• In this study, the qualitative identification of 34 designer drugs, mainly synthetic cannabinoids and synthetic cathinones, was performed by gas chromatography-triple quadrupole-tandem mass spectrometry with two different ionization techniques, including electron ionization (EI) and chemical ionization (CI), focusing only on qualitative seized-drug analysis, not from the toxicological point of view. (ojp.gov)
  • Therefore, in the present study, we performed untargeted lipid profiling of abalone tissues at different developmental stages as well as the hemolymph of mature female and male abalones using ultrahigh-performance liquid chromatography-tandem mass spectrometry. (hindawi.com)
  • Recently, we introduced a heated nebulizer microchip and showed its potential to interface liquid microseparation techniques and GC with API-MS. This study demonstrates the feasibility of GC-microchip atmospheric pressure photoionization-tandem mass spectrometry (GC-μAPPI-MS/MS) in the analysis of underivatized anabolic steroids in urine. (aalto.fi)
  • ISO 27108:2010 specifies a method for the determination of the dissolved amount of selected plant treatment agents and biocide products in drinking water, ground water and surface water by solid‑phase microextraction (SPME) followed by gas chromatography-mass spectrometry (GC‑MS). The limit of determination depends on the matrix, on the specific compound to be analysed and on the sensitivity of the mass spectrometer. (iso.org)
  • Discrimination rancidity degree of infant formula rice flour based on Headspace Solid-Phase Microextraction combined with Gas Chromatography-Mass Spectrometry as an alternative to sensory evaluation. (bvsalud.org)
  • To mitigating the serious threat of harmful volatile substances to the health of infants , an alternative method of odor evaluation were proposed based on Headspace solid-phase microextraction (HS-SPME) combined with Gas Chromatography-Mass Spectrometry (GC-MS) to discriminate the degree of rancidity of infant formula rice flour (IFRF). (bvsalud.org)
  • Like liquid chromatography-mass spectrometry, it allows analysis and detection even of tiny amounts of a substance. (wikipedia.org)
  • Gas chromatography/mass spectrometry (GC/MS) is a well-known instrumental technique used for the analysis of fire debris for accelerant detection. (astm.org)
  • Conifer seed oils from European Larch (Larix decidua), Norway Spruce (Picea abies) and European Silver Fir (Abies alba) have been analyzed by non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) with atmospheric pressure chemical ionisation (APCI)-MS detection. (unboundmedicine.com)
  • Detection of cobalamin deficiency using the urinary methylmalonic acid test by gas chromatography mass spectrometry. (bmj.com)
  • Detection was performed simultaneously by isotope ratio mass spectrometry and a single quadrupole mass spectrometer for analyte identity confirmation and assessment of peak purity. (uni-koeln.de)
  • To improve the accuracy of chemical molecule structure analysis, Gas Chromatography-Mass Spectrometry (GC-MS) combines the functions of Gas Chromatography (GC) and Mass Spectrometry (MS). Drug detection, fire investigati on, environmental analysis, investigating explosives, and identifying unidentified materials are some applications of GC-MS. Utilizing its extensive network of laboratories, Infinita Lab, USA, provides this test to its clients in the USA and other locations. (infinitalab.com)
  • Detection and quantification of amyloid β protein and variants by immunoprecipitation-mass spectrometry. (eanso.org)
  • Mass Spectrometry works by ionizing chemical compounds to generate charged ions, with a range of molecular masses. (infinitalab.com)
  • In 1964, Electronic Associates, Inc. (EAI), a leading U.S. supplier of analog computers, began development of a computer controlled quadrupole mass spectrometer under the direction of Robert E. Finnigan. (wikipedia.org)
  • By 1966 Finnigan and collaborator Mike Uthe's EAI division had sold over 500 quadrupole residual gas-analyzer instruments. (wikipedia.org)
  • The most common type of mass spectrometer (MS) associated with a gas chromatograph (GC) is the quadrupole mass spectrometer, sometimes referred to by the Hewlett-Packard (now Agilent) trade name "Mass Selective Detector" (MSD). (iitk.ac.in)
