• Colorectal cancer. (aiom.it)
  • Between the first results of EPIC , the finding of the association between fibre intake and reduced colorectal cancer risk is of great scientific importance, since other cohorts questioned the potential protective effect of fibre (3) . (aprifel.com)
  • Two other results that support the potential beneficial effect of plant foods against colorectal cancer are the protective effect of fruit and vegetables observed in preliminary analyses (4) and the significant inverse association between nut and seed intake observed for colon cancer in women (5) . (aprifel.com)
  • This study explored the expression of Ln5 and the role of its relationships with PTEN, phospho-EGFR (p-EGFR) and phospho-Akt (p-Akt) in the prognosis of patients with non-small cell lung cancer (NSCLC). (spandidos-publications.com)
  • The two studies that follow are for people with non-small cell lung cancer (NSCLC) - locally advanced, unresectable or metastatic NSCLC and stage I NSCLC, respectively. (providence.org)
  • Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80-85% of all cases. (providence.org)
  • However, over half of all people with newly diagnosed NSCLC have stage IV cancer (cancer that has spread outside the lung where it started to other areas in the body). (providence.org)
  • Non-small cell lung carcinoma (NSCLC). (aiom.it)
  • Moreover, excision repair cross-complementing group 1 gene ( ERCC1 ) rs3212986 GG homozygosity and rs11615 T allele were associated with a higher risk of developing non-small cell lung cancer (NSCLC) in the Polish population [ 10 ]. (jcancer.org)
  • INDIANAPOLIS, May 29, 2020 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced that the U.S. Food and Drug Administration (FDA) has approved CYRAMZA(® )(ramucirumab injection, 10 mg/mL solution), in combination with erlotinib, for the first-line treatment of people with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) mutations. (epicos.com)
  • The first was REVEL, which supported the approval of CYRAMZA plus docetaxel as a treatment for people with metastatic NSCLC whose cancer has progressed after prior platinum-based chemotherapy. (epicos.com)
  • Recent studies have shown that pyroptosis-related genes are associated with the prognosis of cancer patients. (nature.com)
  • 3 ] found that a pyroptosis-related signature can effectively predict the prognosis of patients with ovarian cancer. (nature.com)
  • One reason may be that claudin 18 positivity may be associated with a better prognosis for patients with diffuse gastric cancer, he explained. (medscape.com)
  • First-line therapy for HER2− mG/GEJ adenocarcinoma generally consists of chemotherapy and immunotherapy, but among patients with advanced disease, the prognosis continues to be poor, and therapeutic options are limited. (medscape.com)
  • Methods A multi-factorial evaluation could provide more objective utility, particularly for either prediction and/or prognosis of gastric cancer. (researchsquare.com)
  • The prognosis for people with lung cancer generally depends on the stage at which cancer is detected. (providence.org)
  • Background: Vestigial like family member 3 (VGLL3) is associated with the prognosis of epithelial ovarian cancer and soft tissue sarcoma, but its role in gastric cancer (GC) is unclear. (researchgate.net)
  • SNPs in genes encoding proteins involved in DNA damage repair pathways are associated with the risk and prognosis of various cancers, including lung cancer. (jcancer.org)
  • It has a better prognosis than traditional ductal adenocarcinoma. (msdmanuals.com)
  • The first study is for people with locally advanced or metastatic gastric, gastroesophageal junction (GEJ) and esophageal adenocarcinoma. (providence.org)
  • The trial is currently enrolling people with locally advanced or metastatic gastric, GEJ and esophageal adenocarcinoma that can't be surgically removed. (providence.org)
  • On January 15, 2021, the Food and Drug Administration approved fam-trastuzumab deruxtecan-nxki (Enhertu, Daiichi Sankyo) for adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen. (ecancer.org)
