• Diffuse large B-cell lymphomas of the stomach are primarily treated with chemotherapy with CHOP (cyclophosphamide+doxorubicine+vincristine+prednisone) with or without rituximab being a usual first choice. (wikipedia.org)
  • Plasmablastic lymphoma was first reported in 1997, when a series of sixteen diffuse large B-cell lymphomas with unique immunohistochemistry were presented in HIV-positive patients with predominant involvement of the oral cavity [ 3 ]. (hindawi.com)
  • Radiation treatment for H. pylori-negative gastric malt lymphoma, has a high success rate, 90% or better after 5 years. (wikipedia.org)
  • Nonetheless, we can loosely use H pylori prevalence as a surrogate for the worldwide prevalence of gastric MALT lymphoma. (medscape.com)
  • Marginal zone lymphoma or mucosa-associated lymphoid tissue (MALT) lymphoma (MALToma) is acquired secondary to persistent antigenic stimulation with either chronic infectious conditions or autoimmune processes, such as H pylori gastritis, Hashimoto thyroiditis, and Sjögren syndrome. (medscape.com)
  • MALT lymphoma develops as marginal zone memory B cells undergo somatic mutation and replace the normal B cell population. (medscape.com)
  • This study assessed the value of morphological grading and the expression of the co-stimulatory markers CD40, CD80 and CD86 and their ligands to predict clinical outcome in 23 consecutive low-grade MALT lymphoma patients treated with H. pylori eradication. (nih.gov)
  • In order to evaluate the parameters that influence the infiltration of the lymph nodes we retrospectively investigated 145 surgical specimens with gastric MALT lymphoma. (nih.gov)
  • 최근의 메타 분석에서는 제균 치료가 약 75%의 위의 low grade MALT lymphoma 환자들에서 조직학적으로 완전 관해(complete histologic remission)를 유발한다고 보고된 바 있다[ 5 ].제균치료에 반응하지 않는 경우, 방사선 요법이나 전신 항암 화학 요법 등을 고려하게 되며, 일부에서는 경과 관찰만 시행하기도 한다. (helicojournal.org)
  • In this report, we describe two cases of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) of the stomach, which presented with multiple small, whitish nodules in the gastric body. (elsevierpure.com)
  • These cases indicate that, although infrequent, gastric MALT lymphoma can show a nodular appearance resembling that of follicular gastritis. (elsevierpure.com)
  • This long-term, retrospective, single-center study evaluated real-world clinical outcomes of gastric mucosa -associated lymphoid tissue (MALT) lymphoma using different therapeutic modalities and analyzed factors affecting survival outcomes and long-term prognosis . (bvsalud.org)
  • We enrolled 203 patients with pathologically confirmed low-grade gastric MALT lymphoma and examined their treatment responses. (bvsalud.org)
  • HPI eradication treatment should be the first-line treatment for patients with localized stage HPI-positive gastric MALT lymphoma . (bvsalud.org)
  • High incidence of other neoplasms in patients with low-grade gastric MALT lymphoma. (pacificejournals.com)
  • Other cancers in patients with gastric MALT lymphoma. (pacificejournals.com)
  • Incidence of second neoplasms in patients with MALT lymphoma: no increase in risk above the background population. (pacificejournals.com)
  • Gastric MALT lymphoma is etiopathologically related to chronic H. pylori infection. (revistagastroenterologiamexico.org)
  • Zucca E, Bertoni F. The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance. (medscape.com)
  • Protease activity of the API2-MALT1 fusion oncoprotein in MALT lymphoma development and treatment. (medscape.com)
  • I still have the Malt Lymphoma / stomach after the H-pylori was treated with antibiotic. (cancer.org)
  • Hello Fibroleo, I was diagnosed with MALT Lymphoma 3 years ago. (cancer.org)
  • It is known that the mandatory initial therapy for local stages of Hp-positive MALT lymphoma of the stomach is the eradication of Hp. (intechopen.com)
  • In 2023, it is estimated that 26,500 Americans will be diagnosed with gastric cancer and 11,130 will die of it. (oncolink.org)
  • Two-thirds of people diagnosed with gastric cancer are older than 66 years. (oncolink.org)
  • More than 27,000 Americans are diagnosed with gastric cancer annually [8] . (mystateline.com)
