Gamma 12 subunits protein subunits. Medical search. Frequent questions

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. (origene.com)
The large number of RP genes identified can be grouped into a number of functional classes: (1) proteins of the visual cascade, (2) proteins of the visual cycle, (3) photoreceptor cell transcription factors, (4) proteins related to catabolic processes, and (5) genes of unknown function. (bmj.com)
Chicken gamma genes displayed similar structures and high sequence homology compared to corresponding mammalian gamma gene homologues. (usda.gov)
Proteins produced from other genes involved in GEFS+ are subunits of another type of ion channel called the GABA A receptor. (medlineplus.gov)
A large molecule of DNA that is coiled around specific proteins, called histones, and that contains many genes. (beyondachondroplasia.org)
As opposed to other styles of muscles dystrophy, where mutations take place in genes encoding structural protein, calpainopathy was the initial reported kind of dystrophy predetermined by mutations within a gene encoding a proteolytic enzyme. (exposed-skin-care.net)
Based on a better understanding of the basement membrane zone (BMZ) and the genes responsible for its components, newer treatments (eg, gene or protein therapy) may provide solutions to the skin fragility found in patients with epidermolysis bullosa. (medscape.com)

Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. (wikipedia.org)
Heterotrimeric G proteins: organizers of transmembrane signals. (genome.jp)
Receptors transduce these signals to alter intracellular metabolism and cellular responsiveness through heterotrimeric G protein/second messenger pathways or through small GTP-binding protein/protein kinase cascades. (duke.edu)
The Ca(2+) channel inhibition and K(+) channel activation are mediated by beta gamma subunit release from a heterotrimeric G-protein. (epfl.ch)
In heterotrimeric G-protein signalling, cell surface receptors (GPCRs) are coupled to membrane-associated heterotrimers comprising a GTP-hydrolysing subunit G-alpha and a G-beta/G-gamma dimer. (embl-heidelberg.de)
Interaction of heterotrimeric G protein Galphao with Purkinje cell protein-2. (embl-heidelberg.de)
The heterotrimeric G protein Galphao is ubiquitously expressed throughout the central nervous system, but many of its functions remain to be defined. (embl-heidelberg.de)

Western blotting was used to detect the expressions of cyclinD1, CDK2, Bcl2, β-catenin and phosphorylation of the key proteins in the MAPK signaling pathway. (bvsalud.org)

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). (ageing-map.org)
This subunit is one of the gamma regulatory subunits of AMPK. (ageing-map.org)
Homo sapiens inhibitor of nuclear factor kappa B kinase regulatory subunit gamma (IKBKG), transcript variant 3, mRNA. (origene.com)
The AMPK enzyme complex consists of one catalytic (alpha) and two regulatory (beta and gamma) subunits. (usda.gov)
Mattera R, Codina J, Crozat A, Kidd V, Woo SL, Birnbaumer L: Identification by molecular cloning of two forms of the alpha-subunit of the human liver stimulatory (GS) regulatory component of adenylyl cyclase. (smpdb.ca)
A GTPase activator for the nuclear ras-related regulatory protein RAP-1A. (embl-heidelberg.de)

This gene encodes the gamma chain isoform laminin, gamma 3. (wikipedia.org)
Human p19 cDNA encodes a 189 amino acid residue (aa) precursor protein with a putative 19 aa signal peptide and 170 aa mature protein. (rndsystems.com)

Magnesium is involved in nearly every aspect of biochemical metabolism (eg, DNA and protein synthesis, glycolysis, oxidative phosphorylation). (medscape.com)

AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. (ageing-map.org)
AMP-activated protein kinase (AMPK) is involved in the regulation of cellular energy homeostasis and, on the whole animal level, in regulating energy balance and food intake. (usda.gov)
The objective of this study was to characterize chicken AMPK gamma gene expression. (usda.gov)
A molecular cloning strategy involving primer-directed RT-PCR and 3'- and 5'-RACE was developed to sequence chicken cDNAs corresponding to complete coding regions and portions of the 5'- and 3'-untranslated regions of AMPK gamma-1, -2 and -3 mRNA transcripts. (usda.gov)