  • Efficacy was evaluated in a multicenter, open-label, randomised trial (DESTINY-Gastric01, NCT03329690) in patients with HER2-positive locally advanced or metastatic gastric or GEJ adenocarcinoma who had progressed on at least two prior regimens, including trastuzumab, a fluoropyrimidine- and a platinum-containing chemotherapy. (ecancer.org)
  • Today's approval underscores Lilly's continued commitment to people living with lung cancer and to delivering meaningful medicines that are tailored for those with advanced or metastatic cancers. (epicos.com)
  • It also further reinforces the value that CYRAMZA can provide in treating certain advanced or metastatic cancers. (epicos.com)
  • 1 ] Breast carcinoma is the most common cause of cutaneous metastasis, followed by carcinoma large intestine, lung, and ovaries in women. (lww.com)
  • Histopathology of peripheral nerve and sympathetic ganglion from a patient with autonomic failure, oat-cell carcinoma of the lung, and positive anti-HU antibody titer. (medscape.com)
  • HPV-associated cancers include microscopically confirmed carcinoma of the cervix and squamous cell carcinomas of the vagina, vulva, penis, anus, rectum, and oropharynx. (cdc.gov)
  • HPV-associated cancers include microscopically confirmed carcinoma of the cervix and squamous cell carcinomas of the vagina, vulva, penis, anus (including rectal squamous cell carcinoma), and oropharynx. (cdc.gov)
  • Typically, clear cell renal cell carcinoma (CCRCC) is the most important tissue subtype of renal cancer, accounting for 80% of all cases [ 4 ]. (biomedcentral.com)
  • Esophageal adenocarcinoma or squamous cell carcinoma. (aiom.it)
  • This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignature® test status. (ucbraid.org)
  • This phase II trial studies how well Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor AZD6738 works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma (RCC), urothelial carcinoma, all pancreatic cancers, endometrial cancer, and other solid tumors excluding clear cell ovarian cancer that have spread to nearby tissue or lymph nodes or other parts of the body. (ucbraid.org)
  • Decreased PKP2 and PKP3 may be early prognostic markers and loss of PKP3 expression during gastric carcinoma progression may indicate an invasive phenotype. (biomedcentral.com)
  • RARA is altered in 1.69% of all cancers with breast invasive ductal carcinoma, lung adenocarcinoma, colon adenocarcinoma, esophageal adenocarcinoma, and invasive breast carcinoma having the greatest prevalence of alterations [ 3 ]. (mycancergenome.org)
  • Acinar cell carcinoma is a rare cause of pancreatic cancer. (msdmanuals.com)
  • Even though developed for AML patients, our pan-cancer analyses demonstrate a wider application of the IPRP signature for prognostic prediction and analysis of tumor-immune interplay also in multiple solid tumors. (nature.com)
  • This phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or urothelial cancer that has spread to other places in the body (advanced). (ucbraid.org)
  • Combining BAY 1895344 with chemotherapy treatment (cisplatin, or cisplatin and gemcitabine) may be effective for the treatment of advanced solid tumors, including urothelial cancer. (ucbraid.org)
  • We used immunohistochemistry to detect OPN in a selection of 350 human tumors and 113 normal tissues, from a variety of body sites, using stage-oriented human cancer tissue arrays. (aacrjournals.org)
  • Although OPN expression was identified in a good number of bladder, prostate, and brain tumors, the majority of 6 skin cancers, 11 of 14 salivary gland cancers, 2 thyroid carcinomas, and 23 of 26 breast cancers revealed low OPN positivity or were negative. (aacrjournals.org)
  • Lung cancer is one of the common malignant tumors in the world, and it remains the leading cause of cancer mortality because of its high malignant and metastatic potential [ 1 ]. (jcancer.org)
  • Most pancreatic cancers are exocrine tumors that develop from ductal and acinar cells. (msdmanuals.com)
  • By the time of diagnosis, 90% of patients have locally advanced tumors that have involved retroperitoneal structures, spread to regional lymph nodes, or metastasized to the liver or lung. (msdmanuals.com)
  • But more than that, it also detected the relationship between leisure time exercises with 10 other types of cancer including esophageal adenocarcinoma, liver cancer, cancer of the gastric cardia, kidney cancer, and myeloid leukemia. (newhopemedicalcenter.com)