  • Marginal zone lymphomas are indolent lymphomas that arise from memory B cells in the marginal zone of secondary lymphoid follicles. (medscape.com)
  • Extranodal marginal zone lymphomas commonly follow immune system dysregulation from sustained stimulation with chronic infections or autoimmune disorders. (medscape.com)
  • Risk of second malignancies in patients with gastric marginal zone lymphomas of mucosa associate lymphoid tissue (MALT). (pacificejournals.com)
  • Lymphoma occurs if cancer forms in the lymphatic system. (healthline.com)
  • People with Hodgkin's lymphoma have large cancer cells called Reed-Sternberg (RS) cells. (healthline.com)
  • High levels in the blood may be a sign of cancer, including lymphoma, but could also be due to other sources of inflammation. (healthline.com)
  • Complete remission after H. pylori eradication has been described in low-grade MALT lymphomas as well as in high-grade MALT lymphomas in both immune-competent and AIDS patients, without the use of anti-cancer chemotherapeutic agents. (revistagastroenterologiamexico.org)
  • The National Cancer Institute's Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J. (medscape.com)
  • For stomach (gastric) cancer, there is no standard or routine screening test for the general U.S. population. (oncolink.org)
  • Review the evidence on the benefits and harms of screening for gastric cancer using barium-meal photofluorography, gastric endoscopy, or serum pepsinogen in this expert-reviewed summary. (oncolink.org)
  • Based on fair evidence, screening with barium-meal photofluorography or serum pepsinogen would not result in a decrease in mortality from gastric cancer in areas with relatively low incidence of the disease, such as the United States. (oncolink.org)
  • Evidence from case-control and cohort studies from East Asia are generally consistent with a substantial reduction in gastric cancer mortality associated with endoscopic screening. (oncolink.org)
  • No impact of repeated endoscopic screens on gastric cancer mortality in a prospectively followed Chinese population at high risk. (oncolink.org)
  • Accuracy of screening for gastric cancer using serum pepsinogen concentrations. (oncolink.org)
  • Screening for gastric cancer in Asia: current evidence and practice. (oncolink.org)
  • Gastric cancer is the fourth most common cause of cancer mortality in the world. (oncolink.org)
  • Gastric cancer is a major cause of death worldwide. (oncolink.org)
  • H pylori can also sometimes lead to stomach cancer or a rare type of stomach lymphoma. (medlineplus.gov)
  • 1) Background: Saudi Arabia (SA) is a country with a low incidence of gastric cancer (GC). (mdpi.com)
  • H. pylori, a bacteria that resides in the stomach, has been associated with gastric cancer and a form of lymphoma. (time.com)
  • On the basis of Application , the Global Tissue Diagnostic Market is studied across Breast Cancer, Gastric Cancer, Lymphoma, Non Small Cell Lung Cancer, and Prostate Cancer. (prnewswire.com)
  • Removal of the tumor, often with removal of the surrounding lymph nodes, is the only curative treatment for various forms of gastric (stomach) cancer. (surgeryencyclopedia.com)
  • Adenocarcinomas are by far the most common form of stomach cancer and are less curable than the relatively uncommon lymphomas, for which gastrectomy offers good chances of survival. (surgeryencyclopedia.com)
  • Gastrectomy for gastric cancer is almost always done using the traditional open surgery technique, which requires a wide incision to open the abdomen. (surgeryencyclopedia.com)
  • Certain gene mutations can cause family cancer syndromes, such as Lynch syndrome or hereditary diffuse gastric cancer , that increase your risk of stomach cancer and other cancers. (healthline.com)
  • According to a 2020 review , less than 3% of stomach cancers are caused by a family cancer syndrome called hereditary diffuse gastric cancer. (healthline.com)
  • Men with hereditary diffuse gastric cancer have up to a 70% chance of developing stomach cancer before age 80, and women have as high as a 56% chance. (healthline.com)
  • If one of your parents has hereditary diffuse gastric cancer, you have a 50% chance of having it too. (healthline.com)
