• Chlamydia trachomatis are obligate intracellular bacterial pathogens that cause ocular and genital infections, which are a significant public health concern worldwide. (europa.eu)
  • The rapid growth and reproduction of these pathogens within the hospital environment highlight the urgent need to comprehend bacterial reproductive strategies and develop effective interventions. (echase.org)
  • By comprehending these mechanisms at a molecular level, scientists can devise strategies to combat harmful pathogens while harnessing the beneficial aspects of bacterial reproduction for various applications in medicine, industry, and agriculture. (echase.org)
  • Further, we study how intracellular C3 contributes to recognition and clearance of intracellular bacterial pathogens. (lu.se)
  • Because of the alarming and rising problems with antibiotic resistance among bacterial pathogens, there is an urgent need to rapidly develop new types of antibiotics and other anti-bacterial agents. (lu.se)
  • Today the IBM Functional Genomics Platform has approximately 220,000 high quality bacterial and viral genomes, 64 million unique genes, 50 million unique proteins, and over 220 million unique protein domains. (ibm.com)
  • DEC-205 (CD205), a member of the macrophage mannose receptor protein family, is the prototypic endocytic receptor of dendritic cells, whose ligands include phosphorothioated cytosine-guanosine (CpG) oligonucleotides, a motif often seen in bacterial or viral DNA. (uci.edu)
  • Problems relating to the lower respiratory system are generally a result of viral, bacterial or allergic reactions, which can result in a drop in performance from your horse. (yourhorse.co.uk)
  • A51/8 health (covering such aspects as administration, entomology, food hygiene, bacterial and viral diseases) and to ensure a wide geographical representation. (who.int)
  • Importantly, intravenous injection of ATc in zebrafish embryos infected with the rough mmpL3 conditional mutant impeded bacterial growth and correlated with a significant gain in embryo survival. (bvsalud.org)
  • Genome sequences of several strains from our bacterial collection from the marine, arctic environment have revealed their ability to synthesize different Sias, and represent a novel source for the prospecting of new gene variants. (uit.no)
  • Due to the psychrophilic nature of many of the bacterial strains they are likely to express cold active enzymes with high catalytic efficiency that additionally renders them as attractive targets for commercial exploitation. (uit.no)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • The evolution of various bacterial antibiotic resistance mechanisms means that new antimicrobial compounds are urgently needed. (warwick.ac.uk)
  • We use an interdisciplinary approach to study this area and explores the wide relationship between pathogenesis, bacterial growth and division, fundamental biological processes and antimicrobial strategies. (warwick.ac.uk)
  • Important applications can be built on top of the Functional Genomics Platform including services to annotate biological function in the microbiome, predict antimicrobial resistance (AMR), develop molecular targets for health interventions, or to expand our fundamental knowledge of microbial life. (ibm.com)
  • Moreover, studying bacterial growth kinetics facilitates the development of antimicrobial agents that target specific stages of replication or interfere with essential cellular processes. (echase.org)
  • The objective being to give an overview of the methods used in the discovery of molecular mechanisms used by model bacteria and the application of this in understanding the basic processes involved in bacterial growth and development in terms of regulation and biological function. (ncl.ac.uk)
  • She developed chemical probes to manipulate the intracellular organization of bacterial cells and created physical tools to engineer their growth environment and modulate their interactions with other cells. (harvard.edu)
  • The organization of bacterial cells is less complex than in higher developed cells. (mpg.de)
  • Cruz-Vera's analogy compares this process to a factory where products move through different stages, sometimes getting delayed by their own output-a phenomenon that has far-reaching implications for the lives of bacteria. (uah.edu)
  • This module provides an up to date understanding of how fundamental research in bacterial cell biology helps to elucidate central biological questions such as the control and regulation of cell division and of gene expression in bacteria. (ncl.ac.uk)
  • It will also provide an introduction into how understanding basic cellular processes can be used to understand the mechanisms by which antibiotics specifically inhibit certain bacteria and permit the identification of new targets for the development of novel antibiotics. (ncl.ac.uk)