  • Due to the unobvious early symptoms and the influence of some adverse factors such as tumor heterogeneity and low immunogenicity, patients with advanced gastric cancer (AGC) cannot benefit significantly from treatments such as radical surgical resection, radiotherapy, chemotherapy, and targeted therapy. (frontiersin.org)
  • Gastric cancer (GC) is a common malignant tumor originating from gastric mucosa epithelial cells, and its onset is relatively insidious. (frontiersin.org)
  • Zolbetuximab is a monoclonal antibody that targets the cell surface molecule CLDN18.2, which is expressed in normal gastric mucosa cells and is retained in mG/GEJ tumor cells. (medscape.com)
  • A total of 98 tissue samples were obtained from the tumor bank of Guangdong Lung Cancer Institute (Guangzhou, China) between 2004 and 2006. (spandidos-publications.com)
  • The expression levels of VGLL3 mRNA and protein were analyzed in the freshly resected tumor and normal gastric tissues from GC patients by quantitative RT-PCR and Western blot, respectively. (researchgate.net)
  • Differential expression of miRNAs between normal and tumor tissues has been observed in various cancer types, suggesting a possible link between miRNA expression and the development of cancer [ 5 ]. (oncotarget.com)
  • In the context of cancer, appropriately activated DCs can induce anti-tumor immunity by activating innate immune cells and tumor-specific lymphocytes that target cancer cells. (mdpi.com)
  • 2. Department of Radiation Oncology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, and Key Laboratory of Tumor Radiosensitization and Normal Tissue Radioprotection of Liaoning Province, Shenyang, Liaoning 110042, China. (jcancer.org)
  • 10% of pancreatic cancers are associated with an underlying genetic component. (msdmanuals.com)
  • SAN FRANCISCO ― An experimental monoclonal antibody combined with chemotherapy could offer a new standard of care for patients with claudin-18.2+ (CLDN18.2+) / HER2− advanced gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma, say researchers in reporting a phase 3 trial. (medscape.com)
  • He said adults who don't exercise are at increased risk of developing certain cancers like breast, endometrial, or colon, but until recently the impact of less structured forms of vigorous physical activity was unable to be measured. (scitechdaily.com)
  • This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. (ucbraid.org)
  • This phase II trial studies how well abemaciclib works in treating patients with ovarian or endometrial cancer that has an activation of the CDK4/6 pathway and that has come back (recurrent). (ucbraid.org)
  • Giving abemaciclib may work better for the treatment of recurrent ovarian and endometrial cancer. (ucbraid.org)
  • High cytoplasmic OPN staining was observed in 100% of gastric carcinomas, 85% of colorectal carcinomas, 82% of transitional cell carcinomas of the renal pelvis, 81% of pancreatic carcinomas, 72% of renal cell carcinomas, 71% of lung and endometrial carcinomas, 70% of esophageal carcinomas, 58% of squamous cell carcinomas of the head and neck, and 59% of ovarian carcinomas. (aacrjournals.org)
  • While some of them showed reduced risks for colon, breast, and endometrial cancers, the relationship with other cancer types were inconclusive mainly because of the limited number of respondents who participated. (newhopemedicalcenter.com)
  • The findings were presented here at the Gastrointestinal Cancers Symposium (GICS) 2023, organized by the American Society of Clinical Oncology. (medscape.com)
  • Zimberelimab is considered an investigational medication, although in 2023 it was approved for use in China as a treatment for cervical cancer. (providence.org)
  • Cancer statistics, 2023. (msdmanuals.com)
  • CA Cancer J Clin 73(1):17-48, 2023. (msdmanuals.com)
  • All patients were treatment naive with CLDN18.2/HER2− locally advanced unresectable or metastatic mG/GEJ adenocarcinoma. (medscape.com)
