Furan. Medical search. Frequent questions

Together with the polychlorinated dioxins and furans, these two special classes of PCBs are often referred to as "dioxin-like" chemicals because they act in the body through a similar mechanism. (cdc.gov)
Our High-Resolution Mass Spectroscopy (HRGC-MS) laboratory offers Dioxins and Furans testing, and Poly-Chlorinated Biphenyls (PCB) testing for analysis of stack emissions, ash, soils, and water samples. (element.com)
As highly persistent substances, Dioxins and Furans can also accumulate in many foods, including livestock, and subsequently within the human body. (element.com)
Dioxins and Furans are highly hazardous substances and their release into the atmosphere and presence on land and in water are highly regulated. (element.com)
The UK Element Deeside laboratory is accredited to ISO 17025 and the MCERTS standard for the analysis of stack emission samples for Dioxins, Furans, and Dioxin-like polychlorinated biphenyls (PCB 12). (element.com)
Ash samples are ISO 17025 accredited for Dioxins and Furans and PCB 12. (element.com)
In addition, our experienced experts offer analysis of Dioxins and Furans on water and soil samples. (element.com)
Analyzing samples for Dioxins and Furans requires highly-trained analysts and specialized equipment. (element.com)
For more information about our Dioxins and Furans testing services or to request a quotation, contact us today. (element.com)
APC System Meets Stringent Subpart LLLL Mercury and Dioxins-Furans Emission Limits at Sewage Sludge Incinerator (SSI) in Eastern U.S. (apctechnologies.net)
One SSI in the eastern U.S. - using APC's air pollution control equipment for mercury emissions control, dioxins & furans emissions control, and particulate matter (PM) emissions control - in 2021 became one of the few such 'new' incinerators in the U.S. to comply with the more stringent Subpart LLLL emission limits. (apctechnologies.net)
APC's equipment was guaranteed to meet, and successfully met, the LLLL emission limits for mercury and dioxins & furans coming from the SSI. (apctechnologies.net)
This mercury control system and dioxins-furans emission control system, along with all of APC's other similar systems operating on other SSIs, has a flawless safety and reliability record, provides low operating costs, and requires little maintenance. (apctechnologies.net)
PC's standard air pollution control system offering for SSIs is an activated carbon system, which is long established as the technology of choice where high removal efficiency (i.e., 99%) is needed for mercury removal and dioxins-furans removal. (apctechnologies.net)
APC's mercury, dioxins-furans, and HAPs control systems operating at SSIs collectively have over 30 system-operating years - with a fully safe and high reliability record. (apctechnologies.net)
The term 'furans' is sometimes used interchangeably with 'dioxins. (atamanchemicals.com)
Title : Dioxins, furans and dioxin-like polychlorinated biphenyls Corporate Authors(s) : United States. (cdc.gov)
His scientific research work concerns mainly persistent organic pollutants and other highly toxic compounds, including dioxins, furans, polychlorinated biphenyls, volatile organic compounds and pesticides. (who.int)

The reaction product is a mixture of isomers with preference for the endo isomer: Diels-Alder reaction of furan with arynes provides corresponding derivatives of dihydronaphthalenes, which are useful intermediates in synthesis of other polycyclic aromatic compounds. (wikipedia.org)
Fourteen 2-methyl-3-carboxylnaphtho[2,3-b]furan quinone derivatives (FNQ) were synthesized and evaluated using cultures of Plasmodium falciparum in vitro. (fiocruz.br)
Using the DIN 61198 procedure, it determines furan derivatives dissolved in oil, which can originate from the insulting paper, in 10-ml oil samples. (oelcheck.com)
Among furan derivatives, 2-furaldehyde (furfural) and 5-hydroxymethylfurfural (HMF) constitute the main degradation compounds generated from pentoses and hexoses degradation, respectively. (atamanchemicals.com)
Furan, as well as methyl-substituted furan derivatives, 2-methylfuran and 3-methylfuran, can form in foods through multiple pathways that involve different naturally-present precursor compounds (e.g. polyunsaturated fatty acids, sugars, ascorbic acid) that undergo thermal degradation or chemical rearrangement during food processing. (atamanchemicals.com)
Herein, novel thiophene/furan bridge artemisinin derivatives were synthesized by starting from artemisinin. (ogu.edu.tr)

