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  • integrin
  • The α5 integrin subunit and laminin were shown to be localized to the site of dorsal aorta vasculogenesis after lumen formation had commenced. (ubc.ca)
  • Cultrex
  • showing a silver stained gel of multiple lots of Normal (N) and Growth Factor Reduced (R) ECM extracts from our Cultrex BME and a competitor. (amsbio.com)
  • Hydrogels
  • Nevertheless, we have shown that epoxy cross-linkers should be further explored in the fabrication of collagen-based hydrogels, as alternatives to or in conjunction with carbodiimide cross-linkers. (mdpi.com)
  • Matrigel
  • Surprisingly, attempts to define matrix-dependent gene expression profiles by microarray analysis revealed minimal differences between Matrigel- and collagen I-cultured tumor fragments, suggesting that key mRNA differences may be restricted to a minority of cells or that the important alterations are post-translational. (biomedcentral.com)
  • Previous work from the Pearson laboratory [ 5 ] has indicated that fibroblast-dependent remodeling of collagen is key to inducing invasion in mixed cultures of Matrigel/collagen I and that basal, but not luminal, breast cancer cell lines preferentially invade under those conditions. (biomedcentral.com)
  • Cells cultured on the laminin matrices exhibited significantly increased metabolic function relative to cells on Matrigel and human primary hepatocytes. (thescienceroom.com)
  • matrices
  • 14. The composite of claim 12, wherein said encapsulated biologically active agent is in the form of at least one selected from the group consisting of microcapsules, microspheres, microparticles, microfibers, sol gel matrices, and reinforcingfibers. (patentgenius.com)
  • tumor
  • In contrast, identical tumor fragments in a collagen I matrix which resembles the interstitial breast stroma exhibited a pronounced protrusive migration and local dissemination. (biomedcentral.com)
  • whereas
  • Application of the F(ab′) 2 from a monoclonal antibody to ox-LDL revealed a strong competition of the binding of highly ox-LDL to type II collagen (60%), laminin (35%), type I collagen (20%), and poly- d -lysine (15%), whereas the binding to fibronectin was not affected. (ahajournals.org)
  • 9 10 11 As to the influence of the negative charge of ox-LDL on its binding to various types of collagen, one sort of ox-LDL was used in one investigation, 10 whereas in another study the affinity of type I collagen to ox-LDL modified to different degrees was reported. (ahajournals.org)
  • adhesion
  • In addition, improvement of cell proliferation on the surfaces of the materials was observed when neurite promoting laminin epitope, IKVAV, and adhesion peptide, YIGSR, were incorporated. (mdpi.com)
  • polymer
  • The aim of this work was to characterize FN- and LM-based collagen semi-interpenetrating polymer networks (semi-IPNs), in order to understand how these biomacromolecular species can affect collagen network assembly and properties. (springer.com)
  • A bioactive sol-gel solution includes a biocompatible polymer, a gelable inorganic base material, and at least one calcium and phosphorous molecular species. (patentgenius.com)
  • The polymer acts as a viscosity modifier to the sol or gel, increases the viscosity range over which fibers can be sprayed or spun, and broadens the time period over which fibers can be sprayed or spun. (patentgenius.com)
  • Fibers
  • Novel sol-gel bioactive fibers," Journal of Biomedical Materials Research, 55(4):460-467, 2001. (patentgenius.com)
  • Different collagen types form rigid fibers/two-dimensional reticula, allowing solid tissues to withstand stretching. (sigmaaldrich.com)
  • concentrations
  • When studying the influence of Na + , K + , Ca 2+ , Mg 2+ (equivalent to their concentrations in the interstitial fluid), native LDL, moderately ox-LDL, and highly ox-LDL showed the same affinity to type I collagen. (ahajournals.org)
  • In addition, high FN and LM concentrations affected collagen fibre assembly and structure and induced drastic effects on rheological and transport properties. (springer.com)
  • biocompatible
  • Cell experiments demonstrated that the gel is biocompatible, non-cytotoxic and can facilitate cell viability with phenotypic morphology. (ovid.com)
  • presence
  • Phase Behavior and Structural Changes in Tetraethylorthosilicate-Derived Gels in the Presence of Polyethylene Glycol, Studied by Rheological Techniques and Visual Observations," Journal of Colloid and Interface Science, 204:45-52,1998. (patentgenius.com)
  • form
  • A bioactive glass composite can be formed from the bioactive sol-gel solution, including a fibrous form. (patentgenius.com)
  • contains
  • Normally the eye contains a gel-like material called the vitreous that occupies the space between the lens and the retina and allows for unfettered transmission of light. (managedcaremag.com)