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CholecystokininReceptors, CholecystokininReceptor, Cholecystokinin AReceptor, Cholecystokinin BSincalideDevazepideProglumideBenzodiazepinonesTetragastrinPancreasGastrinsGallbladderGallbladder EmptyingAmylasesSatiationSecretinCeruletideGabexateHormone AntagonistsDuodenumSatiety ResponseGastrointestinal HormonesPancreatic JuicePancreatic PolypeptideEnteroendocrine CellsEatingGastric EmptyingPentagastrinBombesinCholecystographyPeptide YYAzaserinePancreas, ExocrineTechnetium Tc 99m DisofeninImino AcidsChymotrypsinogenBiliopancreatic DiversionSphincter of OddiPeptonesPhenylurea CompoundsGastrointestinal MotilityAppetite RegulationAppetiteRats, Sprague-DawleyVagus NerveMeglumineDibutyryl Cyclic GMPStomachHungerPostprandial PeriodBiliary DyskinesiaDose-Response Relationship, DrugRats, Inbred StrainsCholagogues and CholereticsNodose GanglionTrypsinogenSomatostatinVasoactive Intestinal PeptideRadioimmunoassayCarbacholBenzodiazepinesTechnetium Tc 99m LidofeninCystic DuctGlobulinsPentanoic AcidsAppetite DepressantsPylorusTrypsin InhibitorsNeuropeptides
Differentially expressed genesReceptorsMRNA expressionCCKBRCalcitoninOxidative stressPeptidesDopaminergicPancreaticProteinRegulationSecretionLigandDuodenumExpressionProteinsStimulatesTherapeuticFragmentFamilialSchizophreniaGeneticParkinson'sMicroarrayInteractionDiseasesFattyTranscription factorsDiagnosticDisordersTumorAnxietyAnalysisFunctionCarry
Differentially expressed genes3
  • The differentially expressed genes (DEGs) in AD were screened in GSE48350 dataset. (nature.com)
  • Validated multiple differentially expressed genes (DEGs), such as glycine receptor subunit 2 and cholecystokinin, at the transcript and/or protein levels, supporting the relevance of these genes to CDKL5-regulated excitability. (cureepilepsy.org)
  • 600 genes differentially expressed during Leber congenital amaurosis_Retina_GSE3249 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. (maayanlab.cloud)
Receptors4
  • We investigated the spatial (brain and gut) and temporal (10 and 20 dpff) expression profile of cholecystokinin paralogues (cck1 and cck2) and its receptors (cck1r, cck2r1 and cck2r2), neuropeptide y and peptide yy paralogues (pyya and pyyb). (uib.no)
  • Members of the cholecystokinin (CCK)/gastrin family of peptides, including the arthropod sulfakinins, and their cognate receptors, play an important role in the regulation of feeding behavior and energy homeostasis. (uantwerpen.be)
  • The Caenorhabditis elegans genome contains two genes with high identity to the mammalian CCK receptors and their invertebrate counterparts, the sulfakinin receptors. (uantwerpen.be)
  • In this laboratory we perform case-control association studies for different polymorphisms of candidate genes such as cholecystokinin, dopaminergic and serotonergic receptors and neurodevelopmental genes (ASPM, FOXP2). (uv.es)
MRNA expression4
  • The mRNA expression of diagnostic genes was determined by qRT-PCR analysis. (nature.com)
  • Liver, muscle, and intestine tissue samples were taken to measure mRNA expression of key genes involved in glucose, lipid, and protein metabolism. (frontiersin.org)
  • ITT, GTT, and MTT showed that CS rats were neither insulin resistant nor glucose intolerant, but mRNA expression of cholecystokinin (CCK) in the duodenum was higher and that of CPT1, PPARα, and PGC1α in liver were lower than in CR rats. (frontiersin.org)
  • Subsequently, we decided to analyse the mRNA expression of genes known to be involved in control of feed intake, appetite and digestion in teleost species. (uib.no)
CCKBR2
  • The CCKBR is a regulatory gene involved in inducing crow sounds in roosters. (researchgate.net)
  • An increased CCKBR gene expression in chicks induced by testosterone can make them crow [34] . (researchgate.net)
Calcitonin3
  • In contrast, quantification of calcitonin gene-related peptide (CGRP)-like peptides demonstrated an increase in CGRP-like activities in the UF permeate, relative to the starting FPH. (ifremer.fr)