  • Although the incidence of these cancers is lower in the United States than in other parts of the world, survival rates for people with locally advanced cancer that cancer that has spread outside the area where it started to other parts of the body (metastatic) or cannot be removed by surgery (unresectable) is approximately 5%, regardless of where they live. (providence.org)
  • In recent studies, adding programmed cell death protein 1 (PD-1) inhibitors to standard chemotherapy have resulted in a higher survival rate for people with locally advanced unresectable and/or metastatic cancer over chemotherapy alone. (providence.org)
  • The approval of this new first-line metastatic EGFR-mutated non-small cell lung cancer regimen, which inhibits the VEGFR and EGFR pathways together, is an important milestone in the treatment of this disease. (epicos.com)
  • Ramucirumab, in combination with erlotinib, is a welcomed first-line option to offer our patients with metastatic EGFR-mutated non-small cell lung cancer. (epicos.com)
  • This CYRAMZA combination regimen represents a new and meaningful treatment option for people with metastatic EGFR-mutated non-small cell lung cancer, and we are proud that it has been approved by the FDA for patients with this disease and the doctors who treat them," said Anne White, president of Lilly Oncology. (epicos.com)
  • Overall, Wang believes that these results validate claudin 18 as a new predictive biomarker for advanced gastric cancer, although he noted that widespread implementation for this indication may be limited, as the assay to determine claudin 18 levels is not widely available. (medscape.com)
  • For males, tobacco- and obesity-associated cancers were the leading groups among the five risk factor-associated cancers among all races and Hispanic people ( Figure 1 ). (cdc.gov)
  • 2 3 4 5 6 Because risk factor information is not routinely collected by cancer registries, estimates for risk factor-associated cancers often are based only on cancer type. (cdc.gov)
  • Using these standard definitions for risk factor-associated cancers can help facilitate comparisons of cancer burden across states and communities. (cdc.gov)
  • Lung cancer with epidermal growth factor receptor (EGFR)-activating mutations responds favorably to the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. (aacrjournals.org)
  • Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR), including gefitinib and erlotinib, have become the standard first-line therapy for patients with advanced non-small cell lung cancers (NSCLCs) harboring activating EGFR mutations ( 4 , 5 ). (spandidos-publications.com)
  • Fruit and vegetables do not seem to protect from ovarian cancer (581 verified cases of epithelial cancer) (11) . (aprifel.com)
  • Ovarian cancer today and tomorrow: A global assessment by world region and Human Development Index using GLOBOCAN 2020. (who.int)
  • Longevity - Research shows that physical activity can help you live longer and prevent early deaths from heart diseases and certain cancers. (newhopemedicalcenter.com)
  • One of the hypotheses tested in the EPIC study is the potential protective effect of fruit and vegetable consumption against certain cancers. (aprifel.com)
  • Overall, these results indicate that the potential beneficial effect of fruit and vegetables against certain cancers deserve further investigation, and that studies on specific types of vegetables and fruits, as well as studies using biological markers of diet are warranted. (aprifel.com)
  • Most cases of paraneoplastic AN involve an adenocarcinoma,[5] most commonly one arising in the gastrointestinal tract (stomach or liver[3] ) and less commonly in the lungs, ovaries, uterus, breasts, kidneys, prostate or bladder. (medscape.com)
  • With this approval, CYRAMZA has now received six FDA approvals to treat certain types of lung, liver, stomach and colorectal cancers. (epicos.com)
  • Men and women who have cancer in their biliary tract: liver and/or gallbladder and/or bile ducts that has spread to other parts of the body and cannot be taken out. (thechc.com)
  • b Percentage based on all invasive cancers by sex (total invasive cancers for males or females). (cdc.gov)
  • Invasive cancer incidence and survival-United States, 2013. (cdc.gov)