  • Individual compounds have their own unique mass spectrum since every pure compound always produces the same family of ions. (infinitalab.com)
  • Gas chromatography coupled with mass spectrometry (GC-MS) was used to analyze for phytochemicals and bioactive compounds in three species of Apocynacae, Gongronema latifolium , Vincetoxicum rossicum and Marsdenia edulis commonly found in tropical rainforest vegetation and used as food and traditional medicine by locals. (phcogj.com)
  • Gas chromatography-mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a test sample. (wikipedia.org)
  • We propose the addition of a labelled internal standards to nullify the effect of variable humidity on the analytical performance of needle trap micro-extraction combined with gas chromatography mass spectrometry. (unipi.it)
  • The first on-line coupling of gas chromatography to a mass spectrometer was reported in the late 1950s. (wikipedia.org)
  • The GC-MS is composed of two major building blocks: the gas chromatograph and the mass spectrometer. (wikipedia.org)
  • The molecules are retained by the column and then elute (come off) from the column at different times (called the retention time), and this allows the mass spectrometer downstream to capture, ionize, accelerate, deflect, and detect the ionized molecules separately. (wikipedia.org)
  • The mass spectrometer does this by breaking each molecule into ionized fragments and detecting these fragments using their mass-to-charge ratio. (wikipedia.org)
  • Sometimes two different molecules can also have a similar pattern of ionized fragments in a mass spectrometer (mass spectrum). (wikipedia.org)
  • Combining the two processes reduces the possibility of error, as it is extremely unlikely that two different molecules will behave in the same way in both a gas chromatograph and a mass spectrometer. (wikipedia.org)
  • The molecules take different amounts of time (called the retention time) to come out of (elute from) the gas chromatograph, and this allows the mass spectrometer downstream to capture, ionize, accelerate, deflect, and detect the ionized molecules separately. (iitk.ac.in)
  • Another relatively common detector is the ion trap mass spectrometer. (iitk.ac.in)
  • The sample analysis at the Mars instrument suite takes up more than half of the science payload onboard the Mars Science Laboratory Rover and to facilitate its mission, the Franklin rover will be carrying 26kg of scientific equipment, including four gas chromatography-mass spectrometry columns and a Raman spectrometer. (apexgasgenerators.com)
  • A suite of three instruments, including a Mass Spectrometer, Gas Chromatograph, and Tunable laser spectrometer this rover also scans and measures for the profusions of other light elements which are correlated with life, such as hydrogen, oxygen, and nitrogen. (apexgasgenerators.com)
  • Using GC and Mass Spec, MOMA blends a tiny gas chromatograph and mass spectrometer with an oven and laser. (apexgasgenerators.com)
  • For Solid Phase Micro Extraction (SPME), it is an equilibrium sampling method and can be used for gases, solids (Headspace) and liquids (direct). (utm.my)
  • Therefore, when an identifying mass spectrum appears at a characteristic retention time in a GC-MS analysis, it typically increases certainty that the analyte of interest is in the sample. (wikipedia.org)
  • The GC-MS analysis of flower extracts was performed using a GC and MS JEOL GC mate system and Interpretation on mass spectrum GC-MS was conducted using the database of National Institute Standard and Technology (NIST). (scialert.net)
  • This study describes the use of the GERSTEL MPS robotic with automated liquid option for the analysis of pesticide residues in hemp oil samples by direct liquid injection gas The number of cannabis containing products, such as extracts, tinctures, edibles, waxes and oils, available in the United States have increased significantly due to changes in state law and the 2018 Farm Bill. (gerstelus.com)
  • This study describes the use of the GERSTEL MPS robotic with automated liquid option for the analysis of pesticide residues in hemp oil samples by direct liquid injection gas chromatography/mass spectrometry (GC/MS). This technique is sensitive, accurate and precise and allows the quantification of pesticides of interest well below the established limits of quantification for the State of California. (gerstelus.com)
