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  • immune
  • Furthermore, endogenous endorphins, as modulators, are involved in the crosstalk between the nervous and immune systems directly or indirectly through the hypothalamic-pituitary-adrenal axis. (usda.gov)
  • pain
  • As components of an intrinsic pain suppression system, endorphins are involved in regulating the pathogenesis of pain. (usda.gov)
  • Activation of the endorphin system triggers an endogenous analgesia cascade by modulating nociceptive signals within the local circuits, such as in the dorsal horn of the spinal cord (the gate control theory of pain), resulting in reducing or inhibiting nociceptive messages forwarded to the somatosensory system. (usda.gov)
  • particular
  • There once was the thought that an amphipathic helix was required for a particular endorphin to be active, but I haven't heard anything about it for years. (biology-online.org)
  • order
  • These were names given to distinguish the types of endorphins and may reflect nothing more than elution order out of a column or tissue source. (biology-online.org)