  • Distribution of cholecystokinin, calcitonin gene-related peptide, neuropeptide Y, and galanin in the primary gustatory nuclei of the goldfish. (ucdenver.edu)
  • Stimulation of calcitonin gene-related peptide release may partially explain the analgesic, cardiovascular and gastrointestinal protective, anti-obese activities of Evodia rutaecarpa and its major bioactive components. (biomedcentral.com)
Oxidative stress3
  • The differentially expressed oxidative stress genes (DEOSGs) were analyzed by intersection of DEGs and oxidative stress-related genes. (nature.com)
  • Our study identified 9 key genes associated with oxidative stress and immune reaction in AD pathogenesis. (nature.com)
  • Oxidative stress is involved in the modulation of gene expression patterns and metabolic activities, characterized by the disruption of redox homeostasis 7 . (nature.com)
Peptides1
  • Gastrin/cholecystokinin-like peptides were present in the starting FPH, UF and NF fractions, but fractionation did not increase their concentration. (ifremer.fr)
Dopaminergic1
  • Here we summarize the present knowledge on the molecular etiology and genetic determinants of eating disorders including serotonergic genes, dopaminergic genes, opioid genes, appetite regulation genes, endocannabinoid genes and vitamin D3. (jpmh.org)
Pancreatic1
  • Mechanism of cholecystokinin-A- receptor antagonist on human pancreatic exocrine secretion. (wikipedia.org)
Protein8
  • The Cholecystokinin A receptor is a human protein, also known as CCKAR or CCK1, with CCK1 now being the IUPHAR-recommended name. (wikipedia.org)
  • This gene encodes a G-protein coupled receptor that binds sulfated members of the cholecystokinin (CCK) family of peptide hormones. (wikipedia.org)
  • The immune-related DEOSGs and hub genes were identified by weighted gene co-expression network analysis (WGCNA) and protein-protein interaction (PPI) analysis, respectively. (nature.com)
  • FUNCTION: This gene encodes a multipass transmembrane receptor protein expressed in the central nervous system and gastrointestinal tract. (utsouthwestern.edu)
  • Cholecystokinin and gastrin bind to the encoded protein to stimulate gastric acid secretion and mucosal growth in the gastrointestinal tract, and anxiety, pain sensation and memory in the brain. (utsouthwestern.edu)
  • Research has also demonstrated that pea protein stimulates release of cholecystokinin and glucagon-like peptide 1, gastrointestinal hormones that modulate appetite sensations. (healthyplanetcanada.com)
  • This gene encodes a protein that contains an immunoglobulin-like domain. (utsouthwestern.edu)
  • Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. (utsouthwestern.edu)
Regulation3
  • Up-regulation of many of these genes can be explained as negative feedback, attenuating CRF-activated pathways. (aspetjournals.org)
  • We intend to carry out the analysis of the function and regulation of gene of Drosophila melanogaster homologous to the gene responsible for Friedreich's ataxia, as well as to perform a pharmacological screening of compounds with therapeutic activity. (uv.es)
  • Over the last decade, the McClung lab has described the mechanisms by which circadian genes are intimately involved in the regulation of the brain's reward and mood-related circuitry using mouse models. (pitt.edu)
Secretion1
Ligand1
Duodenum1
Expression3
  • expression analysis to identify genes that induce crowing. (researchgate.net)
  • The aim of the study was to determine whether ghrelin treatment has a protective effect on gene expression and biochemical changes in the stomach of newborn streptozotocin (STZ) induced diabetic rats. (bilim.edu.tr)
  • The expression of this gene may be a diagnostic marker for cancer progression. (utsouthwestern.edu)
Proteins1
  • ebook der tägliche gang der Proteins: The hypertension genes of heart, the medical institutes maximizing ACTINS and MYOSIN. (augenta.net)
