Gene aspergillus oryzae. Medical search. Frequent questions

Here we show that the 37-megabase (Mb) genome of A. oryzae contains 12,074 genes and is expanded by 7-9 Mb in comparison with the genomes of Aspergillus nidulans 5 and Aspergillus fumigatus 6 . (nature.com)
Comparison of the three aspergilli species revealed the presence of syntenic blocks and A. oryzae -specific blocks (lacking synteny with A. nidulans and A. fumigatus ) in a mosaic manner throughout the genome of A. oryzae . (nature.com)
The A. oryzae genome is larger than those of A. fumigatus and A. nidulans by approximately 34% and 29%, respectively. (nature.com)
Phylogenetic analysis of the three aspergilli using the whole-genome data showed that A. nidulans branched off earlier than A. oryzae and A. fumigatus 5 . (nature.com)
Thus, the increase in genome size seems to be due to an A. oryzae lineage-specific acquisition of sequence, rather than loss of sequence in A. nidulans and A. fumigatus . (nature.com)
If, on the other hand, A. nidulans and A. fumigatus are assumed to have lost 7-9 Mb of sequence after branching off from their A. oryzae -like ancestor, a greater proportion of syntenic blocks would be conserved between each of them and A. oryzae than between the two. (nature.com)
Here, we first developed a CRISPR/Cas9 system in Aspergillus oryzae using AMA1-based autonomously replicating plasmid and Cas9 under the control of the Aspergillus nidulans gpdA promoter. (olmdiagnostics.com)
natural variation in bcvel1 encoding the ortholog of aspergillus nidulans vea, a member of the velvet complex, was previously shown to affect light-dependent differentiation, the formation of oxalic acid (oa), and virulence. (liverpool.ac.uk)
negative regulation of the vacuole-mediated resistance to k(+) stress by a novel c2h2 zinc finger transcription factor encoded by asla in aspergillus nidulans. (liverpool.ac.uk)
in the filamentous fungus aspergillus nidulans, however, little is known about the molecular genetic mechanisms of vacuolar biogenesis and function. (liverpool.ac.uk)
a mutation in the converter subdomain of aspergillus nidulans myob blocks constriction of the actomyosin ring in cytokinesis. (liverpool.ac.uk)
aspergillus nidulans causing primary cutaneous aspergillosis in an immunocompetent patient. (liverpool.ac.uk)
pasop carries a selectable marker, pyrg, derived from aspergillus nidulans, and a strong promoter and a terminator of the amyb gene derived from a. oryzae. (liverpool.ac.uk)
continuous xylanase production with aspergillus nidulans under pyridoxine limitation using a trickle bed reactor. (liverpool.ac.uk)
a trickle bed reactor (tbr) with recycle was designed and tested using aspergillus nidulans with a pyridoxine marker and over-expressing/secreting recombinant client xylanase b (xynb). (liverpool.ac.uk)
nidulans (anamorph: aspergillus nidulans) on the basis of rdna its1 and rdna its2 region sequences. (liverpool.ac.uk)
comprehensive genomic analysis of cell wall genes in aspergillus nidulans. (liverpool.ac.uk)
the cell wall of aspergillus nidulans is composed of galactomannoproteins, 1,3-alpha-glucan, beta-glucans, and chitin. (liverpool.ac.uk)
here, we present a comprehensive inventory of the cell wall-related genes in a. nidulans. (liverpool.ac.uk)
characterization of nika histidine kinase and two response regulators with special reference to osmotic adaptation and asexual development in aspergillus nidulans. (liverpool.ac.uk)
aspergillus nidulans has many histidine-to-aspartate (his-asp) phosphorelay components, including 15 histidine kinases (hks), four response regulators (rrs), and a histidine-containing phosphotransfer intermediate (hpt). (liverpool.ac.uk)
this agent is a semisynthetic lipopeptide synthesized from a fermentation product of aspergillus nidulans. (liverpool.ac.uk)
riok3 was initially characterized as a homolog of aspergillus nidulans sudd and showed down-regulation at the invasive front of malignant melanomas, but the molecular mechanism remains elusive. (liverpool.ac.uk)
The third paper reports the genome sequence of model organism Aspergillus nidulans and compares the organism to A. oryzae and A. fumigatus . (sciencedaily.com)

