• The essential biochemistry, genetics, cell biology, and metabolic pathways underlying the survival and success of all living organisms. (queensu.ca)
  • In RIT's biotechnology and molecular biology degree you'll improve human health by harnessing technology advancements and biomolecular processes to research and develop technologies in genetics, agriculture, pharmaceuticals and vaccine development, environment and energy, forensic science, genetic counseling, and more. (rit.edu)
  • Students may elect to work on research projects with faculty who work in the areas of food microbiology, immunology, microbial genetics, and molecular biology. (mnsu.edu)
  • Study of biological processes at the suborganismal level including cell chemistry, metabolism, reproduction, genetics, and complex tissue physiology. (mnsu.edu)
  • Kim lab takes advantage of cutting-edge approaches including advanced genetics, microscope imaging, biochemical and cell biological techniques using Drosophila (fruit flies) as model system. (unr.edu)
  • This course element will introduce you to the fundamental principles of medically related cell biology and molecular and clinical genetics. (le.ac.uk)
  • The bulk of her scientific training, in fact, took place in molecular biology and genetics departments. (rockefeller.edu)
  • Because of its mutated aggressive genetics, this cell has a selective growth advantage over its neighbors. (medscape.com)
  • For a researcher armed with the powerful tools of genetics and molecular biology, the simple bacterial cells provide great experimental systems for investigating fundamental functions of a living cell. (lu.se)
  • Human induced pluripotent stem (hiPS) cells and hiPSell-derived organoids are model systems ripe for realizing the need for diversity in ancestral background and sex in human biomedical research. (nature.com)
  • The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. (wikipedia.org)
  • The metabolism of cancer cells is also different from the metabolism of normal cells, and these differences can be used to find targets for therapeutic intervention in cancer. (wikipedia.org)
  • Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
  • Your second year builds on this knowledge and covers areas such as gene regulation, cell biology and metabolism. (kent.ac.uk)
  • RNA synthesizes the panoply of proteins that an organism requires to live and works to regulate cell metabolism. (yahoo.com)
  • RNA sequencing gives you a taste of the real biology and metabolism regulation that was happening in the cells and tissues of the Tasmanian tigers before they went extinct,' said geneticist and bioinformatician Emilio Mármol Sánchez of the Centre for Palaeogenetics and SciLifeLab in Sweden, lead author of the study published in the journal Genome Research. (yahoo.com)
  • Scientists working in basic, translational, and clinical cancer metabolism research are invited to join the Academy in New York on April 17th to discuss the intersection between cell signaling and metabolism. (nyas.org)
  • Cancer Cell Metabolism: Unique Features Inform New Therapeutic Opportunities. (nyas.org)
  • Cell Metabolism, 29, 202-210. (lu.se)
  • Methodologies include cell and molecular biology, biochemistry, and microscopy - combined with proteomics to examine cell physiology, inter and intracellular signalling, cell structure, and organelle function, both on a cellular and molecular level. (edu.au)
  • In your first year, your modules give you an insight into various biological and chemical disciplines, including biochemistry, cell and molecular biology, microbiology and physiology. (kent.ac.uk)
  • This course element will cover the medically and clinically related fundamental principles of cellular and molecular physiology that form the basis for the understanding of pharmacology (use of drugs to treat human disease). (le.ac.uk)
  • A key aspect to our physiology is how all the small parts come together, e.g. cytoskeleton, focal adhesions, cell-cell contacts, cell membrane, etc. (washington.edu)
  • Through studying the coordinated activity of cells and quantifying their mechanical properties, we can understand normal and diseased physiology at a fundamental level. (washington.edu)
  • We found that C3 regulates process of autophagy and cell survival upon stress and now we aim to investigate what role C3 may play in β-cell physiology and islet inflammation. (lu.se)
  • We strive for a detailed understanding of the interactions between cells and nanostructures with respect to cell behavbehaviourl physiology and cell mechanics. (lu.se)
  • It also prepares a student for continuing education in microbiology, immunology, and cell and molecular biology. (mnsu.edu)
  • Flow cytometry have important applications in many fields including fundamental and applied microbiology, bioprocess monitoring, protein engineering, plant biology and marine biology. (lu.se)
