Gene polymorphism restriction fragment length. Medical search. Frequent questions

The aim of this study was to detect carriers of CVM in Holstein population using Polymerase Chain Reaction- Primer-introduced restriction analysis and Restriction Fragment Length Polymorphism (PCR-PIRA and RFLP) methods. (researchgate.net)
Using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method, we tested the genotype distribution of 100 migraine patients in comparison with 120 healthy migraine-free controls from the same geographical region. (scirp.org)
To obtain a better understanding of metabolically active microbial communities, we tested a molecular ecological approach using poly(A) tailing of environmental 16S rRNA, followed by full-length complementary DNA (cDNA) synthesis and sequencing to eliminate potential biases caused by mismatching of polymerase chain reaction (PCR) primer sequences. (frontiersin.org)
Numerous studies on natural microbial communities from a variety of environments have been undertaken using 16S rRNA gene sequencing mediated by polymerase chain reaction (PCR) with oligonucleotide primers. (frontiersin.org)
Polymerase chain reaction/restriction fragment length polymorphism technique (PCR-RFLP) was conducted to determine the genotypes. (medsci.org)
Six proto-oncogenes (K-ras, c-myc, c-fos, c-jun, c-sis, and erbB), as well as the p53 tumor suppressor, were investigated for gene amplification using differential polymerase chain reaction (PCR), while the expression of the proteins produced by these genes was evaluated by Western blot analysis. (cdc.gov)
Polymerase chain reaction-restriction fragment length polymorphism methods were used to genotype DRD2 Taq 1A polymorphism with genomic DNA isolated from whole blood collected at the enrollment. (fluoridealert.org)
C gene polymorphism were genotyped using polymerase chain reaction followed by restriction fragment length polymorphism. (ijp-online.com)
The polymerase chain reaction with mixed oligonucleotide primers targeted for conserved sequences of reported ure genes from other species was used to prepare a DNA probe to detect the V. parahaemolyticus ure gene. (microbiologyresearch.org)
The UTS2 gene polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). (bjbms.org)
Materials and Methods: Associations of seven XRCC3 genotypes, namely rs1799794, rs45603942, rs861530, rs3212057, rs1799796, rs861539 and rs28903081, with the risk of asthma were investigated among 198 patients with asthma and 453 non-asthma controls by polymerase chain reaction-restriction fragment length polymorphism genotyping methodology. (iiarjournals.org)
rs10046) and CYP19A1 ((TTTA)n repeats) polymorphisms and BRCA1 founder mutation using TaqMan allelic discrimination method and polymerase chain reaction based restriction fragment length polymorphism. (biomedcentral.com)
Polymerase chain reaction (PCR) was conducted using groEL PCR-restriction fragment length polymorphism and sequence analysis. (who.int)
Polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) analysis of the ribosomal RNA gene internal transcribed spacer-1 (ITS1) was used. (who.int)

The identified isolates were tested by Coagulase gene RFLP typing. (hindawi.com)
Present study was designed to explore the genetic diversity of plasmodium vivax genotypes based on Pvmsp-3α and Pvmsp - 3β genes using allelic specific nested PCR and RFLP assays markers from field isolates in district Mardan, Pakistan. (scielo.br)
Genetic diversity in nested PCR products was determined by Restriction Fragment Length Polymorphism (RFLP) utilizing Alu1 and PstI restriction enzymes for alpha and beta gene products digestion, respectively. (scielo.br)
O presente estudo foi desenhado para explorar a diversidade genética de genótipos de Plasmodium vivax baseados nos genes Pvmsp-3α e Pvmsp-3β, usando marcadores de ensaios alélicos nested PCR e RFLP de isolados de campo no distrito de Mardan, Paquistão. (scielo.br)
A diversidade genética em produtos de PCR nested foi determinada por polimorfismo de fragmento de restrição (RFLP) utilizando as enzimas de restrição Alu1 e PstI para a digestão dos produtos dos genes alfa e beta, respectivamente. (scielo.br)
Os genes Pvmsp-3β de isolados de P. vivax utilizando PCR/RFLP do Distrito Mardan mostraram um nível notável de diversidade genética nos genes estudados de parasitas circulantes na área de estudo. (scielo.br)
The polymorphism of the Serine-Rich Entamoeba dispar Protein (SREDP) gene among 8 isolates obtained from Iranian cyst carriers were analyzed by a nested PCR-RFLP followed by sequencing of the PCR products. (scialert.net)
In the present study, the genetic variability of E. dispar strains based on the SREDP gene locus was analyzed using RFLP-nested PCR and sequencing of the obtained genes. (scialert.net)
The presence and diversity of ammonia oxidizing bacteria (AOB) and archaea (AOA) were identified by terminal restriction fragment length polymorphism (T-RFLP) based on the amoA gene sequences. (iwaponline.com)
The T-RFLP result of AOA showed the diverse microbial community structure of AOA with three terminal restriction fragments (T-RFs). (iwaponline.com)
Linkage analysis by restriction fragment length polymorphism (RFLP) in multiple family members can be used. (medscape.com)

