Loading...
  • molecules
  • The antigenic molecules that activate gamma delta T cells are still largely unknown. (wikipedia.org)
  • However, γδ T cells are peculiar in that they do not seem to require antigen processing and major-histocompatibility-complex (MHC) presentation of peptide epitopes, although some recognize MHC class Ib molecules. (wikipedia.org)
  • For example, according to this paradigm, large numbers of (human) Vγ9/Vδ2 T cells respond within hours to common molecules produced by microbes, and highly restricted intraepithelial Vδ1 T cells will respond to stressed epithelial cells bearing sentinels of danger. (wikipedia.org)
  • pathogens
  • When mature they are divided into functionally distinct subsets that obey their own (mostly unknown) rules and that have countless direct and indirect effects on healthy tissues and immune cells, on pathogens and tissues enduring infections and the host responses to them. (wikipedia.org)
  • genome
  • One advantage and weakness of the Hayday nomenclature is that it is based on the gene order in the B6 genome, but this might not apply to other strains. (wikipedia.org)
  • innate
  • The conditions that lead to responses of gamma delta T cells are not fully understood, and current concepts of them as 'first line of defense', 'regulatory cells', or 'bridge between innate and adaptive responses' only address facets of their complex behavior. (wikipedia.org)