Full length human recombinant protein of human IKBKG (NP_003630) produced in HEK293T cell. (origene.com)
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. (rndsystems.com)
Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (rndsystems.com)
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
As an alternative, please consider our next generation Recombinant Human IL-4 Protein, ( BT-004-GMP ). (rndsystems.com)
This has equivalent bioactivity to Recombinant Human IL-4 Proteins ( BT-004 ) and Catalog # BT-004-AFL.These combine R&D Systems quality with scalability that allows for a solid supply chain. (rndsystems.com)
All Recombinant Human IL-4 proteins are measured in a cell proliferation assay using TF-1 human erythroleukemic cell line. (rndsystems.com)
2 μg/lane of Animal-Free™ Recombinant Human IL‑4 Protein (Catalog # BT-004-AFL) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 13 kDa underreducing conditions. (rndsystems.com)
We have recently conducted a first-in-human clinical trial to evaluate the safety and immunogenicity of the recombinant, full-length merozoite surface protein 1 (MSP1 FL ) formulated with GLA-SE as adjuvant. (nature.com)

However, mutations in the beta subunit of the rod cGMP-phosphodiesterase gene, 8- 11 in the ATP binding cassette receptor gene, 12 in the TULP1 gene, 13 in the alpha subunit of the rod cGMP gated channel, 14 and in the USH2A gene 15 have been detected in a small percentage of Spanish ARRP families. (bmj.com)
Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. (genome.jp)

Harris BA: Complete cDNA sequence of a human stimulatory GTP-binding protein alpha subunit. (smpdb.ca)

Stable for 12 months from date of receipt. (origene.com)
12 months from date of receipt, -20 to -70 °C as supplied. (rndsystems.com)

Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. (wikipedia.org)
These included 17 peaks in the omega-gliadin fractions (F1-4), 12 in the high molecular weight (HMW) glutenin subunit fractions (F5-8), 59 in the alpha- and beta-gliadins and low molecular weight (LMW) glutenin subunit fractions (F9-31) and 5 peaks in the gamma-gliadin fractions (F32-35). (unboundmedicine.com)
At least 16 different alpha subunits (39-52 kDa), 5 beta subunits (36 kDa) and 12 gamma subunits (6-9 kDa) are known. (genome.jp)
G alpha subunit types in B10 cells were also identified. (epfl.ch)
The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit. (embl-heidelberg.de)
GTP/G-alpha complex dissociates from the trimer and associates to an effector until the intrinsic GTPase activity of G-alpha returns the protein to GDP bound form. (embl-heidelberg.de)
Reassociation of GDP bound G-alpha with G-beta/G-gamma dimer terminates the signal. (embl-heidelberg.de)
The vaccines were found to elicit antibodies with 5-8 times more protection against the alpha, beta, gamma, delta and omicron variants, as compared to the unmodified mRNA (Fig.1). (sinica.edu.tw)
This is the first glycosite-deleted SARS-CoV-2 mRNA vaccine developed which was shown to have a broad-spectrum of protection against SARS-CoV-2 and the five variants of concern, including the alpha, beta, gamma, delta and omicron variants, and this new strategy could be applied to the development of other mRNA vaccines. (sinica.edu.tw)
Image analysis of the matched maps identified 7 proteins that were either over- or down-expressed: activated protein kinase c receptor (LACK), alpha tubulin (×2), prostaglandin f2-alpha synthase, protein disulfide isomerase, vesicular transport protein and a hypothetical protein. (who.int)

Phycocyanobilin 1alpha84 of APC-PY forms 5 hydrogen bonds with 3 residues in subunit 2beta of another monomer. (rcsb.org)
Moreover, cns does not read the subunit key, so you may need to renumber the residues by changepdb, command rr. (lu.se)

The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. (rndsystems.com)
Calpain 3 provides 54 and 51% series homology towards the 80 kDa subunits of - and m-calpains, respectively, and stocks similar properties with one of these ubiquitously portrayed calpains such as for example Ca2+- reliant activation and maximal activity at natural pH (1). (exposed-skin-care.net)

The highly conserved Asp-Gln-Arg triad within the GoLoco motif participates directly in GDP binding by extending the arginine side chain into the nucleotide binding pocket, highly reminiscent of the catalytic arginine finger employed in GTPase-activating protein. (embl-heidelberg.de)

Characterization and channel coupling of the P2Y(12) nucleotide receptor of brain capillary endothelial cells. (epfl.ch)

Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. (rndsystems.com)
The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. (rndsystems.com)
IL-23 is a dimeric cytokine related to IL-12, Dr. Krueger says. (dermatologytimes.com)
Receptors for the Fc region of IgG (Fc gamma Rs) are members of the Ig superfamily that function in the activation or inhibition of immune responses such as degranulation, phagocytosis, ADCC (antibody-dependent cellular toxicity), cytokine release, and B cell proliferation (1‑3). (novusbio.com)
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting pbmc. (lu.se)

Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity. (duke.edu)
Here, we report that GIT1 overexpression regulates internalization of numerous, but not all, G protein-coupled receptors. (duke.edu)
GIT1 only affects the function of G protein-coupled receptors that are internalized through the clathrin-coated pit pathway in a beta-arrestin- and dynamin-sensitive manner. (duke.edu)
Furthermore, the GIT1 effect is not limited to G protein-coupled receptors because overexpression of this protein also affects internalization of the epidermal growth factor receptor. (duke.edu)
Thus, GIT1 is a protein involved in regulating the function of signaling receptors internalized through the clathrin pathway and can be used as a diagnostic tool for defining the endocytic pathway of a receptor. (duke.edu)
Broadly, my research focuses on the role for G protein-coupled receptors in the pathophysiology of asthma. (duke.edu)
G protein-coupled receptors figure largely in the pathology and treatment of this disease. (duke.edu)
2-MeSADP activated (EC(50), 0.1 nm) GIRK1/GIRK2 inward rectifier K(+) channels when co-expressed with P2Y(12) receptors in sympathetic neurons. (epfl.ch)
however, a full inactivation followed, absent with P2Y(12) receptors. (epfl.ch)
This molecule binds to high affinity IL-2 receptors and when internalized into cells, releases enzymatic fragments that inhibit protein synthesis and lead to apoptotic cell death. (dermatologytimes.com)
The CD64 proteins are high affinity receptors (~10 -8 ‑10 -9 M) capable of binding monomeric IgG, whereas the CD16 and CD32 proteins bind IgG with lower affinities (~10 -6 ‑10 -7 M) only recognizing IgG aggregates surrounding multivalent antigens (1, 4). (novusbio.com)

It's a naturally occuring peptide (small sequence of aminoacids, which comprise proteins) in the human body, which binds to the Natriuretic-Peptide Receptor B (NPR B) existing on the surface of chondrocytes, in the bone, which induces the synthesis of cyclic guanosine-3′,5′-monophosphate (cGMP) molecules, which, in turn, inhibit the MAPK pathway of FGFR3 (by inhibiting certain enzymes in this pathway). (beyondachondroplasia.org)

12): 1071-1080, 2023. (bvsalud.org)

The presence or absence of one exon by alternative splicing of the gamma-1 gene resulted in two transcript variants which code for predicted proteins containing 298 amino acids (4 cystathionine beta-synthase domains, CBSD) or 276 amino acids (3 CBSD). (usda.gov)
ATP synthase membrane subunit g [Sourc. (gsea-msigdb.org)

The follicle-stimulating hormone receptor (FSHR) is a transmembrane G protein-coupled receptor located in the ovary, testis, and uterus. (smpdb.ca)

HMW glutenin subunits including Ax2*, Dx5, Bx7, and Dy10 (consistent with the known profile of Teal), and LMW glutenin subunits including six from group 3 type II and 1 from group 2 type I, were identified with reasonable sequence coverage from HPLC fraction 5, 7, 17, and 18. (unboundmedicine.com)
Although existing protin-centric informatics resources provide the biomedical research community with well-curated compendia of protein sequence and structure, these resources lack formal ontological representations of the relationships among the proteins themselves. (biomedcentral.com)
We show that this receptor in B10 cells is identical in sequence to the P2Y(12) ADP receptor ('P2Y(T)') of platelets. (epfl.ch)

It differs from other enzyme subtypes in that it lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE. (curehunter.com)