Incidentally, in China and Korea, the fungi used for fermented foods for a long time in the production of traditional alcoholic beverages were not A. oryzae but fungi belonging to Rhizopus and Mucor. (wikipedia.org)
While the two fungi share the same cluster of genes that encode for aflatoxin synthesis, this gene cluster is non-functional in A. oryzae. (wikipedia.org)
Large-scale genomics and transcriptomics approaches have been proven to enable the identification of pathogenicity genes in fungi affecting humans or plants [ 8 ], which makes them valuable tools towards a better understanding of fungal infection mechanisms. (biomedcentral.com)
These rapid adaptations in fungi provide excellent models for studying general processes of eukaryotic genome evolution, including the functional and ecological impact of horizontal gene transfer 1 and changes in metabolism 2 . (nature.com)
The CRISPR/Cas9 system has become a great tool for target gene knock-out in filamentous fungi. (olmdiagnostics.com)
Filamentous fungi such as Aspergillus niger and Trichoderma reesei are the workhorses of industry for the production of extracellular enzymes. (biomedcentral.com)
elimination of marker genes from transformed filamentous fungi by unselected transient transfection with a cre-expressing plasmid. (liverpool.ac.uk)
A total of 28.9% (4232) of HGCC genes, 29.5% (4298) of CCP genes and 28.6% (4214) of UM591 genes were highly homologous to experimentally proven virulence-associated genes, respectively, which were not significantly different ( P = 0.866) from the average (29.7%) of 10 other phytopathogenic fungi. (biomedcentral.com)
A. oryzae is one of the most famous food fungi. (anmicro.org)

Genomic analysis has led some scholars to believe that the Japanese domesticated the Aspergillus flavus that had mutated and ceased to produce toxic aflatoxins, giving rise to A. oryzae. (wikipedia.org)
We and other groups discovered the human IL-17F gene from a human EST sequence, a genomic DNA clone, and T-cell cDNA sequences in 2001 [ 3 , 8 , 9 ]. (hindawi.com)
An annotated genomic sequence of the corn anthracnose fungus Colletotrichum graminicola has been published previously, but correct identification of gene models by means of automated gene annotation remains a challenge. (biomedcentral.com)

Rhizopus oryzae was the causative organism. (medscape.com)

Genichirō Kawachi (1883 -1948), who is said to be the father of modern shōchū and Tamaki Inui (1873 -1946), a lecturer at University of Tokyo succeeded in the first isolation and culturing of aspergillus species such as A. kawachii, A. awamori, and a variety of subtaxa of A. oryzae, which let to great progress in producing shōchū in Japan. (wikipedia.org)
Among the nTARs, 146 share significant similarity with proteins that have been identified in other species suggesting that they are hitherto unidentified genes in C. graminicola . (biomedcentral.com)
Among these genera, Aspergillus oryzae is of particular interest in the context of malic acid production with bio-based substrates as this species exhibits a high tolerance against biomass-derived inhibitors [ 9 ]. (biomedcentral.com)
The genera Aspergillus and Penicillium include some of the most beneficial as well as the most harmful fungal species such as the penicillin-producer Penicillium chrysogenum and the human pathogen Aspergillus fumigatus, respectively. (umd.edu)
Here we report the complete sequence and annotation of the mitochondrial genomes of six Aspergillus and three Penicillium species: A. fumigatus, A. clavatus, A. oryzae, A. flavus, Neosartorya fischeri (A. fischerianus), A. terreus, P. chrysogenum, P. marneffei, and Talaromyces stipitatus (P. stipitatum). (umd.edu)
All of the sequenced genomes have a group I intron in the large ribosomal subunit RNA gene, suggesting that this intron is fixed in these species. (umd.edu)
Despite the conservation of the core genes, the mitochondrial genomes of Aspergillus and Penicillium species examined here exhibit significant amount of interspecies variation. (umd.edu)
Orofacial lesions caused by Aspergillus species include antral aspergilloma, invasive aspergillosis of the antrum, indolent chronic sinusitis, allergic sinusitis, and oral lesions. (medscape.com)

