• Gemfibrozil, sold under the brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. (wikipedia.org)
  • Serum lipids, plasma fibrinogen, whole blood viscosity, plasma viscosity, red cell aggregability and red cell deformability were measured on two baseline samples, separated by 2 weeks of treatment with placebo, and compared with the results obtained after 12 weeks of gemfibrozil (Lopid) 600mg b.d. (iospress.com)
  • It is best not to drink alcohol if you are taking gemfibrozil (Lopid). (camomienoteca.com)
  • Drinking alcohol while taking gemfibrozil (Lopid) can increase your risk of liver problems. (camomienoteca.com)
  • Alcohol can also make gemfibrozil (Lopid) less effective in lowering triglycerides and preventing inflammation of the pancreas. (camomienoteca.com)
  • Lopid is contraindicated in individuals with allergic reaction to gemfibrozil, liver disease, gallbladder disease, severe kidney disease, or when co-administered with repaglinide (Prandin). (buyviagraonliney.com)
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  • Gemfibrozil is contained in the pill Lopid . (allstatins.com)
  • Lopid contains an active ingredient called Gemfibrozil which belongs to a class of drugs called fibrates. (sanfordpharmacy.com)
  • Remember some medicines prevents the full absorption of Lopid as they react with Gemfibrozil . (sanfordpharmacy.com)
  • What is Lopid (Gemfibrozil) prescribed for? (mydrugcenter.com)
  • Generic Lopid ( GEMFIBROZIL ) is a lipid-regulating agent used to lower cholesterol and triglyceride levels in your blood. (rx2go.com)
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  • citation needed] Statin drugs: Concomitant administration of fibrates (including gemfibrozil) with statin drugs increases the risk of muscle cramping, myopathy, and rhabdomyolysis. (wikipedia.org)
  • Gemfibrozil is in a class of lipid-regulating medications called fibrates. (medlineplus.gov)
  • Gemfibrozil belongs to a group of drugs known as fibrates. (familywize.org)
  • Ecotoxicological studies are extensive for gemfibrozil and scarce for other fibrates. (janusinfo.se)
  • Comparative assessment of environmental risk when using the fibrates bezafibrate, fenofibrate and gemfibrozil from a Swedish perspective. (janusinfo.se)
  • Gemfibrozil is a lipid lowering fibrates which increase the low density lipoprotein - cholesterol uptake by the low density lipoprotein - cholesterol receptors. (kembara.co)
  • Gemfibrozil belongs to a class of medicines called fibrates. (mydr.com.au)
  • Fibric acid antilipemic agent that lowers LDL cholesterol more effectively than do older fibrates (ie, clofibrate, gemfibrozil). (medscape.com)
  • Gemfibrozil is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and triglycerides (other fatty substances) in the blood in certain people with very high triglycerides who are at risk of pancreatic disease (conditions affecting the pancreas, a gland that produces fluid to break down food and hormones to control blood sugar). (medlineplus.gov)
  • Gemfibrozil controls high triglycerides and low HDL, but does not cure them. (medlineplus.gov)
  • Gemfibrozil is a lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol, and increases high density lipoprotein (HDL) cholesterol. (nih.gov)
  • While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with gemfibrozil therapy, treatment of patients with elevated triglycerides due to Type IV hyperlipoproteinemia often results in a rise in LDL-cholesterol. (nih.gov)
  • In the primary prevention component of the Helsinki Heart Study, in which 4081 male patients between the ages of 40 and 55 were studied in a randomized, double-blind, placebo-controlled fashion, gemfibrozil therapy was associated with significant reductions in total plasma triglycerides and a significant increase in high density lipoprotein cholesterol. (nih.gov)
  • This subgroup of Type IIb gemfibrozil group patients had a lower mean HDL-cholesterol level at baseline than the Type IIa subgroup that had elevations of LDL-cholesterol and normal plasma triglycerides. (nih.gov)
  • Gemfibrozil is useful in treating patient with low high density lipoprotein, mixed cases of dyslipidemia ( increase in both plasma triglycerides and increase in cholesterol) and prevention of atheroma. (kembara.co)
  • Gemfibrozil works by blocking the absorption of triglycerides from the intestines and increasing the breakdown of fats in the liver. (overnight-us.net)
  • Gemfibrozil is a medication used in the treatment of high levels of cholesterol and triglycerides in the blood. (overnight-us.net)
  • Gemfibrozil works by inhibiting the synthesis of triglycerides in the liver, which reduces the amount of triglycerides in the blood. (overnight-us.net)