  • Finally, the data from 3659 invasive incident breast cancer cases in EPIC support previous evidence that vegetable and fruit intake is not associated with risk for breast cancer (9) and that prostate cancer is not associated with total fruit and vegetables consumption (10) . (aprifel.com)
  • Transcriptomic profiling of T-cell populations in non-muscle invasive and muscle invasive bladder cancer. (lu.se)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • This case is reported due to the rarity of cutaneous metastasis at multiple sites from a highly aggressive adenocarcinoma in a young patient, to emphasize the importance of cutaneous metastasis as a poor prognostic sign in patients with a history of cancer. (lww.com)
  • found that pyroptosis-related genes can be used for prognostic prediction of skin cutaneous melanoma and lung adenocarcinoma, respectively. (nature.com)
  • Here, we showed that hepatocyte growth factor (HGF), a ligand of MET oncoprotein, induces gefitinib resistance of lung adenocarcinoma cells with EGFR -activating mutations by restoring the phosphatidylinositol 3-kinase/Akt signaling pathway via phosphorylation of MET, but not EGFR or ErbB3. (aacrjournals.org)
  • We're encouraged by CYRAMZA's latest approval, which represents one step towards our goal of making EGFR-mutated non-small cell lung cancer into a manageable chronic disease," said Ivy Elkins, cofounder of EGFR Resisters . (epicos.com)
  • Gastric cancer (GC, 330 cases) and adenocarcinoma of oesophagus (ACO, 65 cases) were not related with fruit and vegetable in EPIC , although a potential beneficial effect of vegetables and of onion and garlic for the intestinal type of GC, and of citrus fruit against cardia GC and ACO, for which inverse associations were observed, cannot be discarded (8) . (aprifel.com)
  • The ADAPTA Study: ADjuvant chemotherAPy After Curative Intent resecTion of Ampullary Cancer. (rare-cancer.org)
  • This trial is looking to see how effective two different doses of the new drug that is being studied (onvansertib) are in treating your cancer, when they are given along with chemotherapy. (thechc.com)
  • By cancer sites, the highest incidence rates among males were prostate, lung and bronchus, and colon and rectum. (cdc.gov)
  • Among females, the three leading sites-breast, lung and bronchus, and colon and rectum-accounted for half of cancers diagnosed among females in 2016 ( Table 1 ). (cdc.gov)
  • Myeloma and cancers of the head and neck, rectum, and bladder also showed reduced risks but the significance is not as strong. (newhopemedicalcenter.com)
  • This trial is looking to see how well the study drug (Dato-DXd) works on biliary tract cancers that have spread, as well as how safe the drug is. (thechc.com)
  • Zolbetuximab plus mFOLFOX6 is a new potential standard treatment for these patients," said lead study author Kohei Shitara, MD, Department of Gastrointestinal Oncology, National Cancer Center Hospital East Kashiwa City, Chiba, Japan. (medscape.com)
  • The principal investigator is Gina Vaccaro , M.D. , medical director of Gastrointestinal Cancer Research at Providence Cancer Institute. (providence.org)
  • Cancer in the body and tail may cause splenic vein obstruction, resulting in splenomegaly, gastric and esophageal varices, and gastrointestinal hemorrhage. (msdmanuals.com)
  • Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality. (frontiersin.org)
  • According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in 185 countries produced by the International Agency for Research on Cancer (IARC), GC ranks fifth and fourth, respectively, and seriously threatens the survival and health of people all over the world. (frontiersin.org)
  • According to the GLOBOCAN 2020 estimates of incidence and mortality for 36 cancers in 185 countries produced by the International Agency for Research on Cancer (IARC), an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths occurred worldwide in 2020, and GC ranked fifth (5.6%) and fourth (7.7%), respectively ( 2 ). (frontiersin.org)
  • Information about new cancer cases (incidence) comes from CDC's National Program of Cancer Registries (NPCR) and NCI's Surveillance, Epidemiology, and End Results (SEER) Program. (cdc.gov)