Although both A. oryzae and Aspergillus flavus belong to the section Flavi of the subgenus Circumdati of Aspergillus , A. oryzae , unlike A. flavus , does not produce aflatoxin, and its long history of use in the food industry has proved its safety. (nature.com)
The expansion in genome size appears to be characteristic of the organisms closely related to A. oryzae , as the estimated genome size of its close relatives A. flavus (W. Nierman, personal communication) and Aspergillus niger 8 is comparable to that of A. oryzae . (nature.com)
The pre-harvest biocontrol approach currently used includes laboratory inoculations using non-aflatoxigenic strains of Aspergillus flavus. (encyclopedia.pub)
Aflatoxins (AFs) are predominantly produced by Aspergillus flavus and A. parasiticus . (encyclopedia.pub)

Reconstitution of biosynthetic genes in a heterologous host is a newly emerging method for synthesis of fungal secondary metabolites. (heterocycles.jp)
Besides being the first heterologous expression and characterization of a gene coding for a lipase from A. alcalophilum , this report shows that LipA is very versatile exhibiting both acetylxylan esterase and lipase activities potentially useful for diverse industry sectors, and that tobacco is a suitable bioreactor for producing fungal proteins. (biomedcentral.com)
construction of a shuttle vector for heterologous expression of a novel fungal α-amylase gene in aspergillus oryzae. (liverpool.ac.uk)
the spectrum of activity of anidulafungin includes candida and aspergillus, the two main etiological agents causing invasive fungal infections. (liverpool.ac.uk)
The genome could lead researchers to A. fumigatus genes with the potential to generate better diagnostics and treatment for fungal infection. (sciencedaily.com)
Dr. Jeennor found that genetically-engineered Ags1 gene caused crucial changes in A. oryzae's cell walls, resulting in smaller fungal pellets. (anmicro.org)
Heterologous expression of the spo genes in Aspergillus oryzae then led to the production of intermediates and shunts and delineation of a new fungal biosynthetic pathway originating in fatty acid biosynthesis. (uni-hannover.de)
We developed a high-throughput gene knockout system, and using this system, we obtained null mutants of 104 fungal-specific Zn2Cys6 transcription factor (TF) genes by screening 8741 primary transformants in M. oryzae. (prelekara.sk)
We found that 61 Zn2Cys6 TF genes play indispensable and diversified roles in fungal development and pathogenicity. (prelekara.sk)

For the construction of an overexpression system of the intracellular 1,2-α-mannosidase (EC 3.2.1.113) gene (msdS) from Aspergillus saitoi (now designated Aspergillus phoenicis), the N-terminal signal sequence of the gene was replaced with that of the aspergillopepsin I (EC 3.4.23.18) gene (apnS) signal, one of the same strains as described previously. (elsevierpure.com)
This discovery may pave the way to high-yield A. oryzae strains. (anmicro.org)

The project focused on understanding the biosynthesis of sporothriolides, sporochartines and trienylfuranol A. Gene cluster identification, gene knock out, heterologous expression and protein in vitro assays were used during the investigation. (uni-hannover.de)
Several hrPKS gene clusters were identified as the potential polyene BGC for trienylfuranol A 2 through multiple bioinformatic analysis, however metabolites produced from the PKS in heterologous expression belong to either different polyene type compounds or pyrone derivatives. (uni-hannover.de)
However, we previously demonstrated that the grisemycin (grm) cluster contained cryptic dehydratase and epimerase genes by heterologous expression of this biosynthetic gene cluster in Streptomyces lividans and proposed that two genes (grmH and grmL) with unknown functions catalyze dehydration and epimerization reactions. (hokudai.ac.jp)

knowledge of the mechanisms underlying cell wall biosynthesis in aspergillus spp. (liverpool.ac.uk)
Suspect genes encode proteins involved in central metabolic pathways, cell signaling, cell wall biosynthesis, pigment biosynthesis, and secondary metabolite production. (sciencedaily.com)
He "hijacked" the natural valine biosynthesis in Pichia pastoris using the conventional gene reconstitution and modern CRISPR-Cas9 fine-tuning. (anmicro.org)