  • Bacterial diseases can often be cured with antibiotics, but as most people know, the emergence of antibiotic-resistant bacteria is an increasing problem, and thus, novel antibiotics need to be developed. (sciencewatch.com)
  • One way to design effective antibiotics is to understand how the surface of the bacterium is formed, and then to use this knowledge to rationally design antibiotics that will enter the bacteria and inhibit essential processes necessary for their survival. (sciencewatch.com)
  • Datta and his colleagues hope their discoveries will aid a wide range of bacterial growth research, from creating more effective antimicrobials to pharmaceutical, medical and environmental research, as well as procedures that harness bacteria for industrial use. (solidstatelightingdesign.com)
  • Unlike those common versions of hydrogels, Data materials consist of very small spheres of hydrogel that are easily deformed by bacteria, allow free passage of oxygen and nutrients that support bacterial growth and are transparent to light. (solidstatelightingdesign.com)
  • Understanding how and why bacteria colonise particular sites is therefore a fundamental question with profound implications for health, biosecurity and food production. (ukri.org)
  • Cell-to-cell communication coordinates cellular activity and is therefore fundamental to the functioning of biological systems, including bacteria, and tissues of the human body, such as the brain. (nova.edu)
  • By uncovering the secrets behind bacterial reproductive strategies, researchers aim to devise innovative approaches for combating pathogenic bacteria while harnessing beneficial ones for biotechnological applications. (echase.org)
  • In this process, bacteria take up free DNA molecules from their surroundings and incorporate them into their own genome. (echase.org)
  • Here, we use bacterial abundance data of the marine model organism Nematostella vectensis to reconstruct potential bacteria-bacteria interactions through co-occurrence networks. (figshare.com)
  • Within 3 days of recolonization, all tested bacterial isolates affected bacterial community structure, while only competitive bacteria increased bacterial diversity. (figshare.com)
  • In comparison with similar proteins that build the cytoskeleton of bacteria, which are evolutionary older and simpler cells, the researchers found fundamental differences in the protein folding. (mpg.de)
  • The model organisms that we use, Gram-positive bacteria of the genus Streptomyces , provide unique possibilities to study some of these fundamental functions, and show several intriguing parallels to the corresponding processes in eukaryotic cells. (lu.se)
  • In the Weibel lab, Eun set out to expand the range of chemical and engineering tools for studying bacterial cell biology. (harvard.edu)
  • These effectors manipulate host cell processes to enable e. g. bacterial invasion, acquisition of nutrients, inhibition of apoptosis, or interference with immune signalling. (europa.eu)
  • One of our projects aims at investigating bacterial cell division as an antibiotic target. (lu.se)
  • Antibiotic stewardship is the process of ensuring that antibiotics are used appropriately. (medscape.com)
  • Best practices for antibiotic stewardship are built around several fundamental principles. (medscape.com)
  • Indeed, prescribing the wrong antibiotic, or at the wrong dose, can lead to bad outcomes for patients with bacterial infections. (medscape.com)
  • The lecture sequence will comprise of a module introduction followed by lectures on specific aspects of bacterial cell biology. (ncl.ac.uk)
  • On the other hand, uncontrolled bacterial replication can lead to harmful infections or outbreaks that pose significant threats to public health. (echase.org)
  • Pneumococcal Vaccine Pneumococcal vaccines help protect against bacterial infections caused by Streptococcus pneumoniae (pneumococci). (msdmanuals.com)
  • The structural studies of sialic acid synthesizing enzymes will aid to reveal possible importance of sialic acids for bacterial survival in the host, and in turn enable the development of highly selective antibiotics. (uit.no)
  • His research explores how this "factory" can get jammed and its impact on bacterial survival, unveiling a fundamental biological process. (uah.edu)
  • In this study, we report an experimental system in which E. coli evolves into a bacterial mutualist that supports survival and reproduction of P. stali , thereby demonstrating that evolution of mutualism can proceed very easily and quickly via disruption of a global transcriptional regulator system. (nature.com)