Stimulates1
  • In this scholarly study, we discovered with a cell tradition program that DJ-1 stimulates manifestation from the gene in the transcriptional level by association with RREB1 which the decreased CCK level in the serum from DJ-1-knockout mice in comparison to that from wild-type mice was noticed. (biodiversityhotspot.org)
Therapeutic2
  • Investigation of hub genes for the development of potential therapeutic targets and candidate biomarkers is warranted. (nature.com)
  • Background Oncolytic disease which hands the therapeutic gene to improve anti-tumor activity is a common technique to improve oncovirotherapy of tumor. (immune-source.com)
Fragment1
  • Tyr (SO3H) 27-cholecystokinin fragment*2 (CCK) Z-Val-Phe methyl ester (ZVP) & most various other chemicals utilized had been extracted from Sigma. (academicediting.org)
Familial1
  • Unusually low levels of triglycerides can be present in disease states, producing syndromes of malabsorption in addition to patients who carry genes for familial hypobetalipoproteinemia . (medscape.com)
Schizophrenia1
  • Genetic mapping in schizophrenia and analysis of candidate genes. (uv.es)
Genetic2
  • Other types of genetic studies, including genome-wide association studies, whole genome sequencing and linkage analysis, allowed to identify the genes and their variants associated with eating disorders and moreover global collaborative efforts have led to delineate the etiology of these disorders. (jpmh.org)
  • Analysis of association between genetic and environmental variables in a sample of 800 children, with an emphasis on gene-environment interactions in the acquisition of language and temperament in children. (uv.es)
Parkinson's1
  • It was also discovered as a gene mutated in some rare famial forms of Parkinson's disease. (neuromics.com)
Microarray2
  • To elucidate gene networks regulated by CRF and CRFR1, we applied microarray technology to explore transcriptional response to CRF stimulation. (aspetjournals.org)
  • We previously sought out genes whose manifestation was transformed in DJ-1-knockdown cells in comparison to that in parental cells with a DNA microarray, and we determined many applicant genes, like the cholecystokinin (CCK) gene [17]. (biodiversityhotspot.org)
Interaction1
  • The debate whether gene or environment is primary in anxiety disorders has evolved to a better understanding of the important role of the interaction between genes and environment. (health.am)
Diseases1
  • Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. (novusbio.com)
Fatty1
  • that is, upregulating genes that affect hepatic cholesterol uptake and downregulating genes that affect fatty acid synthesis. (healthyplanetcanada.com)
Transcription factors1
  • Finally, we constructed the drug, transcription factors (TFs), and microRNA network of the diagnostic genes. (nature.com)
Diagnostic1
  • The diagnostic value of hub genes was assessed by receiver operating characteristic analysis and validated in GSE1297. (nature.com)
Disorders2
  • Cholecystokinin (CCK) involvement in depression-like disorders is poorly documented. (nih.gov)
  • Gene variants in Eating Disorders. (jpmh.org)
Tumor1
  • Viral replication and virulence weren't attenuated from the incorporation of cHAb18 gene ICOS which considerably improved the suppression of relict tumor cell migration. (immune-source.com)
Anxiety1
  • Cholecystokinin B (CCK B ) agonists increase "anxiety" in laboratory animals and induce "panic" in humans. (jneurosci.org)
Analysis2
  • Enrichment analysis was performed by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. (nature.com)
  • We obtained 66 immune-related DEOSGs by intersecting turquoise module with the DEOSGs and identified 15 hub genes through PPI analysis. (nature.com)
Function1
Carry1
  • By reverse genetics technology we shown that NDV Italien was able to carry exogenous genes without influencing computer virus replication [7]. (immune-source.com)