Gene protein complexes carrier proteins. Medical search. Frequent questions

Mutations in the gene for the antennapedia homeodomain protein are associated with the conversion of antenna to leg or leg to antenna DROSOPHILA. (lookformedical.com)
Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. (lookformedical.com)
Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene. (jax.org)
Mutations in the gene coding for survival of motor neuron 1 protein may result in SPINAL MUSCULAR ATROPHIES OF CHILDHOOD. (harvard.edu)
In addition, knowledge of protein structure may prompt potential partners for protein interaction and thus encourage researchers to develop or improve new enzymes or antibodies, or, for example, to explain the phenotype of the mutations performed or to help determine the location of the mutations in order to change specific phenotypes. (custom-essay.org)
Mutations in the SLC25A19 gene cause Amish lethal microcephaly. (medlineplus.gov)
which means both copies of the gene in each cell have mutations. (medlineplus.gov)
HPS types 7, 8 and 9 are due to mutations in genes encoding subunits of BLOC-1, a complex required for the generation of tubular cargo carriers destined for melanosomes. (chop.edu)
HPS types 3, 5 and 6 are due to mutations in genes encoding subunits of BLOC-2, a complex that directs BLOC-1-dependent cargo carriers with melanosomes. (chop.edu)
Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. (prospecbio.com)
Diagnosis of Mutations in the dystrophin gene can cause Duchenne these disorders is based on clinical presentation, muscular dystrophy or Becker muscular dystrophy. (who.int)
90% of cases, mutations that from mutation in the dystrophin gene (located on short disrupt the reading frame (frame shift) lead to arm of X chromosome, Xp21). (who.int)

Though its whole genome has not been sequenced, the coding sequences of some genes have been sequenced: Genes were found in this organism that encode the biotin carboxylase, carboxyl transferase and biotin carboxyl carrier protein. (wikipedia.org)
It has a cluster of genes, called fox genes, that encode membrane proteins that are similar to cytochrome c oxidase. (wikipedia.org)
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. (lookformedical.com)
Many genes encode protein products, meaning that they specify the sequence of amino acids used to build a particular protein. (khanacademy.org)
Importantly, not all genes encode protein products. (khanacademy.org)

Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were performed on differentially expressed genes (DEGs). (spandidos-publications.com)

Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus. (lookformedical.com)
Proteins are constructed through an intricate action blueprinted and carried out by the nucleic acids deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). (biologydictionary.net)

This complex molecule can be seen below. (biologydictionary.net)
The process of gene expression is a combination of transcription and translation , where a sequence of DNA code provides the information necessary to construct a new protein molecule from available cellular materials. (biologydictionary.net)
Usually DNA remains as a giant molecule packed in the cells nucleus and is composed of proteins in the chromatin fibers. (scialert.net)

We tested the hypothesis that gene expression of sex steroid metabolizing enzymes and receptors would vary seasonally in skeletal muscle and these changes would differ between a migrant and resident life history strategy. (bvsalud.org)
Between these two subspecies, patterns of plasma testosterone and androgen receptors appear to be conserved, however estrogen receptor gene expression appears to have diverged. (bvsalud.org)

By comparison, we found that various genes associated with acyl editing, fatty acid β-oxidation, triacylglycerol assembly and oil-body formation had greater expression levels at middle developmental stage (38 DAP), which are consistent with the fast accumulation of EFA in V. galamensis developing seed, implying their fundamental roles in EFA production. (researchsquare.com)
malonyl CoA-acyl carrier protein transacylase, putative [Geobacter sulf. (yeastrc.org)
AF237571_1 malonyl CoA-acyl carrier protein transacylase precursor [Plasmo. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Anaplasma phagocytophilu. (yeastrc.org)
acyl-carrier-protein S-malonyltransferase [Bacillus anthracis str. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Campylobacter jejuni RM1. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Carboxydothermus hydroge. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Colwellia psychrerythrae. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Dehalococcoides ethenoge. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Ehrlichia chaffeensis st. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Geobacter sulfurreducens. (yeastrc.org)
malonyl CoA-acyl carrier protein transacylase [Neorickettsia sennetsu s. (yeastrc.org)
PREDICTED: similar to Malonyl CoA-acyl carrier protein transacylase, mi. (yeastrc.org)
acyl-carrier-protein S-malonyltransferase [Ruegeria pomeroyi DSS-3], gi. (yeastrc.org)
In the presence of citrate, the transferase mediates the formation of citryl-S-acyl carrier protein by acyl exchange and liberation of acetate. (dairy-journal.org)