Five disease genes encoding sarcomeric proteins and associated with familial and classical forms of hypertrophic cardiomyopathy have been determined since 1989. (nih.gov)
More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
Thus, stress response studies during these growth stages reveal novel differentially regulated genes or proteins with important functions in plant stress adaptation. (intechopen.com)
Most of these GC-balanced genes encode Cryptosporidium-specific proteins that have intrinsically disordered regions and are involved in host-parasite interactions. (cdc.gov)

These results suggest that cell transformation induced by Cd may be attributed, at least in part, to gene amplification of c-myc and c-jun and that some of the Cd-transformed cells may possess neoplastic potential resulting from genomic instability. (cdc.gov)
Functional gene diversity in the gabbroic samples was analyzed with a microarray for metabolic genes ("GeoChip"), producing further evidence of genomic potential for hydrocarbon degradation - genes for aerobic methane and toluene oxidation. (figshare.com)

Thirty SNPs of well-defined functional genes were investigated. (cancerindex.org)
Two SNPs in X-Ray Repair Cross Complementing 2 gene (XRCC2) rs2040639 and interferon gamma (IFNG) rs2069705 genes were found to be associated with ARSR. (cancerindex.org)
We performed a case-control study to investigate the association between the two SNPs in the MTHFR gene and risk of breast cancer. (medsci.org)
Polymorphisms including single nucleotide polymorphisms (SNPs) in genes involved in xenobiotic metabolism and in genes involved in oestrogen biosynthesis and metabolism might affect circulating estrogen levels and modulate the individual susceptibility to environmental carcinogens in relation to developing BC [ 5 ]. (biomedcentral.com)

Gene sequences from normal and carrier animals were compared using the software, codon code Aligner 4.0.4. (researchgate.net)
DNA sequence analysis of the 3′-end of the Coagulase ( coa ) gene revealed heterogeneity in the 81 bp tandem repeats region that encoding repeated 27-amino-acid sequences in the C-terminal region. (hindawi.com)
Considering the current limitations of NGS technology, full-length 16S rRNA gene sequences are better suited to downstream analytical methods such as fluorescence in situ hybridization. (frontiersin.org)
The original designs of most of the PCR primers used for the analysis of 16S rRNA genes were based on known sequences deposited in public databases. (frontiersin.org)
For example, a complete 16S rRNA gene sequence can be obtained by analyzing the sequences of genomes or large genome fragments, providing taxonomic information along with information on other functional genes. (frontiersin.org)
In total, 72.61% of the AlkB sequences were related to Gammaproteobacteria, including Alcanivorax and Marinobacter , while the SDIMO genes were similar to Phenol-2 , Mmo , ThmA , PmoC and PrmA genes, with 72% of the sequences found being novel. (int-res.com)
The coding sequences of the hepatitis B virus surface antigen were inserted into a baculovirus transfer vector produced from Autographa califomica nuclear polyhedrosis virus (AcNPV) so that the foreign gene was under the control of the AcNPV polyhedrin promoter. (microbiologyresearch.org)
The nucleotide sequences of Serine-Rich Entamoeba histolytica Protein (SREHP) gene have already exhibited stable and significant polymorphism in the gene studies. (scialert.net)
The first nucleotide sequences have been shown the stable and significant polymorphism in the Strain Specific Gene (SSG) and the Serine-Rich E. histolytica Protein (SREHP) gene. (scialert.net)