  • title=Staging and surgical approaches in gastric cancer: a clinical practice guideline. (wikidoc.org)
  • title=Primary gastric lymphoma versus gastric cancer. (wikidoc.org)
  • Current EPR priorities to improve these estimates include establishing the population attributable burden of HIV to cancer (e.g. cervical cancer, Kaposi sarcoma, non-Hodgkin lymphoma, anal cancer) and of Epstein-Barr virus to non-Hodgkin lymphoma and gastric carcinoma. (who.int)
  • In anticipation of results from ongoing research (the HELPER trial), which is expected to establish the efficacy of testing and treatment of H. pylori in reducing gastric cancer incidence, EPR is expanding research into the implementation of such programmes in LMICs, both by undertaking operational research in programmatic settings in LMICs and by leveraging expertise in modelling the natural history of carcinogenic infections. (who.int)
  • The identification of new obesity-related cancer sites will and diffuse large B-cell lymphoma. (who.int)
  • It has been associated with increased risk of non-Hodgkin lymphoma (NHL) in multiple epidemiologic studies, with some evidence for association with cancer at other sites. (cdc.gov)
  • Conversely, in the highest quartiles, there was an elevated risk of gastric cancer (RR = 2.3, 95% CI:1.1-5.2, p-trend = 0.03) and a suggestion of elevated risk of brain cancer (RR = 2.3, 95% CI: 0.9-5.7, p-trend = 0.31). (cdc.gov)
  • The increased risk of gastric cancer is noteworthy but supporting data are limited. (cdc.gov)
  • About 80% of MALT lymphomas completely regress with eradication therapy. (wikipedia.org)
  • Sometimes, it's hard to differentiate poorly differentiated high grade B-cell gastric lymphoma from gastric adenocarcinoma clinically or radiologically, yet histopathology with immunohistochemistry is recommended to stain specific markers on the malignant cell that favor the diagnosis of lymphoma. (wikipedia.org)
  • Diagnosis and management of rare gastrointestinal lymphomas. (nih.gov)
  • A doctor will carry out several tests to confirm a non-Hodgkin's lymphoma diagnosis. (healthline.com)
  • A lymphoma diagnosis often includes imaging tests. (healthline.com)
  • Yang Y, Yang Y, Yan S. Risk and survival of second primary malignancies following diagnosis of gastric mucosa-associated lymphoid tissue lymphomas: A population-based study. (pacificejournals.com)
  • Fine-needle aspirate is sufficient for lymphoma diagnosis but rarely adequate for subtyping, thus excisional or incisional biopsy is considered mandatory[5]. (oncolink.org)
  • Large, monomorphic, multinucleated neoplastic cells containing abundant cytoplasm and scattered pleomorphic cells were also noted, leading to the diagnosis of tibial plasmablastic lymphoma. (hindawi.com)
  • Biopsy was conducted from the right tibia at a primary care hospital in Larkana four months prior to presenting at Indus Hospital, and histopathological analysis confirmed a diagnosis of plasmablastic lymphoma. (hindawi.com)
  • Several endoscopic findings have been reported, including solitary ulcers, thickened gastric folds, mass lesions and nodules. (wikipedia.org)
  • Malignant blast cells (i.e. diffuse large B-cell lymphoma) are fast-growing and result in aggressive disease, whereas malignant mature lymphocytes (i.e. follicular lymphoma) behave indolently. (oncolink.org)
  • Radhi JM, Ibrahiem K, al-Tweigeri TJ: Soft tissue malignant lymphoma at sites of previous surgery. (karger.com)
  • Ito H, Shimizu A: Malignant lymphoma at the site of a total hip replacement. (karger.com)
  • Syed AA, Agarwal M, Fenelon G, Toner M: Osseous malignant non-Hodgkin's B-cell lymphoma associated with total hip replacement. (karger.com)
  • Only patients with early-stage gastric cancers or those whose surgery is intended only for palliation (pain and symptomatic relief rather than cure) are considered for this minimally invasive technique. (surgeryencyclopedia.com)
  • MALT (mucosa-associated lymphoid tissue) lymphoma (MALToma) is the term traditionally coined for extranodal marginal zone lymphoma of MALT. (medscape.com)
  • Extranodal marginal zone lymphoma develops from mucosa-associated lymphoid tissue (MALT) secondary to chronic antigenic stimulation. (medscape.com)