The ERC identified furan, phenolphthalein, furfuryl alcohol, and tetrahydrofuran as having low potential to cause ecological harm. (canada.ca)
Considering all available lines of evidence presented in this draft screening assessment, there is low risk of harm to the environment from furan, phenolphthalein, furfuryl alcohol, and tetrahydrofuran. (canada.ca)
In this context, ASK Chemicals has developed MAGNASET as new generation of furan resins with reduced free furfuryl alcohol content featuring a milder classification and a performance comparable to conventional furan resins. (foundry-planet.com)
In contrast to phenolic-urethane or ester-curing phenolic systems, which are based on petrochemical components, furan binders are based on furfuryl alcohol, which is a readily available renewable raw material derived from agricultural waste such as corn husks or rice hulls. (foundry-planet.com)

3α * -tert-Butyl-4-(2-methoxy-1-naphthyl)naphtho[2,3-c]furan-1(3H)-one" Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking science and technology information which hitherto stood alone to support the generation of ideas. (go.jp)
6b,11b-Dihydroxy-6b,11b-dihydro-7H-indeno[1,2-b]naphtho[2,1-d]furan-7-one (DHFO), an easily synthesisable, orally bioavailable and relatively non-toxic small molecule synthesised in our lab, was previously reported to possess anti-oxidant, 5-lipoxygenase inhibitory, anti-inflammatory and peripheral analgesic activities. (monash.edu)

The Feist-Benary synthesis is a classic way to synthesize furans. (wikipedia.org)
Many routes exist for the synthesis of substituted furans. (wikipedia.org)
A Br nsted acid-catalyzed one-pot synthesis of indoles from o -aminobenzyl alcohols and furans via in situ formation of aminobenzylfuran followed by its recyclization into the indole core proved to be efficient for a wide range of substrates. (organic-chemistry.org)
Synthesis of Thiophene/Furan-Artemisinin. (ogu.edu.tr)

Furan is a colorless, flammable, highly volatile liquid with a boiling point close to room temperature. (wikipedia.org)
Furan is a colorless, volatile, liquid. (atamanchemicals.com)
Furan is a clear, colorless, flammable liquid cyclic ether with an ethereal odor. (atamanchemicals.com)
Furan appears as a clear colorless liquid with a strong odor. (atamanchemicals.com)
Furan is a colorless, volatile liquid used in some chemical manufacturing industries. (atamanchemicals.com)

Exposure to furan at doses about 2,000 times the projected level of human exposure from foods increases the risk of hepatocellular tumors in rats and mice and bile duct tumors in rats. (wikipedia.org)
Food is expected to be the primary source of exposure to furan for Canadians. (canada.ca)
According to a study published by EFSA (European Food Safety Authority) "Update on furan levels in food from monitoring years 2004-2010 and exposure assessment" furan levels of the tested coffee products were higher than furan levels of other food categories. (qsi-q3.com)
Based on the above results, it is suggested that exposure to food -based contaminant furan induced remarkable changes in the F0 (parental stage) and F1 (offspring, pubertal, and adult stage) generations of Sprague Dawley rats . (bvsalud.org)

Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ring with four carbon atoms and one oxygen atom. (wikipedia.org)

The name "furan" comes from the Latin furfur, which means bran (furfural is produced from bran). (wikipedia.org)
Industrially, furan is manufactured by the palladium-catalyzed decarbonylation of furfural, or by the copper-catalyzed oxidation of 1,3-butadiene: In the laboratory, furan can be obtained from furfural by oxidation to 2-furoic acid, followed by decarboxylation. (wikipedia.org)
Furfural, derived from sugars, is the major source of furans methanofuran is a cofactor in methanogenesis. (wikipedia.org)

Furan has been classified as possibly carcinogenic for humans by the International Agency for Research on Cancer (IARC), therefore the intake by humans should be as low as possible. (qsi-q3.com)

The Committee made recommendations on the risks to health associated with six important contaminants in food (acrylamide, arsenic, deoxynivalenol, furan, mercury, and perchlorate). (who.int)
Health concerns relating to current estimated levels of intake were identified for acrylamide, arsenic and furan. (who.int)