In this study, we analyzed the allele and genotype frequencies of the urotensin-II gene ( UTS2 ) polymorphisms, Thr21Met and Ser89Asn, among Turkish patients with migraine. (bjbms.org)
No significant differences were observed in allele and genotype frequencies for Thr21Met and Ser89Asn polymorphisms between the patients with migraine and control group. (bjbms.org)

Methods: This case-control study conducted in Srinagar, Kashmir (North India) between 2013 and 2015 was designed to evaluate risk induced due to MTH-FR 677C>T gene polymorphisms to contribute in susceptibility for migraine in Kashmir population (North India). (scirp.org)
Two common polymorphisms in the MTHFR gene, C677T and A1298C, are associated with reduced enzyme activity and may be associated with breast cancer susceptibility. (medsci.org)
Results Our results suggest that, in the Thai population, polymorphisms in XRCC1 and OGG1 genes, particularly in combination, are associated with increased susceptibility to CCA, and that their role as modifiers of the effect of smoking and alcohol consumption influences the risk of CCA. (bmj.com)
Aim: Accumulating evidence suggests that DNA damage and repair play a role in asthma etiology, however, little is known about the contribution of genotypes of DNA repair genes to asthma susceptibility. (iiarjournals.org)

It is caused by a point mutation (G→T) at nucleotide position 559 of the gene, bovine solute carrier family 35 member 3 (SLC35A3). (researchgate.net)
In this study, amplification, expression, and point mutation of cancer-related genes associated with Cd-induced cell transformation in BALB/c-3T3 cells were studied. (cdc.gov)
Chorionic villus biopsy at 8 weeks gestation on amniocentesis at 12-14 weeks can be used for prenatal diagnosis by DNA analysis if the mother's carrier state is demonstrated either by mutation analysis or Restriction Fragment Length polymorphism study. (pediatriconcall.com)
The present case-control study aimed to investigate the main effect of polymorphisms in genes involved in xenobiotic metabolism and estrogen biosynthesis, CYP1A1, CYP1B1, COMT and CYP17, CYP19 and the BRCA1 founder mutation in relation to BC risk and to explore possible interactions between the gene polymorphisms and serum POP levels on BC risk in Greenlandic Inuit women. (biomedcentral.com)
The BRCA1 founder mutation and polymorphisms in CYP1A1 (Val) and CYP17 (A1) can increase the BC risk among Inuit women and the risk increases with higher serum levels of PFOS and PFOA. (biomedcentral.com)
When the specific FIX gene mutation is known, direct genetic testing provides accurate results. (medscape.com)

No significant differences were found in the genotypes of the two polymorphisms of the MTHFR gene between cases and controls. (medsci.org)
There was a highly significant (P ≤ 0.01) association between the single nucleotide polymorphism (SNP) and reproductive traits, in that sheep with the p.K116Q SNP had lower litter size, twinning rate, fecundity, and lambing percentages than individuals with CC genotypes. (researchsquare.com)
In Clark and Diamond (1993) study, 16 different genotypes were observed among 18 isolates of E. histolytica from diverse geographical locations using the combined results of restriction digestion of SREHP and amplification of the SSG locus. (scialert.net)
This study aimed to examine the contribution of genotypes of DNA double-strand break repair gene X-ray repair cross complementing protein 3 (XRCC3) and its polymorphisms to asthma risk in the Taiwanese. (iiarjournals.org)

Heterogeneity of Porphyromonas gingivalis strains on fimbrillin gene locus by restriction fragment length polymorphism analysis. (bvsalud.org)