Two classes of intracellular proteins act as inhibitors of G protein activation: GTPase activating proteins (GAPs), which enhance GTP hydrolysis and guanine dissociation inhibitors (GDIs), which inhibit GDP dissociation. (embl-heidelberg.de)

mRNA and protein expressions of Ngb and HIF-1α showed positive in different tissues of the yak and cattle telencephalon. (bvsalud.org)
In this study, Dr. Chung-Yi Wu, a postdoctoral fellow, designed and studied the mRNA vaccines of SARS-CoV-2 spike protein with deletion of the glycosites in the RBD or the subunit 2 (S2) domain. (sinica.edu.tw)
Of particular significance in this study is that deletion of the glycosites in S2 led to the expression of misfolded S protein which was found to induce 2-3 times more CD8+ T cell immune response as compared to the unmodified mRNA. (sinica.edu.tw)
In this study, the team found that using mRNA as vaccine, they were able to address this problem and study the impact of protein glycosylation on immune response in vivo through expression of the de-glycosylated protein inside the cell. (sinica.edu.tw)

This protein initially was identified as an interacting partner for the G protein-coupled receptor kinases, and its overexpression was found to affect signaling and internalization of the prototypical beta(2)-adrenergic receptor. (duke.edu)
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. (duke.edu)
Receptor and G betagamma isoform-specific interactions with G protein-coupled receptor kinases. (duke.edu)
The G protein-coupled receptor (GPCR) kinases (GRKs) phosphorylate and desensitize agonist-occupied GPCRs. (duke.edu)
The IKB is phosphorylated by a multiprotein complex with two kinases subunits. (medscape.com)

Furthermore, the deleterious aftereffect of missense mutations can occur not merely from immediate disruption of CAPN3 function(s), but additionally from disruption from the protein's structural integrity, that could affect its intra or intermolecular protein lead and interactions to decreased stability or altered localization. (exposed-skin-care.net)
NEMO consists of 10 exons, and most mutations cause deletions of exons 4-10, resulting in a truncated protein. (medscape.com)
Hypomorphic mutations may impair but not abolish NEMO protein function. (medscape.com)

ProComp, the focus of this manuscript, represents multi-protein complexes, with an initial (but not exclusive) emphasis on protein components of complexes in mouse and human. (biomedcentral.com)
Author Manuscript not ) subunit. (cdc.gov)

Logical and semantic access to related protein forms is critical for advancing bioinformatics approaches to representing, modeling, and reasoning about complex biological systems at the genomic and cellular level [ 1 ]. (biomedcentral.com)
Genomic analysis of G protein gamma subunits in human and mouse - the relationship between conserved gene structure and G protein betagamma dimer formation. (musc.edu)
In 2000, the International Incontinentia Pigmenti Consortium reported that incontinentia pigmenti is caused by a genomic rearrangement of the gene for NEMO, or nuclear factor kappa B essential modulator (IKBKG-IKK gamma). (medscape.com)

For the gamma-2 gene, use of an alternate initiation site and promoter and/or alternative splicing resulted in four different transcript variants which code for predicted proteins containing 567 (4 CBSD), 452 (4 CBSD), 328 (3 CBSD) and 158 (2 CBSD) amino acids. (usda.gov)
Alternative splicing of exon 3 in the gamma-3 gene resulted in a shift of the open reading frame and the production of 'long' and 'short' transcript variants that code for predicted proteins of 383 and 363 amino acids, both with 4 CBSD. (usda.gov)

Codina J, Stengel D, Woo SL, Birnbaumer L: Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical. (smpdb.ca)

and when administered together either as a complex or as a fusion protein of IL-15 with the extracellular 'sushi' domain of the IL-15R? (immune-source.com)

ProComp leverages, and cross references, entries in existing protein-centric informatics resources, including the protein complexes that are represented in the Cellular Component branch of the Gene Ontology. (biomedcentral.com)
cAMP then activates protein kinase A (PKA) which phosphorylates downstream effectors that lead to a specific cellular response. (smpdb.ca)

The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells. (wikipedia.org)

EC(50), 2 nm), ADP, and adenosine 5'-O-(2-thio)diphosphate were agonists of cAMP decrease, and 2-propylthio-D-beta,gamma-difluoromethylene-ATP was a competitive antagonist (K(B), 28 nm), as in platelets. (epfl.ch)

Small nucleic acid molecules (20 to 60 DNA or RNA nucleotides) which bind with high specificity to a specific protein or organic molecule [ 2 ]. (beyondachondroplasia.org)

We have performed a detailed characterization and identification of wheat gluten proteins obtained from the Teal variety of Canadian hard red spring wheat. (unboundmedicine.com)
These results suggest that the combination of RP-HPLC with MS and MS/MS techniques is a promising approach for the characterization of wheat gluten proteins. (unboundmedicine.com)
TY - JOUR T1 - Characterization of wheat gluten proteins by HPLC and MALDI TOF mass spectrometry. (unboundmedicine.com)