For the first time, the spatial distributions of the highly volatile compounds furan and 5-hydroxymethylfurfural (HMF) have been determined in cross sections of green and roasted Coffea arabica beans. (unboundmedicine.com)

Furan itself was first prepared by Heinrich Limpricht in 1870, although he called it "tetraphenol" (as if it were a four-carbon analog to phenol, C6H5OH). (wikipedia.org)

We report a novel catalytic conversion of biomass-derived furans and alcohols to aromatics over zeolite catalysts. (nih.gov)

Pursuant to section 68 or 74 of the Canadian Environmental Protection Act, 1999 (CEPA), the Minister of the Environment and the Minister of Health conducted a screening assessment of four of five substances referred to collectively under the Chemicals Management Plan as the Furan Compounds Group. (canada.ca)
The ecological risks of the substances in the Furan Compounds Group in this assessment were characterized using the ecological risk classification of organic substances (ERC). (canada.ca)

Furan is also used as a solvent for resins and as a reactant/intermediate in the production of agricultural chemicals and pharmaceuticals, but was not identified in products available to consumers. (canada.ca)

Thus, these heterocycles, especially furan, are far less aromatic than benzene, as is manifested in the lability of these rings. (wikipedia.org)

BS 4994 - Furan resin as thermoset FRP for chemical process plant equipments Furanocoumarin Furanoflavonoid Furanose Furantetracarboxylic acid Simple aromatic rings Furan fatty acids Tetrahydrofuran Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). (wikipedia.org)
Furan is usually converted by hydrogenation to tetrahydrofuran, which is used as a solvent and for production of adipic acid and hexamethylenediamine, the raw materials for nylon-6,6. (atamanchemicals.com)
Starting with an ε-lactone, which is α,β-unsaturated in trichilinones A and D (1 and 4), attached to a tetrahydrofuran ring that is connected to an unusual bicyclo [5.1.0] hexane system, joined with a cyclopentanone with a 3-furanyl substituent [(2-oxo)-furan-(5H)-3-yl in trichilinone D (4)], the four compounds isolated display a new 7/5/3/5/5 limonoid ring system. (lu.se)

Hydrogenation of furans sequentially affords dihydrofurans and tetrahydrofurans. (wikipedia.org)

Chemical compounds containing such rings are also referred to as furans. (wikipedia.org)
The class of compounds containing such rings is also referred to as furans. (atamanchemicals.com)

The aim of this review is to explore the use of polar organic solvents in the process of the manufacture of furans, while addressing the challenges of its industrial application, particularly in solvent recovery and recycling. (utwente.nl)
Furan is soluble in common organic solvents, including alcohol, ether, and acetone, and is slightly soluble in water. (atamanchemicals.com)
Furan or furfuran is a heterocyclic aromatic organic compound. (atamanchemicals.com)
Furan is a mancude organic heteromonocyclic parent, a member of furans and a monocyclic heteroarene. (atamanchemicals.com)
Furan, any of a class of organic compounds of the heterocyclic aromatic series characterized by a ring structure composed of one oxygen atom and four carbon atoms. (atamanchemicals.com)
Furan belongs to the class of organic compounds known as heteroaromatic compounds. (atamanchemicals.com)
Furan is a colourless, volatile organic compound that is used in some chemical manufacturing industries and may also be found in low levels in some foods, most notably in foods that undergo thermal treatment such as canning or jarring. (atamanchemicals.com)

Furan has aromatic character because one of the lone pairs of electrons on the oxygen atom is delocalized into the ring, creating a 4n + 2 aromatic system (see Hückel's rule). (wikipedia.org)
Furan is aromatic because Furan obeys the 4n+2 electron system rule. (atamanchemicals.com)

Portions of this work were presented as follows: Brus LA, Lu D, and Peterson LA (2011) Oxidation of furan to a reactive metabolite by human cytochrome P450 enzymes. (aspetjournals.org)

Pyrrole can be prepared industrially by treating furan with ammonia in the presence of solid acid catalysts, such as SiO2 and Al2O3. (wikipedia.org)
Manufacturing furans employs the use of mineral acid catalysts (e.g. (utwente.nl)

