Probiotics have long been utilized as functional food and modulate gut microbial homeostasis, but their colonization niche is mostly unclear and transient, which restrains the development of microbiome-targeted strategies. (bvsalud.org)
The microbiome of the human gastrointestinal tract contains 10-100 trillion microbes composed of 500-1000 different species, [ 1 ] with the majority contained in four phyla: Bacteroidetes, Firmicutes, Actinobacteria, and Proteobacteria. (medscape.com)
Benefits from our microbiome include the formation of nutrients and vitamins, energy from short-chain fatty acid production during the metabolism of foodstuffs, breakdown of indigestible dietary fibers, protection from infection through prevention of colonization by pathogenic bacteria, and development of mucosal immunity. (medscape.com)
However, the dynamics of a normal, "healthy" microbiome remain difficult to determine, because each human has a unique pattern of microbes. (medscape.com)
AGPs are thought to operate through modulating the gut microbiome to limit opportunities for colonization by pathogens, increase nutrient utilization, and reduce inflammation. (biomedcentral.com)
Previous studies investigating the effects of AGPs on the poultry gut microbiome have largely focused on 16S rDNA surveys based on a single gastrointestinal (GI) site, diet, and/or timepoint, resulting in an inconsistent view of their impact on community composition. (biomedcentral.com)
These analyses are manifold, and comprehensively integrated with building and urban science to appropriately capture the physical, chemical and biological variables that influence the colonization, succession and function of the urban microbiome. (nih.gov)
Prof. Dai developed computational approaches to study key factors underlying the heterogeneity in microbiome dynamics. (microbiota-site.com)
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes. (jamanetwork.com)
BACKGROUND: Infections with SARS-CoV-2 have a pronounced impact on the gastrointestinal tract and its resident microbiome. (uni.lu)
Here, a comprehensive review of current knowledge about the mycobiome , the collective of fungi within the microbiome , highlights methods for its study, diversity between body sites, and dynamics during human development, health, and disease. (lactobacto.com)
Although the microbiome of the healthy term infant remains poorly understood, more effort has been placed on understanding fungal colonization of preterm infant s. (lactobacto.com)
Microbes6
Sarkis Mazmanian of the California Institute of Technology (Caltech) and his colleagues introduced different species of Bacteriodes into germ-free mice to learn how the microbes competed in the gastrointestinal tract. (nih.gov)
The findings help explain how the bacteria establish and maintain long-term colonization and raise new questions about Bacteroides' interactions with other microbes as well as with the host's tissues. (nih.gov)
For instance, its constant contact with the gastrointestinal microbes and components of the diet makes it a major player within the immune system. (mdpi.com)
Specifically, the colon contains ~10 trillion cells, or 33% of the total bacterial cells in the human body, making it a site with the most microbes compared to other gastrointestinal system sites. (frontiersin.org)
Colonization with mutualistic microbes starts principally at birth when the newborn contacts the bacteria of the birth canal or during maternal and environmental contact after caesarean section, except in pathologic conditions such as intrauterine infection with a pathogen. (biomedcentral.com)
While there has been previous research into disease-related microbes in takahē, little is known about the microbes present in the gastrointestinal tract. (biomedcentral.com)
Pathogens2
However, there is a knowledge gap regarding the colonization dynamics of L. plantarum ZDY2013 in the host intestine and the colonization niche of its interaction with pathogens. (bvsalud.org)
Using a range of dermal and gastrointestinal pathogens ( Leishmania sp. (nih.gov)
Intestinal colonization2
Fig. 3: 5-HT and the SSRI fluoxetine regulate gene expression and intestinal colonization of T. sanguinis . (nature.com)
Initial intestinal colonization in the human infant and immune homeostasis. (jamanetwork.com)
Bacteria2
[ 14 ] Translocation of intact bacteria from the gastrointestinal tract to the portal circulation in patients with cirrhosis can result in bacteremia or spontaneous bacterial peritonitis . (medscape.com)
5. Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and alterations in serum metabolites. (nih.gov)
Alimentary tract1
However, SED has also been reported causing health disorders such as chronic proliferative rhinitis in adult sheep, abortions, testicular lesions in rams or alimentary tract disorders in young animals. (intechopen.com)
Infection3
Thus, patients simultaneously co-colonized with MRSA and VRE are likely at increased risk for colonization or infection by VRSA. (cdc.gov)
However, the complete mechanisms and sets off of phage discharge as well as the dynamics of an infection of gut commensals continues to be poorly known [1,2,7,8]. (mindunwindart.com)
these infants at risk of Candida colonization and infection. (lactobacto.com)
Oral cavity2
Trillions of microorganisms inhabit different parts of the body, such as the skin, gastrointestinal tract, oral cavity, respiratory tract, and urogenital tract. (medicallabnotes.com)
shared their findings in this Research Topic, where they observed specific site-preferable bacterial signatures in the oral cavity and other parts of the gastrointestinal tract. (frontiersin.org)
Respiratory tract1
Several studies performed in abattoirs reported the presence of SED in healthy sheep in the intestinal content and also in the respiratory tract. (intechopen.com)