  • Many students that graduate from the programme dation of knowledge and general y important skil s in microbiology continue with PhD studies in biomedical research or other fields and molecular biology. (lu.se)
  • Within the programme, you can specialise related to microbiology or molecular biology. (lu.se)
  • Other proteins have structural or mechanical functions, such as those that form the cytoskeleton, a system of scaffolding that maintains the cell shape. (wikipedia.org)
  • Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes, and the cell cycle. (wikipedia.org)
  • BAFF-R is one of the receptors for B-cell activating factor (BAFF), a member of the TNF family of proteins. (bdbiosciences.com)
  • By miniaturizing the tool, we can probe the role of cell mechanics at the length scale appropriate to the size of cells and their proteins. (washington.edu)
  • Our bodies can be viewed as a hierarchical system where our organs are composed of different tissues, which are defined by cells and the properties of the proteins they express. (washington.edu)
  • Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд. (wikipedia.org)
  • First, we characterized the cell surface receptors for matrix proteins on stem cells and identified specific proteins that will support adhesion and growth of the cells. (ca.gov)
  • Second, using an interdisciplinary approach, we developed a novel method to screen peptides from these proteins for their ability to support adhesion and proliferation of the stem cells. (ca.gov)
  • Based on our characterization of cell surface receptors for matrix proteins on stem cells completed in the first year, we went on to test specific, purified proteins that will support adhesion and growth of the cells. (ca.gov)
  • Processes like these have evolved from common ancestors of both eukaryotes and prokaryotes, and it becomes increasingly clear that the bacterial versions of these basic cell functions use similar ancestral molecules, for example cytoskeletal proteins, as those used in animal and plant cells. (lu.se)
  • They would aim to replace the genomically unstable cancer cell lines that are commonly used in research 10 with replicating diploid cells that differentiate into many kinds of cell types and tissues. (nature.com)
  • As these molecules are vital for life, metabolic reactions either focus on making these molecules during the construction of cells and tissues, or on breaking them down and using them to obtain energy, by their digestion. (wikipedia.org)
  • Moreover, these properties and responses can serve as mechanical signatures that allow us to diagnose diseased states in our cells and tissues. (washington.edu)
  • Cancer cells invade into healthy tissues and co-opt these tissues into promoting tumor growth and metastasis. (jhu.edu)
  • I began to think about the physical processes cells and tissues undergo as a fundamental guiding principle for developmental biology," she says. (rockefeller.edu)
  • Understanding how stem cells behave in the niche is extremely important in order to extract these cells from their natural habitat, expand them in vitro and transplant the stem cells back to the patient, to repair and/or regenerate tissues and organs, with no risks to the individual's integrity. (bvsalud.org)
  • Likewise, the knowledge of stem cell biology is crucial to the development of stem cell therapies, based on tissue engineering applied to dentistry, seeking the regeneration of dental tissues damaged or lost by caries, trauma or genetic diseases. (bvsalud.org)
  • Therapies based on the application of stem cells have great potential in the prevention and treatment of several diseases, such as cancer, diabetes, cardiovascular disease, spinal cord injuries, neurological diseases such as Parkinson's and Alzheimer's, and in the regeneration of various tissues and organs. (bvsalud.org)
  • All tissues and organs are made of billions of different cells. (msdmanuals.com)
  • Tissues and Organs Tissues are related cells that are joined together. (msdmanuals.com)
  • The origin and roles of sperm cell dynamics in reproductive tracts remain less than well-understood despite their physiological importance (2022, Semin Cell Dev Biol). (timeshighereducation.com)
  • I have been teaching a variety of courses here at Queen's for over 20 years, from introductory biology to the commercialization of biological research at the graduate level. (queensu.ca)
  • The cell forms the fundamental basis of all the biological sciences and life. (kopykitab.com)
  • Their main structural uses are as part of biological membranes both internal and external, such as the cell membrane. (wikipedia.org)
  • This course investigates the historical framework of evolutionary biology and the meaning/nature of evidence pertinent to biological evolution. (rit.edu)
