• A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time. (princeton.edu)
  • Binding of IL-7 to its receptor (IL-7R), which is composed of an α-chain (IL-7Rα) associated to the common cytokine receptor γ (γc) chain ( 12 ), plays a conserved nonredundant role by promoting the survival and proliferation of DN progenitors ( 10 , 13 - 16 ). (rupress.org)
  • Among these factors, FOXA2 was observed to be the most significantly differentially expressed at the hESC-EC day 2 timepoint. (biomedcentral.com)
  • The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. (abnova.com)
  • This cell damage caused by oxidative and nitrosative stress leads to mitochondrial protein, DNA, and lipid modifications, which inhibits energy production and contractile function, potentially leading to cell necrosis and/or apoptosis. (frontiersin.org)
  • The same insults, particularly those related to vascular stress and inflammation also produce elevated levels of nitric oxide, which also has mitochondrial protein thiol-protective functions and induces mitochondrial biogenesis through cyclic GMP-dependent and perhaps other pathways. (frontiersin.org)
  • This assay may also be used to compare the relative performance of the reverse transcription reactions associated with different samples. (bio-rad.com)
  • Control assays and synthetic DNA templates were designed to facilitate the assessment of the key experimental factors impacting your real-time PCR results. (bio-rad.com)
  • In experimental models, this loss in turn inhibited the protein AMPK, an energy sensor of the cell. (eurekalert.org)
  • To account for fiber-type diversity, virtually every contractile protein of muscle fibers exists in different isoforms. (biomedcentral.com)
  • Berto, S. and Nowick, K. (2018) Species-specific changes in a primate transcription factor network provide insights into the molecular evolution of the primate prefrontal cortex, Genome Biology and Evolution 2018 Jul 30. (tu-dresden.de)
  • An important risk factor for atherosclerosis, circulatory disorders and vascular complications is elevated cholesterol. (eurekalert.org)