  • Currently, the qualitative seized-drug analysis is mainly performed by gas chromatography-electron ionization-mass spectrometry (GC-EI-MS) in which most of these emerging designer drug derivatives are extensively fragmented, not presenting a molecular ion in their mass spectra. (ojp.gov)
  • Using an integrated platform of metabolic labeling, high-resolution mass spectrometry and computational analysis, we report here a comprehensive dataset of the in vivo half-life of 3,228 and the expression of 8,064 cardiac proteins, quantified under healthy and hypertrophic conditions across six mouse genetic strains commonly employed in biomedical research. (nature.com)
  • All analyses were conducted on a Gas Chromatography-Mass Spectrometry (GC-MS)-Olfactometry system where the human nose is used as a detector simultaneously with chemical analysis via MS. The effects of sampling time, distance from a source, and the presence of particulate matter (PM) on the abundance of specific gases, odor intensity, and odor character were tested. (iastate.edu)
  • Identification of stigmasterol by preparative thin-layer chromatography, infrared, gas chromatographyâ€"mass spectrometry analysis, and antioxidant properties of Cenchrus ciliaris L. (greenpharmacy.info)
  • Then, partial least squares discriminant analysis was performed on the basis of the serum fatty acids detected by gas chromatography/mass spectrometry. (elsevierpure.com)
  • The instrument enables mass spectrum measurement for qualitative analysis or identification of unknowns and Selected Ion Monitoring (SIM) and MRM Measurement for quantitation of trace elements. (utm.my)
  • Gas Chromatography-Mass Spectrometry Analysis of Photosensitive Characteristics in Citrus and Herb Essential Oils. (eanso.org)
  • Since cyanide forms volatile hydrogen cyanide gas, tissue sampling techniques, storage, and cyanide analysis must be done with caution. (cdc.gov)
  • Established isotope ratio mass spectrometry methods for analyzing urinary steroids for doping control purposes consist of up to two time-consuming HPLC purification steps to achieve the required purity of all analytes. (uni-koeln.de)
  • The gas chromatograph utilizes a capillary column whose properties regarding molecule separation depend on the column's dimensions (length, diameter, film thickness) as well as the phase properties (e.g. 5% phenyl polysiloxane). (wikipedia.org)
  • In a gas chromatograph, the sample chemical mixture is vaporized in an oven and transported by an inert carrier gas into a column (packed or capillary), containing the solid phase (termed stationary phase). (infinitalab.com)
  • Parent ions of selected mass-to-charge ( m/z ) values, characteristic for petrol, are stored within the ion trap. (astm.org)
  • TGs containing Delta5-UPIFAs have a higher retention in comparison with common TGs found in plant oils with single methylene interrupted Delta6(9)-FAs and also significantly changed relative abundances of fragment ions in APCI mass spectra. (unboundmedicine.com)
  • The ions are then accelerated in an electric field and separated in vacuum, depending on their mass as well as their charge. (infinitalab.com)
  • The separated ions are analyzed by spectrometry principles. (infinitalab.com)
  • The targeted method successfully differentiated 50 cannabinoids based on either retention time differences or mass spectral dissimilarity - determined using a newly developed spectral comparison test. (ojp.gov)
  • In addition, CI mass spectra and MRM mass spectra of these designer drug derivatives can be used as a potential supplemental database along with EI mass spectral database. (ojp.gov)
  • In contrast to steady-state protein abundance, which may be quantified directly in mass spectrometry (MS) by spectral intensity 16 , 17 or sampling frequency 18 , 19 , protein turnover rates cannot be predicted from steady-state data 20 , requiring instead methods that can distinguish old and new protein molecules in mass spectra 11 , 21 . (nature.com)
  • Mass spectrometers equipped with atmospheric pressure ion sources (API-MS) have been designed to be interfaced with liquid chromatographs (LC) and have rarely been connected to gas chromatographs (GC). (aalto.fi)