  • Aside from reducing cholesterol levels and managing high triglycerides, gemfibrozil can also be used to help lower elevated aminotransferase, an enzyme that otherwise increases the risk of liver problems. (overnight-us.net)
  • We have investigated the rheological effects of gemfibrozil in 50 patients with angiographically documented but stable peripheral occlusive arterial disease. (iospress.com)
  • The net effects of gemfibrozil were to increase mean plasma viscosity, reduce red cell deformability and aggregation and leave native whole blood viscosity unchanged. (iospress.com)
  • The gemfibrozil-statin interaction was studied at the level of active hepatic uptake as a model for such drug-drug interactions. (aspetjournals.org)
  • Gemfibrozil should be avoided to be used with statin as it may lead to severe myositis. (kembara.co)
  • Risk of rhabdomyolysis (muscle injury) increases when gemfibrozil is used with the statin family of cholesterol-reducing medications: pravastatin (Pravachol), lovastatin (Mevacor), rosuvastatin (Crestor), simvastatin (Zocor), fluvastatin (Lescol), and atorvastatin (Lipitor). (buyviagraonliney.com)
  • Gemfibrozil is pill of type Not a Statin while Lipitor is of Statin type. (allstatins.com)
  • Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. (wikipedia.org)
  • Gemfibrozil is a prescription medicine used to treat high cholesterol and triglyceride levels in adults. (overnight-us.net)
  • As a result, gemfibrozil is a valuable treatment option for those seeking to maintain healthy cholesterol and triglyceride levels, as well as improve overall cardiovascular health. (overnight-us.net)
  • The exact way that gemfibrozil works is unclear, however, it is thought to reduce the amount of triglyceride made in the body. (mydr.com.au)
  • if you are taking colestipol (Colestid), take this medication 2 hours before or 2 hours after gemfibrozil. (medlineplus.gov)
  • without knowledge of their own lipid values or double-blind treatment, 60% of patients originally randomized to placebo began therapy with gemfibrozil and 60% of patients originally randomized to gemfibrozil continued medication. (nih.gov)
  • As a long term medication, it is important to lower gemfibrozil cost whenever possible. (familywize.org)
  • Because Gemfibrozil carries a strong risk of interactions with other medications, keep your doctor informed of any changes to your medication schedule. (familywize.org)
  • Pricing is displayed for GEMFIBROZIL , a generic medication. (americaspharmacy.com)
  • Gemfibrozil (GFZ) is a medication of the fibrate category with agonistic effects on PPAR-α and is effective for hypertriglyceridemia and mixed dyslipidemia. (rapamycin.news)
  • Take gemfibrozil at around the same times every day. (medlineplus.gov)
  • Take gemfibrozil exactly as directed. (medlineplus.gov)
  • Continue to take gemfibrozil even if you feel well. (medlineplus.gov)
  • Your doctor will probably tell you not to take gemfibrozil while taking any of these medications. (medlineplus.gov)
  • Your doctor may tell you not to take gemfibrozil. (medlineplus.gov)
  • How do I take Gemfibrozil? (familywize.org)
  • For optimal efficacy, try to take Gemfibrozil at the same time every day. (familywize.org)
  • Do not take Gemfibrozil if you have a history of liver or gall bladder failure. (familywize.org)
  • It is also not known how Gemfibrozil affects unborn fetuses or whether it is transferred into breast milk, so do not take Gemfibrozil if you are pregnant or nursing. (familywize.org)
  • What happens if I take gemfibrozil after I eat? (camomienoteca.com)
  • It is best to take gemfibrozil with the same meals each day, as this helps remind you to take your doses regularly. (camomienoteca.com)
  • In case, you take certain other medications to lower cholesterol like colestipol then take Gemfibrozil 1 hour before. (sanfordpharmacy.com)
  • Hyperlipidemia (Type III) Hypertriglyceridemia (Type IV): Gemfibrozil, though not as effective as niacin (nicotinic acid, a form of Vitamin B3), is better tolerated. (wikipedia.org)
  • Gemfibrozil is used as a therapeutic drug for hyperlipidemia. (phypha.ir)
  • The melting point is 58° - 61°C. Gemfibrozil is a white solid which is stable under ordinary conditions. (nih.gov)
  • The melting point is 58° to 61°C. Gemfibrozil USP is a white or almost white, waxy crystalline solid. (nih.gov)
  • Gemfibrozil increases levels of high density lipoprotein (HDL) subfractions HDL 2 and HDL 3 , as well as apolipoproteins AI and AII. (nih.gov)
