Ubiquitin-Protein LigasesUbiquitinLigasesUbiquitinsUbiquitin-Conjugating EnzymesAngelman SyndromeUbiquitinationUbiquitin-Protein Ligase ComplexesEndosomal Sorting Complexes Required for TransportProteasome Endopeptidase ComplexCullin ProteinsAnaphase-Promoting Complex-CyclosomeSKP Cullin F-Box Protein LigasesMolecular Sequence DataAmino Acid SequenceCarbon-Nitrogen LigasesProtein BindingPolyubiquitinF-Box ProteinsUbiquitin ThiolesteraseMutationUbiquitin-Activating EnzymesS-Phase Kinase-Associated ProteinsFatty Acid Synthase, Type IIBiotinylationSubstrate SpecificityRNA Ligase (ATP)Protein Structure, TertiarySaccharomyces cerevisiae ProteinsProteolysisbeta-Transducin Repeat-Containing ProteinsCell Cycle ProteinsCell LineSaccharomyces cerevisiaeSequence Homology, Amino AcidPeptide SynthasesBiotinF-Box MotifsCysteine EndopeptidasesMultienzyme ComplexesCarrier ProteinsProtein Processing, Post-TranslationalHeLa CellsThioctic AcidRING Finger DomainsUbiquitin CRecombinant Fusion ProteinsRepressor ProteinsMultiprotein ComplexesBase SequenceHEK293 CellsAcetyl-CoA CarboxylaseVon Hippel-Lindau Tumor Suppressor ProteinDNA LigasesHydroxyapatitesProteinsTranscription FactorsInhibitor of Apoptosis ProteinsTwo-Hybrid System TechniquesAmino Acid MotifsAdenovirus E4 ProteinsProtein StabilityModels, MolecularDNA-Binding ProteinsNuclear ProteinsImmunoprecipitationProto-Oncogene Proteins c-cblUbiquitinated ProteinsSignal TransductionLysineRecombinant ProteinsPolynucleotide LigasesUbiquitin-Specific ProteasesRNA InterferenceProtein TransportModels, BiologicalAdaptor Proteins, Signal TransducingSUMO-1 ProteinPeptide HydrolasesRNA, Small InterferingEscherichia coliCell Line, TumorTumor Suppressor ProteinsProteasome InhibitorsIntracellular Signaling Peptides and Proteinsvif Gene Products, Human Immunodeficiency VirusCyclin-Dependent Kinase Inhibitor ProteinsCarbon-Nitrogen LyasesBinding SitesPhosphorylationEndopeptidasesBacterial ProteinsCell CycleSmall Ubiquitin-Related Modifier ProteinsLeupeptinsTransfectionImmunoblottingCloning, MolecularSumoylationProto-Oncogene Proteins c-mdm2