  • We found that C3 regulates process of autophagy and cell survival upon stress and now we aim to investigate what role C3 may play in β-cell physiology and islet inflammation. (lu.se)
  • I expect, especially from comparing these fundamental processes in different organisms, both experimentally and by in silico genome mining, to gain more insights. (sciencewatch.com)
  • What we found is that growth in 3D bacterial colonies exhibit a very similar process despite the fact that these are groups of organisms. (solidstatelightingdesign.com)
  • Reproduction is the biological process by which new individual organisms are produced. (sciforums.com)
  • The maintenance and resilience of host-associated microbiota during development is a fundamental process influencing the fitness of many organisms. (figshare.com)
  • Vascular compromise of the cystic artery renders the gallbladder ischemic and facilitates the proliferation of gas-forming organisms and bacterial translocation in the devitalized tissue with low oxygen saturation. (medscape.com)
  • The interplay of lipids and membrane proteins is crucial for numerous fundamental processes ranging from respiration, photosynthesis, signal transduction, solute transport to motility. (pasteur.fr)
  • Typically, proteins spontaneously find their fold - chaperones just assist them by making the process more effective and keeping the protein away from interactions that would hamper folding. (mpg.de)
  • Actin has many more protein interaction partners than the bacterial cytoskeletal proteins, but it has lost the ability to fold independently. (mpg.de)
  • Bacterial cytoskeletal proteins also require the help of chaperones to effectively reach a folded state. (mpg.de)
  • Processes like these have evolved from common ancestors of both eukaryotes and prokaryotes, and it becomes increasingly clear that the bacterial versions of these basic cell functions use similar ancestral molecules, for example cytoskeletal proteins, as those used in animal and plant cells. (lu.se)
  • A thorough understanding of the fundamental principles of biofilm generation would help to prevent biofouling. (tau.ac.il)
  • Then, biophysical studies of its interaction with eukaryotic and bacterial model membranes were carried out. (unina.it)
  • In collaboration with Martin Thanbichler's group at the Max Planck Institute for Terrestrial Microbiology, she discovered two compounds, DCAP and divin, from a high-throughput small molecule screen and determined that they perturb the organization of bacterial membranes and cell division. (harvard.edu)
  • The researchers were able to observe the clumpy growth of the bacterial colonies in three dimensions. (solidstatelightingdesign.com)
  • At a fundamental level, we are excited that this work is revealing surprising connections between the evolution of form and function in biological systems and studies of non-living growth processes in materials science and statistical physics. (solidstatelightingdesign.com)
  • But we also believe that this new insight into when and where cells grow in 3D will be of interest to any Someone interested in bacterial growth, such as in environmental, industrial, and biomedical applications," Datta said. (solidstatelightingdesign.com)
  • The hydrogel is strong enough to support bacterial colony growth without introducing resistance. (solidstatelightingdesign.com)
  • Such natural processes as illness, death, growth and decay, earthquakes, the seasons, confront us with things which are often beyond our ability to control. (dreamhawk.com)
  • These mutants exhibited slower bacterial growth, smaller size, loss of flagellar motility and lack of an extracellular matrix. (nature.com)
  • Different physiological processes are analyzed using various techniques, e.g. investigation of microbial growth under oxic and anoxic conditions, determination of protein contents and measurement of substrate turnover rates. (uni-oldenburg.de)
  • Bacterial growth and reproduction are fundamental processes in microbiology that have been the subject of extensive research. (echase.org)
  • Consequently, studying bacterial growth and reproduction has become an area of immense interest among scientists seeking to unravel key molecular mechanisms involved in these processes. (echase.org)
  • In this article, we delve into the fascinating world of bacterial growth and reproduction from a microbial perspective. (echase.org)
  • In summary, bacterial growth and reproduction are fundamental aspects of microbiology with significant implications for human health and environmental processes. (echase.org)
  • The concentration of suspended solids from airborne particulates and other sources also increases, facilitating biological fouling and risking bacterial growth. (facilitymanagement.com)