  • Dr. Hirashima's research group is interested in how collective cell behaviour emerges and how it relates to biological functions in development and reproduction. (timeshighereducation.com)
  • O ur mission is to understand how mechanics affects human biology and disease at the fundamental level of biological cells. (washington.edu)
  • Chemical equilibria are fundamental in the understanding of biological and environmental processes and in chemical analysis. (beloit.edu)
  • Included are enzymatic action, transport across biological membranes, and basic metabolic pathways as they relate to cell structure. (bethanywv.edu)
  • We propose that a suite of well-characterized hiPS cell lines with ancestral and sex diversity would become a benchmarked collection of cell lines for basic science and studies of disease mechanisms, and for the introduction of disease mutations and performance of screens for novel therapeutics. (nature.com)
  • Students in this course will gain an understanding of various molecular mechanisms, structure/function relationships, and processes as they relate to molecular biology. (rit.edu)
  • In this project, the group will combine live cell imaging, microfluidic devices, and mathematical modelling to further explore the fundamental mechanisms of how collective sperm dynamics emerge and link to reproductive functions and aging. (timeshighereducation.com)
  • The overarching goal of the Systems Biology Laboratory is to apply modern methods of biomedical engineering to better understand the mechanisms of cancer and to significantly advance treatments for this devastating disease. (jhu.edu)
  • This work aimed to uncover new regulatory mechanisms in the cell that may have broad impact in the understanding of how protein synthesis is regulated. (europa.eu)
  • [ 6 ] These events lead the cancer cell to escape normal cell growth and control mechanisms, to avoid system control mechanisms (ie, immunologic surveillance), and to establish a nutrient supply. (medscape.com)
  • Thus, these organisms are of a huge industrial and medical importance, and an improved understanding of their biology, growth habits, regulatory mechanisms, and cell differentiation will greatly facilitate the exploration of streptomycetes in various industrial and biotechnological applications. (lu.se)
  • You will gain hands-on experience in planning and conducting laboratory experiments that address fundamental cellular mechanisms underlying physiological and disease processes. (lu.se)
  • Our goal is to gain a better understanding of the underlying mechanisms and implications of C3 and CD59 in pancreatic β-cell function and diabetes. (lu.se)
  • We aim to investigate the molecular mechanisms responsible for these novel functions of COMP, particularly those related to basic cell biology and tumor immunology. (lu.se)
  • Unravelling fundamental cellular mechanisms for use in biomedical applications. (lu.se)
  • Our objective is to unravel fundamental dynamic neural and glial mechanisms underlying learning-related altered neural network structures and information processing in conscious individuals using implantable and biocompatible nanostructured neural interfaces. (lu.se)
  • A particular focus is on the development of nanomaterial probes for elucidating fundamental cellular processes and characterizing nanoparticle - cell interactions. (bu.edu)
  • It tackles the complex phenomena of living things and explores the fundamental interactions between molecules, cells, organisms and their communities. (uni-stuttgart.de)
  • This approached turned out to be surprisingly fruitful: the group showed that mechanical interactions within tissue are critical to the emergence of not only loops, but also villi and stem cell niches in the gut. (rockefeller.edu)
  • At these sites, which are a compound of stromal cells, extracellular matrix and soluble factors, complex molecular interactions that maintain the essential properties of stem cells occur, such as self-renewal and differentiation into multiple lineages, according to the organism's needs. (bvsalud.org)
  • These libraries should include standardized, reproducible and openly shared protocols for cell growth and differentiation, tools for their use and study, and baseline data on phenotypes, genomics and cell organization. (nature.com)
  • BAFF is a key regulator for B cell differentiation and critical in regulating survival and activation of peripheral B cell populations. (bdbiosciences.com)
  • In addition, we examined whether these substrates will support differentiation of retinal pigmented epithelial cells, an important, clinically relevant cell type that is currently in clinical trials for eye disease. (ca.gov)