The 37-Mb genome was predicted to contain a total of 12,074 genes encoding proteins with a length greater than 100 amino acid residues (see Methods). (nature.com)
functional characterization of nat/ncs2 proteins of aspergillus brasiliensis reveals a genuine xanthine-uric acid transporter and an intrinsically misfolded polypeptide. (liverpool.ac.uk)
the filamentous fungus aspergillus oryzae is a well-known expression host used to express homologous and heterologous proteins in a number of industrial applications. (liverpool.ac.uk)
to facilitate higher yields of proteins of interest, we constructed the pasop vector to express heterologous proteins in a. oryzae. (liverpool.ac.uk)
The sources of genome expansion include group I introns and accessory genes encoding putative homing endonucleases, DNA and RNA polymerases (presumed to be of plasmid origin) and hypothetical proteins. (umd.edu)
Moreover, O. thermomethalonica has a stable capability to integrate plasmid into its own cell, thus scientists can transfer genes from other organisms into O. thermomethalonica and harvest the proteins easily and reliably. (anmicro.org)

The strain A. oryzae RIB40, for example, appears to have specific salt tolerance genes that regulate K+ transport. (wikipedia.org)

Aspergillus oryzae, also known as kōji mold (Japanese: ニホンコウジカビ (日本麹黴), Hepburn: nihon kōji kabi), is a filamentous fungus (a mold) used in East Asia to saccharify rice, sweet potato, and barley in the making of alcoholic beverages such as sake and shōchū, and also to ferment soybeans for making soy sauce and miso. (wikipedia.org)
The Japanese dynasty and nation have domesticated and utilized koji fermented with non-pathogenic fungus Aspergillus oryzae for more than 1300 years. (mdpi.com)
We successfully employed deep sequencing RNA-Seq data in combination with an elaborate bioinformatics strategy in order to identify novel genes, incorrect gene models and mechanisms of transcript processing in the corn anthracnose fungus C. graminicola . (biomedcentral.com)
The genome of Aspergillus oryzae , a fungus important for the production of traditional fermented foods and beverages in Japan, has been sequenced. (nature.com)
The fungus becomes a human pathogen because it's perfectly comfortable at body temperature, 37 degrees C. Altering ambient temperatures in the lab, TIGR scientists tracked gene activity, documenting different A. fumigatus genes that turned on and off, as the environment warmed. (sciencedaily.com)
Some 700 A. fumigatus genes significantly differ--or do not even occur--in a similar, yet less infectious fungus, Neosartorya fischeri . (sciencedaily.com)
Magnaporthe oryzae is not only the fungus causing the rice blast disease, which leads to 20-30% losses in rice production, but also a primary model pathosystem for understanding host-pathogen interactions. (prelekara.sk)
However, there is no high-throughput gene knockout system constructed, and little is known about most of the genes in this fungus. (prelekara.sk)
CNF1 is the first reported TF gene that strongly and negatively regulates asexual development in the rice blast fungus, and CCA1, CNF1, CNF2, CONx1, GPF1, GTA1, MoCOD1 and PCF1 are required for pathogenicity. (prelekara.sk)
Systematic Analysis of ZnCys Transcription Factors Required for Development and Pathogenicity by High-Throughput Gene Knockout in the Rice Blast Fungus. (prelekara.sk)
2007) Genome-wide functional analysis of pathogenicity genes in the rice blast fungus. (prelekara.sk)

2012) MoSwi6, an APSES family transcription factor, interacts with MoMps1 and is required for hyphal and conidial morphogenesis, appressorial function and pathogenicity of Magnaporthe oryzae. (prelekara.sk)
2010) A novel protein Com1 is required for normal conidium morphology and full virulence in Magnaporthe oryzae. (prelekara.sk)

Unusually, the predicted lipase displays ≈ 30% amino acid sequence identity to both feruloyl esterase and lipase of Aspergillus niger . (biomedcentral.com)