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. (wikipedia.org)
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. (cancerindex.org)
What does this gene/protein do? (cancerindex.org)
Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
This gene encodes OLR1 protein and belongs to the C-type lectin family that functions to absorb and degrade low-density lipoproteins [5], which impacts energy balance, in turn influencing reproductive characteristics [3]. (researchsquare.com)
It is also possible that this encoded protein functions to regulate fecundity genes so that the OLR1 gene is involved in sheep fecundity [2]. (researchsquare.com)
The coding region of the carboxy- terminal half of polyhedrin was removed and the remainder was ligated with the IGF II gene in phase to create a fusion protein gene consisting of the coding region of the amino-terminal half of polyhedrin and the IGF II gene. (microbiologyresearch.org)
This fusion protein gene was combined in a plasmid with the promoter and 5′ and 3′ flanking regions of the polyhedrin gene. (microbiologyresearch.org)
Genetic diversity of Iranian E. dispar isolates based on the SREDP was more polymorphic in comparison of Serine-Rich Entamoeba histolytica Protein (SREHP) of the E. histolytica isolates as well as were different from a few known SREDP genes. (scialert.net)
7 Primers designed to amplify the partial groEL gene encoding heat-shock protein of Anaplasma phagocytophilum EphplgroELF (5′-ATGGTATGCAGTTTGATCGC-3′) and EphplgroELR (5′-TCTACTCTGTCTTTGCGTTC-3′) were used and expected to yield a 625-bp product for Anaplasma phagocytophilum and for Anaplasma platys , respectively. (who.int)
In agreement with this, the fox-derived isolate possesses more subtelomeric genes encoding invasion-related protein families. (cdc.gov)

Disease causing variants of the ATP1A3 gene are known to cause a variety of movement disorders and epilepsies. (wikipedia.org)
The results have demonstrated that many new variants of the coa gene are present in Minia, Egypt, different from those reported in the previous studies. (hindawi.com)
Apolipoprotein E (APOE) gene variants have been reported to influence psoriasis risk. (hindawi.com)
Inheritance being multifactorial, genetic variants in multiple genes interact both with each other and with the environment [ 13 - 20 ]. (hindawi.com)
We investigated a panel of 34 known high/moderate-risk cancer genes, including 16 related to breast or ovarian cancer (BC/OC) genes, and 63 candidate genes to BC/OC in 192 clinically suspicious of hereditary breast/ovarian cancer (HBOC) Spanish families without pathogenic variants in BRCA1 or BRCA2 (BRCA1/2). (cancerindex.org)
For analysis the genetic diversity of the sub allelic variants of Pvmsp3α and Pvmsp3β genes, Chi-Square test was performed by utilizing Minitab programming software 18. (scielo.br)

Rickettsia conorii restriction profile corresponding to Molecular analysis of spotted has been thought to be the only path- that of R. conorii strain Seven. (cdc.gov)
Single-strand conformation polymorphism analysis was used to search for mutations in the coding segments of the MYL2 gene, and the abnormal products were sequenced. (nih.gov)
By analysis of genetic recombinations, one of these mutations identified in a large family allowed us to refine the localization of the MYL2 gene on the genetic map, in an interval of 6 cM containing six informative microsatellite markers. (nih.gov)
In conclusion, we show that mutations in the MYL2 gene may be involved in familial and classical forms of hypertrophic cardiomyopathy, and we provide new tools for the genetic analysis of patients with familial hypertrophic cardiomyopathy. (nih.gov)
Blood-based single nucleotide polymorphism (SNP) analysis was performed. (cancerindex.org)
Point mutations in K-ras and p53 were studied by PCR restriction fragment length polymorphism analysis and DNA sequencing. (cdc.gov)
Polymorphisms in BER genes were analysed using a PCR with high-resolution melting analysis. (bmj.com)
Moreover, the haplotype analysis showed no association between UTS2 gene haplotypes (MN, MS, TN, and TS) and migraine. (bjbms.org)
During the Integrated Ocean Drilling Program Expeditions 304 and 305, igneous rock samples were collected from 0.45-1391.01 meters below seafloor at Hole 1309D, located on the Atlantis Massif (30 °N, 42 °W). Microbial diversity in the rocks was analyzed by denaturing gradient gel electrophoresis and sequencing (Expedition 304), and terminal restriction fragment length polymorphism, cloning and sequencing, and functional gene microarray analysis (Expedition 305). (figshare.com)
Here, we further tested this hypothesis by using available data from 41 whole genomes to characterize sub-assemblages and coalescent techniques for statistical estimation of species boundaries coupled to functional gene content analysis, thereby assessing the stability and distinctiveness of clades. (cdc.gov)
Our analysis revealed two new sub-assemblage clades as well as novel signatures of gene content geared toward differential host adaptation and population structuring via vertical inheritance rather than recombination or panmixia. (cdc.gov)