  • This surface proved to be efficient at supporting growth of undifferentiated hESC as well as differentiation of useful cell types. (ca.gov)
  • There is a critical need for new technologies to facilitate growth and differentiation of human embryonic stem cells (hESC) using clinically acceptable, animal-free reagents. (ca.gov)
  • The wider question that we want to understand is how molecules of a cell govern such essential and complex functions like cell division, cell polarity, determination of cell shape, and cell differentiation. (lu.se)
  • My scientific background is in soft matter, with my doctoral work focusing on the fundamental physics of electrically-charged polymers at the solid-liquid interface. (imperial.ac.uk)
  • Physics explores the most fundamental measurable quantities of energy and matter and. (mcgill.ca)
  • These include scanning electrochemical cell microscopy (SECCM), which is opening up new nanoscale views of electrochemical interfaces, scanning electrochemical microscopy (SECM), new modes of scanning ion conductance microscopy (SICM) and various hybrid techniques, such as combined SECM-SICM and other methods. (warwick.ac.uk)
  • We are also applying advanced microscopy, which in recent years has revolutionized the understanding of prokaryotic cells and visualized the remarkable degree of three-dimensional organization, complexity, and beauty of these deceivingly simple organisms. (lu.se)
  • The projects feature state-of-the-art methods for the investigation of cell biology, such as flow cytometry and confocal microscopy, protein interaction analyses using the proximity-ligation assay and Biacore, and genetic manipulation employing the Cas9/CRISPR system. (lu.se)
  • We seek to understand how cells work, and how disease processes alter those functions. (edu.au)
  • Our work aims to investigate whether the processes that regulate the tRNA availability in the cell are specific and how they can affect protein translation and directly impact cell fitness. (europa.eu)
  • these processes occur over two main phases of the cell cycle. (jove.com)
  • Studies the structural organization and chemical compositions of cells and fundamental chemical processes carried on inside organelles. (bethanywv.edu)
  • The model organisms that we use, Gram-positive bacteria of the genus Streptomyces , provide unique possibilities to study some of these fundamental functions, and show several intriguing parallels to the corresponding processes in eukaryotic cells. (lu.se)
  • Cell proliferation will probably be detected by numerous methods. (bioinfor.me)
  • Cell proliferation induces an increase throughout the train of the mitochondrial dehydrogenases, which cleaves the tetrazolium salt to formazan. (bioinfor.me)
  • The WST Cell Proliferation Colorimetric Assay Package deal plus provides one of the best and most delicate technique for quantification of cell proliferation and viability. (bioinfor.me)
  • Cell proliferation causes the rise throughout the amount of formazan dye normal that is straight proportional to the number of residing cells and will probably be quantified by measuring the absorbance of the dye decision at 440 nm using microtiter plate reader. (bioinfor.me)
  • The gear may be utilized for the analysis of cell proliferation in response to pharmaceutical compounds, cytotoxic compounds like anticancer drugs and many totally different toxic brokers. (bioinfor.me)
  • The assay may be used for the detection of cell proliferation in response to cytokines, mitogens, progress parts and nutritional vitamins, and so forth. (bioinfor.me)
  • Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal most cancers cells by the use of upregulation of the microRNA-34a/449a cluster. (bioinfor.me)
  • Mice injected with BAFF-neutralizing-Fc (BAFF-R-Fc) protein showed reduced NF-κB activation, blocking BAFF-induced B cell proliferation. (bdbiosciences.com)
  • We proposed to develop novel, well-defined, synthetic extracellular matrices that support survival and proliferation of human embryonic stem cells. (ca.gov)
  • In 1986, he joined the laboratory of William A. Haseltine at the Dana-Farber Cancer Institute and Harvard Medical School as a postdoctoral fellow, working on fundamental aspects of HIV structure and function to uncover new targets for antiviral therapy. (wikipedia.org)
  • Students complete a foundational course in molecular biology and the accompanying laboratory course and then go on to study additional cellular and molecular biology subjects in more detail. (rit.edu)
  • This laboratory course will address the fundamental concepts of Molecular Biology. (rit.edu)
  • Students in this laboratory will complement their understanding of core concepts in Molecular Biology through the implementation and practice of laboratory techniques used by Molecular Biologists. (rit.edu)
  • our laboratory is at the cutting edge of the cancer systems biology research. (jhu.edu)