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism. (lookformedical.com)
For this reason, specialists are interested in anticipating a protein abnormal to the host organism in the carrier bacterium so that a drug can be developed in time. (custom-essay.org)

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. (lookformedical.com)
Several other genetic backgrounds result in enlargement of the haltere significantly beyond the normal range of haploinsufficient phenotypes, suggesting genetic variation in cofactors that mediate homeotic protein function. (lookformedical.com)
If uninformative deletion/duplication genetic tests have resulted, direct sequencing of the dystrophin gene is a viable option. (medscape.com)
This complex coordination can be disrupted through a genetic defect in an enzyme. (newworldencyclopedia.org)
Carrier screening is a term used to describe genetic testing that is performed on an individual who does not have any overt phenotype for a genetic disorder but may have one variant allele within a gene(s) associated with a diagnosis. (acog.org)
When an individual is found to be a carrier for a genetic condition, his or her relatives are at risk of carrying the same mutation. (acog.org)
If an individual is found to be a carrier for a specific condition, the patient's reproductive partner should be offered testing in order to receive informed genetic counseling about potential reproductive outcomes. (acog.org)
If both partners are found to be carriers of a genetic condition, genetic counseling should be offered. (acog.org)
What follows is a detailed discussion of some of the more common genetic conditions for which carrier screening is recommended in at least some segments of the population. (acog.org)
Individuals with a positive family history of a genetic condition should be offered carrier screening for the specific condition and may benefit from genetic counseling. (acog.org)
The genetic organization of genes encoding proteins involved in citrate lyase activity of Leuconostoc mesenteroides is des-cribed. (dairy-journal.org)

The prin2.2 and csp41b-2 single mutants displayed pale phenotypes, abnormal chloroplasts with reduced transcript levels of photosynthesis genes and defects in embryo development. (frontiersin.org)

in the absence of a particular enzyme, the abnormal or unregulated synthesis of complex molecules might result. (newworldencyclopedia.org)
inborn errors of metabolism are caused by mutant genes that produce abnormal enzymes whose function is altered. (newworldencyclopedia.org)
Researchers believe that this mutation interferes with the transport of thiamine pyrophosphate into the mitochondria and the activity of the alpha-ketoglutarate dehydrogenase complex, resulting in the abnormal brain development and alpha-ketoglutaric aciduria seen in Amish lethal microcephaly. (medlineplus.gov)

Proteins found in the nucleus of a cell. (lookformedical.com)
In their latent state, MondoA:Mlx complexes localize to the outer mitochondrial membrane, yet shuttle between the mitochondria and the nucleus. (duke.edu)
We show that MondoA:Mlx complexes accumulate in the nucleus in response to glucose and 2-deoxyglucose (2-DG). (duke.edu)
The gradual conversion from endosymbiont to organelle during the course of evolution has clearly been accompanied by a dramatic reduction in genome size as the chloroplasts lost most of their genes to the nucleus. (frontiersin.org)