PCR amplification of this region showed DNA bands of different size and number that could be further differentiated by using restriction enzyme AluI [ 10 ]. (hindawi.com)
Among 10 Cd-induced transformed cell lines, significant gene amplification was found for c-myc and c-jun in 50% and 80% of the cell lines, respectively. (cdc.gov)
High- fidelity mRNA amplification for gene profiling. (genomicglossaries.com)

This was explored using 16S rRNA gene-based terminal restriction fragment length polymorphism, along with alkane hydroxylase (AlkB) and soluble di-iron monooxygenase (SDIMO) gene-based clone libraries. (int-res.com)
β-diversity at the phylum/class level (class level for Proteobacteria ) and terminal restriction fragment (T-RF) level responded differently to the abiotic factors. (int-res.com)

Dopamine receptor D2 gene polymorphism, urine fluoride, and intelligence impairment of children in China: A school-based cross-sectional study. (fluoridealert.org)

Coagulase gene PCR-RFLPs exhibited 10 patterns that ranged from 1 to 8 fragments with AluI digestion. (hindawi.com)
Segments of DNA called restriction fragment length polymorphisms (RFLPs) are the objectives of the tests with gene probes. (cliffsnotes.com)
RFLPs are apparently useless bits of DNA located near genes associated with the diseases. (cliffsnotes.com)
By locating RFLPs, the biotechnologist can locate the disease gene. (cliffsnotes.com)

Conclusions: We conclude that MTHFR gene C677T polymorphism has no role in predisposition to the migraine in our population and cannot serve as a predictive factor for the risk of migraine. (scirp.org)
Furthermore, it has been shown in patients with breast cancer a risk of presenting with an aggressive biophenotype about twice or three times higher in the presence of the C677T and A1298C polymorphisms, respectively. (medsci.org)

Sheep's fecundity is determined by both twinning rate and litter size, both influenced by several genes, one of which is OLR1 (oxidized low-density lipoprotein receptor gene). (researchsquare.com)

A number of markers are now available to detect nuclear DNA polymorphisms. (intechopen.com)

This gene encodes an alpha 3 subunit. (wikipedia.org)

The aim of the present study was to search for mutations in the ventricular regulatory myosin light chain gene (MYL2), located on chromosome 12q23q24.3, in a panel of 42 probands presenting a classical phenotype of familial hypertrophic cardiomyopathy. (nih.gov)
Both are inherited as a sex-linked recessive disorder as the genes responsible for factor VIII & IX are located on the X chromosome. (pediatriconcall.com)
Females are usually carriers as they have two X-chromosome and can pass on the defective gene to her offspring. (pediatriconcall.com)
OTC is coded on band p21.1 of the X chromosome, where the gene contains 8 exons and spans 85 kb of DNA. (nih.gov)
This enzyme is coded on human chromosome 9, where a 63-kb gene comprising 14 exons is located. (nih.gov)
The results showed that, in all the strains examined, ure and trh were detected on the same Not I fragment, showing that the two genes localise within a relatively small portion of the chromosome DNA. (microbiologyresearch.org)
Any method used for determining the location of and relative distances between genes on a chromosome. (bvsalud.org)
Chronic Myeloid Leukemia (CML) is associated with translocation between chromosome 9 & chromosome 22, t(9;22)(q34;q11.2) and with the formation of BCR-ABL fusion gene. (who.int)

The rpoB gene target sequence was amplified using mutagenesis forward and reverse primers followed by HindIII enzyme digestion. (who.int)

This region contains a candidate tumor suppressor gene, TP53, which has recently been implicated in the etiology of a broad array of human cancers. (nih.gov)

The catalytic subunit of Na+/K+-ATPase is encoded by multiple genes. (wikipedia.org)

To the our best of knowledge, this is the first study to report the existence of homozygous and heterozygous mutations at positions 554, 555 and 559 in exon 4 of SLC35A3 gene in Indian Holstein cattle. (researchgate.net)
Five of the 11 grade III astrocytomas (glioblastoma multiforme), but only one of seven grade II astrocytomas (anaplastic astrocytoma) and none of either the grade I astrocytomas or oligodendrogliomas demonstrated distinct point mutations involving the TP53 gene. (nih.gov)
Comparative gene mapping among human, murine, and canine genomes have the potential to rapidly identify mutations that underlie various disease syndromes. (stanford.edu)

