Pair-rule genes are expressed as a result of differing concentrations of gap gene proteins, which encode transcription factors controlling pair-rule gene expression. (wikipedia.org)
Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells. (riken.jp)
As master transcriptional regulators, Hox proteins recognize DNA through the homeodomain (HD) and interact with a multitude of proteins, including general transcription factors and other cofactors. (biomedcentral.com)
Of particular interest are the protein interactions that occur between Hox proteins and general transcription factors (GTF) from the RNA Pol II basal transcription machinery. (biomedcentral.com)
Here, we focused on the interplay between Antp and the basal transcription machinery and show the direct interaction of Antp with TBP through the poly-glutamine (PolyQ) regions of both proteins. (biomedcentral.com)
Nuclear Factor 90 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
In addition to binding to RNA, nuclear factor 90 proteins form heterodimeric complexes that regulate GENETIC TRANSCRIPTION and may play a role in T-CELL activation. (ouhsc.edu)
In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus. (bvsalud.org)
Transcriptional3
Unfortunately, very few factors have been connected to the transcriptional control of JH synthesis to date. (nature.com)
Transcriptional elongation is a generic function, but is also regulated to allow rapid transcription responses. (sdbonline.org)
They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. (childrensmercy.org)
Genes7
These mutant phenotypes correlate with markedly reduced expression of the early zygotic genes serendipity alpha , fushi tarazu and huckebein , which are essential for cellularization and embryonic patterning (Tang, 2001). (sdbonline.org)
Later work identified more pair-rule genes in the Drosophila early embryo - fushi tarazu, odd-paired and sloppy paired. (wikipedia.org)
Proteína homeótica y factor de transcripción que se localiza en el núcleo celular donde activa la expresión de genes tiroideos específicos como el de la TIROGLOBULINA y el RECEPTOR DE TIROTROPINA. (bvsalud.org)
A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. (bvsalud.org)
In contrast, the Fushi Tarazu homeodomain protein is an activator, both in cultured cells and in Drosophila embryos, where it activates several known target genes, including its own gene. (biologists.com)
Normal Fushi Tarazu target genes are affected as they are in fushi tarazu mutants. (biologists.com)
This plethora of Hox protein-protein interactions clearly points to a Hox-driven transcription process in which every Hox homeoprotein could selectively recruit GTFs to achieve specificity and activate or repress target genes during Drosophila development, although the precise molecular mechanisms remain elusive [ 25 ]. (biomedcentral.com)
Drosophila3
In the dipteran Drosophila melanogaster , TGFbeta signaling stimulates JH production by up-regulating the transcription of the JH acid methyltransferase (JHAMT ) gene through the transcription factor Mothers against Dpp (Mad) 14 . (nature.com)
Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot. (riken.jp)
Metabolism2
They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM. (umassmed.edu)
It regulates GENETIC TRANSCRIPTION involved in METABOLISM of AMINO ACIDS in response to the increased concentration of LEUCINE. (rush.edu)
VIVO1
A derivative that lacks this domain, while it cannot repress the endogenous fushi tarazu gene, can still reduce the activity of the fushi tarazu autoregulatory enhancer, suggesting that it competes with endogenous Fushi Tarazu for binding sites in vivo. (biologists.com)
Here, using the hemimetabolous insect Blattella germanica , we show that nuclear hormone receptors Seven-up-B (BgSvp-B) and Fushi tarazu-factor 1 (BgFTZ-F1) have essential roles in the tissue- and stage-specific activation of adult CA JH-biosynthetic activity. (nature.com)
Scholars@Duke publication: Steroidogenic factor 1 plays multiple roles in endocrine development and function. (duke.edu)
First identified as a tissue-specific regulator of the transcription of the cytochrome P450 steroid hydroxylases, considerably broader roles for SF-1 were revealed by genetic studies in mice lacking SF-1 due to targeted gene disruption. (duke.edu)
Gene transcription2
Loss of FMR2 gene transcription causes mental retardation. (sdbonline.org)
NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription. (ouhsc.edu)
Regulator1
We combined Fushi Tarazu targeting and Engrailed active repression in a chimeric regulator, EFE. (biologists.com)
Descriptor3
p300-CBP Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
Hepatocyte Nuclear Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
Host Cell Factor C1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (rush.edu)
Found primarily1
A family of transcription factors found primarily in PLANTS that bind to the G-box DNA sequence CACGTG or to a consensus sequence CANNTG. (ucdenver.edu)
Cell2
This graph shows the total number of publications written about "Host Cell Factor C1" by people in this website by year, and whether "Host Cell Factor C1" was a major or minor topic of these publications. (rush.edu)