Microbial3
Here, we collected 123 microbial samples of 11 healthy goat kids and their mothers to investigate the colonization and acquisition of the gut microbiota and their correlations with volatile fatty acids (VFAs) in goat kids from birth to day 56. (frontiersin.org)
These results have important implications for the selection of biopesticides for this species, and highlight the need for greater research into the elegant microbial interactions that may impact host individual and population dynamics. (prelekara.sk)
The spatial heterogeneity of microbial communities has been observed across different habitats, ranging from human gastrointestinal tract to plant rhizosphere. (microbiota-site.com)
Lipid metabolism1
T. sanguinis colonization regulates host lipid metabolism. (nature.com)
Large intestine2
Related diseases of the gastrointestinal system include inflammation of the stomach and large intestine. (wikipedia.org)
However, it is increasingly evident that other sections of the gastrointestinal tract, such as the large intestine (also referred to as the hindgut), are similarly impacted by the same factors. (mdpi.com)
Maternal3
Universal screening at 35--37 weeks' gestation for maternal GBS colonization and use of intrapartum antibiotic prophylaxis has resulted in substantial reductions in the burden of early-onset GBS disease among newborns. (cdc.gov)
Although early-onset GBS disease has become relatively uncommon in recent years, the rates of maternal GBS colonization (and therefore the risk for early-onset GBS disease in the absence of intrapartum antibiotic prophylaxis) remain unchanged since the 1970s. (cdc.gov)
Maternal colonization with GBS in the genitourinary or gastrointestinal tracts is the primary risk factor for disease. (cdc.gov)
Microbiota dynamics1
4. Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. (nih.gov)
Digestion1
It is well established that the functions of the gastrointestinal tract go beyond the digestion and absorption of nutrients. (mdpi.com)
Inflammation3
Eosinophilic enteropathy - a condition where eosinophils build up in the gastrointestinal tract and blood vessels, leading to polyp formation, necrosis, inflammation and ulcers. (wikipedia.org)
citation needed] Inflammation of the gastrointestinal tract is common after treatment with radiation therapy to the abdomen or pelvis. (wikipedia.org)
Mice3
Additionally, the content of L. plantarum ZDY2013 was quantified by qPCR in fecal samples from BALB/c mice, followed by the analysis of its colonization niche preference. (bvsalud.org)
Moreover, L. plantarum ZDY2013 colonization neither damaged the intestine nor ameliorated the damage triggered by B. cereus in BALB/c mice. (bvsalud.org)
Treating T. sanguinis with 5-HT or fluoxetine modulates its competitive colonization in the gastrointestinal tract of antibiotic-treated mice. (nature.com)
Diseases3
Disruptions in this balance, such as alterations in the gut microbiota, have been associated with various health issues, including gastrointestinal disorders , autoimmune diseases , and metabolic disorders . (medicallabnotes.com)
In particular, the diversity and dynamics of the so-called mycobiome , the fungi distributed on and within the body, is poorly understood, particularly in light of the considerable association of fungi with infectious diseases and allergy ( Walsh and Dixon 1996 ). (lactobacto.com)
Human2
Lactiplantibacillus (L.) plantarum ZDY2013 is an allochthonous species of the human gastrointestinal tract with acid-tolerant properties. (bvsalud.org)
Both Reddy and Sledjeski caution that before potential health applications can be developed, tested and approved for human use, more research is needed on the intricacies of microbe-host dynamics. (nih.gov)
Host1
Model organisms make understanding the principles of microbe-host dynamics more feasible,' says Michael Reddy of the National Institutes of Health, which funds myriad microbiota studies. (nih.gov)
In addition, previous studies in this population have been limited by the use of clinical cultures as markers for colonization, which underestimate the true proportion of patients colonized with these resistant organisms ( 13 - 15 ). (cdc.gov)
After successful colonization, S pneumoniae can cause a wide variety of clinical symptoms. (medscape.com)
Composition1
Its colonization showed three distinct phases with dramatic shifts of composition mainly driven by age and diet changes. (frontiersin.org)
Patients4
Hospitalized patients are at increased risk of developing CDI because they are exposed to C. difficile spores through contact with the hospital environment and often receive antibiotics and other medications that can disrupt the integrity of the indigenous intestinal microbiota and impair colonization resistance. (nih.gov)
Patients in the ICU and other critically ill patients are at high risk for co-colonization with MRSA and VRE and, possibly, VRSA, since both organisms are endemic and associated with increased illness severity ( 11 , 12 ). (cdc.gov)
Despite the high risk, epidemiologic risk factors associated with co-colonization by MRSA and VRE in patients admitted to ICUs have not been described. (cdc.gov)
Both AI-2 and ciprofloxacin result in phage discharge, indicating that conditions in the gastrointestinal tract of hospitalized patients treated with antibiotics order Everolimus might lead to distribution of virulence genes to apathogenic enterococci and possibly also to other commensals or even to beneficial probiotic strains. (mindunwindart.com)
Factors1
Some Figure shorter Strikes and lower levels, factors declining longer tracts and higher players. (wirthig.eu)
Hospital1
We report a high prevalence of VRE/MRSA co-colonization upon admission to ICUs at a tertiary-care hospital. (cdc.gov)