We later identified PIAS (protein inhibitor of activated STAT)xalpha as a DJ-1-binding protein, and found that DJ-1 restored androgen receptor (AR) transcription activity that was repressed by PIASxalpha. (nih.gov)
In addition to the cellular energy sensor AMP kinase, the peroxisome proliferator-activated receptor cofactors PGC1α ( 5 , 6 , 7 ) and possibly PGC1β ( 8 ) activate mitochondrial biogenesis and increase OXPHOS gene expression by increasing the transcription, translation, and activation of the transcription factors necessary for mitochondrial DNA (mtDNA) replication. (diabetesjournals.org)
The citric type, pin-pointed a available interface( complex), describes an Second subcellular transcription within a receptor path-finding. (evakoch.com)
Circular RNAs (circRNAs) are closed, long, non-coding RNAs that are formed via direct reverse splicing of precursor mRNA that function by regulating RNA transcription and protein production, as well as sponging miRNAs ( 4 ). (spandidos-publications.com)

Cellular metabolism, involving the synthesis and breakdown of complex organic molecules, requires harmonious coordination of the various enzymes, biochemical reactions, and so forth. (newworldencyclopedia.org)
Protein prediction is an incredibly important goal since it allows to simplify biotechnological research in the process of designing new drugs or enzymes. (custom-essay.org)
In complexes, the other enzymes affect cleaved CBF1( or RBPJkappa), while in channels they are required Lag-1, immediately that the m ' CSL ' demonstrates separated been to this produced feature experience breast. (evakoch.com)
RNA enzymes may observe from also translocated proteins, they may phosphorylate suggested in proteins with delayed strategies, or they may outline known in membranes of factor factors. (evakoch.com)
This compound is involved in the activity of a group of mitochondrial enzymes called the dehydrogenase complexes, one of which is the alpha-ketoglutarate dehydrogenase complex. (medlineplus.gov)
A very natural place to study gene detecting and metabolizing lactose, it is known that the overall regulation is in the metabolism of the cell, and then specifically in effect of expressing the lac genes in vain is a drop in the growth rate the regulation of genes that code for enzymes and transporter of as much as 5% [1,6]. (lu.se)

MicroRNAs (miRNAs) are short non-coding RNAs that posttranscriptionally regulate gene expression inside the cell. (frontiersin.org)
For instance, some genes specify ribosomal RNAs ( rRNAs ), which serve as structural components of ribosomes, or transfer RNAs ( tRNAs ), cloverleaf-shaped RNA molecules that bring amino acids to the ribosome for protein synthesis. (khanacademy.org)
Still other RNA molecules, such as tiny microRNAs ( miRNAs ), act as regulators of other genes, and new types of non-protein-coding RNAs are being discovered all the time. (khanacademy.org)

In humans the protein is encoded by a single gene found near the inversion telomere of a large inverted region of CHROMOSOME 5. (harvard.edu)

Transcriptome data were further confirmed by quantitative real-time PCR for twelve key genes in EFA biosynthesis. (researchsquare.com)
The process is known as protein biosynthesis and involves the construction of protein chains from individual amino acids in a particular sequence. (biologydictionary.net)
Iron-Dependent Regulation of Molybdenum Cofactor Biosynthesis Genes in Escherichia coli. (mpg.de)

The PEP enzyme recognizes the -10 and -35 cis -elements, similar to those found in bacterial promoters whereas the NEP enzyme recognizes the YRTA-motif, which can also be found upstream of several genes with PEP promoters indicating that these genes can be transcribed by both polymerases ( Pfannschmidt and Liere, 2005 ). (frontiersin.org)
A GWAS study from Sarah Tishkoff's lab at the University of Pennsylvania identified several genes that show altered expression in light vs. dark skinned Africans. (chop.edu)

Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. (lookformedical.com)

A metabolic disorder is any disease or disorder that negatively affects the biochemical reactions through which individual animal cells process nutrient molecules (such as the components of carbohydrates , proteins , and fats ) to yield energy or perform the functions necessary to sustain life (such as building complex molecules and creating cellular structure). (newworldencyclopedia.org)
Traditionally, prediction of the functions of bacterial proteins is carried out for poorly studied molecules or hypothetical proteins predicted based on these genome sequences. (custom-essay.org)
They act as binding molecules and carrier molecules allowing for transport and storage of atoms and molecules throughout the body. (biologydictionary.net)

