terminal region which present a regular spacing between the Cys and the His residues. (nature.com)
  • A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. (nih.gov)
  • We determined and documented embryonic expression patterns for 6,003 (44%) of the 13,659 protein-coding genes identified in the Drosophila melanogaster genome with over 70,000 images and controlled vocabulary annotations. (biomedcentral.com)
  • Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. (azolifesciences.com)
  • Identifying specific afferent neurons will help in understanding their physiology. (jove.com)
  • RNA foci were most abundant in the frontal cortex, where 51 % of neurons contained foci. (nih.gov)
  • RNA foci also occurred in astrocytes, microglia and oligodendrocytes but to a lesser degree than in neurons. (nih.gov)
  • RNA foci were observed in both TDP-43- and p62-inclusion bearing neurons, but not at a greater frequency than expected by chance. (nih.gov)
  • Furthermore, synaptic potentiation of thalamic inputs to the LA during fear conditioning is learning-specific, postsynaptically mediated and highly localized to Arc -expressing neurons. (nature.com)
  • Using semi-quantitative reverse-transcription polymerase chain reaction (RT-PCR) and western blots experiments, we compared changes in ETS-1 and ETS-2 expression, their protein levels, and the regulation of some of their target gene expressions at different stages of the ocular tumoral progression in the transgenic mouse model, Tyrp-1-TAg, with those in normal eyes from control mice of the same age. (molvis.org)
  • Southern and Northern blots and reverse-transcription PCR analyses indicate that the same rhodopsin gene is expressed in the retina and the brain but not in the pineal organ of ayu. (bioone.org)
  • Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. (wikipedia.org)
  • In Paper I , we describe a protocol for transcript profiling of single cells, capable of measuring the relative expression levels for genes of interest. (kth.se)
  • In Paper IV , we present an approach to investigate in situ transcript derivedinferred copy number variation (iCNV) profiles based on spatial transcriptomics data. (kth.se)
  • Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. (nih.gov)
  • The avian gene 9E3/CEF-4, a member of the superfamily of genes that includes KC and gro, is expressed abundantly in exponentially growing cultures of chick embryo fibroblasts (CEFs) and at high levels in CEFs transformed with Rous sarcoma virus (RSV). (silverchair.com)
  • Enzo's AMPIVIEW™ RNA products combine the precision of targeted, sequence-specific probes with the superior sensitivity of its novel LoopRNA™ ISH technology. (enzo.com)
  • The AMPIVIEW™ RNA platform is flexible and adaptable, with established manual or automated workflows. (enzo.com)
  • The complex life cycle of Plasmodium falciparum requires coordinated gene expression regulation to allow host cell invasion, transmission, and immune evasion. (biorxiv.org)
  • ChIRP-seq of candidate lncRNAs revealed that lncRNA occupancy sites within the parasite genome are focal and sequence-specific with a particular enrichment for several parasite-specific gene families, including those involved in pathogenesis, erythrocyte remodeling, and regulation of sexual differentiation. (biorxiv.org)
  • The conserved histone variant H2AZ has an important role in the regulation of gene expression and the establishment of a buffer to the spread of silent heterochromatin. (sdbonline.org)
  • Control of gene expression at transcription and translation level: Regulation of phages, viruses, prokaryotic and eukaryotic gene expression, role of chromatin in regulating gene expression and gene silencing. (pathfinderacademy.in)
  • Regulation of gene expression in time and space is a major driving force of this process. (biomedcentral.com)
  • This synthetic genetic interaction is seen at the level of single genes and acts downstream of promoter nucleosome reorganization. (sdbonline.org)
  • However, this cascade of transcripts is unlikely to be regulated by the limited number of identified parasite-specific transcription factors. (biorxiv.org)
  • We have also compared the localization of c-fos transcripts with the speckled nuclear regions that are enriched in snRNPs and the non-snRNP splicing factor SC-35. (northwestern.edu)
  • Although the FPPE samples yielded fewer transcripts and genes compared to FF, there was a high agreement in gene expression between paired anatomical areas for FFPE and FF samples. (kth.se)
  • Additionally, the genome-wide occupancy of several candidate nuclear lncRNAs was explored using Chromatin Isolation by RNA Purification (ChIRP). (biorxiv.org)