  • The research, based on data from wearable devices of over 22,000 non-exercisers monitored for seven years, found an 18-32% reduction in cancer incidence with a minimum of 3.5-4.5 minutes of daily VILPA. (scitechdaily.com)
  • Physical inactivity-associated cancers include breast cancer in post-menopausal women, endometrium (corpus uterus) cancer, and colon cancer. (cdc.gov)
  • The recommended fam-trastuzumab deruxtecan-nxki dose for gastric cancer is 6.4 mg/kg administered as an intravenous infusion once every 3 weeks (21-day cycle) until disease progression or unacceptable toxicity. (ecancer.org)
  • Recently, MCM4 is reported to have a complex interaction with multiple cancer progression, including gastric, ovarian and cervical cancer. (bvsalud.org)
  • Gastric cancer tissue arrays were generated from stomach samples with TNM stage, invasion depth and the demography of these patients (n = 185). (researchsquare.com)
  • Thirty-four gastric adenocarcinoma samples and 20 normal gastric tissue controls (patients with chronic gastritis on endoscopy) were included. (biomedcentral.com)
  • Current and future burden of breast cancer: Global statistics for 2020 and 2040. (who.int)
  • Cancer in sub-Saharan Africa in 2020: a review of current estimates of the national burden, data gaps, and future needs. (who.int)
  • The preventability of cancer in Europe: A quantitative assessment of avoidable cancer cases across 17 cancer sites and 38 countries in 2020. (who.int)
  • For example, strong evidence suggests that physical activity reduces the risk of breast cancer in postmenopausal women, endometrium cancer, and colon cancer. (cdc.gov)
  • Triple-negative breast cancer. (aiom.it)
  • The study confirmed the findings of previous studies that physical activity can be linked to a lower risk of colon, breast, and entometrial cancer. (newhopemedicalcenter.com)
  • Men and women with Breast Cancer that has spread to other parts of the body. (thechc.com)
  • c Excludes basal and squamous cell carcinomas of the skin except when these occur on the skin of the genital organs and in situ cancers except urinary bladder. (cdc.gov)
  • OPN score and stage were also significantly correlated for specific cancer sites including bladder ( P = 0.01), colon ( P = 0.004), kidney ( P = 0.0001), larynx ( P = 0.035), mouth ( P = 0.046), and salivary gland ( P = 0.011). (aacrjournals.org)
  • Cervical squamous cell cancer. (aiom.it)
  • Unfortunately, patients are already in the terminal stage at this time, and the cancer cells have already invaded the surrounding organs or metastasized far away, which leads to the loss of the curative chance for most patients ( 1 ). (frontiersin.org)
  • This is one of the longest median overall survival outcomes for patients with locally advanced mG/GEJ adenocarcinoma in phase 3 trials, Shitera emphasized. (medscape.com)
  • The appearance of paraneoplastic AN usually coincides with the presence of malignancy, but it can precede or follow the diagnosis of cancer and thus may signal a relapse in patients with a history of cancer. (medscape.com)
  • The matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectroscopy-based genotyping system was used to genotype 601 individuals (200 lung cancer patients and 401 age- and sex-matched healthy controls) for polymorphisms in excision repair cross-complementing group 1 ( ERCC1 ) and ERCC5 genes. (jcancer.org)
  • Each new treatment option gives hope to those living with this disease and provides oncologists with more options that may help slow the spread of this deadly cancer, which is an important goal for many patients. (epicos.com)
  • Genetic testing is now offered routinely to all patients diagnosed with pancreatic cancer. (msdmanuals.com)
  • Adenocarcinomas of the head of the pancreas cause obstructive jaundice (which can cause pruritus) in 80 to 90% of patients. (msdmanuals.com)
  • Pancreatic cancer causes diabetes in up to half of patients, leading to symptoms of glucose intolerance (eg, polyuria and polydipsia). (msdmanuals.com)
  • Source: High-quality data from cancer registries funded by NPCR and SEER, covering 100% of the US population. (cdc.gov)
  • Quality of data from cancer registries in the Eastern Mediterranean region. (who.int)
  • In our study, we examined PKP1, PKP2, and PKP3 expression and their clinicopathological correlation with gastric cancer. (biomedcentral.com)