We identify thioredoxin-interacting protein (TXNIP) as a direct and glucose-regulated MondoA:Mlx transcriptional target. (duke.edu)
These studies suggest a key role for MondoA:Mlx complexes in the adaptive transcriptional response to changes in extracellular glucose concentration and peripheral glucose uptake. (duke.edu)
MicroRNAs (miRNAs or miRs) are involved in the post-transcriptional regulation of gene expression via complete or partial base pairing with the 3′untranslated region of target genes ( 3 ). (spandidos-publications.com)
Transcriptional regulation of the genes in metabolic pathways is a highly successful strategy, which is virtually universal in microorganisms. (lu.se)
With a minimalist model of metabolism, cell growth and transcriptional regulation in a microorganism, we explore how the interaction between environmental conditions and gene regulation set the growth rate of cells in the phase of exponential growth. (lu.se)
INTRODUCTION broken, which in realistic situations can severly constrain the Transcriptional regulation of effector genes is a highly successful regulatory options. (lu.se)

Functional annotation resulted in the identification of almost all genes involved in diverse lipid-metabolic pathways, including the novel fatty acid desaturase/epoxygenase, diacylglycerol acyltransferase 1 and 2, and phospholipid:diacylglycerol acyltransferases. (researchsquare.com)

Six genes involved in oxidative phosphorylation (OXPHOS) decreased. (diabetesjournals.org)
Two recent microarray studies have shown that genes involved in oxidative phosphorylation (OXPHOS) exhibit reduced expression levels in the skeletal muscle of type 2 diabetic subjects and prediabetic subjects. (diabetesjournals.org)
Interestingly, the first genome-wide CRISPR interference/activation screens to discover susceptibility genes of oxidative stress in induced pluripotent stem cell (iPSC)-derived human neurons identified PSAP. (nature.com)

The PI3K/Akt/mTOR signaling pathway is a key regulator of diverse physiological functions such as proliferation, global protein, and lipid synthesis as well as many metabolic pathways interacting to increase secretory capabilities. (go.jp)
For instance, how can cells control the diverse patterns of glycosylation of various secretory proteins in the endoplasmic reticulum and Golgi in an orderly manner with high accuracy? (go.jp)

Drosha, RNase III, and DGCR8, the RNA-binding protein, further process pri-miRNAs into stem-loop structured precursor miRNAs (pre-miRNAs) of ~70 nt ( 29 ). (frontiersin.org)

and lysosomal proteins, such as the transporter MFSD12, that impact melanogenesis indirectly. (chop.edu)

Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (rndsystems.com)
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
Serial dilutions of Mouse IL-11 Recombinant Protein were added to B9 cells. (cellsignal.com)
The purity of Mouse IL-11 Recombinant Protein was determined by SDS-PAGE of 1 µg reduced (+) and non-reduced (-) recombinant mIL-11 and staining with Coomassie Blue. (cellsignal.com)
Mouse IL-11 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/ml which can be further diluted in aqueous solutions as needed. (cellsignal.com)

Most metabolic disorders are inherited from one or both parents who carry a defective gene that regulates a particular protein in a class of the body's cells. (newworldencyclopedia.org)
A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)

We found that the FERM domain in the tail region, which is known to bind to lipids as well as other proteins, is essential for both nuclear and chloroplast positioning, whereas the proximal MyTH4 domain plays a supporting role in chloroplast transport. (go.jp)
We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)

UFD1L forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. (prospecbio.com)
In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. (prospecbio.com)

Because the environment encountered within a living host will be quite different from the external environment, pathogens must be able to regulate the necessary genes in coordination as they move from the environment to the host and from one host niche to another. (cdc.gov)
in this way, vesicle-free miRNA may regulate cell-to-cell communication including the regulation of gene expression and cellular signaling. (frontiersin.org)
the team and its collaborators have shown that the products of HPS-associated genes in skin melanocytes regulate two pathways of membrane protein transport from endosomes to newly forming melanosomes and a retrograde pathway from melanosomes. (chop.edu)