Furan serves as a diene in Diels-Alder reactions with electron-deficient dienophiles such as ethyl (E)-3-nitroacrylate. (wikipedia.org)
Synchrotron-diffraction experiments and proton-affinity calculations clearly suggest that a preferred protonation of ethanol over the furan is a key step facilitating the Diels-Alder and dehydration reactions in the acid sites of the zeolite. (nih.gov)

citation needed] In the Achmatowicz reaction, furans are converted to dihydropyran compounds. (wikipedia.org)

Research has indicated that coffee made in espresso makers and coffee made from capsules contain more furan than that made in traditional drip coffee makers, although the levels are still within safe health limits. (wikipedia.org)
This approach limits the selectivity towards furans to approx. (utwente.nl)
Up to date there are no legal limits or indicative values for furan in foods. (qsi-q3.com)

Effects of endocrine disruptor furan on reproductive physiology of Sprague Dawley rats: An F1 Extended One-Generation Reproductive Toxicity Study (EOGRTS). (bvsalud.org)
The present study investigated the reproductive toxicity of furan in an Extended One-Generation Reproductive Toxicity Study in rats . (bvsalud.org)
Sprague Dawley F0 weaning rats (30 per sex per group) were exposed to furan orally at 0, 1, 2.5, 5, and 10 mg kg-1 for 10 weeks ( males ) and 2 weeks ( females ) and then mated. (bvsalud.org)
At postnatal day (PND) 70, a significant (p = 0.03) decrease in testosterone levels of male rats and estrogen levels of female rats (p = 0.05) was observed in 10 mg kg-1 furan-treated group in F1 generation. (bvsalud.org)

Furan is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. (atamanchemicals.com)

Furan is used as a starting point for other speciality chemicals. (wikipedia.org)
ASK Chemicals has a strong background in Furan NoBake (FNB) chemistry and provides customer-made solutions based e.g., on their signature product ASKURAN for several decades. (foundry-planet.com)

The first furan derivative to be described was 2-furoic acid, by Carl Wilhelm Scheele in 1780. (wikipedia.org)
The first furan compound discovered was pyromucic acid (2-furoic acid), prepared in 1780. (atamanchemicals.com)

The image maps were revealed by laser ablation DART imaging mass spectrometry (LADI-MS). The presence of these compounds was independently confirmed by GC-MS as well as argon DART-MS. Quantification of furan by GC-MS was completed with the final concentrations in roasted and unroasted beans determined to be 96.5 and 4.1 ng/g, respectively. (unboundmedicine.com)
Furan was observed to be distributed throughout the tissue of both green and roasted beans, while HMF was localized to the silver skin in green beans. (unboundmedicine.com)
But furan contents in coffee strongly depend on the category of coffee (for example whole roasted beans or grinded beans) and the way of brewing. (qsi-q3.com)
According to the above mentioned study published by EFSA furan levels of up to 6407 µg/kg are possible for roasted whole coffee beans. (qsi-q3.com)
In average the tested roasted whole coffee beans contained about 3660 µg/kg furan. (qsi-q3.com)
Studies show that grinding of roasted whole coffee beans leads to a reduction of furan levels of up to 40 % in grinded coffees compared to the whole beans. (qsi-q3.com)

For Stack Emission Sampling , Element Deeside provides prepared and spiked XAD-2 resin traps, GFA filters, and glass bottles that comply with sampling to BS EN 1948. (element.com)

The simplest member of the furan family is furan itself, a colourless, volatile, and somewhat toxic liquid that boils at 31.36° C (88.45° F). (atamanchemicals.com)

Amino acids and sugars are believed to play a key role in the formation of furan in foods. (qsi-q3.com)

At the current time the total intake of furan through foods cannot be estimated. (qsi-q3.com)

Furan is a volatile substance (boiling point approx. (qsi-q3.com)

Degradation problem under the resistance generation that the long-term use of furans worm hydrazides list agent may bring, the drug effect, the Pesticidal combination that the present invention proposes contains two kinds of active components of A, B, and an amount of surfactant and carrier. (google.com)
A kind of Pesticidal combination that contains furans worm hydrazides and amides compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: active components A, B ratio of weight and number are 1: 60～60: 1, described active components A is selected from furans worm hydrazides, and active component B is selected from a kind of in fipronil bisamide, the Rynaxypyr. (google.com)
Often, product streams (e.g. glucose) still contain small amounts of undesired components (e.g. furans such as HMF). (tue.nl)