The Protein Ontology (PRO) Consortium is filling this informatics resource gap by developing ontological representations and relationships among proteins and their variants and modified forms. (biomedcentral.com)
The team of Professor Che Ma , Kuo-I Lin and Chi-Huey Wong previously showed that immunization with mono-GlcNAc decorated S protein (SMG) induced broadly protective antibody and CD4+ as well as CD8+ T cell responses against SARS-CoV-2 and the variants of concern. (sinica.edu.tw)

Representing species-specific proteins and protein complexes in ontologies that are both human- and machine-readable facilitates the retrieval, analysis, and interpretation of genome-scale data sets. (biomedcentral.com)
The explicit representation of protein complexes in PRO--defining each member of the complex at the level of its isoform, variant, or modified form--provides the ability to represent complex biological knowledge as it is emerging in the experimental research community in structures that are both human readable and accessible to algorithmic approaches. (biomedcentral.com)
Detects human Fc gamma RII/CD32 in direct ELISAs and Western blots. (novusbio.com)
The "self"-protein albumin in mouse airway fluid was uniquely modified by GSH-MDI at position 414K, a preferred site of MDI reactivity on human albumin. (cdc.gov)

The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. (wikipedia.org)

The safety and efficacy of Alzain in children below the age of 12 years and in adolescents (12-17 years of age) have not been established. (medicines.org.uk)

However, it was also found that the gamma 3 is a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. (wikipedia.org)
The SCN1A gene and others associated with GEFS+ provide instructions for making pieces (subunits) of channels that transport positively charged sodium atoms (sodium ions) into cells. (medlineplus.gov)
According to this hypothesis, cells exposed to GNG7 will stop further proliferation and start the differentiation process mediated by G protein signals. (biomedcentral.com)
from the Greek "eating of self" - It's a process of self-degradation used by cells for balancing sources of energy during development and nutrient stress, as well as in removing "broken" (misfolded or aggregated) proteins, organelles and pathogens. (beyondachondroplasia.org)

ProForm represents species-specific and species-independent classes of protein isoforms, co- and post-translationally modified forms, and variant forms. (biomedcentral.com)

The specificity of the GIT1 effect is not related to the type of G protein to which a receptor couples, but rather to the endocytic route it uses. (duke.edu)

The NEMO protein is required for the activation of the kinase complex. (medscape.com)

Because proteins are often functional only as members of stable protein complexes, the PRO Consortium, in collaboration with existing protein and pathway databases, has launched a new initiative to implement logical and consistent representation of protein complexes. (biomedcentral.com)
The presence in the brain capillary endothelial cell of the P2Y(12) receptor is a significant extension of its functional range. (epfl.ch)

Mammalian regulators of G-protein signalling 12 and 14 (RGS12 and RGS14), multifaceted signal transduction regulators. (embl-heidelberg.de)
Mammalian Purkinje-cell protein-2 (Pcp2). (embl-heidelberg.de)
Drosophila protein Rapsynoid (also known as Partner of Inscuteable, Pins) and its mammalian homologues AGS3 and LGN. (embl-heidelberg.de)

In this study, we undertook extensive genome-wide comparative analyses of twelve species that conform the Pectobacterium genus. (mdpi.com)
We describe here how the PRO Consortium is meeting the challenge of representing species-specific protein complexes, how protein complex representation in PRO supports annotation of protein complexes and comparative biology, and how PRO is being integrated into existing community bioinformatics resources. (biomedcentral.com)
PRO is a unique database resource for species-specific protein complexes. (biomedcentral.com)
PRO facilitates robust annotation of variations in composition and function contexts for protein complexes within and between species. (biomedcentral.com)

Several mechanisms regulate the signal output at different stage of the G-protein cascade. (embl-heidelberg.de)

Disulfide-bonded heterodimer of 40 kda and 35 kda subunits. (lu.se)

Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. (biomedcentral.com)
Protein complexes are distinguished from protein-protein interactions in that they are continuant entities, i.e. they endure or continue to exist through time. (biomedcentral.com)
In the GO, types of protein complexes are defined in terms of constituent macromolecule classes and the function(s) that the complexes carry out. (biomedcentral.com)
A major contribution of PRO as a protein biology community informatics resource is that it provides a formal ontological structure with foundation in Basic Formal Ontology http://www.ifomis.org/bfo/ to describe types of protein complexes and gives these types unique, permanent identifiers http://www.obofoundry.org/id-policy.shtml . (biomedcentral.com)

Fc gamma Rs that deliver an activating signal either have an intrinsic immunoreceptor tyrosine-based activation motif (ITAM) within their cytoplasmic domains or associate with one of the ITAM-bearing adapter subunits, FcR gamma or zeta (3, 5). (novusbio.com)

We profiled antibody binding responses to coronavirus antigens, including spike (S) and nucleocapsid (N) proteins of SARS-CoV-2, SARS-CoV-1, MERS-CoV, and 4 endemic coronaviruses. (cdc.gov)

The chromophore-protein interactions and possible pathway of energy transfer were discussed. (rcsb.org)

O. Caldararu, F. Manzoni, E. Oksanen, D. T. Logan & U. Ryde (2019) "Refinement of protein structures using a combination of quantum mechanical calculations with neutron and X-ray crystallographic data" Acta Cryst. (lu.se)

Emerging evidence suggested that zinc finger protein 831 (ZNF831) was associated with immune activity and stem cell regulation in breast cancer. (bvsalud.org)
In the mating pheromone response pathway, G-protein-mediated growth arrest induced by cell contact has been confirmed, while GNG7 may be involved in this process to prevent growth arrest in multicellular organisms and control cell proliferation [ 19 ]. (biomedcentral.com)
It may function as a cell-type specific modulator for G protein-mediated cell signalling. (embl-heidelberg.de)
Pcp2 (Purkinje cell protein-2) was identified as a partner for Galphao in this system. (embl-heidelberg.de)
Vaccination is an effective strategy to control the spread of SARS-CoV-2, and the protective antibodies induced by the vaccine are known to recognize the viral surface spike (S) protein and primed the T cell response. (sinica.edu.tw)
The study also found that the glycosylation on S protein affected protein folding and T cell response. (sinica.edu.tw)
Cell proteins were analysed with 2-dimensional electrophoresis and differentially expressed proteins were identified by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. (who.int)
protein patterns of subjects with leish- Cell culture maniasis [17]. (who.int)

ABSTRACT In order to define the protein expressional changes related to the process of meglumine antimoniate resistance in anthroponotic cutaneous leishmaniasis (CL), we performed a comparative proteomics analysis on sensitive and resistant strains of Leishmania tropica isolated from Iranian CL patients. (who.int)

References to protein records in UniProtKB are made through entries in the ProForm sub-ontology within PRO (Figure 1 ). (biomedcentral.com)

Our preliminary study using 2D isolates were recovered from liq- new cases throughout the world cu- gel electrophoresis in drug sensitive/ uid nitrogen, and sub-cultured in taneous leishmaniasis (CL) remains resistant strains of L. tropica showed RPMI1640 medium (Gibco/BRL) a serious public health problem in that some proteins were differentially supplemented with 10% fetal bovine numerous countries [1,2]. (who.int)

Anatomy26

Organisms17

Chemicals and Drugs111

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Phenomena and Processes65

Disciplines and Occupations2

Technology, Industry, Agriculture1

Information Science5

Health Care1

Genes7

Heterotrimeric7

Signaling pathway1

Regulatory6

Encodes2

Phosphorylation1

AMPK4

Recombinant9

CGMP-phosphodiesterase2

CDNA1

Months from date of receipt2

Alpha10

Residues2

Homology2

Catalytic1

Nucleotide1

Cytokine5

Receptors11

Binds1

20231

Synthase2

Transmembrane1

Sequence3

Enzyme1

Intracellular1

MRNA4

Kinases5

Mutations3

Manuscript2

Genomic3

Transcript2

Transducin1

Extracellular1

Cellular2

Stability1

Beta-gamma1

Molecule1

Characterization3

Variants2

Human4

Broadly1

Efficacy1

Cells4

Isoforms1

Specificity1

Kinase complex1

Functional2

Mammalian3

Species4

Cascade1

Disulfide1

Complexes4

Signal1

Antigens1

Interactions1

20191

Cell8

Abstract1

UniProtKB1

Bovine1