AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesTechnology, Industry, AgricultureInformation Science
CarboxylesteraseCarboxylic Ester HydrolasesParaoxonProdrugsEsterasesHydrolysisPhenylmethylsulfonyl FluorideIsoflurophateCamptothecinPalmitoyl-CoA HydrolaseNitrophenolsMalathionCaprolactamMicrosomes, LiverMolecular Sequence DataPhenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) EsterPyrethrinsUmbelliferonesAntineoplastic Agents, PhytogenicChemical Warfare AgentsInsecticide ResistanceSubstrate SpecificityOrganophosphatesNaphthaleneacetic AcidsSomanButyrylcholinesteraseAmino Acid SequenceAcetyl-CoA HydrolaseChlorpyrifosAlicyclobacillusUrethaneEstersLiverCloning, MolecularMonoacylglycerol LipasesCholinesterase InhibitorsCholatesBiotransformationInsecticidesSequence Homology, Amino AcidHydroxymercuribenzoatesLoperamideOchrobactrum anthropiAcetylcholinesteraseBase SequenceOrganophosphorus Compounds
EnzymeResponsible for the hydrolysisProtein kinaseMicroarrayProteins involvedOrthologResistance genesEnzymesGenomicExpressionHumansVariantsGenomeSynthesisReductaseTissuesAnalysesCharacterizationSymbolTranscriptomicRicePlantFamilySequencesProstateActivityMousePreviouslyShowNumerousMultiplePopulation
Enzyme9
  • Carboxylesterase 3 is an enzyme that in humans is encoded by the CES3 gene. (wikipedia.org)
  • From NCBI Gene: This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. (nih.gov)
  • The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. (nih.gov)
  • It encodes a secreted enzyme. (utsouthwestern.edu)
  • Because of high levels in the urine of male domestic cats, this enzyme is also called cauxin (carboxylesterase-like urinary excreted protein). (utsouthwestern.edu)
  • Transcriptomic analysis revealed the exclusive expression of 10 genes encoding five distinct enzyme classes in a high noscapine-producing poppy variety, HN1. (ampliconexpress.com)
  • In contrast a number of other functionally characterized genes associated with benzylisoquinoline alkaloid synthesis, including Berberine Bridge Enzyme ( BBE ), Tetrahydroprotoberberine cis-N-MethylTransferase ( TNMT ), Salutaridine Reductase ( SalR ), Salutaridinol 7-O-AcetylTransferase ( SalAT ) and Thebaine 6-O-demethylase ( T6ODM ) were expressed in all three varieties ( Fig. 1B ). (ampliconexpress.com)
  • Converted by the carboxylesterase enzyme to its active metabolite from, SN-38. (medscape.com)
  • Biochemistry bioassays confirmed the involvement of monooxygenase enzyme, carboxylesterase, superoxide dismutase and peroxidase in multi-insecticide resistance mechanism. (preprints.org)
Responsible for the hydrolysis2
  • The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. (wikipedia.org)
  • The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. (utsouthwestern.edu)
Protein kinase1
  • Ten genes were transcriptionally induced exclusively by the BP178 therapy, and seven of them is usually mapped and identified as pathogenesis-related protein1, glycosidase, a member of ABC transporter loved ones, ser/thr protein kinase, cold shock protein (chaperone), pre-mRNAsplicing issue CLF1, and CXE carboxylesterase. (atminhibitor.com)
Microarray3
  • These candidate genes have been selected amongst genes showing considerable induction profiles within the preceding microarray evaluation of Solanum lycopersicum, which encode proteins involved in plant-defense mechanisms (Supplementary Table 1) or with no considerable alterations in expression following the remedies. (atminhibitor.com)
  • The microarray fabricated based on the EST information will be useful for finding genes related to agricultural and biological problems related to this pest. (biomedcentral.com)
  • The molecular mechanisms underlying the effects of TNFRSF13B were further explored by microarray gene expression profiling. (biomedcentral.com)
Proteins involved1
  • Genes encoding proteins involved in processing of drugs and other xenobiotics. (gsea-msigdb.org)
Ortholog1
  • We have identified the DAD2 gene from petunia, an ortholog of the rice and Arabidopsis D14 genes, and present evidence for its roles in strigolactone perception and signaling. (inra.fr)
Resistance genes1
  • While the genetic architecture of NCLB has been well characterized, the pathogen is known to overcome currently deployed resistance genes, and the role of hormones in resistance to NCLB is an area of active research. (frontiersin.org)
Enzymes3