  • The spread of primary gastric non-Hodgkin's lymphomas of the mucosa-associated lymphoid tissue (MALT) to the perigastric lymph nodes is a very important step concerning the prognosis of these tumours. (nih.gov)
  • This could contribute to the explanation as to why the so-called early lymphomas with an infiltration limited to mucosa and submucosa have a much better prognosis than more advanced tumours. (nih.gov)
  • 위 MALT 림프종(low grade mucosa-associated lymphoid tissue lymphoma)은 결절외 변연부 림프종(extranodal marginal zone lymphoma)의 하나로 B세포 림프종의 5~8%를 차지하며 원발성 위 림프종 중에서는 가장 흔한 암종이다[ 1 , 2 ]. (helicojournal.org)
  • Long-term clinical outcomes of gastric mucosa-associated lymphoid tissue lymphoma in real-world experience. (bvsalud.org)
  • Gastric marginal zone lymphoma of mucosa-associated lymphoid tissue (MZL) shows a higher risk of developing a second primary malignancy and exhibits inferior overall survival. (pacificejournals.com)
  • Second primary malignancies in patients treated for gastric mucosa-associated lymphoid tissue lymphoma. (pacificejournals.com)
  • Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity. (medscape.com)
  • Mucosa-associated lymphoid tissue lymphoma of the stomach: long term outcome after local treatment. (medscape.com)
  • Extranodal marginal zone B-cell lymphomas (mucosa-associated lymphoid tissue [MALT] lymphomas) of the gastrointestinal tract have been known to have characteristic chromosomal aberrations including trisomies of chromosomes 3, 12, and 18. (uninsubria.it)
  • The gastrobiopsy material of 115 patients with lymphoid cell infiltrates in the gastric mucosa was studied, a complex of morphological diagnostic criteria for MALT gastric lymphoma for gastrobiopsy was developed based on a combination of histological and immunohistochemical characteristics of tumor cells, the nature of their growth. (intechopen.com)
  • The two most common types of lymphoma that develop in your stomach are called mucosa-associated lymphoid tissue gastric lymphoma and diffuse large B-cell lymphoma . (healthline.com)
  • It is also the most common source of lymphomas in the gastrointestinal tract. (wikipedia.org)
  • [ 1 ] In contrast, extranodal marginal zone lymphoma outside the gastrointestinal tract (eg, salivary glands, ocular adnexa, thyroid gland) is more likely to spread, with gastric involvement reported in up to 30% of patients. (medscape.com)
  • CT features of peripheral T-cell lymphoma in the gastrointestinal tract in Chinese population and literature review. (nih.gov)
  • Distinguishing poorly differentiated gastric lymphoma from adenocarcinoma is essential because the prognosis and modalities of treatment differ significantly. (wikipedia.org)
  • These lymphomas are difficult to differentiate from gastric adenocarcinoma. (wikipedia.org)
  • Distinguishing the common adenocarcinoma from the uncommon lymphoma may sometimes be difficult, but it is important because of major differences in staging, treatment, and prognosis. (oncolink.org)
  • Gastric MALToma symptoms may mimic those of peptic ulcer disease or gastritis. (medscape.com)
  • A peptic ulcer is an open sore or raw area in the lining of the stomach (gastric) or the upper part of the small intestine (duodenal). (mountsinai.org)
  • While the vast majority of peptic ulcers (gastric ulcers in the stomach or duodenal ulcers in the duodenum) are managed with medication, partial gastrectomy is sometimes required for peptic ulcer patients who have complications. (surgeryencyclopedia.com)
  • Chronic inflammation of MALT from infective or autoimmune disorders can lead to the development of extranodal marginal zone B-cell lymphomas, or MALTomas. (medscape.com)
  • Gastrosplenic fistula formation resulting from primary gastric malignancy is rare and should be managed as a matter of emergency. (gazi.edu.tr)
  • We present a case of an adolescent with NBS who presented with persistent abdominal pain, and was ultimately diagnosed with a primary gastric malignancy. (biomedcentral.com)
  • Gastrointestinal diseases (including gastric ulcers) affect an estimated 25-30% of the world's population. (surgeryencyclopedia.com)