  • Fine-needle aspiration cytology of the nodule revealed it to be metastasis from gastric adenocarcinoma. (lww.com)
  • As an emerging cancer immunotherapy, oncolytic virotherapies (OVTs) can not only selectively lyse cancer cells, but also induce a systemic antitumor immune response. (frontiersin.org)
  • In a discussion of the paper, David H. Wang, MD, PhD, an associate professor in the Department of Internal Medicine at University of Texas Southwestern Medical Center, Dallas, pointed out that "zolbetuximab is the first molecularly targeted therapy, exclusive of immune checkpoint inhibitors, to demonstrate a statistically significant survival benefit in first-line treatment of advance gastric cancer since trastuzumab. (medscape.com)
  • Domvanalimab works by binding to TIGIT, which may activate the immune system to attack and destroy cancer cells. (providence.org)
  • The immune relevance of GNG7 and related genes was explored using renal cancer data from CCLE and TISIDB database. (biomedcentral.com)
  • ARCUS STAR-221 is designed to offer a more hopeful treatment option with higher survival rates for people with these cancers. (providence.org)
  • Five ways to improve international comparisons of cancer survival: lessons learned from ICBP SURVMARK-2. (who.int)
  • International variation in oesophageal and gastric cancer survival 2012-2014: differences by histological subtype and stage at diagnosis (an ICBP SURVMARK-2 population-based study). (who.int)
  • Trends in long-term cancer survival in Cali Colombia: 1998-2017. (who.int)
  • Pancreatic cancer survival by stage and age in seven high-income countries (ICBP SURVMARK-2): a population-based study. (who.int)
  • For example, the X-ray repair cross-complementing protein 1 gene ( XRCC1 ) codon 399 Gln allele and TP53 codon 72 Arg allele appear to have a protective effect against lung adenocarcinoma, especially in individuals older than 50 years of age [ 9 ]. (jcancer.org)
  • EPIC has confirmed previous findings of a potential protective effect of fruit intake against lung cancer in an analysis of 860 incident cases, while no association with vegetables was observed (6) . (aprifel.com)
  • In this study, we aimed to investigate the antitumor effects of antiangiogenic agent Ad-Endo combined with the oncolytic Ad dl 1520 on gastric cancer (GC) in vitro and in vivo and determine the mechanisms of these effects. (biomedcentral.com)
  • Lan X, Li Y, Wu Y, Li X, Xu L. The Association of ERCC1 and ERCC5 Polymorphisms with Lung Cancer Risk in Han Chinese. (jcancer.org)
  • Polymorphisms in DNA damage repair genes are important determinants for cancer susceptibility, clinical phenotype diversity, and therapy. (jcancer.org)
  • This study aimed to investigate the role of DNA damage repair gene polymorphisms in the risk of lung cancer. (jcancer.org)
  • ERCC5 rs4771436 and rs1047768 genotypes were associated with an increased risk of lung cancer, suggesting that polymorphisms in DNA repair genes are significantly related to the risk of lung cancer, and play an important role in the occurrence of lung cancer. (jcancer.org)
  • EPIC represents the largest single resource available for prospective investigations in the aetiology of cancers that can integrate questionnaires on lifestyle and diet, biomarkers of diet, metabolism and genetic polymorphisms, with the additional advantage of the contrast in cancer rates and dietary habits between centres (2) . (aprifel.com)
  • Background Gastric cancer (GC) is a malignancy with high morbidity/mortality, partly due to a lack of reliable biomarkers for early diagnosis. (researchsquare.com)
  • Gastric cancer (GC) is an important disease with high morbidity and mortality. (researchsquare.com)
  • With over two million new diagnoses each year, and nearly two million deaths worldwide, lung cancer is one of the most common malignancies in adults, according to the World Health Organization. (providence.org)
  • Because cancer registries do not routinely collect information about risk factors, cancer types associated with alcohol use, human papillomavirus infection (HPV), obesity, physical inactivity, and tobacco use were analyzed ( Figure 1 ). (cdc.gov)