CarcinomaAdvanced gastric cancerUlcerativeCarcinomasHuman gastricPapillaryMalignantTumorMucosaIntestinalPrognosticLesionsMetastaticStromalChronicStomach cancerCommonAppearanceVarietyStudiesTreatmentWorkEarly gastric cancerPrognosisMalignanciesPoorlyCancersTumorsAbstractClinicopathologicalAnalysesInvasiveCancer cellsSurvivalMolecularPatientsDiseaseCellsTherapy
Carcinoma13
- Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
- Gastric carcinoma is most commonly located in the region of gastric canal (prepyloric region), less common localization are the body, cardia and fundus. (poznayka.org)
- 1. Early gastric carcinoma, when carcinoma confined only mucosal layers. (poznayka.org)
- 2. Advanced gastric carcinoma, when it penetrates the muscular layer or beyond. (poznayka.org)
- 1. Pyloric (50%) gastric carcinoma. (poznayka.org)
- 2. Signet-ring cell carcinoma, scirrhous carcinoma, solid carcinoma (poorly-differentiated). (poznayka.org)
- Early gastric carcinoma is the term used to describe cancer limited to the mucosa and submucosa. (poznayka.org)
- Macroscopically, the lesions of early gastric carcinoma may have 3 patterns-superficial, polypoid and ulcer-associated. (poznayka.org)
- Microscopically, early gastric carcinoma is a typical glandular adenocarcinoma, usually well-differentiated. (poznayka.org)
- When the carcinoma crosses the basement membrane into the muscular propria or beyond, it is referred to as advanced gastric carcinoma. (poznayka.org)
- 3. Scirrhous carcinoma. (poznayka.org)
- Microscopically, it may be an adenocarcinoma or signet-ring cell carcinoma, extensively infiltrating the stomach wall, but due to marked desmoplasia cancer cells may be difficult to find. (poznayka.org)
- Accordingly, mucoepidermoid carcinoma (MEC) is the most frequent subtype, with more than 30% of the SGC cases, followed by the adenoid cystic carcinoma (ACC) with the pathology in 23.8% of all SGC cases, and the adenocarcinoma not otherwise specified [ 4 ]. (genominfo.org)
Advanced gastric cancer1
- Due to the unobvious early symptoms and the influence of some adverse factors such as tumor heterogeneity and low immunogenicity, patients with advanced gastric cancer (AGC) cannot benefit significantly from treatments such as radical surgical resection, radiotherapy, chemotherapy, and targeted therapy. (frontiersin.org)
Ulcerative1
- Macroscopically, ulcerative carcinomas are poorly-differentiated adenocarcinomas, which invade deeply into the stomach wall. (poznayka.org)
Carcinomas2
- Microscopically, fungating or polypoid carcinomas are well-differentiated adenocarcinomas, commonly papillary type. (poznayka.org)
- The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. (hivinhibitor.com)
Human gastric1
- Jang TJ: Expression of proteins related to prostaglandin E2 biosynthesis is increased in human gastric cancer and during gastric carcinogenesis. (edu.pl)
Papillary2
- Adenocarcinoma of the stomach is subclassified according to histologic description as follows: tubular, papillary, mucinous, or signet-ring cells, and undifferentiated lesions. (medscape.com)
- 1. Adenocarcinoma: papillary, mucoid, trabecular (well-differentiated). (poznayka.org)
Malignant2
- Gastric cancer (GC) is a common malignant tumor originating from gastric mucosa epithelial cells, and its onset is relatively insidious. (frontiersin.org)
- The most common cause of malignant biliary obstruction is pancreatic adenocarcinoma . (medscape.com)
Tumor1
- However, increased expression of COX−2 in gastric cancer was confirmed, and in cell culture or animal models, influence of COX−2 on tumor proliferation was indicated. (edu.pl)
Mucosa1
- Pre-cancer changes in the gastric mucosa. (poznayka.org)
Intestinal2
- The Lauren system classifies gastric cancer pathology as either type I (intestinal) or type II (diffuse). (medscape.com)
- Van Rees BP, Sivula A, Thoren S, Yokozaki H, Jakobsson PJ, Offerhaus GJA, Ristimaki A: Expression of microsomal prostaglandin E synthase−1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines. (edu.pl)
Prognostic1
- Soluble PD-L1 as a diagnostic and prognostic biomarker in resectable gastric cancer patients. (harvard.edu)
Lesions1
- However, in precancerous lesions of gastric cancer, COX−2 expression is controversial and the usefulness of COX−2 inhibitor has not been demonstrated. (edu.pl)
Metastatic1
- Next, a CT-guided biopsy of the lesion was performed and histology revealed a metastatic lesion, most likely from a primary breast adenocarcinoma [Figure 3] . (oaepublish.com)
Stromal1
- Gastrointestinal stromal tumors formerly classified as either leiomyomas or leiomyosarcomas account for 2% of gastric neoplasms (see Gastric Stromal Tumors ). (medscape.com)
Chronic1
- 3. Chronic gastric ulcer. (poznayka.org)
Stomach cancer1
- 19. Kuniyasu H, Yasui W, Kitadai Y, Yokozaki H, Ito H, Tahara E. Frequent amplification from the c-met gene in scirrhous variety stomach cancer. (hivinhibitor.com)
Common1
- The second most common gastric malignancies are lymphomas. (medscape.com)
Appearance1
- For confirmation of cancer in a pre-existing gastric ulcer, the characteristic microscopic appearance of peptic ulcer should be demonstrable with one portion of the base or the margin of the ulcer showing carcinomatous changes. (poznayka.org)