The source of information for the prediction can be the homology of nucleotide sequences, gene expression profiles or phylogenetic and phenotypic profiles. (custom-essay.org)
This type of RNA is called a messenger RNA ( mRNA ), as it serves as a messenger between DNA and the ribosomes, molecular machines that read mRNA sequences and use them to build proteins. (khanacademy.org)

Full length native protein (purified) corresponding to Cow Cytochrome C. Bovine heart Cytochrome C. (abcam.com)

Cytosine modifications directly affect the positioning of nucleosomes (the first level of chromatin organization into chromosome involving the DNA chain wound around a core of 8 histone proteins), and recruit chromatin-modifying complexes that modify histones. (i-sis.org.uk)
A chromosome may contain tens of thousands of genes , each providing instructions on how to make a particular product needed by the cell. (khanacademy.org)

Proteins in the SLC family transport various compounds across the membranes surrounding the cell and its component parts. (medlineplus.gov)
The lab employs a variety of approaches to probe how BLOC-1 interacts with membranes and with other HPS-encoded protein complexes to better understand its mechanism of action. (chop.edu)

In mammals, most histone proteins are lost during sperm development, eventually to be replaced by protamines. (i-sis.org.uk)
The development of tools to manipulate the mouse genome, including knockout and transgenic technology, has revolutionized our ability to explore gene function in mammals. (elifesciences.org)

The amino acid residue sequence of all three proteins that are coded for by these genes have also been sequenced using microsequencing. (wikipedia.org)
Each protein is the combination of a specific sequence of amino acids, built according to the blueprint contained within the DNA. (biologydictionary.net)
All known individuals with Amish lethal microcephaly have a mutation in which the protein building block (amino acid) alanine is substituted for the amino acid glycine at position 177 of the SLC25A19 protein, written as Gly177Ala or G177A. (medlineplus.gov)
A mouse model of HPS bears a point mutation altering a single amino acid within the VPS33A subunit of the HOPS/CORVET endolysosomal tethering complex. (chop.edu)

However, we now have a number of methods that allow identification of genes critical for survival in a host as well as methods that allow direct measurement of gene expression during interaction with a host. (cdc.gov)
Survival of Motor Neuron 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
This graph shows the total number of publications written about "Survival of Motor Neuron 1 Protein" by people in Harvard Catalyst Profiles by year, and whether "Survival of Motor Neuron 1 Protein" was a major or minor topic of these publication. (harvard.edu)
Below are the most recent publications written about "Survival of Motor Neuron 1 Protein" by people in Profiles. (harvard.edu)
Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy. (harvard.edu)
Survival Motor Neuron Gene Copy Number Analysis by Exome Sequencing: Assisting Spinal Muscular Atrophy Diagnosis and Carrier Screening. (harvard.edu)

In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. (nih.gov)
What complicates matters is that every known epigenetic information carrier interacts with every other carrier. (i-sis.org.uk)

Eukaryote genomes are packaged into a nucleoprotein complex known as chromatin. (i-sis.org.uk)

There is new enthusiasm to consider newborn screening given the promise of earlier treatment with steroids, molecular therapy, or gene therapy. (medscape.com)
How DNA carries this information, and how it is put into action by cells and organisms, is complex, fascinating, and fairly mind-blowing, and we'll explore it in more detail in the section on molecular biology . (khanacademy.org)
This progression from DNA to RNA to protein is called the " central dogma " of molecular biology. (khanacademy.org)
The form of this complex can be controlled by variations of DNA`s molecular weight and types. (scialert.net)
In this paper is demonstrated that one example of the biologically important and molecular self-assembling complex system is a collagen-DNA ordered aggregates spontaneously formed in aqueous solutions. (scialert.net)
According to molecular biology data, the assembly of the complex between collagen and DNA determines the stability of DNA against the nucleases and indicates a development of autoimmune reaction (Poverenny, 1968). (scialert.net)
Accordingly it is very important study the principles of organization of the molecular complex between collagen and DNA. (scialert.net)
Mrevlishvili and Svintradze (2005a, b) is demonstrated that one example of biological important and molecular self-assembly complex system is the collagen-DNA ordered aggregate which is spontaneously formed in aqueous solution. (scialert.net)
According to the molecular model (Mrevlishvili and Svintradze, 2005b) DNA containing well-arranged phosphate groups helps to make this complex and these groups and water layers play key roles during collagen-DNA ordered aggregation in aqueous solution. (scialert.net)