Several other members of the furan family are produced on a large scale for use as solvents and chemical raw materials. (atamanchemicals.com)

Darker roasted coffees, with longer roasting times (for example Espresso) are tending to have higher furan levels than lighter roasted coffees. (qsi-q3.com)

Furan is found in heat-treated commercial foods and is produced through thermal degradation of natural food constituents. (wikipedia.org)
Furan is a volatile (boiling point = 31.4°C) cyclic ether found in cigarette smoke. (atamanchemicals.com)
Furan has occasionally been reported to be found in foods. (atamanchemicals.com)
Furan is found in heat-treated (e.g. cooked, roasted, baked, pasteurized, and sterilized) commercial foods and is produced through thermal degradation of natural food constituents. (atamanchemicals.com)
Furan has also been found in further heat-treated foods like bread or canned vegetables and canned meat. (qsi-q3.com)

Furan can be formed in foods during heat treatment, for example during coffee roasting. (qsi-q3.com)
Therefore further data on the occurrence of Furan in different foods needs to be collected. (qsi-q3.com)
Furan in foods is a topic of increasing interest. (qsi-q3.com)

In higher dose furan group (10 mg kg-1), testicular and ovarian weights were reduced in F1 generation at PND 70, with decreased daily sperm production (p = 0.01) and disturbed estrous cyclicity (p (bvsalud.org)
Some histopathological changes were also observed in testis and ovaries in groups whose parents were previously exposed to 10 mg kg-1 bw of furan group. (bvsalud.org)

Furan is released to air as a gas phase component of cigarette smoke, wood smoke and exhaust gas from diesel and gasoline engines. (canada.ca)

32 °C), due to that furan volatilizes during brewing of coffee with hot water. (qsi-q3.com)

La sensibilisation et la formation du personnel, le tri des déchets médicaux solides et la mise en place d'installations de traitement simples sont les principales mesures suggérées pour améliorer les pratiques de gestion des déchets. (who.int)

Furan is a small family run Guest House offering value for money, quality and comfortable modern accommodation. (visitscotland.com)

The loss of furan during brewing of coffee depends on the kind of coffee preparation, preparation in a closed system, for example in fully automatic coffee machines, can be expected to lead to higher furan levels in the brew than preparation in open systems. (qsi-q3.com)
According to studies furan levels in brewed coffee are approximately 50-90 % lower than in roasted coffee. (qsi-q3.com)
Due to that we recommend to monitor furan levels of roasted coffees. (qsi-q3.com)

In recent years, this technology has been referred to as New Furan Technology (NFT). (foundry-planet.com)

This study focuses on the removal of furans produced during the fermentation. (tue.nl)

Run by Janice and Kevin since March 2007, Furan offers a comfortable haven for business people or visitors alike. (visitscotland.com)

Internal inspection of the transformer is only carried out if elevated furan values signal the need for action. (oelcheck.com)

In addition 'furans' refers to a large class of compounds of widely varying structures including, for example, nitrofurans. (atamanchemicals.com)

Furan in nature and commerce The drug Zantac, also known as ranitidine. (wikipedia.org)

Furan has a strong ethereal odour. (atamanchemicals.com)

Diseases1

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes4

Technology, Industry, Agriculture1

Dioxins18

Derivatives6

Furfuryl alcohol4

Naphtho2

Synthesis4

Colorless5

Exposure4

Heterocyclic organic1

Furfural3

Carcinogenic1

Acrylamide2

Volatile compounds1

Phenol1

Alcohols1

Substances2

Resins1

Benzene1

Tetrahydrofuran3

Hydrogenation1

Compounds containing2

Organic7

Aromatic2

Oxidation1

Catalysts2

Diels-Alder2

Reaction1

Limits3

Rats4

Formula1

Chemicals2

Acid2

Beans6

Emission1

Toxic1

Sugars1

Intake1

Approx1

Components3

Chemical1

Espresso1

Found5

Foods3

Group2

Exhaust1

Water1

Formation1

Family1

Levels3

Technology1

Study1

Offers1

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Strong1