For the past few years, research on the pathogenic mechanism of C. cassiicola has mainly focused on biological characteristics, pathogenicity differentiation, cloning of virulence-associated genes, etc. (biomedcentral.com)
We further found via RNA-seq that GPF1 and CNF2 have similar mechanisms in gene expression regulation related to pathogenicity. (prelekara.sk)

molecular characterization of the niad and pyrg genes from penicillium camemberti, and their use as transformation markers. (liverpool.ac.uk)
in this study, the nitrate reductase (niad) and orotidine-5'-monophosphate decarboxylase (pyrg) genes from penicillium camemberti were characterized, and their suitability as metabolic molecular markers for transformation was evaluated. (liverpool.ac.uk)

Survival strategy of the salt-tolerant lactic acid bacterium, Tetragenococcus halophilus , to counteract koji mold, Aspergillus oryzae , in soy sauce brewing. (or.jp)

From garden compost to forest greenery, the mold Aspergillus fumigatus lurks across much of the world. (sciencedaily.com)
The A. fumigatus genome is 28 Mb in size, consisting of 8 chromosomes bearing a total of almost 10,000 genes. (sciencedaily.com)
Nierman and colleagues are now searching these unique genes for clues to A. fumigatus infectivity. (sciencedaily.com)
In other words, A. fumigatus 's virulence genes are likely complex and mixed up with normal metabolic capabilities, Nierman says. (sciencedaily.com)
He and his colleagues now plan to systematically "knock out," or disable, genes that might make A. fumigatus infectious. (sciencedaily.com)

Alkyl citrate biosynthetic gene clusters of the antifungal metabolite sporothriolide 1 were identified from the genomes of the ascomycetes: Hypomontagnella monticulosa MUCL 54604, H. spongiphila CLL 205 and H. submonticulosa DAOMC 242471. (uni-hannover.de)
The biosynthetic gene clusters of these linaridins lack obvious candidate genes for the dehydratase and epimerase required to introduce dehydrobutyrine and D-amino acid residues, respectively. (hokudai.ac.jp)

Based on the nucleotide sequence information of transcripts, we identified 819 novel transcriptionally active regions (nTARs) and revised 906 incorrectly predicted gene models, including revisions of exon-intron structure, gene orientation and sequencing errors. (biomedcentral.com)
Sequence data of the revised genome annotation including several hundreds of novel transcripts, improved gene models and candidate genes for alternative splicing have been made accessible in a comprehensive database. (biomedcentral.com)
The N-terminal amino acid sequence of the enzyme was GSTQSRADAIKAAFSHAWDGYLQY, and sequence analysis indicated that the signal peptide from apnS gene was removed. (elsevierpure.com)
The blocks of A. oryzae -specific sequence are enriched for genes involved in metabolism, particularly those for the synthesis of secondary metabolites. (nature.com)
This suggests that the genome size differences are largely due to sequence acquisition in A. oryzae . (nature.com)
Then, we put the protospacer sequence of a target gene and its protospacer adjacent motif (PAM) behind the start codon "ATG" of DsRed, yielding the non‑functional DsRed (nDsRed) reporter gene, and the nDsRed reporter gene could be rescued after successful targeted editing. (olmdiagnostics.com)
The genome sequence of Acremonium alcalophilum has revealed a large number of genes encoding biomass-degrading enzymes. (biomedcentral.com)
We identified a lipA gene in the genome sequence of Acremonium alcalophilum , encoding a protein with a predicted lipase domain with weak sequence identity to characterized enzymes. (biomedcentral.com)
DEFINITION Vibrio halioticoli IAM 14597 gene for 16S rRNA, partial sequence. (nig.ac.jp)
DEFINITION Sporobolomyces ruber JCM 6884 gene for 18S rRNA, partial sequence. (nig.ac.jp)

Transfers of a single gene, a complete metabolic pathway 10 , whole chromosomes 11 or even cases of the integration of almost complete genomes from bacterial endosymbionts into their eukaryotic hosts 12 have been described. (nature.com)
The two smallest sequenced genomes (A. terreus and P. chrysogenum) do not contain introns in protein-coding genes, whereas the largest genome (T. stipitatus), contains a total of eleven introns. (umd.edu)