  • Over the past decade, it has been well established that PXR functions as a master-regulator of xenobiotic- and drug-inducible expression and activity of numerous genes that encode key members of the phase I and phase II metabolic enzymes, as well as several membrane transporter proteins. (ku.edu)
  • To detect these cues, moths have evolved families of genes encoding elements of the peripheral olfactory reception system, including odor carriers, receptors and degrading enzymes. (inra.fr)
  • Species associated to Bacteroidetes showed a high proportion of genes for debranching and oligosaccharide degrading enzymes, while those belonging to Firmicutes and Fibrobacteres were rich in cellulases and hemicellulases and thus these lineages were probably the key for ensuring the degradation of lignocellulose. (biomedcentral.com)
Genomic3
  • Whole genome re-sequencing provides powerful data for population genomic studies, allowing robust inferences of population structure, gene flow and evolutionary history. (biomedcentral.com)
  • These gene clusters of various sizes correspond predominantly to low recombination genomic regions such as inversions and centromeres, and also to recent selective sweeps. (biomedcentral.com)
  • shortening the time required to progress from field sampling to the identification of genes and genomic regions under unique evolutionary processes. (biomedcentral.com)
Expression8
  • An integrated model is emerging to reveal a key role for the post-translational modification of PXR in the selective suppression of gene expression, and is opening the door to the study of completely new modes of PXR-mediated gene regulation. (ku.edu)
  • encodes a protein that is induced in expression in response to water deprivation such as cold, high-salt, and dessication. (or.jp)
  • 2014), to overlap differentially overexpressed genes right after the therapies and to examine gene expression among response to BP178 and the other remedies, is shown in Figure 3. (atminhibitor.com)
  • The code quantity at GEO webpage for the accession is GSE183707.Quantitative Real-Time PCR AnalysesRT-qPCR was performed with 14 chosen defense genes in order to validate the gene expression profile revealed by microarrays analysis in response to BP178 treatment. (atminhibitor.com)
  • These items interact with plant-signaling cascades that triggered the expression of stress-responsive genes. (atminhibitor.com)
  • The JA and coumarin treatments suppressed the vitellogenin gene (TcVg6) expression level. (bvsalud.org)
  • Exogenous DTD treatment did not elicit expression of defense-related genes in the host plant but did trigger the necrosis of C. gloeosporioides. (inra.fr)
  • Tissue-specifically expressed genes were extracted based on the expression frequency among the libraries. (biomedcentral.com)
Humans2
  • Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. (nih.gov)
  • The high-affinity choline transporter (ChT) also known as solute carrier family 5 member 7 is a protein in humans that is encoded by the SLC5A7 gene. (csnpharm.cn)
Variants5
  • Multiple transcript variants encoding different isoforms have been found for this gene. (utsouthwestern.edu)
  • Alternative splicing results in multiple transcript variants encoding distinct isoforms. (nih.gov)
  • Therefore, the aim of this study was to evaluate the effects of common genetic variants among eight immunodeficiency pathway-related genes on disease recurrence in prostate cancer patients treated with radical prostatectomy. (biomedcentral.com)
  • However, no study has yet systematically investigated the effect of gene variants related to immunodeficiency on prostate cancer progression. (biomedcentral.com)
  • In the present study, we first conducted a genetic analysis to evaluate the effects of common variants among eight immunodeficiency pathway-related genes on disease recurrence in 458 patients with prostate cancer after receiving radical prostatectomy. (biomedcentral.com)
Genome2
  • PCR analysis revealed that the genes exclusively expressed in the HN1 variety are present as expected in the genome of HN1 but absent from the genomes of the HM1 and HT1 varieties ( Fig. 1B and fig. S6). (ampliconexpress.com)
  • Identification of genes exclusively present in the genome of a noscapine producing poppy variety, HN1 (High Noscapine 1). (ampliconexpress.com)
Synthesis1
  • An analysis of VFA biosynthesis pathways showed that genes required for the synthesis of acetate were present in a range of species, except for Elusimicrobiota and Euryarchaeota . (biomedcentral.com)
