Loading...
  • SNPs
  • In single-SNP association tests, the SNPs rs11647932, rs11645214, and rs6499323 located at 16q22.1 under the additive-effect disease model were significantly associated with an approximately 2-fold increased risk of DN. (biomedcentral.com)
  • To conclude, these results indicate that SNPs in the OPG gene may be implicated in the pathogenesis of DR. (hindawi.com)
  • atherosclerosis
  • Increased aortic intima-media thickness: a marker of preclinical atherosclerosis in high-risk children," Circulation , vol. 104, no. 24, pp. 2943-2947, 2001. (hindawi.com)
  • Furthermore, diabetic patients (especially women) carry a significantly greater cardiovascular risk than nondiabetic individuals ( 20 ), and even subtle disturbances in glucose metabolism appear to be linked with premature atherosclerosis ( 21 , 22 ). (diabetesjournals.org)
  • Bone
  • Evaluation of the role of RANK and OPG genes in Paget's disease of bone," Bone , vol. 28, no. 1, pp. 104-107, 2001. (hindawi.com)
  • protein
  • The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. (abnova.com)
  • DNA sequence analysis of inherited cataract families showed 72 nucleotide variations, of which 15 were observed in the major non-coding D-loop region, 3 in the tRNA genes, 5 in the rRNA genes, and 49 in the protein coding region. (molvis.org)
  • Mutations in various genes have been reported to be associated with various phenotypes and they include crystallins, connexins, aquaporin, beaded structural filament protein 2, transcription factors like paired-like homeodomain 3 ( PITX3 ) and heat shock transcription factor 4 ( HSF4 ), avian musculoaponeurotic fibrosarcoma ( MAF ) protein and chromosome modifying proteins. (molvis.org)
  • allele
  • respectively), and a significant interactive effect between these factors was found on the risk of a high baPWV and DR. The HDL-C level at baseline was a significant predictor of a high baPWV only in G allele carriers according to the ROC analysis. (biomedcentral.com)
  • factors
  • investigated the clinical factors associated with retinal detachment (RD) after open-globe trauma and developed a forecasting model for physicians to use when assessing patients' risk. (aao.org)
  • The determination of the risk of vascular events using this risk engine should be estimated at diagnosis and recalculated during subsequent years in order to ensure that optimized treatment of vascular risk factors is achieved. (rcsi.ie)
  • It can occur even in normonatremic patients, especially who have risk factors like alcoholism, malnutrition and liver disease. (readbyqxmd.com)
  • Invasive pulmonary disease due to the moldAspergillus fumigatuscan be life-threatening in lung transplant recipients, but the risk factors remain poorly understood. (stanford.edu)
  • enzyme
  • The polymorphisms were detected by Polymerase Chain Reaction (PCR) and appropriate restriction enzyme digestion (HpyCH4III, SFANI, respectively). (openarchives.gr)
  • Functional polymorphisms in the CYP2D6 gene may affect enzyme activity and thus, the metabolism of donepezil. (biomedsearch.com)
  • The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. (abnova.com)
  • factor
  • Various neuroimaging techniques, in particular positron emission topography (PET) and magnetic resonance imaging (MRI), have been instrumental in characterizing these metabolic and vascular deficits associated with this important AD risk factor. (frontiersin.org)
  • CONCLUSIONS -Hp phenotype is an apparent risk factor for the development of GDM in our study population. (diabetesjournals.org)
  • Treatment
  • Polymorphisms of Interleukins, Glypican, and Human Leukocyte Antigen Genes and Treatment Response in Multiple Sclerosis. (clinicaltrials.gov)
  • These authors took endo- metrial aim biopsies in the forefront and after government of continuous combined hormone replacement remedy and reported that long-term treatment of daily 2 mg estradiol and 1 mg norethisterone acetate into up to 5 years did not flourish the risk of endometrial hyperplasia nor malignancy. (wgc2010.sk)
  • Esmon CT Does angiopathy encourage to thrombotic events [url=http://meritcontractorsinc.com/session/dir3/position11/]50mg avana amex[/url] best erectile dysfunction pills treatment. (wgc2010.sk)
  • found
  • Nicotinamide adenine dinucleotide dehydrogenase (NADH) subunit ( ND ) gene of mtDNA was highly altered, in general, and found to contain 4 variations specific for cataract patients of the first family, six for the second, and one for the third family. (molvis.org)
  • The gene is found in a cluster of three related paraoxonase genes at 7q21.3. (abnova.com)
  • Subjects
  • In this work a number of strategies have been discussed whereby subjects with increased CVD risk could be identified earlier and targeted for particularly aggressive interventions. (rcsi.ie)