Moreover, this method was also applied by targeting the kojic acid synthesis gene kojA, and the transformants with DsRed activity were found to harbor targeted mutations in kojA. (olmdiagnostics.com)

Specific expansion of genes for secretory hydrolytic enzymes, amino acid metabolism and amino acid/sugar uptake transporters supports the idea that A. oryzae is an ideal microorganism for fermentation. (nature.com)

The fused f-msdS gene has been overexpressed in a transformant A. oryzae niaD AM1 cell. (elsevierpure.com)

Then the fused 1,2-α-mannosidase gene (f-msdS) was inserted into the NotI site between P-No8142 and T-agdA in the plasmid pNAN 8142 (9.5 kbp) and thus the Aspergillus oryzae expression plasmid pNAN-AM1 (11.2 kbp) was constructed. (elsevierpure.com)

The resulting data provide new insights into how Zn2Cys6 TF genes regulate important traits during the infection cycle of this rice blast pathogen. (prelekara.sk)

Thousands of putative virulence-associated genes in various pathways or families were identified in C. cassiicola . (biomedcentral.com)

Which genes make the mold virulent? (sciencedaily.com)

However, in the production of fermented foods of soybeans such as soy sauce and miso, Aspergillus sojae is sometimes used instead of A. oryzae. (wikipedia.org)
A. oryzae is also used for the production of rice vinegars. (wikipedia.org)
accumulation of flavoring compounds Color: low production of deferriferrichrome (a siderophore), flavins, and other colored substances Two of the key enzyme groups secreted by A. oryzae are pectinase and peptidase. (wikipedia.org)
A. oryzae secretes a number of salt-tolerant alkaline proteases which makes it particularly stable in the high-sodium conditions required for the production of miso and soy sauce. (wikipedia.org)
Thus, white and black kōji are mainly used in the production of shōchū, but only yellow kōji (A. oryzae) is usually used in the production of sake. (wikipedia.org)
To pave the path towards microbial malic acid production, the potential of acetate as a carbon source for A. oryzae is evaluated in this study. (biomedcentral.com)
A broad acetate concentration range was tested both for growth and malic acid production with A. oryzae . (biomedcentral.com)
This study evaluates relevant aspects of malic acid production with A. oryzae using acetate as carbon source and demonstrates that it is a suitable substrate for biomass formation and acid synthesis. (biomedcentral.com)
The majority of malic acid production processes with A. oryzae described so far utilized glucose as carbon source. (biomedcentral.com)
3. Making Aspergillus oryzae production system antibiotic-free by Sarocha Panchanawaporn (BIOTEC, Thailand). (anmicro.org)
A transformation protocol was established, and genes encoding a fatty acid synthase subunit and a citrate synthase were simultaneously knocked out which led to the loss of sporothriolide and sporochartine production. (uni-hannover.de)
The absence of gene trfkbp12 made the cellulase production in T . reesei more sensitive to the NMD pathway inhibitor. (researchsquare.com)

The gene is localized on the same chromosome at the distance of about 50 kb from telomeric sequences of IL-17A gene, and both genes are in a tail-to-tail orientation [ 3 ]. (hindawi.com)
Distribution and expression of the genes on chromosome 1. (nature.com)

All these findings suggest that the IR of cellulase genes regulates their own gene expression by coupling with the NMD pathway, which might involve the TOR pathway. (researchsquare.com)

Sequencing of the A. oryzae genome was accomplished using the whole-genome shotgun (WGS) approach. (nature.com)
We performed single-cell RNA-sequencing of colon-derived stromal cells and identified distinct classes of fibroblasts with gene signatures that are differentially regulated by chronic inflammation, including IL-11-producing inflammatory fibroblasts. (bvsalud.org)

Moreover, 5′- and 3′-UTR sequences of 4378 genes have been retrieved and alternatively spliced variants of 69 genes have been identified. (biomedcentral.com)

DEFINITION Mus musculus 129SVJ mNB-3 gene for neural recognition molecule NB-3, exon 1 and promoter region. (nig.ac.jp)