  • For duodenal ulcers, antrectomy may be combined with other surgical procedures that are aimed at reducing the secretion of gastric acid, which is associated with ulcer formation. (surgeryencyclopedia.com)
  • The stomach is a common site of origin for GI hemorrhage, with gastric ulcers being the most common cause. (tuftscatnip.com)
  • Extranodal variants of MALT lymphomas can occur in any organ due to chronic antigenic stimulation. (intechopen.com)
  • Conclusion The index case highlights an exceedingly rare association of gastric MZL with testicular mixed germ cell tumour with rare age presentation. (pacificejournals.com)
  • We report a patient who was diagnosed with primary non-Hodgkin's lymphoma and who underwent surgical treatment for gastrosplenic fistula. (gazi.edu.tr)
  • These tumors may range from well-differentiated, superficial involvements (MALT) to high-grade, large-cell lymphomas. (wikipedia.org)
  • Throughout the GI tract, tumors are mostly commonly found in the small intestine (55%) and colon (33%) Footnote 2 .While lymphoma represents about half of GI malignancies, non-Hodgkin are the predominant pathology with one study finding Burkitt lymphoma comprising 53% of GI tumors and other types of non-Hodgkin lymphoma accounting for 43% [ 1 , 2 ]. (biomedcentral.com)
  • In cats, tumors of the stomach are the most common cause of gastric bleeding. (tuftscatnip.com)
  • These include gastric carcinomas, lymphoma and mast cell tumors. (tuftscatnip.com)
  • Thus, surgeons, radiologists and pathologists should be aware of considering the differential of non-lymphoid malignancy at the distant site apart from the systemic spread of primary extranodal non-Hodgkin lymphoma. (pacificejournals.com)
  • Primary gastric lymphoma (lymphoma that originates in the stomach itself) is an uncommon condition, accounting for less than 15% of gastric malignancies and about 2% of all lymphomas. (wikipedia.org)
  • Primary gastric malignancies are exceedingly rare in pediatric patients and not typically high on the differential of abdominal pain. (biomedcentral.com)
  • Non-Hodgkin lymphoma (NHL) represents a heterogeneous group of malignancies of different biology and prognosis. (medscape.com)
  • [ 19 ] The true incidence of gastric MALToma worldwide remains unclear, because the presenting symptoms are nonspecific and endoscopy findings often mimic gastritis. (medscape.com)
  • [ 26 ] the incidence of gastric marginal zone lymphoma is nearly equal among men and women-except at older ages in whom the incidence is higher among males (male-to-female incidence rate ratio = 1.27). (medscape.com)
  • NCCN Clinical Practice Guidelines in Oncology: B-Cell Lymphomas, Version 5.2021. (medscape.com)
  • However, knowledge of the clinical significance of cytogenetic changes in MALT lymphomas is still limited. (uninsubria.it)
  • The Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J.{Ref 1} In 1994, the Revised European-American Lymphoma (REAL) classification attempted to apply immunophenotypic and genetic features in identifying distinct clinicopathologic NHL entities. (medscape.com)
  • He has a history of diffuse large B-cell lymphoma that was diagnosed at age eight during a hospitalization for pneumonia and pleural effusion. (biomedcentral.com)
  • Enteropathy-type T-cell lymphoma. (nih.gov)
  • Background: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease and the most common gastrointestinal lymphoma. (fujita-hu.ac.jp)
  • 2 According to histologic subtype, diffuse large B-cell lymphoma (DLBCL) and Burkitt's lymphoma are the most common forms of NHL. (revistagastroenterologiamexico.org)
  • Initially considered a variation of diffuse large B-cell lymphoma (DLBCL), PBL was later classified as a distinctive mature B-cell lymphoma and separated from the class of DLBCL by WHO [ 1 ]. (hindawi.com)
  • Herein, we describe the case of a 76-year-old man who developed diffuse large B cell lymphoma in the tibia 3 years after total knee arthroplasty for osteoarthritis. (karger.com)
  • Lima FP, Bousquet M, Gomez-Brouchet A, de Paiva GR, Amstalden EM, Soares FA, Dastugue N, Vassallo J, Brousset P: Primary diffuse large B-cell lymphoma of bone displays preferential rearrangements of the c-MYC or BCL2 gene. (karger.com)