  • Moderate reductions in total plasma cholesterol and low density lipoprotein cholesterol were observed for the gemfibrozil treatment group as a whole, but the lipid response was heterogeneous, especially among different Fredrickson types. (nih.gov)
  • Generally gemfibrozil may lead to slight increase in the high density lipoprotein, moderate decrease in low density lipoprotein with marked decreased in plasma very low density lipoprotein. (kembara.co)
  • Typically, when combined with other drugs, such as gemfibrozil, niacin can help to lower levels of harmful low-density lipoprotein (LDL) cholesterol in the blood while raising levels of beneficial high-density lipoprotein (HDL) cholesterol. (overnight-us.net)
  • Gemfibrozil is known to cause allergic reaction in some patients, so contact your doctor immediately if you experience hives, difficulty breathing, or swelling of your face, lips, tongues, or throat. (familywize.org)
  • Gemfibrozil also inhibits the synthesis and increases the clearance of apolipoprotein B, a carrier molecule for VLDL. (wikipedia.org)
  • the mechanism of action is unknown, but gemfibrozil may inhibit lipolysis, the secretion of VLDL, and hepatic fatty acid uptake. (medscape.com)
  • Gemfibrozil will increase the transcription of the gene encoding for the apoprotein apoA1 and apoprotein apoA5 as well as for the lipoprotein lipase. (kembara.co)
  • Gemfibrozil is the generic name for an oral drug used to lower lipid levels. (curecrowd.com)
  • Gemfibrozil comes as a tablet to take by mouth. (medlineplus.gov)
  • Each tablet contains 600 mg gemfibrozil. (nih.gov)
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  • tell your doctor and pharmacist if you are allergic to gemfibrozil, any other medications, or any of the ingredients in gemfibrozil tablets. (medlineplus.gov)
  • Lipazil tablets contain gemfibrozil. (mydr.com.au)
  • In contrast, adding fulvestrant, an Estradiol receptor antagonist, prevents the impact of gemfibrozil on oxidative stress condition, reducing its efficacy to protect the neurons against stress. (phypha.ir)
  • Individuals taking Gemfibrozil or any other prescription medications should talk to their doctors before taking niacin. (overnight-us.net)
  • Gemfibrozil is administered orally, generally taken twice a day. (familywize.org)
  • Gemfibrozil is given orally and gemfibrozil will be excreted via the kidney by metabolizing to glucuronide conjugates. (kembara.co)
  • Lipazil or any other medicine containing gemfibrozil(e.g. (mydr.com.au)
  • Gemfibrozil inhibits the activation of the liver's Cytochrome P450 system and CYP2C8, reducing hepatic metabolism of many drugs, and prolonging their half lives and duration of action. (wikipedia.org)
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  • Gemfibrozil increases HDL subfractions HDL2 and HDL3 as well as apolipoproteins A-I and A-II. (curehunter.com)
  • Gemfibrozil may cause side effects. (medlineplus.gov)
  • What are the possible side effects of taking Gemfibrozil? (familywize.org)
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  • Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's. (rapamycin.news)
  • If you become pregnant while taking gemfibrozil, call your doctor. (medlineplus.gov)
  • It cannot be excluded that gemfibrozil is persistent, due to the lack of data. (janusinfo.se)
  • Gemfibrozil (GFZ) is a relatively persistent pollutant in surface-water environments and it is rather recalcitrant to biological degradation. (unito.it)
  • Gemfibrozil, used for elevated cholesterol, also is reported to cause memory disorders, as are the more commonly used class of cholesterol drugs, the statins. (camomienoteca.com)
  • Recombinant OATP1B1-, OATP2B1-, and OATP1B3-mediated fluvastatin transport was inhibited to 97, 70, and 62% by gemfibrozil (200 μM), respectively, whereas only a small inhibitory effect by gemfibrozil (200 μM) on fluvastatin uptake into primary human hepatocytes was observed (27% inhibition). (aspetjournals.org)
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  • Additionally, gemfibrozil increases levels of HDL ("good") cholesterol in the body, thus further reducing the risk of cardiovascular disease. (overnight-us.net)
  • Results: In gemfibrozil pretreated groups, reduced level of caspase-3 and raised mitochondrial transcription factor A (TFAM) levels were detected. (phypha.ir)
  • Conclusion: Our results indicated the involvement of estradiol receptors in gemfibrozil neuroprotective mechanism, in diminishing oxidative stress-induced damage via reducing caspase-3 and inducing the level of TFAM that plays a crucial role in the mitochondrial biogenesis. (phypha.ir)
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