• Plant TCS components typically consist of three signal transducers, namely hybrid HKs with both a His-kinase (HK) domain and a receiver (Rec) domain, histidine-containing phosphotransfers (HPs), and RRs. (frontiersin.org)
  • Two-component phosphorelay systems are minimally comprised of a histidine kinase (HK) component, which autophosphorylates in response to an environmental stimulus, and a response regulator (RR) component, which transmits the signal, resulting in an output such as activation of transcription, or of a mitogen-activated protein kinase cascade. (asm.org)
  • Two-component histidine kinase (HK) phosphorelay signaling systems are a major mechanism by which some organisms sense and adapt to their environment. (asm.org)
  • We demonstrated that expression of the HP166-HP165 two-component system is negatively autoregulated under conditions favoring autophosphorylation of the histidine kinase. (asm.org)
  • Abstract details the testing of the association between 76 candidate genes and bipolar disorder, identifying brain-derived neurotrophic factor (BDNF) as a potential risk that will require additional study. (dmoztools.net)
  • This system allows conditional tissue-specific ectopic gene expression and provides a tool for conditional cell type- or tissue-specific complementation of mutants. (plantphysiol.org)
  • Conditional and cell type-specific gene expression systems allow precise functional complementation of mutants, disclosing the spatial and temporal significance of a gene's expression profile at different stages in development. (plantphysiol.org)
  • Such a system that could also allow conditional cell type-specific activation of randomly tagged genes would provide the versatility required to identify classes of mutants with tissue-specific effects or mutants with early lethal effects. (plantphysiol.org)
  • Besides the already mentioned differences in TLC1 and TERRA levels in strains lacking different PAF1 complex components, there is also a strong difference in fitness amongst the different PAF1 deletion mutants. (springer.com)
  • Numerous stress- and hormone-responsive cis -elements were detected in the putative promoter regions of the cucumber TCS genes. (frontiersin.org)
  • Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. (uniprot.org)
  • Genetic analysis of rhizobia has led to identification of nod genes, which are involved in the control of host specificity, infection, and nodulation. (plantcell.org)
  • A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome. (sigmaaldrich.com)
  • Sequencing identified a single heterozygous mutation in the H box of the patient's TERC gene. (sigmaaldrich.com)
  • According to Zonana's hypothesis, a mutation affecting the external portion of the protein would wipe out the signal-binding activity of one gene product, but the presence of a second normal gene could compensate for the loss. (bio-medicine.org)
  • This type of mutation would require a defective gene from each parent in order to produce abnormal development. (bio-medicine.org)
  • The telomerase RNA component (TERC) is an essential element of telomerase, serving as a template for telomere elongation. (sigmaaldrich.com)
  • Finally, we show that deletion of ESCRT components decreases the telomere length in the S288C yeast genetic background, but not in the W303 background. (springer.com)
  • Together, our results outline complex interactions, in cis and in trans , between genes encoding PAF1 and ESCRT-II complex components that affect telomere function and cell viability in yeast. (springer.com)
  • Finally, genetic screens have shown that Cdc73, Leo1, and Rtf1 are important for the fitness of telomere defective cells (carrying a cdc13-1 temperature-sensitive allele of the telomere capping gene CDC13 ) (Addinall et al. (springer.com)
  • A betasatellite-encoded protein regulates key components of gene silencing system in plants Eini, O. 2017-08-23 00:00:00 Small circular single-stranded DNA satellites, called betasatellites, have been found in association with some monopartite begomovirus infections. (deepdyve.com)
  • CLCuMuB contains a single gene, βC1, whose product is a pathogenicity determinant and a suppressor of RNA silencing. (deepdyve.com)
  • The purpose of CSA is to provide initial evidence that a single gene has a major effect on a particular phenotypic trait. (wikipedia.org)
  • CSA can provide evidence, but not definitively prove a trait is under the control of a single gene. (wikipedia.org)
  • Plant disease resistance ( R ) genes trigger innate immune responses upon pathogen attack. (sciencemag.org)
  • Furthermore, the RAR1-SGT1 complex also interacts with two COP9 signalosome components. (sciencemag.org)
  • This cluster is not linked to the major histocompatibility complex, which contains the genes for the complement components, C4, C2, and factor B, or to the C3 locus. (rupress.org)
  • We found that RNA levels of VPS36 , but not other ESCRT components, are positively regulated by all components of the PAF1 complex. (springer.com)
  • In yeast, CDC73 , encoding a component of the PAF1 complex, is adjacent to VPS36 , encoding a component of the ESCRT machinery and the two genes have been suggested to show an adjacent gene effect (Ben-Shitrit et al. (springer.com)
  • We have identified an essential gene, called FIP1, encoding a 327 amino acid protein interacting with yeast poly(A) polymerase (PAP1) in the two-hybrid assay. (epfl.ch)
  • Meanwhile, quantitative real-time PCR indicated that most of the TCS genes in cucumber were specifically or preferentially expressed in certain tissues or organs, especially in the early developing fruit. (frontiersin.org)