  • Cheuk W, Chan AC, Chan JK, Lau GT, Chan VN, Yiu HH: Metallic implant-associated lymphoma: a distinct subgroup of large B-cell lymphoma related to pyothorax-associated lymphoma? (karger.com)
  • Ganapathi M, Lake DN, Griffiths AP: Periprosthetic high-grade B-cell lymphoma complicating an infected revision total hip arthroplasty. (karger.com)
  • Management of non-Hodgkin lymphomas arising at extranodal sites. (nih.gov)
  • The belief that T-cell lymphomas have a worse prognosis than B-cell lymphomas remains controversial. (oncolink.org)
  • The prognostic/predictive indicators among patients with gastric and intestinal DLBCL (giDLBCL) are controversial beyond their anatomical sites. (fujita-hu.ac.jp)
  • Methods: This retrospective study included 174 patients with primary gastric (n = 129) or intestinal (n = 45) DLBCL treated with rituximab-containing chemotherapy between 1995 and 2018. (fujita-hu.ac.jp)
  • Second line therapy for MALT lymphomas is usually chemotherapy with a single agent, and complete response rates of greater than 70% have been reported. (wikipedia.org)
  • Subtotal gastrectomy, with post-operative chemotherapy is undertaken in refractory cases, or in the setting of complications, including gastric outlet obstruction. (wikipedia.org)
  • Most cases of lymphoma are usually considered treatable. (healthline.com)
  • A review of the literature has identified 11 other cases of lymphoma arising in the context of orthopaedic metallic implants. (karger.com)
  • In this study, we sought to assess the epidemiology of GC, its clinicopathological profiles, and its association with risk factors as well as to identify premalignant gastric lesions (PGL) and examine neoplastic progression. (mdpi.com)
  • Conclusions IEE findings of the gastric corpus differed between H. pylori -associated and autoimmune gastritis, suggesting different pathogenesis of the two diseases. (thieme-connect.com)
  • Our data thus support the thesis that gastric MALT lymphomas show clinicopathologic similarities with gastric carcinomas. (nih.gov)
  • The Non-Hodgkin's lymphomas (NHL) comprise a diverse collection of lymphoreticular neoplasms, usually but not necessarily arising in nodal tissue. (oncolink.org)
  • A rare, extranodal T-cell non-Hodgkin lymphoma that arises from the stomach with the bulk of the mass located in the stomach. (nih.gov)
  • Gastrointestinal non-Hodgkin lymphomas. (nih.gov)
  • REAL/WHO- [6] - classification includes leukemias and lymphomas, with 3 categories based on lineage and morphology (Hodgkin, B cell, and T/NK cell). (oncolink.org)
  • Plasmablastic lymphoma is an aggressive, high-grade non-Hodgkin lymphoma predominantly seen in HIV-infected individuals. (hindawi.com)
  • MALToma) is the most common indolent subtype representing 7%-8% of all B-cell lymphomas, and as many as 50% of primary gastric lymphomas. (medscape.com)
  • A low white blood cell count can occur due to lymphoma or other conditions, like an autoimmune disorder. (healthline.com)
  • Various molecular events involving chromosome 3 may be related to the pathogenesis of this group of lymphomas. (hku.hk)
  • In addition, we found gains of the X chromosome in 36.4% of MALT lymphomas, in 34.5% of ex-MALT DLBCLs, and in 36.4% of de novo DLBCLs. (uninsubria.it)
  • An unexpected high and previously unreported gain of chromosome X in gastric MALT lymphomas was found. (uninsubria.it)
  • Our data further support the notion that the depth of infiltration is a very important prognostic factor in MALT lymphomas. (nih.gov)
  • Inflammation resulting from acid reflux is usually treated by administering drugs that suppress gastric acid secretion, as well as drugs that form a protective barrier on the ulcer and foster more rapid healing. (tuftscatnip.com)
  • 68 patients with stages I - II of gastric MALT lymphomas were observed. (intechopen.com)
  • Ils ont été répartis en deux groupes : 12 patients souffrant d'une thrombocytopénie à médiation immunitaire (groupe 1) et 12 patients atteints d'une thrombocytopénie à médiation non immunitaire (groupe 2). (who.int)