• Gene Expression Regulation, Neoplastic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • This graph shows the total number of publications written about "Gene Expression Regulation, Neoplastic" by people in this website by year, and whether "Gene Expression Regulation, Neoplastic" was a major or minor topic of these publications. (uchicago.edu)
  • Below are the most recent publications written about "Gene Expression Regulation, Neoplastic" by people in Profiles. (uchicago.edu)
  • Some genes are responsible for the production of other forms of RNA that play a role in translation, including transfer RNA (tRNA) and ribosomal RNA (rRNA). (le.ac.uk)
  • It is these portions of the gene that are represented in final mature mRNA molecule. (le.ac.uk)
  • Introns are portions of the gene that do not code for amino acids, and are removed (spliced) from the mRNA molecule before translation. (le.ac.uk)
  • It is not transcribed into mRNA, but plays a role in controlling the transcription of the gene. (le.ac.uk)
  • The present study discovered a new regulatory principle for controlling gene expression that targets the so-called messenger RNA (mRNA), which is a copy of the genomic information that serves as a template for protein synthesis. (au.dk)
  • MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program. (duke.edu)
  • Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal center B-cell (GCB)-like and unfavorable activated B-cell (ABC)-like subtypes based on gene expression signatures. (duke.edu)
  • It was found that the gene regulation in B. atrophaeus UCMB-5137 in response to the root exudate stimuli differed from the reported gene regulation at similar conditions in B. amyloliquefaciens FZB42, which was considered as a paradigm PGPR. (up.ac.za)
  • This difference was explained by hypersensitivity of UCMB-5137 to the root exudate stimuli impelling it to a sessile root colonization behavior through the CcpA-CodY-AbrB regulation. (up.ac.za)
  • Endocrine disruption in human placenta: expression of the dioxin-inducible enzyme, CYP1A1, is correlated with that of thyroid hormone-regulated genes. (umassmed.edu)
  • Combining the simplicity of CRISPR/Cas9 targeting-free from DNA cleavage activity-with inducible and reversible protein dimerization partners, the CLOuD9 Gene Expression Regulation Kit adds a new dimension to your gene regulation studies. (systembio.com)
  • Learn how genes can be turned 'on' and 'off' and why this is essential for cellular function. (bandstemmen.info)
  • In multicellular organisms, gene regulation drives cellular differentiation and morphogenesis in the embryo, leading to the creation of different cell types that possess different gene expression profiles from the same genome sequence. (wikipedia.org)
  • Hao H, Aixia Y, Dan L, Lei F, Nancai Y, Wen S. Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. (labome.org)
  • 3(high) CD4(+)CCR7(-) T cell selectivity through two different pathways, including the classic channel activity-associated IL-2 pathway and the new Kv1.3 channel gene expression pathway. (labome.org)
  • Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F. (reactome.org)
  • In the present study, we analyzed the expression of the BCL2-family genes across 10 mature B cell malignancies through computational normalization of 21 publicly available Affimetrix datasets gathering 1,219 patient samples. (frontiersin.org)
  • To better understand the deregulation of anti- and pro-apoptotic members of the BCL2-family in hematological disorders, we first compared gene expression profiles of malignant B cells to their relative normal control (naïve B cell to plasma cells, n = 37). (frontiersin.org)
  • Finally, by integrating recent data on venetoclax-monotherapy clinical activity with the expression of BCL2-family members involved in the venetoclax response, we determined that the ratio (BCL2 + BCL2L11 + BAX)/BCL2L1 was the strongest predictor of venetoclax response for mature B cell malignancies in vivo . (frontiersin.org)
  • Gene expression is the process by which the genetic code - the nucleotide sequence - of a gene is used to direct protein synthesis and produce the structures of the cell. (le.ac.uk)
  • How does a cell know which genes to express and when? (bandstemmen.info)
  • The Centre aims to enhance our understanding of how genes are regulated at both the single cell and whole organism level. (wikipedia.org)
  • Polymorphisms in the kinesin-like factor 1 B gene and risk of epithelial ovarian cancer in Eastern Chinese women. (duke.edu)
  • BCL2-family proteins have a central role in the mitochondrial apoptosis machinery and their expression is known to be deregulated in many cancer types. (frontiersin.org)
  • Across all cancer types, we showed that anti-apoptotic genes are upregulated while pro-apoptotic genes are downregulated when compared to normal counterpart cells. (frontiersin.org)
  • Ren L, Deng B, Saloura V, Park JH, Nakamura Y. MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells. (uchicago.edu)
  • A region a few hundred nucleotides 'upstream' of the gene (toward the 5' end). (le.ac.uk)
  • The kinesin-like factor 1 B (KIF1B) gene plays an important role in the process of apoptosis and the transformation and progression of malignant cells. (duke.edu)
  • Restoration of the expression of transports associated with antigen processing in human malignant melanoma increases tumor-specific immunity. (labome.org)
  • Of interest, our analysis highlighted that, independently of the nature of malignant B cells, the pro-apoptotic BH3-only BCL2L11 and PMAIP1 are deeply repressed in tumor niches, suggesting a central role of the microenvironment in their regulation. (frontiersin.org)
  • Omman RA, Speiser J, Robinson S, Lapadat R, Mudaliar K. Clonal highlights: Clonal seborrheic keratoses often demonstrates p16 expression. (uchicago.edu)
  • Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis. (umassmed.edu)
  • Zhou X, Feng H, Guo Q, Dai H. Identification and characterization of the first reptilian CD9, and its expression analysis in response to bacterial infection. (labome.org)
  • Hyperacute Monocyte Gene Response Patterns Are Associated With Lower Extremity Vein Bypass Graft Failure. (ouhsc.edu)