  • The work in Dr. Eirin's laboratory has immediate impact on patient care at Mayo Clinic by improving the understanding of the contribution of these organelles to stem cell function. (mayo.edu)
  • He developed the chromosome conformation capture technologies, biochemical techniques for determining how DNA segments interact and are linked to one another, which are the heart of the "3C," "5C," "Hi-C" and "Micro-C" tools used by researchers worldwide to map the structure and organization of chromosomes inside cells. (umassmed.edu)
  • During the M phase, the duplicated chromosomes are separated and distributed to two genetically identical daughter cells. (jove.com)
  • Researchers from Johns Hopkins Medicine have discovered that the organization of different types of immune cells within pancreatic tumors is associated with how well patients with pancreatic cancer respond to treatment and how long they survive. (jhu.edu)
  • Flow cytometry is used for single-cell analysis of cell populations and monitoring of population phenotypic heterogeneity as well as for preparative sorting of individual cells and subpopulations. (lu.se)
  • Focus of the course will be on getting practical experience of flow cytometry for single-cell analysis and cell sorting of microorganisms. (lu.se)
  • You also choose two optional modules from a range that covers areas such as the biology of ageing, cancer biology and neuroscience. (kent.ac.uk)
  • Using chromosome conformation capture technologies in conjunction with advanced computational modeling and a range of imaging methods, the center will generate three-dimensional models of the human genome inside fibroblast cells during metaphase and interphase, as well as in embryonic stem cells in undifferentiated and differentiated states. (umassmed.edu)
  • Finally, we identified a cyclic RGD peptide that supports growth of human embryonic stem cells. (ca.gov)
  • Cancer is characterized by uncontrolled growth and division of a cell, with extension beyond the normally limiting basement membrane and through the boundaries of normal cells. (medscape.com)
  • Oxidation of CL in response to silica is followed by the accumulation of the hydrolyzed moiety of CL, monolyso-CL, and oxidized free fatty acids shortly after the release of cyt C, and the externalization of PS in the cell membrane. (cdc.gov)
  • The additional capital will support Vittoria's clinical development initiatives and advance its next-generation cell therapies that strengthen efficacy, improve safety, and broaden therapeutic applicability for patients with cancer and autoimmune diseases. (tmcnet.com)
  • We're thrilled to partner with such esteemed and diverse institutions in our efforts to address some of the most persistent barriers in the cell therapies space," said Nicholas Siciliano, Ph.D., Chief Executive Officer of Vittoria. (tmcnet.com)
  • Senza5 is designed to maximize stemness, durability and efficacy of its produced cell therapies by disabling the CD5 signaling pathway on engineered CAR-T cells, and bypassing CD5's immunosuppressive effects to amplify the therapy's antitumor activity. (tmcnet.com)
  • By acting on the fundamental biology of T cells, Senza5 can be widely utilized to improve the efficacy of engineered T-cell therapies. (tmcnet.com)
  • We're proud to invest in Vittoria Biotherapeutics to support the innovative Senza5 platform technology and VIPER-101 program, recognizing there is a need for safer and more effective therapies for T-cell lymphoma patients," said Lore Gruenbaum, Ph.D., Vice President, LLS TAP. (tmcnet.com)
  • Our investment in Vittoria Biotherapeutics underscores our belief in their groundbreaking approach to engineered T-cell therapies and our confidence in the management team to execute on their vision. (tmcnet.com)
  • By acting on the fundamental biology of T cells, Senza5 can be used to improve the efficacy of engineered T cell therapies with pipeline applications in oncology and autoimmune diseases. (tmcnet.com)
  • This is an important, unmet need in the field and development of such a substrate would aid in moving stem cell therapies to the clinic. (ca.gov)
  • However, further studies are required to gain complete understanding of stem cell biology, which is fundamental for the development of successful cell-based therapies 1-3 . (bvsalud.org)
  • We study the immune system of infected people and animal hosts to determine how dangerous viruses infect and spread within cells of the body to guide the design of effective human antiviral therapies, treatments, and other control/intervention measures. (cdc.gov)
  • Most cancers Cell Int. 2021 Jan 6;21(1):14. (bioinfor.me)
  • Understanding mitosis is a major aim of fundamental molecular cell biology but is also vitally important for understanding cancer and stem cells. (gla.ac.uk)