Biodistribution of onasemnogene abeparvovec DNA, mRNA and SMN protein in human tissue. (harvard.edu)

60% of human protein-coding genes, mostly by binding to the 3′- untranslated region (3′UTR) of the target mRNAs ( 5 ) and, therefore, miRNAs affect gene expression networks of a variety of biological processes including development, apoptosis, proliferation, and metabolism ( 1 , 2 ). (frontiersin.org)

To further characterize the function of DJ-1, we cloned cDNA encoding a novel DJ-1-binding protein, DJBP, by a yeast two-hybrid system. (nih.gov)
We hypothesized a HFD may affect expression of genes involved in mitochondrial function and biogenesis. (diabetesjournals.org)
A SMN complex protein that is essential for the function of the SMN protein complex. (harvard.edu)
This essay on Predicting Bacterial Proteins' Structure and Function was written by a student just like you. (custom-essay.org)
Here, the function of regulation is quite clear: expressing energy and carbon, that a number around 0.2% would be the right genes at the right time will enable the cell to make the expected, and that the difference is more or less specific to the lac most of the resources within its reach, by maximizing the uptake operon [7]. (lu.se)

Unless otherwise stated all data on this page refer to the human proteins. (guidetopharmacology.org)
Gene information is provided for human (Hs), mouse (Mm) and rat (Rn). (guidetopharmacology.org)

Soon after fertilization, the vast majority of methylcytosine in sperm is converted by the Tet3 enzyme to hydroxymethylcytosine that gets lost by dilution during replication, effectively erasing cytosine methylation patterns except for a subset that is maintained, including those of some imprinted genes. (i-sis.org.uk)
Therapies may include a restrictive diet, dietary supplements, and toxin-removal procedures, as well as enzyme replacement, gene transfer, or organ transplantation. (newworldencyclopedia.org)
Every antibody, enzyme and chemical messenger is created from protein. (biologydictionary.net)
During initiation , RNA polymerase (an enzyme) attaches to a 'promotor' sequence which indicates the start of the section of gene that is to be copied. (biologydictionary.net)

RNA polymerase II mainly transcribes microRNA genes as primary miRNA transcripts (pri-miRNAs) that contain 5′cap and 3′poly(A) tails ( 28 ). (frontiersin.org)
We quantified annual changes in plasma testosterone and gene expression in pectoralis and gastrocnemius skeletal muscles using quantitative polymerase chain reaction (qPCR) in free-living migrant (Zonotrichia leucophrys gambelii) and resident (Z. l. nuttalli) subspecies of white-crowned sparrow during breeding, pre-basic molt, and wintering life history stages. (bvsalud.org)

Pigment cell-specific transmembrane proteins SLC45A2 and OCA2 are a transporter and channel, respectively, that modulate melanosome pH at different stages of melanosome maturation and that are targets of mutation in different forms of oculocutaneous albinism. (chop.edu)

Biotin carboxylase, carboxyl transferase and biotin carboxyl carrier protein could likely be a complex of proteins that help fix carbon dioxide for autotrophy. (wikipedia.org)

one was SDHB in complex II and a mitochondrial carrier protein SLC25A12. (diabetesjournals.org)
Combined, these results suggest a mechanism whereby HFD downregulates genes necessary for OXPHOS and mitochondrial biogenesis. (diabetesjournals.org)

Scholars@Duke publication: Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. (duke.edu)
In this article, we consider whether MondoA:Mlx complexes have a broader role in sensing and responding to glucose status. (duke.edu)
Furthermore, MondoA:Mlx complexes, via their regulation of TXNIP, are potent negative regulators of glucose uptake. (duke.edu)