  • The focus of our group is upon the enzymes and pathways required for bacterial cell wall biosynthesis and their relationship to the bacterial cell division thus spanning process that occur on both sides of the cytoplasmic membrane. (warwick.ac.uk)
  • A good AMP should interact selectively with the bacterial membrane, should not be toxic to eukaryotic cells and should be resistant to proteases degradation. (unina.it)
  • In the chapter 4 is reported the biophysical characterization of the interaction of two P9Nal(SS)-derived peptides, named P9Nal(SR) and P9Trp(SS), with liposomes mimicking bacterial membrane. (unina.it)
  • A research team led by Prof. Holger Gohlke at the Heinrich Heine University Düsseldorf is using supercomputing resources at the Jülich Supercomputing Centre (JSC) to better understand so-called hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which serve as crucial ion channels in the membrane for controlling electric pulses in the brain and heart, among other fundamental processes in the body. (gauss-centre.eu)
  • The overall scientific objective of this project was to increase our fundamental understanding of mechanisms underlying C. trachomatis virulence. (europa.eu)
  • You will gain hands-on experience in planning and conducting laboratory experiments that address fundamental cellular mechanisms underlying physiological and disease processes. (lu.se)
  • This project aims to increase our fundamental understanding of the roles of bacterial Sias in host-pathogen interactions, and to characterize biosynthetic pathways and enzymes involved in sialic acid synthesis. (uit.no)
  • A fundamental virology background will be achieved by understanding the diversity of viruses, their replication strategies and their interactions with the host in disease. (uoguelph.ca)
  • To assess the predictive power of inferred interactions, we tested bacterial isolates with predicted cooperative or competitive behavior for their ability to influence bacterial recolonization dynamics. (figshare.com)
  • Medical Bacteriology takes a specimen-based approach: bacterial diseases and their causative agents are addressed through the proper collection, processing, and analysis of clinical specimens. (cdc.gov)
  • I became involved in research on bacterial infectious diseases when John Swanson, then head of the laboratory of Microbial Structure and Function at the Rocky Mountain Laboratories of the National Institute of Allergy and Infectious Diseases, NIH, Hamilton, MT, offered me the opportunity to do a post-doc in his lab. (sciencewatch.com)
  • In renewing IHR, the original fundamental principle - to ensure maximum security against the international spread of diseases with minimum interference with world traffic and trade - will be retained. (who.int)
  • Biochemical studies indicated that the addition of ATc was associated with a dose-dependent decrease in (i) the production of the MmpL3 protein, (ii) the biosynthesis of trehalose dimycolate and mycolylated arabinogalactan, (iii) bacterial viability on agar and liquid medium as well as in biofilms. (bvsalud.org)
  • Sialic acids (Sias) are carbohydrates with immensely important roles in biological, pathological and immunological processes. (uit.no)
  • The bacterial contribution to health and the environment is enormous with central roles in processes as diverse and important as immune development and nutrient cycling. (ukri.org)
  • Our recent work has focused on analysing the roles of both bacterial and host metabolism in affecting bacterial gene expression. (ukri.org)
  • Our data further support the role of ppGpp participating in the coordinated regulation of the expression of bacterial factors required during infection. (ibecbarcelona.eu)
  • Imagine a scenario where an individual contracts a bacterial infection. (echase.org)
  • Periodontal disease is a chronic bacterial infection that affects the gingiva and bone that supports the teeth. (bvsalud.org)
  • You will also be introduced to the key emerging technological developments, such as next generation sequencing and the concept of the microbiome as well as the role of CRISPR as a bacterial defence system. (manchester.ac.uk)
  • To uncover CTCF's role in this process they used CRISPR genome editing tools to degrade the protein and study changes in genome organization as the cell fate changes. (scitechdaily.com)
  • Multiple options exist for presenting the fundamentals of medical bacteriology. (cdc.gov)
  • Fundamentals of Bacteriology will provide you with a detailed understanding of bacterial cell structure including a particular focus on the cell surface. (manchester.ac.uk)