Variety1
- 21. Samuelson E, Levan K, Adamovic T, Levan G, Horvath G. Recurrent gene amplifications in human variety I endometrial adenocarcinoma detected by fluorescence in situ hybridization. (hivinhibitor.com)
Studies1
- Further studies about COX−2 and gastric cancer including clinical trials are needed, and also more studies should be performed about other PGE2 related enzymes as well as COX−2. (edu.pl)
Treatment1
- Signs and symptoms relating to orbital metastasis are usually noted late in the disease progression, and treatment generally consists of local radiotherapy to the orbit [ 6 ] in addition to treatment of the primary cancer, which in this case of ductal adenocarcinoma of the breast required hormonal therapy only. (oaepublish.com)
Work1
- The diagnosis of this condition has been made possible by extensive work on histogenesis of gastric cancer by Japanese pathologists by the use of fiberoptic endoscope and gastrocamera. (poznayka.org)
Early gastric cancer4
- 3. MUC4 and MUC1 expression in adenocarcinoma of the stomach correlates with vessel invasion and lymph node metastasis: an immunohistochemical study of early gastric cancer. (nih.gov)
- 10. Early gastric cancer of signet ring cell carcinoma is more amenable to endoscopic treatment than is early gastric cancer of poorly differentiated tubular adenocarcinoma in select tumor conditions. (nih.gov)
- Early gastric cancer in the gastric body. (medscape.com)
- however, some patients with incidental complaints are diagnosed with early gastric cancer. (medscape.com)
Prognosis4
- 6. Correlation of the immunohistochemical reactivity of mucin peptide cores MUC1 and MUC2 with the histopathological subtype and prognosis of gastric carcinomas. (nih.gov)
- Peritoneal carcinomatosis (PC) is the most frequent metastatic pattern of gastric cancer and its prognosis is extremely poor. (spandidos-publications.com)
- Peritoneal carcinomatosis (PC) is a characteristic feature of gastric cancer and is a critical factor underlying its poor prognosis ( 2 - 4 ). (spandidos-publications.com)
- The prognosis of gastric cancer is poor with an estimated relative 5-year survival rate of less than 20%[ 2 ]. (wjgnet.com)
Malignancies2
- Adenocarcinoma of the stomach constitutes 90-95% of all gastric malignancies. (medscape.com)
- The second most common gastric malignancies are lymphomas. (medscape.com)
Poorly2
- 1. A novel anti-MUC1 antibody against the MUC1 cytoplasmic tail domain: use in sensitive identification of poorly differentiated cells in adenocarcinoma of the stomach. (nih.gov)
- reported that microsatellite unpredictable (MSI) GCs had been significantly related to older age, woman gender, and predominant papillary solid-type and adenocarcinoma, differentiated adenocarcinoma poorly, plus they suggested that GC with MSI might result from differentiated-type carcinomas [5]. (eprf.ca)
Cancers1
- Effects of naso-gastric tube feeding on the dietary standing of children with most cancers. (gov.ph)
Tumors2
- Gastrointestinal stromal tumors formerly classified as either leiomyomas or leiomyosarcomas account for 2% of gastric neoplasms (see Gastric Stromal Tumors ). (medscape.com)
- Gastric cancer is one of the most common tumors worldwide. (wjgnet.com)
Abstract1
- Abstract Background Mechanistic target of rapamycin (mTOR) pathway is vital for the growth of gastric cancer (GC), but mTOR inhibitor everolimus had not been effective for the treating GCs. (eprf.ca)
Clinicopathological1
- Clinicopathological features and genomic profiles of hepatoid adenocarcinoma of the lung: Report of four cases. (cdc.gov)
Analyses1
- Univariate and multivariate success analyses of total gastric carcinomas (610 instances). (eprf.ca)
Invasive1
- 16. Combined evaluation of mucin antigen and E-cadherin expression may help select patients with gastric cancer suitable for minimally invasive therapy. (nih.gov)
Cancer cells1
- These cells can undergo epithelial-mesenchymal transition (EMT) to differentiate into an extracellular matrix-producing myofibroblastic phenotype in the presence of TGF-β released from gastric cancer cells ( 16 ). (spandidos-publications.com)
Survival1
- Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes. (cdc.gov)
Molecular1
- Improved molecular biological techniques and a better understanding of gastric carcinogenesis have allowed us to validate a variety of genes as molecular targets for gene therapy. (wjgnet.com)
Patients1
- Therefore, our study indicates that PSK has potential utility as an anti-fibrotic agent in the treatment of gastric cancer patients with PC. (spandidos-publications.com)
Disease1
- Most symptoms of gastric cancer reflect advanced disease. (medscape.com)
Cells1
- Adenocarcinoma of the stomach is subclassified according to histologic description as follows: tubular, papillary, mucinous, or signet-ring cells, and undifferentiated lesions. (medscape.com)
Therapy2
- Gene therapy for gastric cancer: Is it promising? (wjgnet.com)
- Sutter AP, Fechner H. Gene therapy for gastric cancer: Is it promising? (wjgnet.com)