  • This method is applicable to the determination of the sum of SCCPs in unfiltered surface water, ground water, drinking water and waste water using gas chromatography-mass spectrometry with electron capture negative ionization (GC-ECNI-MS). (iso.org)
  • There are two main types of UDTs-- immunoassay drug testing conducted at a laboratory or at the point of care in a provider's office, and laboratory-based gas or liquid chromatography/mass spectrometry. (cdc.gov)
  • Serum metabolites were quantified by using gas chromatography-mass spectrometry and ultrahigh performance liquid chromatography-mass spectrometry. (nih.gov)
  • The implementation of CI source facilitates the determination of molecular mass and the identification of seized designer drugs. (ojp.gov)
  • ISO 12010:2012 specifies a method for the quantitative determination of the sum of short-chain polychlorinated n ‑alkanes, also known as short-chain polychlorinated paraffins (SCCPs), in the carbon bond range n -C 10 to n -C 13 inclusive, in mixtures with chlorine mass fractions ("contents") between 49 % and 67 %, including approximately 6 300 of approximately 8 000 congeners. (iso.org)
  • Development of a thermal desorption-gas chromatography-mass spectrometry method for determination of styrene in air. (edpsciences.org)
  • A thermal desorption-gas chromatography-mass spectrometry method for determination of styrene in industrial indoor and outdoor air is presented. (edpsciences.org)
  • Mass Spectrometers can work in both full scan and selective ion monitoring (SIM) modes. (infinitalab.com)
  • Multidimensional gas chromatography consists of two gas chromatographs connected by a pressure-controlled heart-cutting device. (uni-koeln.de)
  • We here describe the implementation of an entirely automated (closed-loop) strategy for doing this and apply it to the optimization of gas chromatographic separations of the metabolomes of human serum and of yeast fermentation broths. (nih.gov)
  • The serum levels of fatty acids, including free fatty acids and esterified fatty acids, were evaluated by gas chromatography/mass spectrometry. (elsevierpure.com)
  • This volume details the principles and instrumentation of gas chromatography-mass spectrometry (CG-MS), and outlines industrial, environmental, pharmaceutical, clinical, toxicological, forensic and food-related applications, revealing findings from the laboratories of 40 contributing scientists around the world using GC-MS in practice. (dattanibookagency.in)
  • This paper outlines a six-step, data-driven, framework to develop and evaluate gas chromatography mass spectrometry (GC-MS) methods for targeted classes of drugs. (ojp.gov)
  • This paper describes a method of analyzing arson accelerants using gas chromatography coupled with ion trap mass spectrometry/mass spectrometry (GC/MS/MS). Petrol was investigated as an accelerant. (astm.org)
  • The objective of the present study was to evaluate the effect of biofield energy treatment on the isotopic abundance ratios of PM+1/PM , and PM+2/PM in o- and m-nitrophenol using the gas chromatography-mass spectrometry. (omeka.net)
  • The abundance of specific gases and odor was amplified when plates collected PM. The results of this research indicate that PM is major carrier of odor and several key swine odorants. (iastate.edu)
  • We are a laboratory equipment manufacturer, specialising in bespoke gas generator systems for academic, industrial and laboratory applications. (apexgasgenerators.com)
  • Gas Chromatography Mass Spectrometry_Laboratory Testing Capabilities_Quality Assurance_Technical Services_Jiaxing Focusimple Electronics Co., Ltd. (focusimple.com)
  • The molecules carried in the gas (termed mobile phase), are eluted at different times from the column depending on the affinity of molecules for the stationary phase. (infinitalab.com)
  • If you are interested in finding out more in regards to Gas Chromatography and what Apex's Nitrogen Generators can do in regards to your Gas Chromatography application requirements, check out our range of mini Nevis Nitrogen Generators by following the link below. (apexgasgenerators.com)
  • Gas chromatography-mass spectrometry (GC-MS) was used to identify the presence of IBOA in OmniPod. (lu.se)