Reductase1
Tissues1
  • Information of genes working in various tissues at various growth stages is extremely useful for molecular functional study in biology. (biomedcentral.com)
Analyses2
  • The EST library will provide useful information for transcriptional analyses, proteomic analyses, and gene functional analyses of BPH. (biomedcentral.com)
  • Genetic and bioinformatic analyses on 19 haplotype-tagging single-nucleotide polymorphisms in eight immunodeficiency pathway-related genes were conducted in 458 patients with prostate cancer after receiving radical prostatectomy. (biomedcentral.com)
Characterization1
  • This suite of olfaction-related genes provides a substantial resource for the functional characterization of this signal transduction system and the development of odor-mediated control strategies for horticultural pests. (inra.fr)
Symbol1
Transcriptomic1
  • Here we undertake a transcriptomic approach to identify members of these families expressed in the adult antennae of E. postvittana, describing open reading frames encoding 34 odorant binding proteins, 13 chemosensory proteins, 70 odorant receptors, 19 ionotropic receptors, nine gustatory receptors, two sensory neuron membrane proteins, 27 carboxylesterases, 20 glutathione-S-transferases, 49 cytochrome p450s and 18 takeout proteins. (inra.fr)
Rice1
  • Elucidation of rice plants' genes that increase resistance against planthoppers and BPH virulence mechanisms against the resistant rice plants have become important tasks. (biomedcentral.com)
Plant3
  • Except the hydrolase, each of the other genes code for proteins straight involved in plant-defense responses. (atminhibitor.com)
  • Contrarily, the remedy with all the bactericidal peptide BP100 caused a slight overexpression of only one particular out of 14 genes (e.g., polyphenol oxidase).DISCUSSIONBiostimulant Kinesin-14 Gene ID application in agriculture represents a highly effective strategy to improve both plant yield and tolerance to abiotic and biotic stresses (Rouphael and Colla, 2020). (atminhibitor.com)
  • Analysis of an F2 mapping population indicated the genes are tightly linked in HN1, and bacterial artificial chromosome sequencing confirmed they exist as a complex gene cluster for plant alkaloids. (ampliconexpress.com)
Family5
  • Carboxylesterase 3 is a member of a large multigene family. (wikipedia.org)
  • This gene encodes a member of the carboxylesterase large family. (utsouthwestern.edu)
  • Encodes a member of the MATE (multidrug and toxin efflux family), expressed in roots but not shoots. (or.jp)
  • Protein is a member of a gene family with other members found plants, animals and fungi. (or.jp)
  • The N-Myc downstream-regulated gene (NDRG) family belongs to the alpha/beta-hydrolase fold and is known to exert various physiologic functions in cell proliferation, dierentiation, and hypoxia-induced cancer metabolism. (inra.fr)
Sequences1
  • There was also a substantial representation of sequences encoding scaffoldins, dockerins and cohesins, indicating the potential for cellulosome-mediated lignocellulose degradation. (biomedcentral.com)
Prostate1
  • The present study suggests the potential role of immunodeficiency pathway-related genes, primarily TNFRSF13B , in prostate cancer progression. (biomedcentral.com)
Activity2
  • Encodes a protein with nicotianamine synthase activity. (or.jp)
  • In this study, we observed the hydrolyzing activity of a fungus-inducible pepper carboxylesterase (PepEST) on cell walls of C. gloeosporioides, causing growth retardation of the fungus by blocking appressorium formation. (inra.fr)
Mouse1
Previously1
  • Analysis of Expressed Sequence Tag (EST) abundance led to the discovery of a number of previously uncharacterized genes that are expressed in the HN1 variety but are completely absent from the HM1 and HT1 EST libraries ( Fig. 1B ). (ampliconexpress.com)
Show2
  • Click Gene ID to show a list of GSM assays in which the gene are specifically expressed. (or.jp)
  • Among the top ten most abundantly expressed genes, three are unique and show no homology in BLAST searches. (biomedcentral.com)
Numerous1
  • The map allows intuitive navigation among genes distributed throughout the so-called "mainland" and numerous surrounding "island-like" gene clusters. (biomedcentral.com)
Multiple1
  • Both qualitative resistance, conferred by a single gene, and quantitative resistance, conferred by multiple genes, have been characterized in maize. (frontiersin.org)
Population1