A second group of methods, which includes DNA microarrays and proteomics, have advantages that overcome the limitations implicit in signature-tagged mutagenesis and in vivo expression technology, namely, the ability to directly measure expression (gene or protein) levels on a true genome-wide scale, but their application to analysis of bacterial pathogens during real infections is still in its infancy. (cdc.gov)

It was found that DJBP repressed a testosterone-dependent AR transactivation activity in monkey Cos1 cells by recruiting histone deacetylase (HDAC) complex, including HDAC1 and mSin3, and that DJ-1 partially restored its repressed activity by abrogating DJBP-HDAC complex. (nih.gov)

Furthermore, a co-immunoprecipitation assay showed that the formation of a ternary complex between DJ-1, DJBP, and AR occurred in cells in which DJ-1 bound to the AR via DJBP. (nih.gov)
The transient assay of selected genes resulted in a synergistic increase of EFA-enriched TAG accumulation in tobacco leaves. (researchsquare.com)

Unusually low levels of triglycerides can be present in disease states, producing syndromes of malabsorption in addition to patients who carry genes for familial hypobetalipoproteinemia . (medscape.com)

S. metallicus up-regulates genes that help it grow in environments with higher sulfur and iron concentrations. (wikipedia.org)

they are not used to synthesize proteins. (biologydictionary.net)

In silico analysis of available array data showed that a large number of genes traditionally classified as PEP dependent genes are transcribed during early embryo development from the pre-globular stage to the mature-green-stage. (frontiersin.org)

cDNA of the fox genes that were known to be in other sulfur oxidizing cells were used to test the presence of the fox genes in Sulfolobus metallicus. (wikipedia.org)

Information about carrier screening should be provided to every pregnant woman. (acog.org)
Carrier screening and counseling ideally should be performed before pregnancy because this enables couples to learn about their reproductive risk and consider the most complete range of reproductive options. (acog.org)
The patient should be encouraged to inform his or her relatives of the risk and the availability of carrier screening. (acog.org)
Carrier screening and counseling ideally should be performed before pregnancy. (acog.org)
Carrier screening for a particular condition generally should be performed only once in a person's lifetime, and the results should be documented in the patient's health record. (acog.org)
Prenatal carrier screening does not replace newborn screening, nor does newborn screening replace the potential value of prenatal carrier screening. (acog.org)
If a patient requests carrier screening for a particular condition for which testing is readily available and which reasonably would be considered in another screening strategy, the requested test should be offered to her (regardless of ethnicity and family history) after counseling on the risks, benefits, and limitations of screening. (acog.org)

Anatomy12

Organisms12

Diseases1

Chemicals and Drugs116

Analytical, Diagnostic and Therapeutic Techniques and Equipment35

Phenomena and Processes58

Disciplines and Occupations4

Technology, Industry, Agriculture3

Information Science21

Health Care3

Mutations12

Encode5

Differentially1

Nucleic acids2

Molecule3

Receptors2

Acyl15

Organism2

Genetic11

Phenotypes1

Abnormal3

Nucleus4

Transcription4

Enzymes6

RNAs3

Humans1

Biosynthesis3

Several genes2

Eukaryotic1

Molecules3

Transcriptional6

Fatty1

Oxidative3

Secretory2

Precursor1

Lysosomal1

Recombinant protein5

Metabolic2

Chloroplast2

Nuclear2

Regulate3

Sequences2

Cytochrome1

Chromosome2

Membranes2

Mammals2

Amino4

Survival6

Interacts2

Chromatin1

Molecular9

MRNA1

Metabolism1

Function5

Human2

Enzyme4

Polymerase2

Transporter1

Transferase1

Mitochondrial2

Glucose3

Genome-wide1

Histone1

Assay2

Familial1

Regulates1

Synthesize1

Traditionally1

CDNA1

Screening7