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  • recurrent
  • Individuals with gastric outlet obstruction will often have recurrent vomiting of food that has accumulated in the stomach, but which cannot pass into the small intestine due to the obstruction. (wikipedia.org)
  • Tumours
  • Siewert-Stein classification is anatomical classification of the location of oesophago-gastric junction (OGJ) tumours Type I Adenocarcinoma of distal part of the oesophagus (centre located within between 1-5cm above the anatomic OGJ) Type II Adenocarcinoma of the real cardia (within 1cm above and 2cm below the OGJ) Type III Adenocarcinoma of the subcardial stomach (2-5cm below OGJ) Siewert JR, Stein HJ. (wikipedia.org)
  • Malignant Tumours of the stomach, including adenocarcinoma (and its linitis plastica variant), lymphoma, and gastrointestinal stromal tumours In a peptic ulcer it is believed to be a result of edema and scarring of the ulcer, followed by healing and fibrosis, which leads to obstruction of the gastroduodenal junction (usually an ulcer in the first part of the duodenum). (wikipedia.org)
  • Therapy
  • Surgery is indicated in cases of gastric outlet obstruction in which there is significant obstruction and in cases where medical therapy has failed. (wikipedia.org)
  • stomach
  • Gastric outlet obstruction (GOO) is a medical condition where there is an obstruction at the level of the pylorus, which is the outlet of the stomach. (wikipedia.org)
  • individuals
  • Laboratory Individuals with gastric outlet obstruction are often hypochloremic, hypokalemic, and alkalotic due to loss of hydrogen chloride and potassium. (wikipedia.org)
  • cells
  • Recently, bile acids were shown to be able to induce intestinal differentiation, in gastroesophageal junction cells, through inhibition of the epidermal growth factor receptor (EGFR) and the protein kinase enzyme Akt. (wikipedia.org)