  • However, the range of gene expression patterns, the extent of the correlation of expression with function, and the classes of genes whose spatial expression are tightly regulated have been unclear due to the lack of an unbiased, genome-wide survey of gene expression patterns. (biomedcentral.com)
  • It can visualize specific cytogenetic abnormalities copy number aberrations such as chromosomal deletion, amplification, and translocation. (web.app)
  • Abnova provides over 600 fish probes for identification of gene amplification, split. (web.app)
  • Abnova provides over 600 fish probes for identification of gene amplification, split, translocation, subtelomere aberration, prenatal chromosomal aberration and chromosomal markers. (web.app)
  • Results: A QPCR (Fluidigm) and a barcoded oligo-based (NanoString) gene expression platform were compared for evaluation of amplification of gene expression signal for 19 genes from degraded RNA extracted from FFPE biopsy sections by a set protocol. (escholarship.org)
  • ISH confirmed a high degree of correlation of signal amplification and tissue localization. (escholarship.org)
  • Transcriptomic analysis on 72 h-exposed fetal testis explants revealed 187 differentially expressed genes (DEGs), including genes involved in steroid synthesis and toxic substance response. (biomedcentral.com)
  • We describe the tissue specificity of gene expression at each stage range using selected terms from a controlled vocabulary (CV) for embryo anatomy [ 18 ]. (biomedcentral.com)
  • Capsid gene delivery into the striatum of mouse brain or interskeletal muscle resulted in cell death and inflammation, likely through capsid-induced apoptosis in vivo. (cdc.gov)
  • Based on phylogenetic and synteny analyses, this study reveals that nanos1 gene has undergone multiple duplications and gene copies losses in Vertebrates. (nature.com)
  • To identify the photoreceptive molecule that regulates photoperiodic responses, in the present study, we have cloned and characterized the cDNA encoding an opsin gene expressed in the ayu brain, a putative site of the photoreceptor for photoperiodism. (bioone.org)
  • The main STAU1 variants have double-stranded RNA-binding domains (dsRBD), a microtubule-binding domain (TBD), and a STAU1-swapping motif (SSM). (wikipedia.org)
  • The study of PSCs has relied on an anatomy-based approach, as the identities of cell-specific PSC molecular markers have remained elusive. (elifesciences.org)
  • Using a newly generated transgenic mouse in which PSCs are specifically labeled, we show that PSCs have a unique molecular signature that includes genes known to play critical roles in PSCs and synapses. (elifesciences.org)
  • This has been due to the absence of a cell-specific molecular marker with which PSCs can be identified, isolated, and genetically manipulated. (elifesciences.org)
  • Taken together, our findings validate the immediate-early gene Arc as a molecular marker for the LA neuronal ensemble recruited during fear learning. (nature.com)
  • Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies. (escholarship.org)
  • 2017). In this dataset, we identified and characterized the Liver-Specific Protein 2 (LISP2) protein as an early molecular marker of liver stage development. (elifesciences.org)
  • A dualcolor, dualfusion approach is commonly used and can detect all bcrabl1 fusions with excellent sensitivity and specificity including cytogenetically cryptic translocations fig. Fish is a cytogenetic technique used to detect and localize the presence or absence of specific. (web.app)
  • By emitting fluorescent light when exposed to specific wavelengths of light, fluorochromes have become indispensable tools in the fields of biology and medicine. (dadangoray.com)
  • Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis. (nih.gov)
  • To begin, we hypothesize that distinct morphological features, in other words, hairiness are a result of Wookiee specific protein-coding gene(s). (ubc.ca)
  • In a normal lymph node that displays both distinct gene expression patterns and histological landmarks, we observed a neutral iCNV profile. (kth.se)
  • For instance, circFGFR1 may interact directly with miR-381-3p and function as a miRNA sponge to upregulate expression of miR-381-3p target gene C-X-C motif chemokine receptor 4, which enhances NSCLC progression as well as resistance to anti-programmed cell death 1-based therapy [ 11 ]. (biomedcentral.com)
  • This was revealed by co-hybridizing, in situ, fluorochrome-conjugated oligonucleotide probes specific for each isoform. (umassmed.edu)