Below are the most recent publications written about "Host Cell Factor C1" by people in Profiles. (rush.edu)
Promoter2
Following relatively long initiation and promoter clearance, RNA polymerase II can pause and then rapidly elongate following recruitment of positive elongation factors. (sdbonline.org)
These novel interactions open the possibility to analyze promoter function and gene expression to measure transcription factor binding dynamics at target sites throughout the genome. (biomedcentral.com)
Celular1
En el CITOPLASMA, las proteínas B I-kappa se unen al factor de transcripción NF-KAPPA B. La estimulación celular causa su disociación y traslocación del NF-kappa B activo al núcleo. (bvsalud.org)
Cells1
Both factors are highly expressed in adult CA cells. (nature.com)
Activity1
In addition to these transcription factors, several peptide hormones (allatotropins, allatostatins and short neuropeptide F) and neurotransmitters (the biogenic amines octopamine, dopamine and glutamate) are also involved in the regulation of CA activity 16 . (nature.com)
Expression3
In the coleopteran Tribolium castaneum , the POU factor Ventral veins lacking/Drifter (vvl) activates JH synthesis during larval stages by activating JHAMT3 expression 15 . (nature.com)
Expression profiles following lilliputian and Suppressor of Triplolethal RNAi were nearly identical raising the possibility that they are obligatory co-factors. (sdbonline.org)
The results showed that ROS and MDA levels were increased, antioxidant system levels were down-regulated, anti-apoptotic factor expression levels were decreased, and apoptotic and necroptosis-related factors were up-regulated after ZAE exposure. (bvsalud.org)
One such target gene is repressed by EFE even where Fushi Tarazu is not expressed, suggesting that the repression is active. (biologists.com)
Activation1
This auto-activation has been shown to depend on targeting to a fushi tarazu enhancer by the Fushi Tarazu homeodomain. (biologists.com)
Human3
Real-world patient-reported outcomes and physician satisfaction with poly (ADP-ribose) polymerase inhibitors versus chemotherapy in patients with germline BRCA1/2-mutated human epidermal growth factor receptor 2-negative advanced breast cancer from the United States, Europe, and Israel. (jefferson.edu)
Real-World Study of Regional Differences in Patient Demographics, Clinical Characteristics, and BRCA1/2 Mutation Testing in Patients with Human Epidermal Growth Factor Receptor?2-Negative Advanced Breast Cancer in the United States, Europe, and Israel. (jefferson.edu)
Real-world study of patients with germline BRCA1/2-mutated human epidermal growth factor receptor 2?Negative advanced breast cancer: Patient demographics, treatment patterns, adverse events, and physician-reported satisfaction in the United States, Europe, and Israel. (jefferson.edu)
Protein4
A transcription factor is a protein that attaches (binds) to specific regions of DNA and helps control the activity of particular genes. (medlineplus.gov)
13. Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene. (nih.gov)
supports the idea that the Runt protein directly regulates transcription. (biologists.com)
Transcription by RNA POL II is bona fide assumed for protein coding genes but must be supported by alpha-amanitin data if the end product is an RNA. (expasy.org)
PROTEINS1
Pair-rule genes are expressed as a result of differing concentrations of gap gene proteins, which encode transcription factors controlling pair-rule gene expression. (wikipedia.org)
Nuclear receptor1
Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. (neobiotechnologies.com)
Adrenal1
Five novel mutations in steroidogenic factor 1 (SF1, NR5A1) in 46,XY patients with severe underandrogenization but without adrenal insufficiency. (medlineplus.gov)
NR5A1 gene variants that cause 46,XY disorder of sex development impair the function of steroidogenic factor 1, though likely to a lesser extent than variants that cause Swyer syndrome (described above). (medlineplus.gov)
Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. (umassmed.edu)
Affects1
The coactivators may act through an enzymatic process that affects the rate of transcription or the structure of chromatin. (nih.gov)
Family1
Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. (childrensmercy.org)
Basic3
Basic Helix-Loop-Helix Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
This graph shows the total number of publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in this website by year, and whether "Basic Helix-Loop-Helix Transcription Factors" was a major or minor topic of these publications. (wakehealth.edu)
Below are the most recent publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in Profiles. (wakehealth.edu)
People1
Below are the most recent publications written about "Hepatocyte Nuclear Factors" by people in Profiles. (childrensmercy.org)
Directly1
provided an initial suggestion that it may be directly involved in regulating transcription in these pathways. (biologists.com)