Nierman co-authored two additional Aspergillus genome papers in the same issue of Nature. (sciencedaily.com)

The phylogenetic tree has a different topology from published multilocus trees, highlighting the challenges still facing the Aspergillus systematics. (umd.edu)
Generate a phylogenetic tree with phyml with gene structure information produced by GECA that will be visualised by Archeopterix. (inra.fr)

A total of 3288 differentially expressed genes (DEGs) were identified. (biomedcentral.com)

We have successfully elucidated all of the individual enzymatic steps and produced four representative indole diterpenes, paspaline, paxilline, aflatrem, and penitrem, at a yield of ~100 mg/L. These results confirmed that the Aspergillus oryzae expression system is highly reliable for elucidation of biosynthetic pathways, even those involving 17 enzymatic reactions. (heterocycles.jp)

Efficient regulation of bacterial genes in response to the environmental stimulus results in unique gene clusters known as operons. (biomedcentral.com)

It also highlights the importance of HGT in the evolutionary history of CHS and describes bacterial chs genes for the first time. (biomedcentral.com)

We further identify a transcriptional program associated with trans-differentiation of mucosa-associated fibroblasts and define a functional gene signature associated with matrix deposition and remodeling in the inflamed colon. (bvsalud.org)

Wallaby encompasses about 250 predicted genes, some of which are probably involved in competition with microorganisms. (nature.com)
An alternative approach is to use plants as bioreactors, transferring the corresponding genes from microorganisms into plants and producing them at economically acceptable levels [ 8 ]. (biomedcentral.com)
However, it is likely that several horizontal gene transfers (HGT) also occurred in eukaryotic microorganisms and, even more surprisingly, in bacteria. (biomedcentral.com)

In the presence of the NMD pathway inhibitor that successfully repressed the NMD pathway, the mRNA levels of cellulase genes were sharply down-regulated, but the rates of IR in these genes were significantly up-regulated. (researchsquare.com)

The recombinant enzyme expressed in A. oryzae cells was purified to homogeneity in two steps. (elsevierpure.com)

One describes a genome project on Aspergillus oryzae , a nonpathogenic food industry workhorse that has produced sake (rice wine), miso (soybean paste), and shoyu (soy sauce) for 2,000 years. (sciencedaily.com)

Yellow kōji (A. oryzae) is used to produce sake, and at one time all honkaku shōchū. (wikipedia.org)

Most of this variation can be attributed to accessory genes and mobile introns, presumably acquired by horizontal gene transfer of mitochondrial plasmids and intron homing. (umd.edu)

Despite these examples, the lack of specific evolutionary trends in reported cases of lateral gene transfer in eukaryotes has led to the view of ancient, sporadic and isolated events with relatively little global impact on eukaryotic kingdoms, rather than a more frequently and widely occurring phenomenon. (nature.com)

In addition, the NMD pathway inhibitor caused the downregulated mRNA levels of two important genes of the target of rapamycin (TOR) pathway, trfkbp12 and trTOR1 . (researchsquare.com)

Anatomy3

Organisms12

Diseases1

Chemicals and Drugs8

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes7

Disciplines and Occupations1

Technology, Industry, Agriculture2

Information Science3

Nidulans24

Fungi9

Genomic3

Organism1

Species8

Flavus4

Fungal9

Strains2

Heterologous expression3

Biosynthesis3

Proteins6

RIB401

Fungus11

Magnaporthe2

Feruloyl Esterase1

Pathogenicity2

Penicillium2

Koji1

Fumigatus5

Biosynthetic gene clusters2

Sequence10

Genomes2

Transformants1

Fermentation1

NiaD1

Plasmid1

Pathogen1

Virulence1

Mold1

Production12

Chromosome2

Regulates1

Sequencing2

Sequences1

Promoter1

Nierman1

Phylogenetic2

Differentially1

Elucidation1

Clusters1

Bacterial1

Functional1

Microorganisms3

Significantly1

Recombinant1

Sauce1

Sake1

Horizontal gene tra1

Evolutionary1

MRNA1