MicroRNAs have been reported to regulate about one-third of human genes [ 11 ] . (researchsquare.com)

Despite the fact that the latest NGS technologies enable reading only of relatively short sequence fragments (~500 bp), these so-called "deep sequencing" methods are still powerful tools that ultimately may enable researchers to obtain a more holistic understanding of microbial communities in their natural environments ( Fuhrman, 2009 ). (frontiersin.org)
This method can generate tens of billions of copies of a particular DNA fragment (the sequence of interest, DNA of interest, or target DNA) from a DNA extract (DNA template). (intechopen.com)
Using DNA extracted from bacteria in the dental plaque of mother/child pairs, a sequence of the S. mutans spaP gene was amplified using PCR. (bvsalud.org)

Sodium/potassium-transporting ATPase subunit alpha-3 is an enzyme that in humans is encoded by the ATP1A3 gene. (wikipedia.org)
This may be due to the loss of intestinal lactase in adulthood, a condition transmitted by an autosomal recessive gene, which differs in humans according to race. (researchgate.net)
A biological process that is crucial for gene expression in most animal life, including humans. (genomicglossaries.com)

they used a nested PCR of the SREHP gene coupled with restriction digestion. (scialert.net)

Our study has not shown a significant association between MTHFR gene polymorphisms and breast cancer risk. (medsci.org)

The current study aimed to use Coagulase gene polymorphism to identify methicillin-resistant Staphylococcus aureus (MRSA) subtypes isolated from nasal carriers in Minia governorate, Egypt, evaluate the efficiency of these methods in discriminating variable strains, and compare these subtypes with antibiotypes. (hindawi.com)
The aim of this study was to use coa gene polymorphism to identify MRSA subtypes isolated from nasal carriers in Minia governorate, Upper Egypt, evaluate the efficiency of these typing methods in discriminating variable strains, and compare these subtypes with antibiotypes. (hindawi.com)
Considering the coincidence between production of urease and possession of trh in V. parahaemolyticus , it was concluded that the presence or absence of the ure gene is completely coincident with that of the trh gene in V. parahaemolyticus strains. (microbiologyresearch.org)
These results suggest that the ure and trh genes are genetically linked in V. parahaemolyticus strains. (microbiologyresearch.org)

Length Polymorphism (PCR-PIRA and RF LP) methods. (researchgate.net)

Direct evidence for the presence of these viruses in human genital tumours is the finding that a small proportion (about 10%) retain fragments of virus DNA from different regions of the virus genomes. (microbiologyresearch.org)
While the genomes of C. canis have similar gene contents and organisations, they (~41.0%) and C. felis (39.6%) have GC content much higher than other Cryptosporidium spp. (cdc.gov)

A total of 146 patients with migraine (14 with aura [MA group] and 132 without aura [MO group]) were genotyped for Thr21Met and Ser89Asn polymorphisms and compared with 154 age- and sex-matched healthy controls. (bjbms.org)
In summary, Thr21Met and Ser89Asn polymorphisms of the UTS2 gene are not risk factors for migraine in our sample of Turkish migraine patients. (bjbms.org)
Pour identifier les espèces de Leishmania , des techniques moléculaires ont été appliquées sur des échantillons prélevés chez 64 patients atteints de leishmaniose cutanée orientés vers l'hôpital régional d'Herat en 2013. (who.int)
L'objectif de ce travail était de décrire le profi l des manifestations cardiovasculaires chez les patients vivants avec le VIH en le comparant à celui de patients séronégatifs. (bvsalud.org)

Endothelial nitric oxide synthase ( eNOS) gene polymorphism may influence the response to salbutamol in healthy subjects. (ijp-online.com)

however, the possible mechanism of carcinogenesis with regards to the activation and inactivation of cancer-related genes has not yet been fully elucidated. (cdc.gov)
Regulation of single nucleotide polymorphisms (SNP) in micro-RNA (miRNA) on the host cells may be one of the most important factors influencing the occurrence of cervical cancer based on the prevalence of HPV infection and the development of cervical cancer. (researchsquare.com)
In order to explore the contribution of miRNA polymorphism to the occurrence and development of cervical cancer, we conducted an analytical study. (researchsquare.com)
Therefore, they may be two gene regulatory points for the prevention of cervical cancer. (researchsquare.com)

presents an opportunity to manipulate gene expression within the cells to treat various diseases, and acts as a powerful tool for studying gene function utilizing antisense agents to manage the diseases by regulating the expression of the specific factor that actually causes the particular disease. (genomicglossaries.com)
Many diseases have been found to be related to genes. (researchsquare.com)