  • Research into micro- and nano-biological processes has spiked in the last few decades due to technological advances and new methods for visualizing molecules and events within cells. (nova.edu)
  • If a model microbe like Escherichia coli with elaborate molecular genetic tools and resources can establish a mutualistic association with a host organism via experimental evolution, such a 'model experimental symbiotic system' will be extremely useful for understanding the evolutionary processes of symbiosis towards mutualism. (nature.com)
  • The characteristics of fungal cell structure, genetics and metabolism will be presented, and fungal reproduction and sporulation processes discussed with reference to the life cycles of representative forms. (uoguelph.ca)
  • It will also look at aspects of the interaction of bacterial spp. (ncl.ac.uk)
  • Prokaryotes have attracted the interests of researchers not only because the processes taking place in their world are important to cells, but also because many of the effects often can be readily measured, both at the single cell level and in large populations. (ibecbarcelona.eu)
  • Importantly, the researchers also found that CTCF depletion impairs a cell's ability to have a full-blown inflammatory response in the presence of bacterial endotoxin. (scitechdaily.com)
  • Using the JURECA supercomputer, a team of University of Cologne researchers led by Prof. Dr. Joseph Kambeitz is simulating biophysical processes in the brain in pursuit of better understanding what leads to schizophrenia in patients. (gauss-centre.eu)
  • In order to gain a fundamental understanding of the process, the researchers ran computationally intensive molecular dynamics simulations of up to 600,000 atoms. (gauss-centre.eu)
  • Bacterial identification and characterization protocols are based on techniques that have been in general use for many years. (cdc.gov)
  • Eun's work introduced the first thermodynamic and kinetic characterization of a prokaryotic globin, and suggested that the general folding features of bacterial and eukaryotic globins are preserved through evolution while kinetic details differ. (harvard.edu)
  • When it comes to the causal relationship between the gut microbiome and obesity, the strongest available evidence has emerged from rodent models where it has been demonstrated that fecal microbiota transplantation can transfer the obese phenotype and that the gut microbiome plays a fundamental role in harvesting energy from the diet. (medscape.com)
  • O queijo de coalho é um produto tradicional do nordeste brasileiro e o conhecimento da sua microbiota autóctone é de fundamental importância. (bvsalud.org)
  • Several host properties were identified as influencing factors on bacterial colonization, including the innate immune system, mucus composition, and diet. (figshare.com)
  • Another set of cloud processes discover all of the domains within each protein. (ibm.com)
  • Protein domains are fundamental objects of biochemistry delivering the biological activity of the microorganism. (ibm.com)
  • Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle contractions. (mpg.de)
  • Your horse's lungs and respiratory system process air, which is fundamental in providing oxygen for life and performance," states Gillian Higgins from Horses Inside Out. (yourhorse.co.uk)
  • In RIT's biotechnology and molecular biology degree you'll improve human health by harnessing technology advancements and biomolecular processes to research and develop technologies in genetics, agriculture, pharmaceuticals and vaccine development, environment and energy, forensic science, genetic counseling, and more. (rit.edu)
  • They are also assigned standardized codes representing their molecular function, cellular component, and biological process they are associated with. (ibm.com)
  • For a researcher armed with the powerful tools of genetics and molecular biology, the simple bacterial cells provide great experimental systems for investigating fundamental functions of a living cell. (lu.se)
  • Homologous recombination is widely used by cells to accurately repair harmful DNA breaks that occur on both strands of DNA, known as double-strand breaks (DSB), in a process called homologous recombinational repair (HRR). (wikipedia.org)
  • Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes make gamete cells, like sperm and egg cells in animals. (wikipedia.org)
  • Two decades later, Barbara McClintock and Harriet Creighton demonstrated that chromosomal crossover occurs during meiosis, the process of cell division by which sperm and egg cells are made. (wikipedia.org)
  • Following initial formation and stabilization of the Z-ring, cells must complete segregation of the bacterial chromosome and remodel the cell envelope to allow septum formation. (uoguelph.ca)