  • Your project will be an important part of our lab's work to understand how the mass of nuclear RNA in a cell affects mitosis. (gla.ac.uk)
  • This image shows an example from our lab of a cell in the prometaphase of mitosis. (gla.ac.uk)
  • This is all typical of mitosis: the same as you would see in many cell lines. (gla.ac.uk)
  • To avert this potential crisis, the cell devotes a substantial amount of energy during early mitosis to gradually reorganizing the sister chromatids into shorter structures that separate more easily. (jove.com)
  • It aims to address fundamental questions about the origin, evolution, development, and behaviour of living organisms. (mcgill.ca)
  • The viability, plasticity, proliferative and differential potential, and functionality of stem cells are all affected by the function and integrity of their mitochondria. (mayo.edu)
  • Dr. Eirin and his colleagues are exploring the fundamental role of mitochondria in modulating stem cell biology and function. (mayo.edu)
  • DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) - biomolecular cousins - are fundamental molecules in cell biology. (yahoo.com)
  • In a scientific first, researchers said on Tuesday they have recovered RNA - genetic material present in all living cells that has structural similarities to DNA - from the desiccated skin and muscle of a Tasmanian tiger stored since 1891 at a museum in Stockholm. (yahoo.com)
  • Vittoria's proprietary cell therapy engineering and manufacturing platform, Senza5, combines the power of genetic engineering and a proprietary five-day manufacturing process. (tmcnet.com)
  • This is the multihit theory of tumorigenesis, in which a series of multiple triggering events in the genetic and cellular makeup of a cell ultimately cause cancer. (medscape.com)
  • We develop new technologies to characterize virus samples at the genetic, or most fundamental, level. (cdc.gov)
  • Hematopoietic stem cell lineage choices are decided by genetic networks that are turned ON/OFF in a switch-like manner. (lu.se)
  • yet they are crucial for understanding human biology and actualising the twenty-first century goal of personalized medicine through targeted clinical strategies for the mitigation and prevention of disease. (nature.com)
  • Applications span the full range from fundamental cell biology to applied clinical projects. (imperial.ac.uk)
  • In particular, most currently used culture conditions are not acceptable for standardized production of clinical grade cell products. (ca.gov)
  • Explore our diverse curriculum, bridging the gap between fundamental research and its translation into clinical practice. (lu.se)
  • A consistent theme within the course is micro- and nanostructures within biology and technology and their mutual connection. (lu.se)
  • We open new possibilities for fundamental studies in life science by designing nanostructures of relevance for cells and biomolecules. (lu.se)
  • I am a Professor in the Department of Biology at Queen's University. (queensu.ca)
  • Jung Hwan Kim is an Assistant professor in Biology department. (unr.edu)
  • MIT spinout Kronos Bio, founded by Associate Professor Angela Koehler, studies the complex signaling networks of cancer cells to find new drug targets. (mit.edu)
  • identify the complexity in the connections between dimensions in biology and the dimension of microelectronic devices and how this can be used when creating new tools for biomedical analysis. (lu.se)
  • The 11C1 monoclonal antibody recognizes CD268 which is also known as the B cell activating factor receptor (BAFF-R). CD268 is a type III transmembrane protein of approximately 184 residues. (bdbiosciences.com)
  • Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд. (wikipedia.org)
  • By using GFP reporters, we confirmed that tRNA changes impact to protein synthesis and thereby should be considered as a new regulatory layer in the cell. (europa.eu)
  • All these results support the idea that tRNA abundance is tightly controlled in the cell and this is reflected in a regulation of the protein synthesis in the ribosome. (europa.eu)
  • 2019) Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling. (lu.se)
  • Enzymes act as catalysts - they allow a reaction to proceed more rapidly - and they also allow the regulation of the rate of a metabolic reaction, for example in response to changes in the cell's environment or to signals from other cells. (wikipedia.org)
  • Therefore, uncover the molecular features and signaling pathways on tRNA that are responsible for tRNA regulation is of fundamental importance to understand the cell. (europa.eu)
  • A library of well-characterized, standardized and accessible hiPS cells from diverse ethnic populations would be a game-changer for both investigative and translational research on humans. (nature.com)