This study aimed to determine the genetic variation of the OLR1 gene affecting the fecundity traits of Awassi ewes. (researchsquare.com)
The present study attempted to identify the gene ure encoding urease in V. parahaemolyticus to clarify the relationship between urease production and possession of trh. (microbiologyresearch.org)

MicroRNAs (miRNAs) are a class of non-coding single-stranded RNA molecules with a length of about 22 nucleotides that regulate various intracellular activities such as cell proliferation, apoptosis and carcinogenesis [ 8 - 10 ] . (researchsquare.com)

Our results show that one out of 60 bulls tested exhibited polymorphism (G→T) at position 559 in exon 4 of SLC35A3 gene. (researchgate.net)

Objective: To detect the presence and transmission of S. mutans carrier of the spaP gene in samples of bacterial plaque in mother/child pairs from municipal child education centers, and the possible association with dental caries. (bvsalud.org)

We therefore examined whether polymorphisms in DNA base-excision repair (BER) genes, XRCC1 G399A and OGG1 C326G, were associated with CCA risk and whether they modified the effect of smoking and alcohol drinking in the Thai population. (bmj.com)

554, 555 and 559 in exon 4 of SLC35A3 gene in Indian Holstein cattle. (researchgate.net)
The A/C SNP in the 3′-UTR fragment of the OLR1 gene has been linked to lactational traits in Iranian Holstein cattle [15]. (researchsquare.com)

A DNA probe is a relatively small, single-stranded fragment of DNA that recognizes and binds to a complementary section of DNA on a larger DNA molecule. (cliffsnotes.com)

Each miRNA can have multiple target genes, and several miRNAs can regulate the same gene. (researchsquare.com)

exon 4 of SLC35A3 gene. (researchgate.net)
An SNP within the exon and intron regions of the OLR1 gene is associated with phenotypic traits in cattle, according to Komisarek and Dorynek [6] and Fonseca et al . (researchsquare.com)

To investigate the gene frequency of the T235 allele and its relationship with hypertension in two Japanese populations. (lww.com)

14] provided evidence of the association between the polymorphisms of the OLR1 gene and growth traits, as well as dairy quality parameters in buffalo. (researchsquare.com)
Considering the aforementioned studies, there has been little research conducted on the impact of genetic polymorphisms in the OLR1 gene on fecundity traits in livestock, and no research on their association with fecundity traits in Awassi sheep. (researchsquare.com)
An association was found between experience of caries in the children and the presence of bacteria carrying the spaP+ gene. (bvsalud.org)

Cloning and characterization of SREHP gene from an Iranian E. histolytica isolate was also studied (Rasti et al . (scialert.net)

Anatomy7

Organisms21

Diseases10

Chemicals and Drugs66

Analytical, Diagnostic and Therapeutic Techniques and Equipment49

Psychiatry and Psychology1

Phenomena and Processes84

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Information Science5

Named Groups4

Health Care28

Geographicals19

Polymerase14

RFLP11

Proteins4

Genomic2

SNPs4

Sequences9

Genotype2

Susceptibility4

Mutation6

Genotypes4

Locus1

Protein12

Variants6

Analysis11

Amplification3

Terminal restriction2

Dopamine1

RFLPs4

C677T2

Receptor gene1

Markers1

Encodes1

Chromosome8

Primers1

Tumor Suppressor1

Multiple genes1

Mutations3

Human genes1

Sequence3

Humans3

Digestion1

MTHFR1

Strains4

Methods1

Genomes2

Patients4

Endothelial1

Cancer4

Diseases2

Study2

Carcinogenesis1

Results1

Detect1

Risk1

Holstein2

Relatively small1

Regulate1

Exon2

Frequency1

Association3

Isolate1