  • The division of a bacterial cell into two daughter cells is an example of asexual reproduction. (sciforums.com)
  • Binary fission is the most common form of bacterial reproduction, whereby a single bacterium divides into two identical daughter cells. (echase.org)
  • Conjugation is another important mode of bacterial reproduction that involves the transfer of genetic material between two bacterial cells. (echase.org)
  • Recently, the stinkbug Plautia stali (Hemiptera: Pentatomidae) has emerged as an experimentally tractable model system for investigating the diversity, evolution and mechanism of gut symbiosis with bacterial mutualists 10 , 11 . (nature.com)
  • Only 1 week after recolonization, almost no differences in bacterial community structure could be observed between control and treatments. (figshare.com)
  • Factors that can increase susceptibility include age-related differences in how the body processes (metabolizes) and uses many medications. (msdmanuals.com)
  • We have found that the amino acid D-serine drives niche adaptation and bacterial evolution by affecting gene selection in E. coli. (ukri.org)
  • Metabolites, on the other hand, are chemicals that participate in life processes later and can more directly reflect dynamic changes in the body ( 18 ). (frontiersin.org)
  • For example, in the petrochemicals industry, MS paired with GC (GC-MS) is used at multiple stages of the prospecting, refining, formulation and QC process to identify contaminants, determine the ratios of the constituent chemicals and make process improvements among other things. (technologynetworks.com)
  • A model of residual chlorine decay in water pipe has been developed, given the consumption of chlorine in reactions with chemicals in bulk water, bio-films on pipe wall, in corrosion process, and the mass transport of chlorine from bulk water to pipe wall. (who.int)
  • In the search for life elsewhere in the solar system, we have some expectations about what life might look like: It will likely involve carbon chemistry, and a spatial segregation of organic compounds in a way that simple chemical processes would not permit. (nationalacademies.org)
  • The scientific motivation for the research was an interest in better understanding nitrogen fixation-that is, the chemical processes by which atmospheric nitrogen is assimilated into organic compounds as part of the nitrogen cycle. (phys.org)
  • Designed for doctors with at least one year of general medical experience, this MSc offers a structured education in dermatology and gives a firm grounding in the fundamentals of clinical and scientific dermatology. (cardiff.ac.uk)
  • Studying CTCF helps us understand the glue that holds the genome together, and by proxy the role of 3-D genomic architecture in various fundamental processes in life. (scitechdaily.com)
  • Bacterial cell division is an essential and fundamental process required to sustain life. (uoguelph.ca)
  • The use of gene editing techniques in lieu of inserting transgenes into the A. vinelandii genome allowed regulatory requirements to be avoided that would have made the development process slower, and more difficult and expensive. (phys.org)
  • To screen for novel T3S effectors of C. trachomatis, we used Yersinia enterocolitica as a genetically tractable surrogate bacterial species assembling a T3S apparatus, which has been shown to recognise heterologous T3S substrates. (europa.eu)
  • A brief description of the influence of biofouling in water treatment, food processing, and biomedical devices has been provided. (tau.ac.il)
  • I hope my research will contribute significantly to an overall fundamental understanding of how bacterial surfaces are formed. (sciencewatch.com)
  • Data's research group discovered this behavior using a pioneering experimental setup that enables them to make previously unheard-of observations of bacterial colonies in their natural, three-dimensional state. (solidstatelightingdesign.com)
  • In a new publication in Nature Communications, a team from the Dutch company Syngaschem BV and the Dutch Institute for Fundamental Energy Research elucidates for the first time some aspects of the Fischer-Tropsch reaction, used for converting synthesis gas into synthetic fuels. (lu.se)
  • After a double-strand break occurs, sections of DNA around the 5' ends of the break are cut away in a process called resection. (wikipedia.org)
  • Bacterial reproduction occurs through a process called binary fission. (echase.org)
  • Our work helps provide a more complete, fundamental understanding of the factors that underpin gene expression in a model nitrogen fixing microorganism and defines the biochemistry that brings about ammonia excretion in A. vinelandii," said Mus. (phys.org)