  • We are seeking to recruit a highly motivated, self-initiated applicant to join us as a postdoctoral research fellow in Dr. Tsuyoshi Hirashima's Collective Cell Dynamics in Mammalian Development and Reproduction lab. (timeshighereducation.com)
  • Although we remain skeptical about the possibility of actually recreating an extinct species using gene editing on living extant animal relatives - and the time-scale to get to a final point might be underestimated - we do advocate for more research on the biology of these extinct animals,' Mármol said. (yahoo.com)
  • T-cell lymphoma is a serious disease with a poor prognosis, and this investment aligns with our commitment to supporting cutting-edge research that offers promising treatments and hope for patients and their families. (tmcnet.com)
  • In turn, as a result of research into the abnormal cancer cell, the basic understanding of the cell has greatly improved. (medscape.com)
  • The Research School in Stem Cell Biology is a collaborative academic program that emphasizes high-quality research training and professional growth, offering a wide range of engaging educational activities to empower aspiring stem cell scientists and lay a solid foundation for their future success. (lu.se)
  • Our main research area comprises new generations of ionic polymers for proton- and anion-exchange membranes for energy conversion and storage systems such as fuel cells, water electrolyzers and flow batteries. (lu.se)
  • In a second research area, we explore new bio-based monomers, polymers and plastics synthesized using building blocks from renewable resources (mostly lignocellulose), as well as their degradation and recycling. (lu.se)
  • Introduction: Chimeric antigen receptors (CARs) can redirect T cells against antigen-expressing tumors, and each component plays an important role in the function and anti-tumor efficacy. (bvsalud.org)
  • One of our projects aims at investigating bacterial cell division as an antibiotic target. (lu.se)
  • Objective: This study aims to investigate the relationship between folic acid (FA) metabolic gene polymorphisms, homocysteine (Hcy), vitamin B12 (Vit B12), and red blood cell folate (RBCF) with adverse pregnancy. (bvsalud.org)
  • We look into the ways the factors that stimulate tumor growth (eg growth factors) signal to the interior of the cell, and how cancer cells communicate with their neighbors such as immune cells and vascular cells. (jhu.edu)
  • Department of Biology (i.e. a total of 60 credits per year). (lu.se)
  • Description: The Bimake Cell Counting Kit-8 (CCK-8) is a fluorescent assay for the determination of cell viability in vitro. (bioinfor.me)
  • An image depicting head and neck squamous cell carcinoma in vitro can be seen below. (medscape.com)
  • Head and neck squamous cell carcinoma in vitro (cell culture). (medscape.com)
  • Results: We have observed that moderately reducing the affinity of CARs (light chain variable domain (VL)-based CAR-T) could maintain the anti-tumor efficacy, and improved the safety of CAR therapy both in vitro and in vivo compared with high-affinity CAR-T cells. (bvsalud.org)
  • Moreover, T cells expressing the VL domain only antibody exhibited long-lasting tumor elimination capability after multiple challenges in vitro, longer persistence and lower cytokine levels in vivo. (bvsalud.org)
  • The knowledge about essential cell functions in bacteria and the experimental systems that we develop can be used to find new targets for antibiotics and to screen for molecules that can work as antibiotics. (lu.se)
  • The human body is a complex, highly organized structure made up of unique cells that work together to accomplish the specific functions necessary for sustaining life. (msdmanuals.com)
  • The cells in a tissue are not identical, but they work together to accomplish specific functions. (msdmanuals.com)
  • Using both chronological narratives and active learning to demystify science, the course aims to improve scientific literacy through an understanding of biology. (trentu.ca)
  • With this new phase we want to understand how the various genes and regulatory elements that make up the genome talk to each other and collaborate together in real-time to influence biology and disease. (umassmed.edu)
  • The shape it takes has a profound influence on which genes in a cell are turned on or turned off. (umassmed.edu)
  • At the time, the prevailing view was that genes provide a molecular blueprint that determines which cells become follicles and where these follicles form. (rockefeller.edu)
  • However, prior to commitment, it has been cells, it is evident that GATA-1 and PU.1 are able to specify observed that many genes are expressed at intermediate or basal erythroid and myeloid cell fates (see [16] and references therein). (lu.se)